Article Per Year (5 Year)
p-Index From 2020 - 2025
4.033
P-Index
This Author published in this journals
All Journal VALENSI Science and Technology Indonesia ALCHEMY Jurnal Penelitian Kimia JURNAL PENDIDIKAN TAMBUSAI Journal of Midwifery and Nursing Jurnal Penelitian Farmasi dan Herbal JURNAL INOVASI KESEHTAN MASYARAKAT Jurnal Farmanesia Jurnal Pengabdian Masyarakat Putri Hijau Jurnal Pengabdian Masyarakat Tjut Nyak Dhien Jurnal Natural Jurnal Kedokteran Hewan Herbal Medicine Journal Journal of Pharmaceutical and Sciences. Molekul: Jurnal Ilmiah Kimia
Nerdy, Nerdy
Universitas Tjut Nyak Dhien
Religion Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Education Energy Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary

Published : 34 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Journal of Pharmaceutical and Sciences.

 1 
Formulasi dan Evaluasi Tablet dengan Bahan Tambahan Tongkol Jagung (Zea mays L.) sebagai pengganti HPMC yang digunakan untuk Anti Diabetes Surbakti, Christica Ilsanna; Suryani , Monica; Nerdy, Nerdy
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.779

Abstract

Corn (Zea mays L) is a food crop that is known and cultivated in developing countries. So far, corn cobs have not been widely used as a value-added product. Corn cobs have 35.5% crude fiber, 2.5% protein, 0.12% calcium, 0.04% phosphorus and the remaining 38.16% of other substances. Corn cobs, which are biomass, contain phenolic phytochemicals which are very likely to be used as active antioxidant ingredients. The choice of method for making tablets is adjusted to the characteristics of the active substance used. In this research, the method used in making metformin HCl tablets was wet granulation. Wet granulation is the process of adding liquid to a powder or powder mixture in a container equipped with stirring which will produce agglomeration or granules. The evaluation results of corn cob additive granules as a substitute for HPMC showed the results of the flow time test (F1 1.5 seconds, F2 1.4 seconds F3 1.63 seconds), F1 angle of repose test (34.96 o, F2 41, 43 o, F3 41.92 o), humidity test (F1 1.794 %, F2 1.999 %, F3 2.331 %) and compressibility test (F1 11 %, F2 15%, F3 8%).  The results of the evaluation of antalgin tablets using corn cobs as a substitute for HPMC showed visual test results where the tablets were round and white in color, the weight uniformity test showed results (F1 A (5%) 708.7-783.3 and column B (10% ) 671.4-820.6, F2 A (5%) 562.775– 705.75 and column B (10%) 571.05-698.6, F3 688.75– 761.25 and column B (10%) 625.5-797.5), size uniformity test shows results (F1 diameter 1.3545 and thickness 0.4705, F2 diameter 1.359 and thickness 0.468, F3 diameter 1.36 and thickness 0.471), fragility test shows results (F1 0 .06978367 %, F2 0.53272451 %, F3 0.06978367 %) and tablet hardness showed results (F1 6.764, F2 4.984, F3 7.89) and disintegration time test showed results (F1 2 minutes, F2 2 minutes, F3 2 minute).
Co-Authors Abdi Wira Septama Ariani, Peny Atika Mulyati Bahtera Bin David Purba BAKRI, TEDY KURNIAWAN Barus, Bunga Rimta Bunga Mari Sembiring Bunga Rimta Barus CHRISTICA ILSANNA SURBAKTI Christivo Tambusai Dachi, Kanne Dhita Millenia Br. Tarigan Dian Ika Perbina Meliala Effendy De Lux Putra, Effendy De Lux Elysa Elysa Evalina Manurung Faisal Yusuf Faisal, Yusuf Febia, Ananda Dwina Ferry Handika Firdaus Fahdi Firdaus, Fahdi Fitri, Rizka Ramadhani Fujiko, Muflihah GINTING, SELAMAT Hulu, Titi Kurniawati Ika Julianti Tambunan JIHAN SAFIRA Kanne Dachi Kesaktian Manurung Linda Margata Linda Margata Linda Margatha Linta Meliala Linta Meliala Manurung, Kesaktian MAYA KUSUMA Meliala, Linta Mierza, Vriezka Muflihah Fujiko Muflihah Fujiko Muharni Saputri Nadia, Syarifah NILSYA FEBRIKA ZEBUA Nilsya Febrika Zebua, Nilsya Febrika Ningrum, Adelia Puspita Retno Ningrum, Siti Rahmi Nurfazillah, Nurfazillah Nurul karima Oppie Meisya Tanjung Palas Tarigan Pravil Mistriyanto PUJI LESTARI Puji Lestari Puji Lestari Puji, Lestari RANI FARAH BUTSAINAH TANJUNG Razali Razali Razali, Mariany Refi Bahrainur Rifoni Simbolon Rusdi Andreas Sembiring Saiful Batubara SATRIYAS ILYAS Selamat Ginting Siagian, Nurul Siagian, Nurul Aini Silmi Hayati Siti Nurmalisa Siti Rahmi Ningrum Sitohang, Nikasia Gabriela Supran Hidayat SURBAKTI, CHRISTICA ILSANNA Suryani , Monica Syarifah Nadia Tandra Alexandro Tedy Kurniawan Bakri Tedy Kurniawan Bakri Tedy Kurniawan Bakri Tedy Kurniawan Bakri TJUT XENA Virda Widya Pratiwi Vivi Sofia Vonna Aulianshah Vriezka Mierza Zuhairiah Nasution, Zuhairiah