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All Journal Dinamika Akuntansi Keuangan dan Perbankan Jurnal Paradigma Ekonomika Medula Midwifery Journal: Jurnal Kebidanan UM. Mataram Manuju : Malahayati Nursing Journal Jurnal Bidan Cerdas Lentera Acitya Journal Of Health Best Journal (Biology Education, Sains and Technology) INVEST : Jurnal Inovasi Bisnis dan Akuntansi Jurnal Kesehatan Tambusai Indo-MathEdu Intellectuals Journal Indonesian Journal of Nursing and Health Sciences (IJNHS) Innovative: Journal Of Social Science Research Molekul: Jurnal Ilmiah Kimia Jurnal Kesehatan Lentera Acitya JER Holistik Jurnal Kesehatan Journal of Asian-african Focus in Health Tirai Edukasi : Jurnal Pendidikan JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Adaptive Governance Research

Susianti, Susianti

Universitas Mega Buana Palopo

Author-ID : 2560441

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Faktor-faktor yang memengaruhi hipertensi pada lansia Soraya, Yeni; Susianti, Susianti; Suwandi, Jhons Fatriyadi
Holistik Jurnal Kesehatan Vol. 19 No. 3 (2025): Volume 19 Nomor 3
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/hjk.v19i3.905

Background: Hypertension is one of the non-communicable diseases (NCDs) that is the leading cause of death globally. Lampung Province recorded a prevalence of hypertension of 29.9% with a significant burden of cases in the elderly group. Purpose: To analyze the factors that influence the incidence of hypertension in the elderly. Method: This cross-sectional analytical survey study was conducted at the Tresna Werdha home for the elderly and Tanjung Sari Health Center, Natar District, South Lampung in May-June 2024. The study population was 176 elderly people, consisting of 80 elderly from Panti Tresna Werdha and 96 elderly from Tanjung Sari Health Center. Data analysis was carried out using a logistic regression test with a significance level of α <0.05. Results: Showed that in the health center group, significant variables associated with hypertension included a history of hypertension (OR: 217), vegetable and fruit consumption (OR: 3,735), oil consumption (OR: 93,444), and salt consumption (OR: 3,182). Meanwhile, in the home for the elderly group, significant variables included a history of hypertension (OR: 3.567), physical activity (OR: 4.660), social activity (OR: 14.538), social interaction (OR: 6.152), and mental status (OR: 3.462). Conclusion: Hereditary factors, consumption patterns, and social and mental aspects contribute greatly to the incidence of hypertension in the elderly. Community-based interventions and strengthening healthy lifestyles are needed to reduce the prevalence of hypertension in the elderly. Keywords: Hypertension; Elderly; Non-Communicable Diseases (NCDs). Pendahuluan: Hipertensi merupakan salah satu penyakit tidak menular (PTM) yang menjadi penyebab kematian tertinggi secara global. Provinsi Lampung mencatat prevalensi hipertensi sebesar 29.9% dengan beban kasus yang signifikan pada kelompok lansia. Tujuan: Untuk menganalisis faktor-faktor yang memengaruhi kejadian hipertensi pada lansia. Metode: Penelitian survei analitik cross sectional, dilakukan di Panti Tresna Werdha dan Puskesmas Tanjung Sari Kecamatan Natar Lampung Selatan pada bulan Mei-Juni 2024. Populasi adalah orang lansia berjumlah 176 orang yang berasal dari Panti Tresna Werdha berjumlah 80 lansia dan Puskesmas Tanjung Sari berjumlah 96 lansia. Analisis data dilakukan menggunakan uji regresi logistik dengan tingkat signifikansi α<0.05. Hasil: Menunjukkan bahwa pada kelompok puskesmas, variabel signifikan yang berhubungan dengan hipertensi meliputi riwayat hipertensi (OR: 217), konsumsi sayur dan buah (OR: 3.735), konsumsi minyak (OR: 93.444), dan konsumsi garam (OR: 3.182). Sementara pada kelompok panti, variabel yang signifikan mencakup riwayat hipertensi (OR: 3.567), aktivitas fisik (OR: 4.660), aktivitas sosial (OR: 14.538), interaksi sosial (OR: 6.152), dan status mental (OR: 3.462). Simpulan: Faktor keturunan, pola konsumsi, serta aspek sosial dan mental berkontribusi besar terhadap kejadian hipertensi pada lansia. Intervensi berbasis komunitas dan penguatan pola hidup sehat sangat diperlukan untuk menekan prevalensi hipertensi di kalangan lanjut usia. Kata Kunci: Hipertensi; Lansia; Penyakit Tidak Menular (PTM).

