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PERAN ANTIHISTAMIN DALAM DERMATOLOGI: TINJAUAN FARMAKOLOGI, EFIKASI KLINIS, DAN KEAMANAN PADA KEHAMILAN Yosserizal, Yosserizal; Anggi Syafitri Nasution; Arientina Amanda Filia; Vioni Yolisa Fitri; Muhammad Zaky; Abdullah, Dessy
Nusantara Hasana Journal Vol. 5 No. 1 (2025): Nusantara Hasana Journal, June 2025
Publisher : Yayasan Nusantara Hasana Berdikari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59003/nhj.v5i1.1675

Abstract

Antihistamines are widely used as first-line therapy for allergic skin disorders such as urticaria, dermatitis, and pruritus. Understanding their pharmacological mechanisms, classification, and safety profiles is essential for effective clinical application, particularly for long-term use and during pregnancy. This article is a narrative review based on scientific literature from national and international databases (PubMed, Scopus, SINTA), focusing on pharmacology, classification, clinical indications, contraindications, adverse effects, and safety of antihistamines in pregnancy. Antihistamines act as inverse agonists at histamine receptors, primarily H1 and H2. First-generation agents are lipophilic, crossing the blood–brain barrier and causing sedation, while second-generation antihistamines act selectively on peripheral receptors with fewer central nervous system side effects. During pregnancy, cetirizine and loratadine are recommended due to favorable safety profiles compared to first-generation drugs. In dermatology, antihistamines are effective in managing urticaria, angioedema, lichen simplex chronicus, mastocytosis, and various allergic skin conditions. The selection of antihistamines should be guided by pharmacokinetics, side effect profile, patient-specific conditions, and pregnancy safety. Second-generation antihistamines are generally preferred for long-term management owing to their efficacy and reduced central nervous system risk.
Tinjauan Kriminologi dalam Praktik Pemerasan oleh Oknum Anggota Organisasi Masyarakat dengan Dalih Pengamanan Lingkungan Ryan Rafi Aziz; Muhammad Zaky
Reslaj: Religion Education Social Laa Roiba Journal Vol. 7 No. 9 (2025): RESLAJ: Religion Education Social Laa Roiba Journal
Publisher : Intitut Agama Islam Nasional Laa Roiba Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47467/reslaj.v7i9.9003

Abstract

The occurrence of extortion by individuals associated with community organizations (Ormas) under the guise of neighborhood security in the Pamulang area signifies a departure from the optimal function of Ormas as social agents within the community. This approach engenders dread and discomfort while also underscoring the disparity between legal standards and social reality. This study intends to examine extortion activities through a criminological perspective, specifically utilizing Edwin Sutherland’s Differential Association Theory, and to assess the efficacy of current legal frameworks. The study employs a qualitative research methodology, utilizing in-depth interviews and observations to examine the experiences and viewpoints of both perpetrators and victims, thereby elucidating the formation and perpetuation of deviant conduct within Ormas contexts. The research inquiries examine the role of social learning processes in extortion and the efficacy of existing legal frameworks in resolving this issue. The results demonstrate that criminal behavior in Ormas is acquired through profound social contact, heavily influenced by the frequency, duration, priority, and strength of group relationships. Moreover, inadequate legal penalties, minimal public reporting, and a lack of stringent control of Ormas operations intensify the persistence of these practices. This study advocates for the enhancement of law enforcement, the amendment of Ormas regulations to incorporate more rigorous criminal penalties, and the elevation of public legal literacy to motivate persons to report and counter intimidation.
"IMPLEMENTATION OF CRIME PREVENTION THROUGH ENVIRONMENTAL DESIGN IN MELIA RESIDENCE HOUSING, SOUTH TANGERANG" Reyhan Taufiq Ramadhan; Muhammad Zaky
Multidiciplinary Output Research For Actual and International Issue (MORFAI) Vol. 5 No. 6 (2025): Multidiciplinary Output Research For Actual and International Issue
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/morfai.v5i6.3374

Abstract

Residential areas have begun to implement a security system using a one-gate system and strict patrols. These facilities are supported by guards or security personnel to ensure the safety of the residential area. This research is expected to contribute to the development of studies in the field of criminology, especially related to the application of the Crime Prevention Through Environmental Design (CPTED) approach. The author acknowledges that by using a descriptive qualitative research type, it is possible to find out how crime prevention strategies and the implementation of CPTED are implemented as an effort to prevent crime in the Residential Areas. Qualitative research itself also allows researchers to conduct direct interviews with sources who will help in collecting data on the issues being researched. This research is related to Ronald V Clarke's Situational Crime Prevention (SCP) Theory, where Situational Crime Prevention and CPTED can complement each other to prevent crime in Residential Area. This theory aims to explain the application of CPTED as a Crime Prevention Strategy so that criminal acts become more difficult to commit. The results of this study can be used as evaluation material and consideration in designing housing environment infrastructure to be safer through CPTED principles.
PERAN GURU NGAJI DALAM MENINGKATKAN PEMAHAMAN AGAMA ISLAM BAGI ANAK-ANAK DI LINGKUNGAN MASYARAKAT Muhammad Zaky; Vikri fauzan; Azmy Ali Muchtar; Dzaliva Alfatir; Nasywa Nabilah
Ilma Jurnal Pendidikan Islam Vol. 2 No. 2 (2024): Jurnal ILMA
Publisher : Fakultas Agama Islam Universitas Islam Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58569/ilma.v2i2.1360

Abstract

Peran guru ngaji di tengah-tengah masyarakat sangatlah susah karana pemahaman dari masyarakat awwam itu sangat–sangat mendasar sekali untuk mengetahui nilai-nilai agama jadi dikatakan sangatlah berat, sangatlah sulit. Tetapi akan begitu, peran-peran guru ngaji yang istiqomah terus karena Allah swt., dan hanya mengharap ridho Allah swt., tidak hanya dari praktek fisiknya saja tapi mereka yang istiqomah meminta kepada Allah swt., agar di lembutkan hatinya untuk menerima ajaran Allah swt., dan Nabi Muhammad saw langsung terjun ke masyarakat contoh salah satu nya tadi belum tentu yang islam melaksanakan sholat 5 waktu. Menurut salah satu pengajar disana Guru ngaji juga berperan penting dalam membentuk karakter anak-anak. Mereka mengajarkan nilai-nilai Islam yang luhur, seperti kejujuran, amanah, toleransi, dan kasih sayang. Nilai-nilai ini dapat membantu anak-anak menjadi pribadi yang baik dan bermanfaat bagi masyarakat. Tujuan penelitian ini adalah agar bisa mengetahui seberapa penting nya peran guru ngaji di lingkungan sekitar, dan mengetahui metode-metode kualitatif deskriptif yang di ajarkan kepada para santri majelis Azzikrannafi’ah. Dan hasil penelitian mengungkapkan bahwa peran guru ngaji di dalam Masyarakat itu sangat penting dan sangat di butuh kan, di tambah di era milenial yang serba canggih. Jadi, anak-anak zaman ini lebih senang dengan pengetahuan yang bagaimanapun, namun harus dengan penyampaian yang menarik bagi si anak itu.