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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Mutiara Medika: Jurnal Kedokteran dan Kesehatan Biomedika Universa Medicina Jurnal Surya Medika Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) JURNAL EDUCATION AND DEVELOPMENT Amerta Nutrition Jurnal Medika Malahayati Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Jurnal Biomedika dan Kesehatan Jurnal Kedokteran Universitas Palangka Raya JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Inisiasi Jurnal Inovasi Pengabdian dan Pemberdayaan Masyarakat Jurnal Kedokteran Hewan Biomedika Berkala Ilmiah Kedokteran dan Kesehatan Masyarakat JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia
Miranti Dewi Pramaningtyas
Department Of Physiology, Faculty Of Medicine, Universitas Islam Indonesia, Yogyakarta, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Relationship of History of Hypertension with Severity and Onset of Preeclampsia: A Cross-Sectional Study Adnan, Muhammad Luthfi; Weningtyas, Vyanda Sri; Pramaningtyas, Miranti Dewi; Wahyana, Eka Budi
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 3 July 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i3.2168

Abstract

Objective: This study aimed to find correlation between a history of hypertension with severity and onset of preeclampsia.Methods: A retrospective cohort study with retrospective analysis of medical record data in patients with preeclampsia and severe preeclampsia from November 2021 – February 2022 was conducted at dr. Soediran Mangun Sumarso Regional General Public Hospital, Wonogiri, Central Java. Analysis was performed between the history of hypertension with severity and onset (<34 weeks and age ? 34 weeks gestational age). Data analysis was performed using SPSS software with univariate Chi-Square analysis.Results: A total of 44 medical record data were obtained in this study. A total of 20 patients (45.5%) had a history of hypertension and 24 (55.5%) patients had no history of hypertension. A total of 23 patients (52.3%) were diagnosed with severe preeclampsia and 21 patients (47.7%) were diagnosed with preeclampsia. Based on statistical analysis, it was found that there was no significant correlation between the history of hypertension and the severity of preeclampsia (p=0.741; OR (CI 95%): 0,818 (0,249 – 2,690)) and onset (p=0.88; OR (CI 95%): 1,133 (0,222 – 5,788)).Conclusion: There is no relationship between history of hypertension with the severity and onset of preeclampsia. Further studies with larger populations are needed to analyze the relationship between history of hypertension and preeclampsia.Keywords: blood pressure, cardiovascular disease, hypertension, onset, preeclampsia.
Pengaruh Minuman Sinbiotik dari Susu Kefir dan Konsentrat Bengkuang (Pachyrhizus erosus) terhadap Kadar Malondialdehid Jaringan Usus Tikus Hiperlipidemia Aprillia, Viola; Utami, Rizki Fajar; Pramaningtyas, Miranti Dewi
Jurnal Biomedika dan Kesehatan Vol 7 No 3 (2024)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2024.v7.304-311

Abstract

Background Intestinal tissue damage is one of the effects of increased reactive oxygen species (ROS) in hyperlipidemia. Cells damaged by hyperlipidemia experience changes in the biomarker malondialdehyde (MDA). The use of jicama extract and kefir alone has shown the ability to lower cholesterol levels. This study aims to determine the effect of the combination of jicama extract and kefir milk as a synbiotic drink on MDA levels in the intestines of hyperlipidemic rats. Methods Twenty-five male Wistar rats were divided into 5 groups, consisting of negative control (K-) and positive control (K+) groups and three treatment groups (P1, P2, P3). Hyperlipid induction using quail egg yolk. The dose of quail egg yolk was 5ml/200grBW. The intervention group was given a synbiotic drink with a dose of 5ml/200grBW with 3 types of kefir milk and jicama extract combination formulations. Intestinal MDA levels were measured after termination and the data were analyzed using statistical software. Results The level of MDA in intestine (nmol/ml) were 11.78±0.21 (K+), 0.73±0.05 (K-), 5.38±0.28 (P1), 3.02±0.14 (P2), 1.59±0.11 (P3). The analysis of the results of the MDA level showed significant differences in all groups after being given synbiotic drinks (p <0.001). Conclusions Combination of jicama extract and kefir as synbiotic drinks significantly affect the intestinal MDA levels of hyperlipidemic rats.
EFFECT OF CIPLUKAN STEMS AND LEAVES EXTRACT ADMINISTRATION (Physalis angulata L.) ON THE DEGREE OF hepatic lobes INFLAMMATION IN DYSLIPIDEMIA INDUCED WISTAR RATS Safira, Nazala; Pamungkas, Katon; Utami, Rizki fajar; Ahsani, Dwi Nur; Pramaningtyas, Miranti Dewi
Jurnal Kedokteran Hewan Vol 18, No 1 (2024): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v18i1.32339