HUBUNGAN PEMBERIAN ASI DAN BERAT BADAN LAHIR DENGAN KEJADIAN IKTERUS NEONATORUM DI RSUD ANDI MAKKASAU Irawati, Ayu; Susianti, Susianti; Usman, Arifa; Azis, Sukmawati
Jurnal Kesehatan Lentera Acitya Vol 12, No 1 (2025): Jurnal Kesehatan Lentera Acitya
Publisher : FATIMA PAREPARE HEALTH SCIENCE COLLEGE

Show Abstract | Download Original | Original Source | Check in Google Scholar

Efek Protektif Ekstrak Daun Jambu Air (Syzygium Aqueum) terhadap Kerusakan Lambung Tikus Putih Jantan (Rattus Norvegicus) Galur Wistar yang Diinduksi Indometasin Justisia, Adilla; Susianti, Susianti; Jausal, Anisa Nuraisa; Busman, Hendri
Malahayati Nursing Journal Vol 7, No 8 (2025): Volume 7 Nomor 8 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v7i8.21126

ABSTRACT The prevalence of peptic ulcers caused by the use of Nonsteroidal Anti-Inflammatory Drugs (NSAID) has increased over the past 10 years. Oxidative stress induced by NSAID can trigger the formation of peptic ulcers. The objective of this research was to determine the protective effect of water apple leaf extract (Syzygium aqueum) on gastric damage of male white rats (Rattus norvegicus) wistar strain induced by indomethacin. This laboratory experimental study with a randomized post-test only control group design involved 24 male Wistar strain white rats divided into 6 groups. Group K(0) was given food and water, K(-) was administered indomethacin at a dose of 30 mg/kgBW, K(+) received vitamin C at a dose of 9 mg/kgBW and indomethacin at 30 mg/kgBW, while P1, P2, and P3 were given water apple leaf extract at doses of 100 mg/kgBW, 300 mg/kgBW, and 900 mg/kgBW, along with indomethacin at 30 mg/kgBW. The results of the Mann-Whitney statistical test analysis showed a significant difference (p<0.05) between group K(-), which was administered only indomethacin, and group P2 and P3, which were administered extracts of water apple leaf at doses of 300 mg/kgBW and 900 mg/kgBW along with indomethacin at 30 mg/kgBW. There is an protective effect of water apple leaf extract (Syzygium aqueum) on gastric damage of male white rats (Rattus norvegicus) Wistar strain induced by indomethacin. Keywords: Water Apple Leaf, Syzygium Aqueum, Antioxidants, Indomethacin, Peptic Ulcer ABSTRAK Prevalensi ulkus peptikum yang disebabkan oleh penggunaan Nonsteroidal Anti-Inflammatory Drugs (NSAID) mengalami peningkatan dalam kurun waktu 10 tahun. Stres oksidatif yang disebabkan oleh NSAID dapat memicu terbentuknya ulkus peptikum. Tujuan penelitian ini untuk mengetahui efek protektif ekstrak daun jambu air (Syzygium aqueum) terhadap kerusakan lambung tikus putih jantan (Rattus norvegicus) galur wistar yang diinduksi indometasin. Penelitian eksperimental laboratorik dengan rancangan randomized post-test only control group ini menggunakan 24 tikus putih jantan galur Wistar yang dibagi ke dalam 6 kelompok. K(0) diberikan makan dan minum, K(-) diberikan indometasin 30 mg/kgBB, K(+) diberikan vitamin C 9 mg/kgBB dan indometasin 30 mg/kgBB, serta P1, P2, P3 diberikan ekstrak daun jambu air dengan dosis berturut-turut 100 mg/kgBB, 300 mg/kgBB, 900 mg/kgBB dan indometasin 30 mg/kgBB. Hasil analisis uji statistik Mann-Whitney didapatkan perbedaan bermakna (p<0.05) antara kelompok K(-) yang hanya diberikan indometasin dengan kelompok P2 dan P3 yang diberikan ekstrak 300 mg/kgBB dan 900 mg/kgBB serta indometasin 30 mg/kgBB. Ekstrak daun jambu air (Syzygium aqueum) memberikan efek protektif terhadap kerusakan lambung tikus putih (Rattus norvegicus) jantan galur Wistar yang diinduksi indometasin. Kata Kunci: Daun Jambu Air, Syzygium aqueum, Antioksidan, Indometasin, Ulkus Peptikum

Praktikalitas E-Modul: Sinergi Nilai Karakter dan Kearifan Lokal untuk Menguatkan Karakter Mahasiswa Menuju Era Society 5.0 Rahmadani, Ervi; K, Nurdin; Irfandi; Susianti, Susianti
Indo-MathEdu Intellectuals Journal Vol. 6 No. 5 (2025): Indo-MathEdu Intellectuals Journal
Publisher : Lembaga Intelektual Muda (LIM) Maluku

