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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Jurnal Kedokteran Diponegoro Jurnal Media Gizi Indonesia (MGI) Majalah Kedokteran Sriwijaya GIZI INDONESIA Tasyri` : Jurnal Tarbiyah-Syari`ah-Islamiyah Jurnal Psikologi Jambi MEDIC MEdical Dedication Journal of Medical Studies MGMI
Ahmad Syauqy
Jurusan Kedokteran FKIK UNJA
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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The potential of dadih in increasing iron intake and its effect on Ret-He and sTfR in adolescent girls Annisa Furkaniaty; Edward Kurnia Setiawan Limijadi; Anang Mohamad Legowo; Ahmad Syauqy; Gemala Anjani
Media Gizi Mikro Indonesia Vol. 15 No. 2 (2023): Media Gizi Mikro Indonesia (MGMI)
Publisher : Poltekkes Kemenkes Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29238/mgmi.v15i2.2038

Abstract

Background : Dadih is a fermented milk product that contains probiotics. Probiotics can increase the bioavailability of iron so that it can help in the effort to prevent iron deficiency anemia, especially in adolescent girls. Laboratory examinations that can be done to diagnose iron deficiency anemia include reticulocyte hemoglobin equivalent (Ret-He) and soluble transferrin receptor (sTfR). Objective : This study aims to determine the effect of dadih feeding on ret-he and sTfR levels. Method : This study used a randomized pre-posttest controlled group design with 40 healthy adolescent girls aged 12-15 years who were divided into 2 groups, control (KK) and intervention (KI). The participants received dadih and a placebo as much as 100 grams with a frequency of once a day. The study was conducted for 14 days. Statistical analysis using the Wilcoxon Test, Paired T-Test, and Mann-Whitney. Result : The results showed an increase in iron and protein intake after being given dadih. Ret-He level after being given dadih decreased but there was no significant difference (p = 0.088), while sTfR level increased and there was no significant difference (p = 0.322). There was no significant difference in Ret-He and sTfR levels before and after the intervention between KK and KI (p>0.05). Conclusion : Giving dadih alone for 14 days with a frequency of once a day can increase iron and protein intake but has not had a significant effect on Ret-He and sTfR levels in healthy adolescent girl.
Histopathological Profile of Hepatic Steatosis in High Fat Diet-Fed Rats Treated with Rhodomyrtus Tomentosa Leaf Ethanolic Extract Rahman, Ravi Aulia; Ekaputri, Tia Wida; Enis, Rina Nofri; Ahmad Syauqy; Raihanah Suzan; Hasna Dewi
Journal of Medical Studies Vol. 6 No. 1 (2026): Journal of Medical Studies
Publisher : Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/joms.v6i1.52138

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Background: A high-fat diet can increase cholesterol levels and trigger fat accumulation in the liver, causing steatosis. Karamunting leaves (Rhodomyrtus tomentosa) contain flavonoids, saponins, and phenolic compounds that have antioxidant potential and can modulate lipid metabolism. However, the effects of its extract on liver histology in animals induced with a high-fat diet have not been widely studied. Objective: This study aimed to determine the effects of various doses of ethanol extract of Rhodomyrtus tomentosa leaves on liver steatosis in rats induced with a high-fat diet. Methods: An experimental study with a posttest-only control group design was conducted using 25 male Wistar rats divided into five groups: a negative control group (Na-CMC 0.5% 500 mg), a positive control group (simvastatin 0.9 mg/kg BW), and three treatment groups administered Karamunting leaf extract at doses of 200, 400, and 800 mg/kg body weight. After induction with a high-fat diet, the rats received treatment. The liver tissue was then processed into histological sections using hematoxylin and eosin (H&E) staining, examined microscopically, and analyzed using ImageJ software. The collected data were analyzed using ANOVA. Results: The highest percentage of steatosis was found in the negative control group (1.56%) and the lowest in the positive control group (0.44%). The treatment groups showed steatosis values of 1.02% (E200), 0.54% (E400), and 0.81% (E800). The ANOVA results (p-value 0.078) showed no significant differences between the groups. Conclusion: There was no significant effect of various doses of Rhodomyrtus tomentosa leaves ethanol extract on hepatic steatosis in rats induced with a high-fat diet.
Co-Authors Agita Dianingsih Aidil Rahmat Ilham Amelia Dwi Fitri, Amelia Dwi Anang M Legowo Anati Purwakanthi Anggelia Puspasari Ani Margawati Annisa Furkaniaty Armaidi Darmawan Attiya Istarini Ave Olivia Rahman Betty Marlina Budi Justitia Citra Maharani Edward Kurnia Setiawan Limijadi Ekaputri, Tia Wida Elfiani Erny Kusdiyah Esa Indah Ayu, Esa Indah Fadhila, Farah Rosyihana Fairuza, Putri Azka Fillah Fithra Dieny Fitriyanti Fitriyanti Fitriyanti Gemala Anjani Hanina Hanna Wydia Gultom Harahap, Huntari Hasna Dewi Helena Ayatasya Kusuma Cantika Herlambang Herlambang Humaryanto, Humaryanto I Dewa Gede Angga Pramana Iskandar, Mirna Marhami Ivo Amrina Rasyada Juanda, Syahreza Hadi Lipinwati ., Lipinwati MARTHA ARDIARIA Miftahul Jannah Amir Miftahul Jannah Jailani Mirna Iskandar NATALIA DAMAYANTI Nuryanto Nuryanto Okta Arizki Rachma Purwanti Rahman, Ravi Aulia Rani Puspita Rina Nofri Enis Samsirun Halim Sotianingsih, Sotianingsih Sri Yusfinah Masfah Hanum Suzan, Raihanah Tengku Arief Buana Perkasa Wahyu Indah Dewi Aurora Zikri, Rahmat