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VO2max Berkorelasi Negatif dengan Kemampuan Tahan Nafas (Apnea) Kukuh Pambuka Putra; Ferry Ferdy Karwur; Nurul Wahidatul Hidayati
Journal of Sport Science and Education Vol 5 No 2 (2020)
Publisher : Fakultas Ilmu Olahraga, Universitas Negeri Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26740/jossae.v5n2.p139-147

Abstract

Free diving (freedive) depends on the ability to hold the breath (apnea). Apnea is thought to have a correlation with the body's ability to consume oxygen (VO2max). This research aims to study the correlation between VO2max and apnea ability. Subjects in this study were men aged 20-25 years as many as 36 people. VO2max measured using MFT test, while the measurement of apnea ability is represented by the duration of apnea as measured by the duration of sitting still under water. The results of one-way correlation tests were found to be p<0.05, which means there was a correlation between VO2max and apnea duration. While the correlation coefficient of -0.44 shows that the direction of the correlation is negative with the strength of the correlation is weak. From these results it can be concluded that the higher VO2max there is a tendency for apnea ability to be lower. 
Studi epidemiologi penyakit metabolik di kota Tomohon Mayang Januarti Permatasari; Ferry Fredy Karwur; Retno Triandhini; Rosiana Eva Rayanti; Rully Toar Tumanduk
Berita Kedokteran Masyarakat (BKM) Vol 34, No 11 (2018): Proceedings of the 4th UGM Public Health Symposium
Publisher : Fakultas Kedokteran Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (251.311 KB) | DOI: 10.22146/bkm.40475

Abstract

Latar belakang: Riskesdas 2007, 2013 dan 2018 menunjukkan Penyakit Tidak Menular di Sulawesi Utara menduduki peringkat 10 besar di tingkat nasional. Untuk mengetahui faktor yang menyebabkan tingginya Penyakit Tidak Menular di Sulawesi Utara, maka diperlukan studi jangka panjang tentang prevalensi, dan komorbiditas penyakit metabolik dengan lebih rinci. Penelitian ini bertujuan untuk melihat prevalensi dan komorbiditas penyakit tidak menular di kota Tomohon. Metode: Kami menggunakan data dari Dinas Kesehatan kota Tomohon dalam kurun waktu sembilan tahun terakhir untuk melihat pola perubahan penyakit selama periode tersebut. Kami juga mencari data dari dua Rumah Sakit di kota Tomohon dan salah satu Puskesmas di Tomohon untuk melihat apakah ada persamaan pola kejadian penyakit. Untuk membandingkan data sekunder, kami melakukan survei prevalensi penyakit tidak menular secara langsung ke 630 orang dengan rentang usia antara 17-91 tahun yang mewakili 25% populasi masyarakat tersebut. Hasil: Dari penelitian ini kami menemukan (1) Hipertensi, arthritis dan penyakit sendi, dan diabetes mellitus konsisten menjadi penyakit metabolik utama selama 9 tahun terakhir. (II) Pola yang sama juga terlihat pada laporan Rumah Sakit dengan tambahan penyakit yang berhubungan dengan jantung, stroke dan penyakit ginjal. (III) Data dari puskesmas juga menunjukkan hipertensi, diabetes mellitus dan arthritis menjadi penyakit metabolik utama dengan tambahan hiperurisemia. (IV) Survei secara langsung menunjukkan hiperurisemia, hipertensi, hiperkolesterolmia, gout arthritis dan diabetes mellitus merupakan 5 penyakit metabolik terbanyak pada populasi tersebut. Selain itu, kami juga menemukan komorbiditas penyakit metabolik dari data Puskesmas dan survei secara langsung. (I) Puskesmas menunjukkan hipertensi dan kormobiditasnya menempati posisi pertama komorbiditas penyakit metabolik. (II) Data survei secara langsung juga menunjukkan pola yang sama dengan data Puskesmas. Simpulan: Menurut data keempat sumber data yang kami kumpulkan, tiga penyakit metabolik utama kota Tomohon adalah hipertensi, diabetes mellitus dan penyakit persendian.
Hyperurisemia dan Hubungan antara Asam Urat Darah Dengan Gula Darah Sewaktu dan IMT pada Komunitas Etnik Asli di Halmahera Utara Fiktor I. Boleu; Jubhar C. Mangimbulude; Ferry F. Karwur
Jurnal Ilmu Kesehatan Masyarakat Vol. 9 No. 2 (2018): Jurnal Ilmu Kesehatan Masyarakat
Publisher : Association of Public Health Scholars based in Faculty of Public Health, Sriwijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (629.072 KB) | DOI: 10.26553/jikm.2018.9.2.96-106