Abstract

The aim of this study was to determine the effect of stems and leaves ciplukan extract on the degree of liver lobe inflammation in dyslipidemia-induced wistar rats. This research was an experimental study with a post-test only design. A total of 24 Wistar rats were allotted into 4 groups with 6 rats per group. Hepatic organs were then histologically stained with Hematoxylin-Eosin stain. Inflammation reading was done by looking for inflammatory foci in the preparation. The result was then analyzed using Kruskal-Wallis test. The results showed that groups I and II had one severe inflammation. Group III had two severe degrees of inflammation. Group IV had no severe inflammation. The analysis revealed that there was no significant difference in the degree of inflammation between groups (P= 0.964). Administration of ciplukan stem and leaf extract did not affect the degree of liver lobe inflammation in Wistar rats induced by dyslipidemia.
Faktor Maternal dan Kadar Lemak Dalam Air Susu Ibu (ASI): Sebuah Tinjauan Pustaka Wahdiyati, Siti; Utami, Rizki Fajar; Pramaningtyas, Miranti Dewi
Berkala Ilmiah Kedokteran dan Kesehatan Masyarakat Vol. 2 No. 1 (2024)
Publisher : Fakultas Kedokteran, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/bikkm.vol2.iss1.art10

Abstract

Latar Belakang: Air susu ibu (ASI) memiliki komponen makronutrien dan mikronutrien yang penting bagi bayi. Salah satu komponen makronutrien penting adalah lemak dalam ASI. Kandungan lemak ASI dipengaruhi oleh beberapa faktor. Salah satu factor yang diduga mempengaruhi kadar lemak dalam ASI adalah kadar lemak total ibu. Tujuan: Tujuan dari penelitian ini adalah untuk mengetahui hubungan antara komponen lemak ibu dengan lemak dalam ASI. Metode: Tinjauan pustaka dilakukan dari beberapa jurnal yang terbit mulai tahun 2010 - 2023. Pencarian dilakukan dengan kata kunci: breastfeeding, fat, dan maternal body mass index. Sumber dari penelitian kepustakaan ini terdiri dari kriteria inklusi, diantaranya bayi lahir cukup bulan, berat lahir cukup, menyusui eksklusif, dan bayi sehat dan normal. Hasil: Lemak merupakan salah satu komponen penting dalam ASI. Komposisi lemak tubuh ibu memiliki hubungan terhadap kadar lemak ASI. Faktor maternal juga mempengaruhi kandungan lemak ASI yang berkaitan dengan hormon maternal dengan lemak ASI. Hubungan ini dapat mempengaruhi proses pertumbuhan dan perkembangan bayi. Simpulan: Komponen lemak ibu memiliki hubungan terhadap kadar lemak dalam ASI yang dipengaruhi berbagai faktor. Penelitian lebih lanjut diperlukan untuk menilai fungsi dan pengaruh komponen lemak terhadap tumbuh kembang bayi. Kata Kunci: ASI, faktor maternal, menyusui, lemak
Hubungan Aktivitas Fisik Terhadap Risiko Terjadinya Sindroma Metabolik Pada Pegawai Kantor PT. PLN Unit Pelaksana Pelayanan Pelanggan (UP3) Daerah Istimewa Yogyakarta Al-Ghozi, Yasfi Suryalfihro Al-Ghozi; Sukarno, Rizky Triutami; Nugraha, Zainuri Sabta; Pramaningtyas, Miranti Dewi
Berkala Ilmiah Kedokteran dan Kesehatan Masyarakat Vol. 2 No. 2 (2024)
Publisher : Fakultas Kedokteran, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/bikkm.vol2.iss2.art6