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54373/imeij.v6i5.3998

The purpose of this study was to examine the practicality of e-modules of Character Education Characterized by Local Wisdom. This research is follow-up research from previous research. This research is quantitative research using an instrument in the form of a practicality questionnaire totaling 15. The focus of the practicality test is the efficiency of the e-module, the benefits and ease of use. The data that has been obtained, then each is analyzed for each indicator in the form of a percentage, both from the responses of lecturers and students. Respondents consisted of students and lecturers totaling 106 people within the scope of the Faculty of Education and Teaching Training of the Islamic Education Management Study Program. The average response from lecturers was 90% which was included in the very practical category and the response from students was 83.5% which was included in the practical category. In addition, researchers also made improvements and several revisions for the convenience of users including adding images and layouts, until finally this e-module was completed in its development stage and could be used as teaching material in the lecture process in the Character Education course.

Pengaruh Model Pembelajaran Flipped Classroom Terhadap Keterampilan Berpikir Kritis Matematis Siswa Susianti, Susianti; Solihah, Fatimatus; Padli, Saiful
Tirai Edukasi : Jurnal Pendidikan Vol. 8 No. 1 (2025): Tirai Edukasi Juni 2025
Publisher : Universitas Qamarul Huda Badaruddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37824/zwjf8p10

This study aims to determine the effect of the flipped classroom learning model on junior high school students' mathematical critical thinking skills. The research employed a quantitative approach with a quasi-experimental design. The sample consisted of eighth-grade students divided into experimental and control groups. The research instrument was a mathematical critical thinking skills test based on interpretation, analysis, inference, and evaluation indicators. Data were collected through pre-test and post-test, then analyzed using the t-test. The results showed a significant difference in mathematical critical thinking skills between students taught using the flipped classroom model and those taught with conventional learning. The flipped classroom model positively influences students' mathematical critical thinking skills.

Efektivitas Pendekatan Contextual Teaching And Learning (CTL) Dalam Meningkatkan Kemampuan Berpikir Kreatif Siswa Susianti, Susianti; Rahmawati, Helmi; Solihah, Fatimatus
Tirai Edukasi : Jurnal Pendidikan Vol. 8 No. 1 (2025): Tirai Edukasi Juni 2025
Publisher : Universitas Qamarul Huda Badaruddin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37824/nx1bzv58

This study aims to investigate the effectiveness of the Contextual Teaching and Learning (CTL) approach in improving students’ creative thinking skills. This research employed a quasi-experimental design with a pre-test and post-test control group. The population consisted of all eighth-grade students of MTS Arrahmah NW Pringgarata in the 2024/2025 academic year. Samples were selected using purposive sampling, with class VIII A as the experimental group taught using CTL and class VIII B as the control group taught using conventional methods. The instrument used was a creative thinking test based on the indicators of fluency, flexibility, originality, and elaboration, which had been validated and proven reliable. Data were analyzed through normality, homogeneity, independent t-test, and N-Gain analysis. The findings revealed that the experimental group achieved a higher mean score (80.92) compared to the control group (66.12). The t-test showed a significance value < 0.001, indicating a significant difference between the two groups. Thus, CTL is effective in enhancing students’ creative thinking skills, particularly in learning Pythagorean Theorem.

Hubungan antara Ketersediaan Tutup Penampung Air dan Frekuensi Pengurangan Penampung Air dengan Kejadian Demam Berdarah Dengue Rianto, Muhamad Arif; Suharmanto, Suharmanto; Berawi, Khairun Nisa; Susianti, Susianti; Pramesona, Bayu Anggileo
Indonesian Journal of Nursing and Health Sciences Vol 6 No 2 (2025): Indonesian Journal of Nursing and Health Sciences: October 2025
Publisher : CV. Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijnhs.v6i2.7377

