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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Jurnal Riset Kesehatan Majalah Kedokteran Gigi Indonesia ODONTO Dental Journal Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry Journal of Indonesian Dental Association Seminar Nasional Lahan Suboptimal JITEKGI Jurnal Ilmiah dan Teknologi Kedokteran Gigi E-Prodenta Journal of Dentistry JPP Jurnal Kesehatan Poltekkes Palembang Jurnal 'Aisyiyah Medika MDJ (Makassar Dental Journal) Jurnal Kesehatan Gigi dan Mulut (JKGM) Denta: Jurnal Kedokteran Gigi Cerdika: Jurnal Ilmiah Indonesia Cakradonya Dental Journal Odonto dental journal Jurnal INFOTEL
Siti Rusdiana Puspa Dewi
Department Of Biomedical Science, Dentistry Study Programme, Faculty Of Medicine, Universitas Sriwijaya, Palembang, South Sumatra
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Oral Pseudomembrane Kandidiasis in Nasopharynx Cancer - A Case Report Dewi, Siti Rusdiana Puspa; Maulina, Shania Tri
Journal of Indonesian Dental Association Vol 8 No 1 (2025): May
Publisher : Indonesian Dental Association

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32793/jida.v8i1.1222

Abstract

Introduction. Nasopharyngeal cancer (NPC) is a malignant condition of the nasopharynx. The cancer therapy given is usually radiotherapy (RT), chemotherapy (CT), or a combination of RT and CT. Cancer therapy and poor oral hygiene can lead to susceptibility to fungal infections, one of which is pseudomembranous kandidiasis (thrush). The aim of this report was to present oral pseudomembrane kandidiasis patient with nasopharynx cancer. Case report. A 52-year-old female patient was referred to the hospital's dental clinic with complaints of a white coating on the inside of her cheeks, roof of the mouth, and tongue since ± 1 week ago. The patient feels pain when swallowing and discomfort when opening the mouth. The results of clinical and supporting examinations showed that the patient was diagnosed with oral pseudomembranous kandidiasis. The patient was treated using nystatin drop and chlorhexidine gluconate 0.2% Conclusion. The NPC patient in this case was diagnosed with pseudomembranous kandidiasis (thrush) caused by Candida albicans. Early management of cases of pseudomembranous kandidiasis in NPC patients was very important so that the lesion would not disrupt the general condition of the patient as a whole. Collaboration and coordination from various specialist divisions were needed.
3D Dentobox (Dental Explosion Box 3D) as education media for children caries prevention Dewi, Siti Rusdiana Puspa; Utami AF, Deratih Putri; Octantia, Indah; Ifadah, Nurul
Padjadjaran Journal of Dentistry Vol 29, No 2 (2017): July 2017
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (195.232 KB) | DOI: 10.24198/pjd.vol29no2.13604

Abstract

Introduction: The most common dental and oral health problem in the world is dental caries. In Indonesia, as many as 89% of children under 12 years old suffered from dental and oral disease. Lack of dental knowledge and awareness can be overcome by conducting intensive dental and health education to the community. 3D Dentobox is a simple three-dimensional game designed to deliver dental and oral health messages, including dental hygiene, ways to overcome dental health problems and some dental games. 3D Dentobox is an educational media prevention of caries in children. Methods: The method used was Quasi experiment with the type of pretest and posttest control group design. The sample of this study was 30 children aged 9-12 years old. The research subjects filled out a questionnaire containing information on the level of knowledge, attitudes, and actions in caries prevention efforts followed by outreaching to the media and 3D props Dentobox and was given back the same questionnaire to be filled. Data were collected and evaluated using Guttman scale and was analyzed by paired T test. Results: The results showed that the average level of knowledge, changing attitudes, and actions before and after use 3D Dentobox increased significantly (p<0.05). Conclusion: 3D Dentobox can be used as a media of education to prevent dental caries in children.
PENGARUH KOMBINASI EKSTRAK KULIT BUAH DURIAN DAN ITRACONAZOLE DALAM MENGHAMBAT PERTUMBUHAN Candida albicans Puspa Dewi, Siti Rusdiana; Sukmawan, Ahdiyat; Farianty, Lizzana
Cakradonya Dental Journal Vol 11, No 2 (2019): Agustus 2019
Publisher : FKG Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/cdj.v11i2.12643

