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All Journal Bulletin of Chemical Reaction Engineering & Catalysis AGRIVITA, Journal of Agricultural Science IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) JPSriwijaya Science and Technology Indonesia Jurnal Penelitian Sains Indonesian Journal of Chemistry JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Kreativitas PKM Molekul: Jurnal Ilmiah Kimia Jurnal Abdi Insani Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat BIOVALENTIA: Biological Research Journal Jurnal Pepadu Bulletin of Chemical Reaction Engineering & Catalysis
Ferlinahayati Ferlinahayati
Department Of Chemistry, Faculty Of Mathematics And Natural Sciences, University Of Sriwijaya, Jl. Raya Palembang Prabumulih Km 32, Ogan Ilir, South Sumatera 30622
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences

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Steroid Compounds From Gynura pseudochina (Lour) DC Ferlinahayati Ferlinahayati; Roby Pahala J Gultom; Herlina Herlina; Eliza Eliza
Molekul Vol 12, No 1 (2017)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (527.614 KB) | DOI: 10.20884/1.jm.2017.12.1.293

Abstract

Daun dewa (Gynura pseudochina Lour DC) is a one of popular traditional medicine to treat various diseases. This research was conducted to isolate chemical compounds from daun dewa leaves using various chromatographic techniques. A steroid mixture namely b-sitosterol (1a) and stigmasterol (1b) were isolated for the first time from the methanol extract of daun dewa. The structures were determined base on spectral evidence including IR, NMR 1D and NMR 2D.
KARAKTERISASI SENYAWA FENOL DARI KAYU BATANG MORUS NIGRA Ferlinahayati Ferlinahayati; Euis Holisotan Hakim; Yana Maolana Syah; Lia Dewi Juliawaty
Molekul Vol 8, No 1 (2013)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (240.526 KB) | DOI: 10.20884/1.jm.2013.8.1.124

Abstract

Tumbuhan Morus merupakan salah satu genus utama dalam famili Moraceae. Senyawa-senyawa turunan fenol merupakan kandungan utama dari genus ini, diantaranya kelompok stilben, 2-arilbenzofuran, flavonoid dan adductDiels Alder. Penelitian ini merupakan bagian dari penelitian mengenai kajian fitokimia terhadap tumbuhan Morus. Ekstraksi dilakukan secara maserasi terhadap kayu batang Morus nigra menggunakan pelarut metanol yang dilanjutkan dengan pemisahan menggunakan berbagai teknik kromatografi sehingga diperoleh senyawa murni. Berdasarkan data-data spektroskopi yang meliputi spektrum UV, IR dan NMR maka senyawa murni hasil isolasi tersebut merupakan senyawa fenol yaitu b-resorsilaldehid.
FLAVANONES FROM THE WOOD OF Morus nigra WITH CYTOTOXIC ACTIVITY Ferlinahayati Ferlinahayati; Yana Maolana Syah; Lia Dewi Juliawaty; Euis Holisotan Hakim
Indonesian Journal of Chemistry Vol 13, No 3 (2013)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (192.38 KB) | DOI: 10.22146/ijc.21277

Abstract

Two flavanone derivatives, norartocarpanone (1) and euchrenone a7 (2) had been isolated for the first time from the methanol extract of the wood of Morus nigra. The structures of these compounds were determined base on spectral evidence, including UV, IR, and NMR. The first compound also confirmed by comparison with the reported data. Cytotoxic properties of these compounds were evaluated against murine leukemia P-388 cells. Euchrenone a7 (2) was found more cytotoxic than norartocarpanone (1) with their IC50 7.8 and 12.7 mg/mL respectively.
α-Glucosidase Inhibitory and A Leptospermone Derivative from Rhodomyrtus tomentosa Ferlinahayati Ferlinahayati; Daniel Alfarado; Eliza Eliza; Budi Untari
Indonesian Journal of Chemistry Vol 20, No 2 (2020)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (19.288 KB) | DOI: 10.22146/ijc.40990