Demam Berdarah Dengue (DBD) merupakan masalah kesehatan masyarakat yang serius di Indonesia. Wilayah kerja Puskesmas Banjarsari Kota Metro mengalami peningkatan signifikan kasus DBD, dari 5 kasus pada tahun 2022 menjadi 87 kasus pada tahun 2024. Faktor lingkungan, khususnya ketersediaan tutup penampung air dan frekuensi pengurasan, diduga menjadi faktor risiko utama kejadian DBD. Tujuan penelitian ini untuk menganalisis hubungan antara ketersediaan tutup penampung air dan frekuensi pengurasan penampung air dengan kejadian Demam Berdarah Dengue di wilayah kerja Puskesmas Banjarsari Kota Metro tahun 2025. Penelitian ini menggunakan desain cross-sectional dengan pendekatan kuantitatif. Sampel penelitian berjumlah 389 responden yang dipilih menggunakan teknik proportionate stratified random sampling, terdiri dari 57 kasus positif DBD dan 332 kasus negatif DBD. Data dikumpulkan melalui kuesioner yang teruji validitas (nilai r berada pada rentang 0,467-0,786) dan reliabilitas nya (alpha Cronbach 0,97) dan observasi lapangan. Analisis data menggunakan uji chi-square. Hasil penelitian menunjukkan bahwa sebagian besar responden tidak memiliki tutup penampung air (47,8%) dan tidak melakukan pengurasan secara rutin (49,9%). Analisis bivariat menunjukkan terdapat hubungan signifikan antara ketersediaan tutup penampung air dengan kejadian DBD (p-value = 0,018; OR = 2,080; 95% CI = 1,165-3,715). Responden yang tidak memiliki tutup penampung air berisiko 2,080 kali lebih tinggi mengalami DBD. Terdapat hubungan signifikan antara frekuensi pengurasan penampung air dengan kejadian DBD (p-value = 0,043; OR = 1,888; 95% CI = 1,057-3,371). Responden yang tidak menguras penampung air minimal satu kali seminggu berisiko 1,888 kali lebih tinggi mengalami DBD. Ketersediaan tutup penampung air dan frekuensi pengurasan penampung air merupakan faktor risiko yang berhubungan signifikan dengan kejadian DBD di wilayah kerja Puskesmas Banjarsari Kota Metro. Diperlukan peningkatan kesadaran masyarakat melalui program promosi kesehatan dan intensifikasi pelaksanaan Pemberantasan Sarang Nyamuk (PSN) 4M Plus.

HUBUNGAN INFEKSI PARASIT USUS DENGAN STATUS GIZI ANAK SEKOLAH DASAR DI INDONESIA : SEBUAH TINJAUAN SISTEMATIS Hardiansyah, Ridwan; Mutiara, Hanna; Islami, Suryadi; Susianti, Susianti
Jurnal Kesehatan Tambusai Vol. 5 No. 4 (2024): DESEMBER 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v5i4.37832

Infeksi parasit usus merupakan salah satu masalah kesehatan yang signifikan di Indonesia, terutama di kalangan anak-anak sekolah dasar yang hidup di lingkungan dengan sanitasi dan kebersihan yang buruk. Studi ini bertujuan untuk mengevaluasi hubungan antara infeksi parasit usus dan status gizi anak sekolah dasar di Indonesia melalui tinjauan sistematis. Penelitian ini menggunakan pendekatan systematic review dengan panduan PRISMA. Proses penyaringan dilakukan dengan mengidentifikasi dan menganalisis artikel dari basis data elektronik yakni Google Scholar. Kata kunci yang digunakan mencakup kombinasi istilah-istilah berikut: "infeksi parasit usus," "status gizi," "anak sekolah dasar," dan "Indonesia", baik dalam bahasa Inggris maupun Indonesia, dengan penggunaan operator Boolean untuk meningkatkan sensitivitas pencarian Setelah proses penyaringan, artikel yang memenuhi kriteria inklusi dan eksklusi dilakukan penilaian bias menggunakan NOS adapted for cross-sectional studies. Seluruh artikel terpilih akan dilakukan analisis terhadap masing-masing hasil penelitian. Terdapat hubungan yang bervariasi antara infeksi parasit usus dan status gizi berdasarkan indikator Indeks Massa Tubuh (IMT), Berat Badan per Umur (BB/U), Tinggi Badan per Umur (TB/U), dan Berat Badan per Tinggi Badan (BB/TB). Beberapa studi menemukan hubungan signifikan, khususnya pada indikator TB/U dan IMT, sementara penelitian lain menunjukkan hasil yang tidak signifikan. Hubungan antara infeksi parasit usus dan status gizi anak sekolah dasar di Indonesia bersifat kompleks dan menunjukan hasil yang tidak konsisten pada setiap penelitian. Diperlukan penelitian lebih lanjut, terutama studi longitudinal, yang dapat mengevaluasi dampak jangka panjang infeksi parasit usus terhadap status gizi anak dengan mempertimbangkan faktor sosial, ekonomi, dan lingkungan.