Abstract

Itraconazole merupakan salah satu obat sintetik yang memiliki keterbatasan dalam menghambat pertumbuhan Candida albicans (C. albicans). Kulit buah durian (Durio zibethinus L.) merupakan salah satu tanaman yang memiliki efek antifungal karena mengandung senyawa organik seperti flavonoid, tannin, dan saponin yang mampu menghambat pertumbuhan C. albicans. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh kombinasi ekstrak kulit buah durian dan itraconazole dalam menghambat pertumbuhan C. albicans. Penelitian ini menggunakan metode checkerboard dengan 6 jenis konsentrasi ekstrak kulit buah durian dan 5 jenis konsentrasi itraconazole dalam menentukan KHM kombinasi. KHM kombinasi diuji pada media SDA untuk mengetahui pengaruh kombinasi terhadap C. albicans melalui zona hambat yang dibandingkan dengan itraconazole, ekstrak kulit buah durian, dan akuades. Hasil dari penelitian didapatkan bahwa KHM kombinasi adalah ekstrak kulit buah durian 25% dan itraconazole 4 g/ml. Semakin meningkatan konsentrasi kulit buah durian dan dosis itraconazole, maka semakin meningkat pula daya hambat terhadap pertumbuhan C. albicans. Kesimpulan dari penelitian ini adalah kombinasi ekstrak kulit buah durian dengan itraconazole meningkatkan kemampuan dalam menghambat pertumbuhan C. albicans.
PENATALAKSANAAN MUKOBIOADHESIF EKSTRAK GAMBIR (Uncaria gambir) TERHADAP LESI ULSERASI RONGGA MULUT Puspa Dewi, Siti Rusdiana; Handayani, Pudji; Tyas, Hestiningsih; Destriarum, Destriarum; Sari, Adelina Putri
Cakradonya Dental Journal Vol 13, No 2 (2021): Agustus 2021
Publisher : FKG Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24815/cdj.v13i2.19279

Abstract

Lesi ulserasi merupakan penyakit jaringan lunak mulut yang banyak dijumpai. Pendekatan perawatan terhadap lesi ulserasi dengan menggunakan bioadhesif bertujuan untuk mendapatkan efek terapi maksimal dari suatu zat aktif. Tanaman gambir (Uncaria gambir) adalah suatu jenis tanaman yang banyak dikembangkan sebagai obat herbal karena memiliki senyawa aktif seperti katekin. Tujuan dari penelitian ini adalah untuk mengevaluasi efek mukobioadhesif ekstrak gambir terhadap lesi ulserasi rongga mulut. Penelitianini menggunakan metode pretest-posttestcontrol group. 24 sampel dibagi menjadi dua kelompok, kelompok yang diberi mukobioadhesif ekstrak gambir dan kelompok yang diberi mukobioadhesif plasebo selama 7 hari dengan aturan pakai 3 kali sehari. Tingkat keparahan rasa sakit yang diukur dengan skala VAS, luas lesi ulserasi, dan durasi penyembuhan dievaluasi dan dianalisis dengan SPSS ver. 22. Hasil penelitian menunjukkan bahwa penggunaan mukobiadhesif ekstrak gambir mampu mengurangi rasa sakit dan luas lesi, serta mampu menurunkan durasi penyembuhan secara signifikan dibandingkan dengan plasebo. Dapat disimpulkan bahwa penatalaksanaan mukobioadhesif ekstrak gambir berpotensi dalam mengurangi rasa sakit dan mempercepat penyembuhan lesi ulserasi rongga mulut.
A Combination of 10% Gambier Extract and 0.0048% Fluoride Toothpaste as An Alternative Antifungal Therapy Handayani, Pudji; Denhari Aflah, Muhammad Naufal; Puspa Dewi, Siti Rusdiana
Cerdika: Jurnal Ilmiah Indonesia Vol. 2 No. 7 (2022): Cerdika: Jurnal Ilmiah Indonesia
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/cerdika.v2i7.412

Abstract

Poor oral hygiene might lead to Candida albicans infection. Since long term used of synthetics antifungal therapy could lead to fungal resistance, an alternative of antifungal therapy was needed. It has been reported that Gambier (Uncaria gambir ROXB) contains catechins and tannins which have antifungal effects invitro, but research using Gambier extract as a toothpaste for daily oral hygiene maintenance has not established. This study was done to determine the antifungal effect and the synergy of the combination of 10% gambier and fluorides in toothpaste preparation against Candida albicans. A true experimental laboratory study with a post-test-only design group was established. Three groups namely 10% gambier extract toothpaste, the combination of 10% gambier extract and 0.0048% fluorides toothpaste, lastly the 0.0048% fluoride toothpaste were tested. Gambier extract was obtained using the soxhletation method and the separation of the solvent from the extract was carried out by the distillation method. Agar Well method antifungal test was used to measure the inhibition zone value of tested groups. Data were analyzed using one-way Anova. Inhibition test of tested groups showed that only combination of gambier and fluorides toothpaste was effective in inhibiting Candida albicans with an average inhibition zone value of 8.35 mm. Toothpaste preparation of 10% Gambier extract and 0.0048% fluorides combination produce a synergistic therapeutic effect in antifungal therapy.
Pembelajaran Ensemble Voting Tertimbang dari Arsitektur CNN untuk Klasifikasi Retinopati Diabetik Desiani, Anita; Primartha, Rifkie; Hanum, Herlina; Dewi, Siti Rusdiana Puspa; Suprihatin, Bambang; Al-Filambany, Muhammad Gibran; Suedarmin, Muhammad
JURNAL INFOTEL Vol 16 No 1 (2024): February 2024
Publisher : LPPM INSTITUT TEKNOLOGI TELKOM PURWOKERTO

