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All Journal Jurnal Kesehatan Andalas Majalah Kedokteran Andalas Bioscientia Medicina : Journal of Biomedicine and Translational Research Human Care Journal Indonesian Journal of Global Health research Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Riset Ilmiah Ophthalmologica Indonesiana Jurnal Sains, Teknologi dan Kesehatan
Vitresia, Havriza
Fakultas Kedokteran Universitas Andalas
Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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HUBUNGAN PENGGUNAAN ALAT KONTRASEPSI HORMONAL DENGAN STABILITAS TEAR FILM : SEBUAH TINJAUAN NARATIF Praja, Fathira Luthfi Nuresa; Hendriati, Hendriati; Elmatris, Elmatris; Vitresia, Havriza; Irawati, Lili; Mahata, Liganda Endo
SINERGI : Jurnal Riset Ilmiah Vol. 2 No. 6 (2025): SINERGI : Jurnal Riset Ilmiah, Juni 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v2i6.1329

Abstract

Background : Tear film is a fluid-filled layer that protects the eyes from the external environment. This layer consists of three layers, namely lipid, aqueous and mucin. Tear film stability is seen as one of the main characteristics of eye health. failure to maintain balance Tear film can cause dry eyes. One of the causes of dry eyes is an imbalance of steroid sex hormones such as estrogen, progesterone and androgens. These hormones have mRNA receptors on the surface tissues of the eye that are susceptible to hormonal contraceptives. Objective : This literature study aims to explore various original research literature on the relationship between the use of hormonal contraceptives and the stability of Tear film.  Methods : Narrative reviews of literature searched through the Pubmed and Google Scholar databases, then selected based on established inclusion and exclusion criteria. Results : There are 6 literatures with 444 women of childbearing age with an age range of 20-45 years who use the TBUT and Schirmer examinations. Conclusion : There is no relationship between the use of hormonal contraceptives and the stability of tear film
Multilayered-Amniotic Membrane Transplantation in Gunshot Powder Injury: A Case Report Amanda, Nitia; Havriza Vitresia
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 3 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i3.948

Abstract

Background: Amniotic membrane transplantation has been widely used to repair various ocular surface conditions, including inflammatory, infectious, traumatic, and neoplastic conditions, with satisfactory results. a case of a 34-year-old male hit by a gunpowder explosion. Case presentation: We reported a case of a 34-year-old male hit by a gunpowder explosion. The right eye was hyperemic and felt blurry after the incident. On examination of the right eye, visual acuity was 20/150, and foreign bodies and erosion were found in the cornea. The patient planned to do foreign body extraction followed by a multilayered-amniotic membrane transplantation (ML-AMT) procedure. On the first and second day of follow-up, on the right eye, the visual acuity was 1/300, palpebral edema was decreased, and subconjunctival hemorrhage was found. On the cornea, there were ML-AMT and bandage contact lenses. Conclusion: Gunshot powder injury in the eyes is quite rare. The damage that can occur ranges from corneal epithelium abrasion to perforation and rupture of the eyeball. AMT has been successfully used in the management of eye trauma with defects on the ocular surface.
Changes in Retinal Ganglion Cell (RGC) and Retinal Nerve Fiber Layer (RNFL) Thickness in Children with Type 1 Diabetes Mellitus at Dr. M. Djamil General Hospital, Padang, Indonesia lonanda, Gama Agusto; Kemala Sayuti; Havriza Vitresia; Hendriati; Andrini Ariesti; Weni Helvinda
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 8 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i8.1047

Abstract

Background: Type 1 diabetes mellitus (DM) is a chronic metabolic disorder that causes hyperglycemia and increases the risk of morbidity and mortality. Diabetic retinopathy, a microvascular complication that often occurs in DM patients, can cause visual impairment and even blindness. Regular eye examinations are important for early detection of diabetic retinopathy. Optical coherence tomography (OCT) is a non-invasive method that can be used to measure the thickness of retinal layers, including RGC and RNFL. It is thought that thinning of the retinal layer can be a sensitive biomarker in detecting diabetic retinopathy in type 1 DM patients. This study aims to determine changes in RGC and RNFL thickness in children with type 1 DM. Methods: This cross-sectional design analytical observational study was conducted at the eye polyclinic of Dr. M. Djamil General Hospital Padang in November 2023-March 2024. A total of 46 eyes from 46 people, divided into two groups: the type 1 DM group and the control group, were recruited in this study. RGC thickness was measured using AS-OCT GC-IPL thickness analysis and RNFL with optic disc RNFL thickness analysis. Data analysis was carried out using the unpaired T-test. Results: The results showed RGC depletion in the type 1 DM group (RGC 83.48 ± 3.75) compared to the control group (RGC 86.70 ± 4.87) with a value of p = 0.016 (p < 0.05). There was no statistical difference in RNFL thickness between the type 1 DM group (RNFL 102 ± 11.80) and the control group (RNFL 100.96 ± 10.97) with a value of p = 0.581 (p> 0.05). Conclusion: This study found RGC thinning in type 1 DM patients, but did not find differences in RNFL thickness between the two groups. This RGC depletion is thought to be caused by apoptosis of retinal neuronal cells due to chronic hyperglycemia. Examination of RGC thickness with OCT can be developed as an early detection of diabetic retinopathy in children with type 1 DM.
Ocular Manifestations and Risk Factors of HIV in a Single-Center Observational Study at Dr. M. Djamil General Hospital, Padang, Indonesia Rosa, Havilah Zeki; Havriza Vitresia
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 11 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i11.1111

