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Journal : Calvaria Medical Journal

STUDI LITERATUR SISTEMATIS TENTANG PENGARUH KONSUMSI ALKOHOL TERHADAP PENYAKIT LIVER KRONIK hernando, wiowen izaaz; Hernanda, Pratika Yuhyi
Calvaria Medical Journal Vol 2 No 1 (2024): Edisi Juni 2024 (available online Juli 2024)
Publisher : Institute for Research and Community Services (LPPM) of University of Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/cmj.v2i1.40

Abstract

Introduction: Health issues occur worldwide, including chronic liver diseases, which are often caused by alcohol consumption. Excessive alcohol intake can lead to liver diseases, alcoholic hepatitis, hepatocellular carcinoma (HCC), fibrosis, and cirrhosis. This literature review aims to analyze the extent of the relationship between alcohol consumption and the occurrence of chronic liver diseases. The study uses a literature review method, collecting information related to alcohol consumption and chronic liver disease events. The data are then analyzed descriptively, drawing from national and international journals from the past ten years, as well as textbooks. Results: Alcohol consumption can increase the risk of liver cirrhosis by up to 10.23 times, 3.43 times for liver cancer (HCC), and 3.88 times for hepatitis. The highest mortality risk (HR) for fatty liver occurs in both men and women with alcohol consumption ≥70g/day. Conclusion: This literature study indicates a significant association between alcohol consumption and an increased risk of liver cirrhosis and liver cancer.
HUBUNGAN BERBAGAI MACAM FAKTOR RISIKO KANKER KOLOREKTAL DENGAN MASA SURVIVAL PASIEN KANKER KOLOREKTAL DI RSUD NGANJUK Listya Santoso, Ardanna; Hernanda, Pratika Yuhyi; Sugeng, Maria Widijanti; Sanjaya, Ayling
Calvaria Medical Journal Vol 3 No 2 (2025): Edisi Desember 2025
Publisher : Institute for Research and Community Services (LPPM) of University of Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/s3vcq410

Abstract

Background: Colorectal cancer is one of the types of cancer with a high mortality rate worldwide, including in Indonesia. Objective: To analyze the relationship between various risk factors (history of smoking, obesity, alcohol consumption, family history of cancer, and comorbid diseases) and the survival of colorectal cancer patients at Nganjuk General Hospital. Methods: This study used an observational analytic design with a cross-sectional approach. Data were taken from the medical records of 42 colorectal cancer patients treated at Nganjuk General Hospital. Results: The findings showed that none of the patients had a history of smoking, obesity, alcohol consumption, or family history of cancer. However, there is a significant relationship between comorbid diseases and the survival of colorectal cancer patients (p-value = 0.048). Conclusion: The importance of managing comorbid diseases to improve the survival of colorectal cancer patients.