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All Journal JPMS (Jurnal Pendidikan Matematika dan Sains) Jurnal Pengajaran MIPA Jurnal Pengajaran Matematika dan Ilmu Pengetahuan Alam Jurnal Sains dan Teknologi Kimia Jurnal Riset dan Praktik Pendidikan Kimia TARBIYA : Journal Education in Muslim Society Indonesian Journal of Science and Technology Jurnal Tadris Kimiya Jurnal Penelitian Pendidikan IPA (JPPIPA) Al-Kimia Journal of Science Learning Indonesian Journal of Chemistry Biosaintifika: Journal of Biology & Biology Education Jurnal Kartika Kimia Jambura Journal of Educational Chemistry International Journal of STEM Education for Sustainability Journal of Educational Sciences ICONESTH JIPI (Jurnal IPA dan Pembelajaran IPA) Jurnal Pengabdian Isola Jurnal Riset dan Praktik Pendidikan Kimia Jurnal Bioteknologi & Biosains Indonesia (JBBI) Jurnal Bioteknologi & Biosains Indonesia
Heli Siti Halimatul
Universitas Pendidikan Indonesia
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Energy Engineering Environmental Science Health Professions Library & Information Science Materials Science & Nanotechnology Mathematics Neuroscience Nursing Physics Public Health Social Sciences Other

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EVALUATION OF ANTIBACTERIAL ACTIVITY OF PHYCOCYANIN PEPTIDES FROM SPIRULINA PLATENSIS THROUGH MULTIPLE MOLECULAR DOCKING STUDY Arindita, Ni Putu Yunika; Munawaroh, Heli Siti Halimatul; Aisyah, Siti; Khoiriah, Selmi Fiqhi
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 10 No. 2 (2023)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2023.2379

Abstract

Peptides derived from the phycocyanin pigment of Spirulina plantesis were screened to identify potential natural antibacterial candidates. In silico protein hydrolysis was performed to obtain active peptides, and a multiple molecular docking (MLD) approach was used to to predict the synergistic mechanisms of various peptide combinations with their respective receptors. Nine phycocyanin peptides showed interaction values ranging from -5.1 to -6.0 kcal/mol, compared to the native ligand (BB-78485) with a value of -9.7 kcal/mol. The results demonstrated a synergistic effect, as the binding affinity of peptide combinations exceeded that of individual peptides and the native ligand. Hydrophobic bonds and van der Waals forces played a crucial role in binding to the active site of 2VES proteins. However, ADME studies revealed that two peptides, YCL and ASYF, had poor pharmacokinetic properties. Overall, this study highlights the potential of phycocyanin peptides as antibacterial agents through the application of MLD.
Pengembangan Instrumen Tes Kimia Framework PISA untuk Mengukur Kemampuan Literasi Sains Siswa Madrasah Aliyah Winda Ariani; Nahadi; Heli Siti Halimatul Munawaroh
Jurnal Penelitian Pendidikan IPA Vol 11 No 11 (2025): November
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i11.12808

Abstract

This study aims to produce a valid and reliable PISA-based chemistry test instrument on the acid–base concept to measure Madrasah Aliyah students’ scientific literacy. The test instrument was developed using the ADDIE model (analyze, design, develop, implement, and evaluate). A total of 25 multiple-choice questions were tested on 60 Grade XII students majoring in natural sciences at Madrasah Aliyah in Subang. From the Rasch analysis, a Cronbach's alpha value of 0.71 indicates that the reliability of the test instrument is acceptable. In addition, the person reliability value of 0.67 indicates that the respondents' answers were quite consistent, and the item reliability value of 0.83 indicates that the reliability of the questions was good. All questions were declared valid because they met the outfit MNSQ, outfit ZSTD, and Pt-Measure Correlation criteria. The level of difficulty of the items was distributed into five very easy items, seven easy items, nine difficult items, and four very difficult items. The discriminating power of the items was classified into 24 items in the good category and one item in the sufficient category. In addition, 21 items had well-functioning distractors, while four items had distractors that did not function well.
Mapping Performance Assessment Tools of Practical Skills in Chemistry Education: Evidence from a Systematic Review Faradhilla Bonita; Nahadi; Heli Siti Halimatul Munawaroh
Jurnal Penelitian Pendidikan IPA Vol 12 No 5 (2026)
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v12i5.14258

Abstract

Performance assessment has emerged as an important approach in chemistry education to address the limitations of conventional testing. This study aims to systematically review the implementation of performance-based assessments in chemistry, focusing on instrument typology, educational context, and targeted competencies. Guided by the PRISMA protocol, a comprehensive search was conducted in the Scopus database for peer-reviewed research articles published between 2015 and 2025. Due to the very strict inclusion criteria that focused exclusively on validated chemistry-specific instruments, nine selected articles were synthesized. Results indicate that analytical rubrics remain the most dominant format (67% of reviewed tools), with digital video-based assessments emerging as a recent trend, while 88% of implementations are skewed towards higher education. These authentic tools consistently report positive impacts on students' practical competence and procedural engagement. However, pedagogical challenges remain: current instruments often fail to capture deep conceptual reasoning due to the high cognitive load experienced by students during active tasks. This review concludes that while performance assessments effectively measure technical compliance, global standardization of the Evidence-Centered Design (ECD) framework is urgently needed to address the current fragmentation of instruments and systematically align laboratory evidence with measurable conceptual milestones.
Enhancing Students' Conceptual Understanding of Hess's Law Through a Discovery Learning Model Integrated with a Simulator and Worksheets Nopiyanti Nopiyanti; Gun Gun Gumilar; Heli Siti Halimatul Munawaroh; Ijang Rohman; Muhammad Nurul Hana; Miarti Khikmatun Nais
Jambura Journal of Educational Chemistry Vol 8, No 2 (2026): August
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/jjec.v8i2.40151