Abstract

Background: Human immunodeficiency virus (HIV) infection is associated with various ocular manifestations, impacting visual health and quality of life. This study aimed to investigate the spectrum of ocular manifestations and their associated risk factors in HIV-positive individuals at Dr. M. Djamil General Hospital, Padang, Indonesia. Methods: This single-center observational study included HIV-positive patients presenting with ocular complaints at Dr. M. Djamil General Hospital between 2019 and 2021. Comprehensive ophthalmic examinations were conducted, and data on demographics, HIV disease stage, CD4+ T-cell count, antiretroviral therapy (ART) status, and ocular findings were collected. Statistical analysis was performed to identify associations between risk factors and specific ocular manifestations. Results: A total of 149 HIV-positive patients were included in the study, with 7 (4.7%) presenting with ocular manifestations. The most common ocular manifestation was cytomegalovirus (CMV) retinitis (57.1%), followed by retinal nerve fiber layer (RNFL) thinning (42.9%). Other manifestations included visual field disturbances and herpes zoster ophthalmicus (HZO). Low CD4+ T-cell count (<200 cells/μL) was significantly associated with CMV retinitis (p < 0.05). Conclusion: CMV retinitis and RNFL thinning were the predominant ocular manifestations in this HIV-positive cohort. Low CD4+ T-cell count emerged as a significant risk factor for CMV retinitis. Early detection and prompt management of ocular manifestations are crucial to prevent visual impairment in HIV-positive individuals.
Clinical Spectrum of Orbital Cellulitis: Case Series From Subperiosteal Abscess to Life-Threatening Cavernous Sinus Thrombosis Putri Amanda; Havriza Vitresia
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 4 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i4.1242

Abstract

Background: Orbital cellulitis encompasses a range of orbital infections with varying severity. This case series highlights the diverse clinical presentations, management strategies, and outcomes of orbital cellulitis, emphasizing the importance of prompt diagnosis and treatment. Case presentation: We present two cases of orbital cellulitis with contrasting presentations. The first case involved a 16-year-old male with acute rhinosinusitis who developed severe orbital cellulitis complicated by cavernous sinus thrombosis (CST), requiring aggressive medical and surgical interventions. The second case involved a 2-month-old female with a subperiosteal abscess secondary to ethmoid and maxillary sinusitis, who responded well to medical management alone. Conclusion: Orbital cellulitis presents a wide spectrum of clinical scenarios, ranging from localized infections to life-threatening intracranial involvement. Early recognition, appropriate imaging, and timely intervention are crucial for optimizing outcomes. While CST necessitates aggressive measures, subperiosteal abscesses can often be managed medically, particularly in young children.
Co-Authors Adrial Adrial, Adrial Afriwardi Afriwardi Agustin Vira Agustin Vira Amanda Priska Diananti Amanda, Nitia Ambriani, Desy Andrini Ariesti Andrini Ariesti Anum, Qaira Arfiani Rusjdi, Dina Ariani, Novita Astria Rima Rara Yuswir Astria Rima Rara Yuswir Desy Ambriani Dolly Irfandy Dzulkifli, Dzulkifli Eldi Sauma Elmatris Sy Endrinaldi Ennesta Asri Ennesta Asri Fadrian, Fadrian Ferry Indratno Fika Tri Anggraini Gardenia Akhyar Getry Sukmawati Getry Sukmawati Getry Sukmawati Getry Sukmawati Getry Sukmawaty Helery, Muhammad Arsyan Hendriati Hendriati, Hendriati Humaira, Fatihah Annisa Indah Indria Sari Indah Indria Sari Julita Julita Julita Julita Karniela Ayuni Putri Kemala Sayuti Lili Irawati Linda Wira Putri lonanda, Gama Agusto Mahata, Liganda Endo Muhammad Hidayat Nabila, Salsya Nadhifah Salsabila Noverial, Noverial Novian Novian Novian Novian Praja, Fathira Luthfi Nuresa Putri Amanda Putri Nirmala Dewi Putri, Linda Wira Rahmi Fatma Sari Raihana Rustam Raisa Hussein Rasyid, Hauda El Rendra Darma Satria Rendra Darma Satria RENI ANGRAINI Resti, Dina Rika Desviorita Rika Desviorita Rima Semiarty Rina Gustia Rina Gustia Rince Liyanti Rini Gusya Liza, Rini Gusya Rizki Dwayana Rizki Dwayana Rosa, Havilah Zeki Rustini Rustini Satya Wydya Yenny Sukmawati, Getry Tutty Ariani Tutty Ariani Vera Vera Weni Helvinda