Abstract

One of the treatments for diabetes mellitus disease is to control blood sugar level using an inhibitor of α-glucosidase enzyme. The methanol extracts of the fruit, stem, and leaves of Rhodomyrtus tomentosa were found significant in inhibiting α-glucosidase with an IC50 value of 20.57, 20.36 and 43.99 μg/mL respectively. The ethyl acetate and n-butanol fractions from the methanol extract of R. tomentosa fruit exhibited the potent inhibition (IC50 13.49 and 19.29 μg/mL) compare to acarbose and n-hexane fraction (IC50 383.68 and 1175.16 μg/mL). A leptospermone derivative, rhodomyrtosone D, was isolated from the ethyl acetate fraction of R. tomentosa fruit. The structure of rhodomyrtosone D was identified based on spectroscopic analysis, as well as comparing with literature data. The α-glucosidase inhibition of rhodomyrtosone D (IC50 110.45 μg/mL) was 3.5 fold more potent than acarbose. Thus, R. tomentosa plant could be potential as a natural resource of α-glucosidase inhibitor.
Pembuatan dan Penyuluhan Virgin Coconut Oil di Desa Tanjung Seteko Indralaya dan Manfaatnya Untuk Kesehatan Nurlisa Hidayati; Hermansyah Hermansyah; Ferlinahayati Ferlinahayati; Addy Rachmat; Ahmad Fatoni
Jurnal Kreativitas Pengabdian Kepada Masyarakat (PKM) Vol 5, No 7 (2022): Volume 5 No 7 Juli 2022
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jkpm.v5i7.6192

Abstract

 ABSTRAK Telah dilaksanakan kegiatan pengabdian kepada masyarakat Desa Tanjung Seteko Indralaya. Tujuan kegiatan ini adalah untuk memberikan informasi kepada masyarakat tentang: pengolahan buah kelapa menjadi virgin coconut oil (VCO) dan demonstrasi pembuatan dan pemanfaatan VCO. Kegiatan Pengabdian kepada Masyarakat ini diikuti 20 orang ibu rumah tangga dan remaja putri yang berasal dari desa Tanjung Seteko. Kegiatan yang dilaksanakan adalah memperkenalkan teknologi pembuatan VCO. Selain itu dilakukan juga diskusi dan demonstrasi penggunaan VCO sebagai ramuan yang berguna bagi kesehatan. Penyuluhan yang dilakukan mendapat tanggapan yang positif dari masyarakat. Kegiatan diskusi dan tanya jawab juga mendapat perhatian yang tinggi dari masyarakat. Masyarakat merasa senang karena mendapatkan pengetahuan dan keterampilan tentang teknologi pembuatan VCO. Dengan diberikannya penyuluhan masyarakat juga menjadi faham cara membuat ramuan berbahan dasar VCO. Masyarakat juga berharap kegiatan pengabdian dapat berlangsung secara berkelanjutan, sehingga wawasan mereka akan terus bertambah baik. Kata Kunci: Pembuatan, Penyuluhan, VCO ABSTRACT Community service activities in Tanjung Seteko village Indralaya have been carried out. The purpose of this activity is to provide information to the public about: processing coconuts into virgin coconut oil (VCO) and demonstrations of making and using VCO. This community service activity was attended by 20 housewives and young women from Tanjung Seteko village. The activity carried out to introduce the technology of making Virgin Coconut Oil. In addition, discussions and demonstrations on the use of VCO as an ingredient that is useful for health were also held. The counseling carried out received a positive response from the community. Discussion and question and answer activities also received high attention from the community. People are happy because they get knowledge and skills about VCO manufacturing technology. By providing public education, they also understand how to make VCO-based ingredients. The community also hopes that service activities can take place in a sustainable manner, so that their knowledge will continue to improve. Keywords: Making, Counseling, VCO
Standardization in ethanolic extract of Paronema canescens leaves Dirli Fahmi Rizal; Muharni Muharni; Heni Yohandini; Ferlinahayati Ferlinahayati
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Vol 7, No 3 (2022): October 2022
Publisher : IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24845/ijfac.v7.i3.136

Abstract

The development of traditional medicinal plants as raw materials for herbal drugs needs to be standardized. The aim of the research was to standardise ethanol extract of Paronema. canescens leaves.  The extract was determined specific and non-specific parameters. The organoleptic of  extract has a thick consistency, the colour dark brown has a characteristic non-aromatic odour, and has a slightly bitter taste. The soluble content in water and ethanol of 48.1% and 80. 3%, respectively. The extract contains triterpenoid compounds, steroids, flavonoids and phenols with water content was 8.33%, total ash content of 5.36%,  acid insoluble ash content of 2.16%,  drying shrinkage of 8.0%,  specific gravity of 1.255 g/ml, metal contamination Pb < 0.0628 mg/g, Cd 0.0077 mg/Kg and Cu 0.00282 mg/g, total bacterial  of 0.9 x 101 colonies/g and mould contamination with a value of 0.15 x 101 colonies/g, respectively. Based on the data, all the parameters were measured to meet the standardKeywords: Paronema canescens, standardised, specific parameter, non specific parameter
DIVERSIFIKASI SEDIAAN DAUN SUNGKAI (Paromena canescens Jack.) SEBAGAI MINUMAN KESEHATAN UNTUK MENINGKATKAN IMUN TUBUH Jurnal Pepadu; Muharni Muharni; Efita Efita; Ferlinahayati Ferlinahayati; Julinar Julinar; Bambang Yudono
Jurnal Pepadu Vol. 4 No. 1 (2023): Jurnal Pepadu
Publisher : LPPM UNIVERSITAS MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/pepadu.v4i1.2247