Abstract

This study addresses the limited integration of Discovery Learning, a Hess’s Law Enthalpy Change Determination Simulator, and student worksheets (LKM). These components have generally been implemented separately or in different combinations in previous studies, and simulation-based learning in Hess’s Law remains limited. The study aimed to examine students’ conceptual understanding of Hess’s Law, both overall and across specific learning objectives, after implementing the Discovery Learning model integrated with a Hess’s Law Enthalpy Change Determination Simulator and student worksheets. The research employed a pre-experimental one-group pretest–posttest design involving 29 senior high school students. Data from the conceptual understanding test were analyzed using descriptive and inferential statistics. The paired-sample t-test revealed a statistically significant improvement from 35.06 to 63.22 (t= −8.11, p < 0.001). At the level of specific learning objectives, the Wilcoxon signed-rank test showed that students achieved greater gains in inferring Hess’s Law from comparisons of reaction pathways than in determining enthalpy change based on Hess’s Law. These findings indicate that the instructional approach was associated with improved conceptual understanding of Hess’s Law. This study suggests that integrating Discovery Learning with a Hess’s Law Enthalpy Change Determination Simulator and structured worksheets may support students’ conceptual understanding of Hess’s Law and serve as a practical instructional strategy in chemistry education.
Critical Thinking through Three Levels of Representation: An Analysis of Carbohydrate Concepts in Chemistry Textbooks Nurhalimah Hasibuan; Sjaeful Anwar; Heli Siti Halimatul Munawaroh
International Journal of STEM Education for Sustainability Vol 6, No 1 (2026)
Publisher : Gemilang Maju Publikasi Ilmiah (GMPI) 

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53889/ijses.v6i1.809

Abstract

For a student to gain a deeper understanding of concepts in chemistry, they need to learn concepts at three levels of representation: macroscopic, submicroscopic, and symbolic. The three levels of representation of information are crucial for developing critical thinking skills. But the textbook, which is the main learning resource, plays a vital role in helping a student relate concepts at the three levels. The objective of this research was to assess the display of carbohydrate representation at three levels in ten general chemistry textbooks. In order to examine 120 visual representations, this research employed qualitative content analysis, with five criteria developed from the work of Gkitzia et al. (2020). Criteria C1-C5 include the following: type of representation (C1), interpretation of surface characteristics (C2), relationship to text (C4), presence and nature of captions (C5), and level of correlation between elements that comprise the different representations. Thirdly, the usefulness of the proposed criteria was compared to chemistry textbooks. The results showed that there was a dominance of representations at the symbolic level. Moreover, some of the representations were found to have insufficient subtitles to give meaning, especially at the submicroscopic level. The conceptual understanding of students can be impaired by the dominance of symbolic representations and the absence of visual support for other levels. To ensure that critical thinking is done effectively, this study stresses the need to develop learning materials that incorporate the three levels of representation in a balanced manner. These five criteria can also be used to analyze existing school textbooks and to design new Chemistry textbooks.
Co-Authors Abdullah, Norazilawati Adi Aliyan Ahmad Aminudin Ahmad Mudzakir Andhika Baruri Andini Saputri Anwar*, Sjaeful Arindita, Ni Putu Yunika Asep Bayu Dani Nandiyanto Asep Kadarohman Asep Kadarohman Asep Supriatna Asri Peni Wulandari Atep Rian Nurhadi Bella Azzahra Hadiyat Buchori Muslim Cecep Jaenudin Devita Marlina Venessa Dhesy Puspitasari Diana Rochintaniawati Faradhilla Bonita Fitriani Tekistia Darmawan Gebi Dwiyanti Gun Gun Gumilar Gun Gun Gumilar Gun Gun Gumilar GunGun Gumilar Hayun Rizki Yulistia HERNANI - Ijang Rohman Ijang Rohman Indra Tri Gunawan Iqbal Musthapa Irawan, Nisrina Zahira Putri Karina Mulya Rizky Khoiriah, Selmi Fiqhi Miarti Khikmatun Nais Mr Sjaeful Anwar Muftiasih, Agnia Muhamad Nurul Hana Muhammad Nurul Hana Muhammad Nurul Hana Muhammad Nurul Hana Munawaroh - Nahadi Nais, Miarti Khikmatun Nopiyanti Nopiyanti Norazilawati Abdullah Nuraeni, Neng Sri Nurhalimah Hasibuan oktariani Omay Sumarna R. Riandi, R. Rahmat Setiadi Rahmat Setiadi Ratu Syifa Khaerun Nisa Herawan Ratulani Juwita RATULANI JUWITA, RATULANI Ridha Indah Lestari Saputri, Andini Siti Aisyah Siti Latifah Nata Sjaeful Anwar Sjaeful Anwar Soja Siti Fatimah Sunarya, Yaya Tedi Kurniawan Wawan Wahyu Winda Ariani Windra Yuniarsih Yaya Sonjaya Yuniarsih, Windra Zackiyah, Zackiyah