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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Jurnal Biologi Tropis Devotion: Journal of Research and Community Service Unram Journal of Community Service (UJCS) Biofaal Journal Rumphius Pattimura Biological Journal Balobe: Jurnal Pengabdian Masyarakat Kalwedo Sains (KASA) BAKTI : Jurnal Pengabdian Kepada Masyarakat PENGAMATAN: Jurnal Pengabdian Masyarakat untuk Ilmu MIPA dan Terapannya
Martha Kaihena
Jurusan Biologi FMIPA dan Program Pendidikan Dokter Universitas Pattimura Ambon, Jl. Dr. Tamaela, Kampus Universitas Pattimura Ambon
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Social Sciences Other

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Journal : Rumphius Pattimura Biological Journal

 1 
THE EFFECT OF SEVERAL TOOTHPAST ON THE GROWTH OF Streptococcus mutans Nawaly, Hermanus; Pagaya, Joseph; Kaihena, Martha
RUMPHIUS Vol 2 No 1 (2020): RUMPHIUS Pattimura Biological Journal
Publisher : Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/rumphiusv2i1p011-018

Abstract

This study aims to determine the effect of several toothpastes on the growth of Streptococcus mutans which is the main cause of tooth decay. The study used 5 types of toothpaste, namely toothpaste A, toothpaste B, toothpaste C, toothpaste D, and toothpaste E. The antibacterial testing method used the diffusion method with the cup-plate technique. The significance level of each type of toothpaste was measured using a completely randomized design followed by a Tukey test to see differences in toothpaste treatment. The results showed that toothpaste A with active ingredients Monofluorophosphate Sodium 1.12%, Triclosan 0.3%, Calcium Glycerophosphate 0.13% had the largest average resistance zone of 27.3 mm. Whereas Toothpaste E with the active ingredient 0.08% Sodium Monofluorophosphate, 0.01% Sodium Fluoride has the smallest average resistance zone, which is 14.25 mm. The diameter of the ANOVA test zone of several types of barrier toothpaste against Streptococcus mutans at 95% confidence intervals showed that there was a significant difference.
EFFECTIVENESS OF Sargassum sp EXTRACT IN REDUCE BLOOD SUGAR LEVELS AND ACCELERATE WOUND HEALING ON THE SKIN OF DIABETES MELLITUS MICE (Rattus novergicus) Kaihena, Martha; Umagapi, Muhammad Cesar; Kaliky, Arief Rahman Shabri; Tarangi, Filep Marfil; Ukratalo, Abdul Mahid
RUMPHIUS Vol 6 No 2 (2024): RUMPHIUS Pattimura Biological Journal
Publisher : Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/rumphiusv6i2p093-100

Abstract

Diabetes Mellitus is a metabolic disorder characterised by elevated blood sugar levels beyond normal ranges, resulting from reduced secretion of the hormone insulin by pancreatic β cells and/or impaired insulin action. Diabetes therapy is often overseen by regulating blood glucose levels regularly and preventing or reducing the risk of complications. Sargassum sp is a variety of brown seaweed native to Indonesia with possible antioxidant and antidiabetic properties. This study seeks to evaluate the efficacy of Sargassum sp extract in lowering blood sugar levels and speeding up wound healing on the skin of diabetic mice. This is an experimental study that uses mice as experimental subjects. The mice were categorised into 5 groups (K-, K+, P1, P2, and P3). Their initial blood sugar levels were recorded, a skin incision was performed, and STZ was administered. When blood sugar levels rise, the K+ group receives metformin; on the other hand, P1, P2, and P3 are administered Sargassum sp extract at a specified dosage. The data were examined using ANOVA and SPSS. The analysis revealed that the water content of Sargassum sp was 4.32%, and the yield value of the concentrated extract was 8.75%. The ethanol extract of Sargassum sp has been revealed to lower blood sugar levels and speed up the wound healing process in mice with diabetes mellitus. The effects observed include decreased blood sugar levels and enhanced wound healing percentage, which are dose-dependent.
EFFECTIVENESS OF FINGER LEAF INFUSION (Psophocarpus tetragonolobus (L.) DC) ON THE MALARIA MODEL OF RATS (Rattus norvegicus) Kaihena, Martha; Samson, Efraim
RUMPHIUS Vol 1 No 1 (2019): RUMPHIUS Pattimura Biological Journal
Publisher : Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/rumphiusv1i1p025-032

Abstract

Winged bean is a type of plant that is used as traditional medicine. This study aims to determine the effectiveness of winged bean leaf infusion (Psophocarpus tetragonolobus(L.) DC) against white rat (Rattus norvegicus) model of malaria. The method used in this research is completely randomized design with 4 treatment groups and 3 replications consisting of a control group without being given an infusion (P1), a group that was given an infusion of concentrations: 31.25 mg/mL (P2), 62.5 mg/ mL(P3), and 125 mg/mL (P4). This study used 20 male rats, of which 5 rats including as donor mice. Donor mice were infected with Plasmodium berghe and left until the parasitemia percentage reached> 20%. Then 4 groups of model mice were infected with Plasmodium berghei. Observations were made for 7 days, starting from day 0 (before treatment), 4 days during treatment and 2 days after treatment. The percentage of parasitemia was calculated starting from the day before administration of winged bean leaf infusion (IDK) until the 7th day. The results of this study indicate that IDK can inhibit parasite growth by reducing the level of parasitemia along with increasing concentrations, namely (P2) of 73.78%; (P3) of 89.33%; and (P4) of 93.69%. It can be concluded has potential in inhibiting the growth of Plasmodium berghei in the rat model of malaria with an effective concentration of 31.25 mg/mL.
Co-Authors Adriana Hiariej, Adriana Adrien Jems Akiles Unitly Amos Killay Anneke Pesik Batlayeri, Sentia CECILIA ANNA SEUMAHU Efraim Samson, Efraim Handy Erwin Pier Leimena Henaulu, Adudin H Hermanus Nawaly Hitalesiakwane, Yesty E. Jotlely, Hery Kaliky, Arief Rahman Shabri Kaliky, Nunun Ainun Putri Sari Banun Kubela, Dormatina La Eddy Lapu, Petrus Luarwan, Welmince T. Mainassy, Meilissa C Manurung, Brian Saputra Moniharapon, Debby Dijola Moniharapon, Mechiavel Nindatu, Maria Nusaly, Windy Natalia Pagaya, Joseph Patty, Kristi Lenci Pieter Agusthinus Riupassa Pieter Kakisina Ramadhany, Muhammad Reza Ratulewen, Desi Ellida Riupassa, Pieter A. Sahertian, Dece Elizabeth Sairudy, Albertus Salamena, Fuadiska Seumahu, Cecelia Anna Tahapary, Patrcik Indurian Tarangi, Filep Marfil Tetrapoik, Jenromp Ana Putri Moto Tuhumuri, Evelin Ukratalo, Abdul M Ukratalo, Abdul Mahid Umagapi, Muhammad Cesar