Abstract

Tumbuhan sungkai (Paronema canescens Jack.) merupakan salah satu tumbuhan obat tradisional yang diyakini dapat meningkatkan sistim imun. Hal ini berkaitan dengan kandungan senyawa aktioksidan yang terdapat pada daun sungkai. Konsumsi tumbuhan obat ini dapat disiapkan dalam berbagai bentuk sediaan. Kegiatan ini bertujuan mengedukasi masyarakat tentang penggunaan tumbuhan P. canescens, dan memperkenalkan berbagai bentuk sediaan P. canescens sehingga dapat meningkatkan taraf kesehatan masyarakat. Kegiatan ini dilakukan dengan metode ceramah dan diskusi dengan masyarakat desa Tanjung Pering Indralaya Utara Ogan Ilir, tentang informasi ilmiah yang mendukung penggunaannya secara tradisional dan penyiapan bentuk-bentuk sediaan tumbuhan sungkai (P.canescens). Pada akhir kegiatan dilakukan pengisian kuisioner untuk melihat keberhasilan kegaitan. Hasil kegiatan menunjukkan 75% peserta lebih menyukai bentuk-bentuk sediaan simplisia dibandingan bentuk segar (25%). Peseta juga setuju (skor 90%) cara membuatnya sederhana sehingga tertarik untuk membuatnya, namun 50% peserta berpendapat penyiapannya sama praktisnya dengan penggunaan bentuk segar. Kegiatan ini telah membuka wawasan dan menambah pengetahuan masyarakat dalam menjaga kesehatannya. Masyarakat juga menyatakan kegiatan ini sangat bermanfaat dan perlu adanya kegiatan serupa atau bidang lainnya dimasa yang akan datang.
EDUKASI PENGGUNAAN TUMBUHAN SUNGKAI (Paronema canescens) UNTUK MENURUNKAN KOLESTEROL Jurnal Pepadu; Muharni Muharni; Heni Yohandini; Ferlinahayati Ferlinahayati; Julinar Julinar
Jurnal Pepadu Vol 3 No 1 (2022): Jurnal PEPADU
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/pepadu.v3i1.2296

Abstract

Penyakit kolesterol tinggi merupakan penyakit yang lazim ditemukan pada masyarakat terutama pada usia diatas 40 tahun. Salah satu pemicu tingginya kolesterol adalah hipertensi. Rendahnya taraf hidup masyarakat menyebabkan masyarakat cendrung menggunakan obat tradisional dalam pengobatan penyakitnya. Sungkai (Paronema canescens) merupakan salah satu tumbuhan obat tradisional untuk pengobatan hipertensi dan kolesterol. Kegiatan ini bertujuan mengedukasi masyarakat tentang penggunaan tumbuhan P. canescens, sehingga diharapkan dapat membantu masyarakat mengatasi masalah kesehatannya. Kegiatan ini dilakukan dengan metode ceramah dan diskusi dengan masyarakat desa Tanjung Pering Indralaya Utara Ogan Ilir tentang khasiat dan kegunaan tumbuhan sungkai (P. canescens), informasi ilmiah yang mendukung penggunaannya secara tradisional dan dilakukan dengan cek kolesterol warga. Hasil cek kolesterol menunjukkan dari 25 orang warga yang diperiksa, 4 diantaranya memiliki kolesterol tinggi. Kegiatan ini telah membuka wawasan dan menambah pengetahuan masyarakat dalam mengatasi masalah kesehatannya khususnya masalah hiperkolesterol dengan memanfaatkan tumbuhan obat yang ada disekitarnya. Warga dengan kolesterol tinggi dapat mencoba terapi menurunkan kolesterol menggunakan daun P. canescens.
Shoot Emergence, Leaf Expansion, and Corm Growth in Amorphophallus muelleri Blume Treated with Hydropriming and Shading Dora Fatma Nurshanti; Benyamin Lakitan; Merry Hasmeda; Ferlinahayati Ferlinahayati
AGRIVITA, Journal of Agricultural Science Vol 45, No 1 (2023)
Publisher : Faculty of Agriculture University of Brawijaya in collaboration with PERAGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.17503/agrivita.v45i1.3837