Abstract

Latar Belakang: Sindrom Metabolik (SM) dan kurang aktivitas fisik memiliki prevalensi cukup tinggi di Indonesia, termasuk di wilayah perkantoran Daerah Istimewa Yogyakarta (DIY). SM merupakan sekelompok gangguan metabolisme, sedangkan kurang aktivitas fisik merupakan kondisi seseorang kurang melakukan aktivitas fisik. Kondisi kurangnya aktivitas fisik dapat berisiko untuk terjadinya sindrom metabolik. Tujuan: Mengetahui hubungan Aktivitas Fisik Terhadap Risiko Terjadinya Sindroma Metabolik pada Pegawai Kantor PT. PLN Unit Pelaksana Pelayanan Pelanggan (UP3) Daerah Istimewa Yogyakarta. Metode: Penelitian ini merupakan penelitian kuantitatif observasional dengan desain cross sectional. Sampel pada penelitian ini menggunakan purposive sampling dengan perhitungan uji hipotesis dua proporsi didapatkan sebanyak 49 sampel untuk desain penelitian cross sectional. Pengambilan data didapatkan dari Medical Check up dan pengisian kuisioner Bouchard di Unit Pelaksana Pelayanan Pelanggan (UP3) PLN Yogyakarta. Hasil: Hasil uji chi-square untuk variabel aktivitas fisik menunjukkan nilai p-value sebesar 0,915, yang berarti bahwa p>0,05. Dengan demikian, dapat disimpulkan bahwa tidak terdapat hubungan yang signifikan pada variabel aktivitas fisik. Namun didapatkan pada variabel jenis kelamin nilai p-value sebesar 0,000 yang artinya p<0,05 sehingga hasil signifikan. Sebaliknya, pada variabel umur, nilai p-value sebesar 0,136, yang berarti p>0,05, mengindikasikan bahwa tidak terdapat hubungan yang signifikan pada variabel umur. Simpulan: Tidak terdapat hubungan bermakna antara tingkat aktivitas fisik dengan risiko terjadinya sindrom metabolik pada Pegawai Kantor PT. PLN Unit Pelaksana Pelayanan Pelanggan (UP3) Daerah Istimewa Yogyakarta.
Co-Authors Adi Nugraha Adnan, Muhammad Luthfi Adyaksa, Dewa Nyoman Murti Al-Ghozi, Yasfi Suryalfihro Al-Ghozi Aprillia, Viola Budiastuti, Ernadita Dewanti, Alfi Brillianti Chrisna Dewanti, Anggita Dini Islamiana Dwi Nur Ahsani Dwi Nurwulan Pravitasari Emi Azmi Choironi Ety Sari Handayani Fadilatul Khusna Amalla Firdaus, Hana Afifah Firdaus, Lidya Sabilla Fitriati, Yasmini Hana Isnaini Al Husna Hasibuan, Diah Hydrawati Sari Hilmi Ardian Sudarto Kaka Citta Prasiddha Kholifa Nur Ardhina Kiasati, Aghnia Lusiantari, Rokhima Mohamad Alif Ramadan Mohamad Alif Ramadan Muhammad Luthfi Muhammad Luthfi Adnan Nurani, Mega Puspa Nurmasitoh, Titis Pamungkas, Katon Pattimura, Rachmi Hidayati Putri, Fara Amalia Putri, Merisa Dinda Rahmawati, Isna Arifah Ratna Wulandari Reza Ishak Estiko RIZKI FAJAR UTAMI Safira, Nazala Safitri, Amalia Adityas Dyah Sukarno, Rizky Triutami Wahdiyati, Siti Wahyana, Eka Budi Wantoputri, Noviani Ima Weningtyas, Vyanda Sri Widyaningsih, Niken Wijaya, Diani Puspa Yanasta Yudo Pratama Zainuri Sabta Nugraha, Zainuri Sabta