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20895/infotel.v16i1.999

Abstract

Diabetic Retinopathy (DR) is a diabetes disease that attacks the retina of the eye and can be recognized through retinal images. The process of assisting retinal images can be done by applying deep learning-based methods, one of which is the Convolutional Neural Network (CNN). CNN has many architectures that can perform image classification processes, namely ResNet-50, MobileNet, and EfficientNet. Weaknesses of each architecture can be overcome through ensemble learning methods that can add up the performance results of each classification method. The study applies the ensemble learning method to improve the performance of the ResNet-50, MobileNet, and EfficientNet architectures in paying for DR disease on the retina by weighted voting. The data used are the APTOS and EyePACS datasets. The method in this research is data collection, training, testing, and evaluation of each architecture and ensemble learning. The results of the superior ensemble learning performance in the value of accuracy, F1-Score, and Cohens Kappa were obtained respectively 93.3%, 93.42%, and 0.866. The best specificity value was obtained by Resnet-50 at 99.78% and the highest sensitivity value was obtained by EfficientNet at 96.2%. Based on the classification results of each architectural and ensemble learning, it can be interpreted that the proposed ensemble learning method is excellent to perform image classification for Diabetic Retinopathy.
Evaluation of Antibacterial Activity of Cymbopogon Nardus L. on The Growth of Enterococcus Faecalis Rosada Sintya Dwi; Diah Tanjung; Shanty Chairani; Rini Bikarindrasari; Siti Rusdiana Puspa Dewi
Denta Journal Kedokteran Gigi Vol 15 No 1 (2021): Februari
Publisher : Fakultas Kedokteran Gigi Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/denta.v15i1.4

Abstract

Background: Cymbopogon nardus L. known as citronella grass is traditional medicinal plant that contains saponins, polyphenols, alkaloids, flavonoids, and essential oil. Based on the previous study, it is known that it has antibacterial properties. Objective: The aim of this study was to determine antibacterial activity of Cymbopogon nardus L. in inhibiting the growth of Enterococcus faecalis. Methods: The samples were Cymbopogon nardus L. extracts with concentration of 1%, 3%, 5%,7%, 9%, and 5% NaOCl as positive control. Antibacterial activity of citronella extract against E. faecalis was observed with the formation of inhibitory zone diameter in agar. Data were analyzed using SPSS with one-way ANOVA and LSD test. Result: The result showed that Cymbopogon nardus L. was able to inhibit the growth of E. faecalis at concentration 1%,3%,5%,7% and 9%. There was a significant difference in antibacterial activity among all groups. It showed that concentration of 9% showed the highest zone of inhibition, but it was not as effective as NaOCl 5%. NaOCl showed the highest zone of inhibition. Conclusion: Cymbopogon nardus L. had antibacterial activity in inhibiting the growth of E. faecalis. The higher the concentration of citronella extract, the higher the antibacterial activity possessed.
Co-Authors Abu Bakar Lutfi Adelina Putri Sari Ahdiyat Sukmawan Ahmad Rama Biran Al-Filambany, Muhammad Gibran Amarel, Fahma Alfarizqy Angraini, Mona Rizki Anin Esta Rauna Anita Desiani Anna Pratiwi Arya Prasetya Beumaputra Arya Prasetya Beumaputra Bambang Suprihatin Billy Sujatmiko Budi Santoso Debby Handayani Harahap Denhari Aflah, Muhammad Naufal Deratih Putri Utami AF, Deratih Putri Destriarum Destriarum Destriarum, Destriarum Diah Tanjung Dina Oktaviani Marlamsya Dwi Budi Santoso Fahma Alfarizqy Amarel Farianty, Lizzana Ferdinan, Muhammad Handayani, Pudji Harahap, Debby Handayani Herlina Hanum, Herlina Hestiningsih, Tyas Hutami, Rizka Adianti Indah Octantia, Indah Indira, Tissa Irfannuddin Irfannuddin Lasma Evi Lany Legiran Legiran Lidya Astri Lizzana Farianty Lutfi, Abu Bakar Maulina, Shania Tri Maya Hudiyati Mayang Pramudya Sari Mozartha, Martha Nurul Ifadah, Nurul Pudji Handayani Rifkie Primartha Rindit Pambayun Rindit Pambayun Rini Bikarindrasari Rini Bikarindrasari Rini Bikarindrasari, Rini Rosada Sintya Dwi Rosada Sintya Dwi Sari, Adelina Putri Shanty Chairani Sherly Septhimoranie Sri Wahyuningsih Rais Sri Wahyuningsih Rais Suedarmin, Muhammad Sujatmiko, Billy Sukmawan, Ahdiyat Suryadi Muchzal Teodorus Teodorus Theodorus Theodorus Tiara Samapta Dewi Tissa Indira Tri Wardani Widowati Trisnawaty K Tyas Hestiningsih Tyas, Hestiningsih Veronita Veronita Veronita, Veronita Wulan Oktaviani Yeza Safitri