Abstract

A bulbil, as planting material, is difficult to stimulate to grow in a dormant state. This study examines the hydropriming effect on shoot emergence and the shading treatments on leaf and cormel growth during the vegetative stage. The priming was carried out by soaking the bulbils in distilled water for 0, 3, 6, 12, and 24 hours and the shading treatments at 0, 40, and 80 percent. The results show that the imbibition occurred immediately during the first 3 hours and continued to increase up to 24 hours. The bulbil re-drying process reached the pre-treatment water content in less than three days. Significantly the earlier emergence was observed in the plants exposed to the 80% shading. The petiole sheath breakup was not affected by the hydropriming and shading. The konjac planted in the shading treatment produced more sprouts, longer but slender petioles, larger but thinner leaves, and larger cormel size. The differences in fresh and dry weight were more related to tuber moisture content than the direct effect of the shading treatment. The SPAD value of konjac leaves immediately increased within a few days after the application of the NPK fertilizer and consistently lasted for four weeks.
Antibacterial Activity Test of Tropical Plants (Morinda citrifolia) and (Melaleuca leucadendra) against Pneumonia-causing Bacteria Nadila Pitriani; Hermansyah Hermansyah; Ferlinahayati Ferlinahayati
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Vol 8, No 1 (2023): February 2023
Publisher : IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24845/ijfac.v8.i1.8

Abstract

This study aims to determine the antibacterial activity of tropical plants against bacteria that cause pneumonia. The initial stage is to prepare samples of tropical plants that are macerated with methanol and produce a thick extract, namely 38.3881 grams of noni fruit with a yield of 13.422%, and cajuput leaves as much as 11.211 grams with a yield of 3.38%. The next step, each sample was fractionated using VLC then produced ethyl acetate fraction and methanol fraction. Bacterial activity test was carried out by disc diffusion method, and the MIC value was determined by liquid dilution method using UV-Vis spectrophotometry. Based on the results of antibacterial testing, the noni fruit extract and cajuput  extract obtained the most active fraction in response to inhibiting bacteria causing pneumonia (S. pneumonia, S. aureus and K. pneumoniae) was the ethyl acetate fraction with a strong average response zone of inhibition up to very strong with MIC value of ethyl acetate fraction from noni fruit extract 6250 ppm each and MIC value of ethyl acetate fraction from cajuput extract (Melaleuca leucadendra) 390.625 ppm each; 390.625 ppm; and 195.3125 ppm.
Co-Authors Addy Rachmat Ady Mara, Ady Afreni Hamidah Ahmad Fatoni Aldes Lesbani Alfarado, Daniel Bambang Yudono Benyamin Lakitan Budi Untari Cenora, Cindy Cindy Cenora Daniel Alfarado Dasril Basir Desnelli Desnelli Dirli Fahmi Rizal Efita Efita Elfita Elfita Elfita Elfita Elisa Nurnawati Eliza Eliza Eliza Eliza Eliza Eliza Eliza Eliza Eliza Eliza Emir Fikri Endri Junaidi Endri Junaidi, Endri Euis Holisotan Hakim Euis Holisotan Hakim Euis Holisotan Hakim Fatma Fitrya . Fitrya Fitrya Fitrya Fitrya Hanifa Marisa Hanifa Marisa Hary Widjajanti Heni Yohandini Herlina Herlina Hermansyah Hermansyah Hermansyah Hermansyah Hermansyah Hermansyah Hermansyah Hermansyah Julinar Julinar Julinar Julinar Julinar Jurnal Pepadu Juswardi Juswardi Juswardi Juswardi, Juswardi Lenny Anwar Lia Dewi Juliawaty Maryadi Maryadi Merry Hasmeda Mery Hasmeda Mia Tirta Sari Mikha Meilinda Christina MUHAMMAD SAID Muhammad Said Muharni Muharni Muharni Muharni Muharni Muharni Muharni Muharni Muharni Muharni Mustafa Kamal Mustafa Kamal Nadila Pitriani Nelly Erlina Nurlisa Hidayati Nurlisa Hidayati Nurshanti, Dora Fatma Nurshanti, Dora Fatma Poedji Loekitowati Hariani Rian Oktiansyah Ricce Fatsiami Rizdha Apriyaty Rizkiani, Delisa Roby Pahala J Gultom Rofiqoh, Purnama Ria Salni Salni Salni Sarifatun Nisa Setiawati Yusuf Shaum Shiyan Suheyanto Suheryanto Susilawati, Susilawati Tarmizi Taher Yana Maolana Syah Zaidan, Zaidan