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The Correlation between Blood Lead (Pb) Levels and Total Leukocyte Count among Silver Man Individuals Fauziah Rahmah; Kurnia Ritma Dhanti; Retno Sulistiyowati; Dina Ratna Juwita
Indonesian Journal of Global Health Research Vol. 8 No. 4 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i4.1674

Abstract

Lead (Pb) exposure remains an environmental health problem that affects groups with direct exposure, including silver man individuals who coat their bodies with paint. Lead is still found in various paint products due to its use as a pigment and additive, making it a potential major source of environmental lead exposure. Lead is known to affect the immune system through inflammatory mechanisms and oxidative stress, which may result in alterations in total leukocyte count. This study aimed to determine the association between blood lead (Pb) levels and total leukocyte count among silver man individuals. This study employed an analytic observational design with a cross-sectional approach involving 18 silver man individuals who were recruited using an accidental sampling technique among individuals who met the inclusion criteria. Blood Pb levels were measured using Atomic Absorption Spectrophotometry (AAS), while total leukocyte counts were analyzed using a hematology analyzer. The relationship between blood Pb levels and total leukocyte count was assessed using Pearsons correlation test. The results showed that all subjects had elevated blood Pb levels. Statistical analysis indicated no significant association between blood Pb levels and total leukocyte count, with a p-value of 0.420 (p 0.05) and a correlation coefficient (r) of 0.202, indicating a positive but very weak correlation. There was no significant association between blood lead (Pb) levels and total leukocyte count among silver man individuals. These findings highlight the importance of vigilance regarding lead exposure and the need for regular health monitoring among at-risk populations.  
The Correlation Between Frequency of Mineral Water Consumption, Coffee, Length of Employment with Serum Creatinine Levels and Estimated Glomerular Filtration Rate among Brick Craftsmen Tuflayfah Khasanah; Defi Nurul Hayati; Retno Sulistiyowati; Kurnia Ritma Dhanti; Minto Rahaju
Indonesian Journal of Global Health Research Vol. 8 No. 4 (2026): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v8i4.2100

Abstract

Chronic Kidney Disease (CKD) leads to a decline in renal function, thereby affecting fluid and electrolyte balance in the body. Risk factors for CKD include advanced age, chronic diseases, kidney disorders, unhealthy lifestyles, and adverse environmental conditions. Prolonged exposure to extreme heat, combined with unhealthy lifestyle behaviors such as inadequate water intake and frequent consumption of caffeinated beverages, may lead to dehydration. Prolonged dehydration can reduce extracellular fluid volume, leading to impaired kidney function. This study aimed to analyze the correlations between the frequency of coffee consumption, water intake, and length of employment with serum creatinine levels and estimated glomerular filtration rate (eGFR) among brick craftsmen in Sokaraja Sub-District, Banyumas. The study employed a cross-sectional design involving 23 respondents selected using accidental sampling. Data analysis was conducted using Spearman and Pearson correlation tests at the 95% confidence level, and a multivariate analysis was performed with multiple linear regression. The bivariate analysis showed significant correlations between coffee consumption, water intake, and work duration and serum creatinine levels and eGFR values (p < 0.05). However, age and length of employment were not statistically significantly associated in the bivariate analysis (p > 0.05). Multivariate analysis indicated that water intake had a significant effect on serum creatinine and eGFR, although this effect was influenced by respondents' age. An increase in coffee consumption was associated with elevated creatinine levels and reduced estimated glomerular filtration rate (eGFR). Inadequate water intake results in dehydration, thereby impairing renal function in the elimination of metabolic waste. Prolonged working hours in hot environments increase the risk of oxidative stress and renal tubule injury.
Association Between Procalcitonin and Lymphocyte Counts Post-Cupping Therapy in Patients With Diabetes Mellitus Nadia Rizqi Aulia; Dita Pratiwi Kusuma Wardani; Uli Mas’uliyah Indarwati; Arif Mulyanto; Kurnia Ritma Dhanti
Journal of Education Technology Information Social Sciences and Health Vol. 5 No. 2 (2026): September 2026
Publisher : CV. Rayyan Dwi Bharata

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57235/jetish.v5i2.9060

Abstract

Diabetes mellitus (DM) is a long-term metabolic condition that arises when the pancreas fails to produce insulin properly, typically marked by blood glucose readings above the normal threshold of 200 mg/dL. This condition activates an inflammatory response within the body, and procalcitonin is among the biomarkers used to detect such inflammation in DM patients. Beyond this marker, hematological parameters, particularly lymphocyte counts, can also serve as useful indicators. Persistent hyperglycemia experienced by DM patients can give rise to systemic inflammation, which in turn alters both the quantity and function of lymphocytes. Cupping therapy is believed to help improve blood circulation and reduce blood glucose levels in patients with DM. This study aimed to determine the correlation between procalcitonin levels and lymphocyte counts in patients with DM after undergoing cupping therapy. This study employed q quasi-experimental method with a one-group posttest-only design. The study involved 22 patients with type 2 diabetes melitus who underwent wet cupping therapy at Griya Bekam Lebah Emas Banyumas. Procaltionin levels and lymphocyte counts were analyzed using the Spearman Rho correlation test. The result of the Spearman Rho correlation test showed a p-velue of 0.257 and an r-value of 0.253. Based on these results, no significant correlation was found between procalcitonin levels and lymphocyte counts in DM patients post cupping therapy.
Korelasi nilai rasio neutofil-limfosit dengan kadar ureum dan kreatinin pada pasien hemodialisa rutin di RSU Wiradadi Husada Kintan Yaumi Lailatil Qodri; Retno Sulistiyowati; Umi Solikhah; Kurnia Ritma Dhanti
JOURNAL OF Community Health Issues Vol. 3 No. 3 (2026): August Edition 2026
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR) Kerjasama dengan Ikatan Perawat Kesehatan Komunitas Indonesia (IPKKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/chi.v3i3.4088

Abstract

Background: Chronic kidney disease is characterized by a progressive and irreversible decline in kidney function, which may require hemodialysis therapy at an advanced stage. Patients undergoing routine hemodialysis are at risk of chronic inflammation, which can be reflected by the Neutrophil-to-Lymphocyte Ratio (NLR), while urea and creatinine levels can indicate the accumulation of metabolic waste products in the body. Purpose: To determine the correlation between NLR and urea and creatinine levels in patients undergoing routine hemodialysis at RSU Wiradadi Husada. Method: This study used an analytical observational design with a cross-sectional approach and consecutive sampling technique. A total of 42 patients undergoing routine hemodialysis were examined in June 2026. NLR values were obtained from complete blood count results, while urea and creatinine levels were obtained from serum examinations. Data were analyzed using the Spearman correlation test. Results: The results showed no significant correlation between NLR and urea levels (r = 0.054; p = 0.736) or between NLR and creatinine levels (r = −0.189; p = 0.230). Conclusion: There was no significant correlation between NLR and urea or creatinine levels in patients undergoing routine hemodialysis at RSU Wiradadi Husada.