Eksplorasi Imunoterapi dan Terapi Gen dalam Pengobatan Tumor Otak: Literature Review Hana Muthi'a Putri; Windarti, Indri; Mayasari, Diana; Susianti, Susianti
Medula Vol 14 No 12 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i12.1378

Brain tumors are a significant neurological disorder with a high mortality rate, especially in cases of glioblastoma, which is highly aggressive and difficult to treat. Conventional treatment methods, such as surgery, radiation therapy, and chemotherapy, are often not effective enough, particularly in advanced stages. This study aims to explore two innovative approaches, namely immunotherapy and gene therapy, as alternative treatments for brain tumors. Immunotherapy works by enhancing the immune system's ability to fight cancer cells through methods such as checkpoint inhibitors, cancer vaccines, and CAR-T therapy. However, the success of immunotherapy is often hindered by the blood-brain barrier (BBB), which limits the delivery of therapy to the brain. On the other hand, gene therapy offers a solution by modifying genetic material, either to repair damaged genes or to directly destroy cancer cells. Approaches such as the use of oncolytic viruses, CRISPR technology, and nanoparticles have shown promising results in preclinical research and early clinical trials, particularly for glioblastoma. The combination of immunotherapy and gene therapy opens new opportunities to enhance treatment effectiveness by strengthening the immune response and targeting tumors more specifically. However, challenges remain, including treatment resistance, side effects, and limitations in brain delivery methods. Further research is needed to ensure the safety, efficacy, and widespread application of this combination therapy. Immunotherapy and gene therapy have great potential as breakthroughs in the future treatment of brain tumors. Relevant literature, including articles and journals from both national and international sources, were gathered through online searches in various databases, such as Google Scholar, PubMed, and NCBI, and used to compile this article.

Co-Authors Ace Tatang Hidayat Agustyas Tjiptaningrum Ajabar, Ajabar Akram, Musfira Azizah Ambarwati, Yuli Anggraeni Janar Wulan, Anggraeni Janar Arfah, Arfah Ayu Irawati Azis, Sukmawati Bahri. S, Andi Bayu Anggileo Pramesona Betta Kurniawan, Betta Buana, Faris Agung DAMIRAH DAMIRAH, DAMIRAH Djamir, A. Fatimah Dyah Wulan Sumekar Rengganis Wardani Endro Prasetyo Wahono Ety Apriliana Eva Lusina, Septia Evi Kurniawati, Evi Faisal Rahman, Faisal Fatriyadi Suwandi, Jhons Fausyiah, Nurul Febrianti, Arlin Fitria Saftarina Gemayangsura, Gemayangsura Giska Tri Putri Hana Muthi'a Putri Hanif Kurniadi Hanna Mutiara, Hanna Happy, Terza Aflika Hardiansyah, Ridwan Haryono, Iranita Hasbilla, Raihan Fathurrahman Helmi Rahmawati Hendri Busman Herlina Herlina Imron, Nadi Indri Windarti Intan Kusumaningtyas Intanri Kurniati Iranita Haryono Irfandi Ismunanto, Aziza Regina Kinasih Iswandi Darwis Jamir, Fatimah Janar Wulan, Anggraini Jausal, Anisa Nuraisa Jhons Fatriyadi Suwandi Joni, Agnesia Priskila Justisia, Adilla Khairun Nisa Landoni, Fira M. Ridho Ulya Mansur, Narti Marcellia, Selvi Marhani Marhani Mayasari, Diana Muhamad Stiadi Novianty, Detty Nurdin K, Nurdin Oktadoni Saputra, Oktadoni Oktaviani, Indri Ovalia, Nora Wilya Padli, Saiful Rahmadani, Ervi Ramadhana Komala Rasmi Zakiah Oktarlina Ratna, Maya Ganda Reni Zuraida Rianto, Muhamad Arif Risti Graharti Rizki Hanriko Rodiani, Rodiani Ronny Lesmana Rosdiana Rosdiana Rudianto, Waluyo Rudiyanto, Waluyo Rurini Retnowati Ruslani, Nada Oktista Safriansyah, Wahyu Salam, Supriyanto Sandra Amalia Riyadi Septia Eva Lusina Septiani, Linda Solihah, Fatimatus Soraya, Yeni Suharmanto Surriandari, Latifah Dwi Suryadi Islami Sutarto Sutarto Sutyarso Sutyarso Syahdewa, Budi Indra Syahriyah Semaun, Syahriyah SYAIFUL BAHRI Syazili Mustofa Tri Umiana Soleha Tuasikal, Moh. Irfan Tutik Ernawati Unang Supratman Usman, Arifa W, Dyah Wulan Sumekar R. W., Dyah Wulan Sumekar R. Wardani, Dyah Wulan Wati, Imelda Fera Yudho Prabowo, Arif Zahra, Aulia Jannatuz

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