Abstract

Latar Belakang: Studi hiperurisemia pada masyarakat dengan latar-belakang etnik tertentu di Indonesiamenarik dipelajari karena selain terkait dengan sejumlah indikator/penyakit metabolik tetapi juga karenakeunikan budaya dan kontribusi genetik yang mungkin signifikan memberi pengaruh. Penelitian ini bertujuanuntuk mengetahui prevalensi hiperurisemia dan melihat hubungannya dengan indikator metabolik lain,khususnya kadar gula darah sewaktu (GDS) dan indeks massa tubuh (IMT) pada komunitas etnik asli diHalmahera Utara.Metode: Sebanyak 240 responden dari 4 komunitas etnik asli di Halmahera Utara diikutsertakan dalampenelitian ini. Penentuan responden (etnik asli) melalui seleksi acak. Penelusuran responden dilakukandengan mengidentifikasi marga yang mewakili nama-nama keluarga pada masing-masing etnik asli diHalmahera Utara. Data dianalisis menggunakan uji statistik Mann Whitney dan Spearman correlation.Hasil Penelitian: Prevalensi hiperurisemia tergolong tinggi, yakni 60% (pria 50,83% dan wanita 69,17%).Sebaliknya, prevalensi hiperglikemia lebih rendah sebesar 1,25% (pria 1,67% dan wanita 0,83%). Prevalensiberat badan lebih (overweight) dan obese adalah berturut-turut 29,17% dan 12,50%; pria 30% dan 11,67%;serta, wanita 28,33% dan 13,33%. terdapat korelasi positif namun tidak nyata antara kadar asam urat danGDS (r=0,082, ρ=0,207), dan terdapat korelasi negatif tidak nyata antara kadar asam urat dan IMT pada populasi etnik (r=-0,047, ρ=0,468). Hubungan antara kadar gula darah dan IMT pada keseluruhan data etnikmenunjukkan hubungan positif dan nyata (r=0,176, ρ=0,006).Kesimpulan: Prevalensi hiperurisemia (dan berat badan lebih) pada etnik-etnik di Halmahera tergolongsangat tinggi. Secara statistik, tidak terdapat hubungan antara nilai kadar asam urat dengan kadar GDS,demikian pula antara kadar asam urat dengan IMT. Terdapat korelasi positif nyata antara nilai IMT dankadar GDS.Kata Kunci: IMT, asam urat, gula darah sewaktu, halmahera utara
Prediksi Aspek Evolusi Xantofil pada Exiguobacterium Sp. yang Berasosiasi dengan Halimeda Macroloba, Hasil Isolasi dari Perairan Pulau Menjangan Kecil, Karimunjawa Wiwik Astuti; Ocky Karna Radjasa; Ferry Fredy Karwur; Ferdy Semuel Rondonuwu
Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek) 2016: Prosiding SNPBS (Seminar Nasional Pendidikan Biologi dan Saintek)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (698.617 KB)

Abstract

Xantofil merupakan oksikarotenoid yang memiliki kemampuan sebagai fotoprotektor, sehingga merupakan senyawa antioksidan yang potensial. Sebarannya yang luas dari tumbuhan tingkat tinggi hingga organisme tingkat rendah, termasuk pada bakteri, menyebabkan xantofil mudah didapat, terlebih lagi dengan sifat kepolarannya, membuat pigmen oksikarotenoid ini relatif mudahuntuk diisolasi dari senyawa karoten lain. 3 jenis xantofil, yaitu dinosantin, P457, dan diadinokrom yang teridentifikasi dari Exiguobacterium sp. MK_HM, bakteri yang berasosiasi dengan karang Halimeda macroloba, hasil isolasi dari perairan Pulau Menjangan Kecil, Karimunjawa, memiliki kesamaan dengan xantofil yang dihasilkan oleh beberapa Dinoflagellata. Hal ini dimungkinkan karena efek asosiasi sekunder yang dilakukan inangnya, Halimeda macroloba dengan Dinoflagellata tertentu.
Merokok dan Oksidasi DNA Fitria, Fitria; Triandhini, R.I.N.K Retno; Mangimbulude, Jubhar C.; Karwur, Ferry Fredy
Sains Medika : Jurnal Kedokteran dan Kesehatan Vol 5, No 2 (2013): July-December 2013
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (368.856 KB) | DOI: 10.30659/sainsmed.v5i2.352

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Cigarette smoke consists of a mix of chemical substances in the form of gases and dispersed particles. Recently, more than 4000 compounds presented incigarette smoke have been isolated. Most of these compounds are toxic to our body’s cells. Toxic gases including carbon monoxide (CO), hydrogen cyanide(HCN), nitrogen oxides, and volatile chemicals such as nitrosamines, formaldehyde are found in in cigarette smoke. besides toxic compounds, cigarettesmoke also containsfree radicalsincluding peroxynitrite, hydrogen peroxide, and superoxide. These free radicals may accelerate cellular damage due tooxidative stress. Targets od free radical attacks include DNA, protein and lipids. The harmful chemicals in form of gases and volatile substances in cigarettescause multiple genetic mutations. the combination of genetic mutations and DNA damage lead to genetic instability and it may cause cancer. OxidativeDNA damage caused by cigarette smoke can be identified with the presence of 8-oxoguanosine used as one of the biomarkers for oxidative DNA damage.Increased concentration of 8-oxoguanosine in DNA has an important role in carcinogenesis and triggers tumor cells. both active and passive smokers havebeen reported to have an elevated concentration of 8-oxoguanosine in their lung tissue and peripheral leukocytes as well as for passive smokers. This paperprovide informations and understanding of the effects of smoking on the genetic stability, especially in the DNA molecule.
Effect of Vitamin E Tocotrienol and Its Combination with Ascorbic Acid to Types of Leukocytes White Rat (Rattus norvegicus L.) Lestariningrum, Nur Auliani; Karwur, Ferry Fredy; Martosupono, Martanto
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 4, No 1 (2012): Januari-Juni 2012
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (278.87 KB) | DOI: 10.30659/sainsmed.v4i1.384

Abstract

Background: Immunity is not separated from the role of leukocytes with various types and functions. Tocotrienol is one of the vitamin E group of compounds with antioxidant properties which to play an important role in cell repair. The aims to determine how much of the effect of vitamin E tocotrienols and its combination with ascorbic acid on the types of leukocytes.Design and Method: Preparation of blood lear dosage edge is a technique used to determine the effect of treatment between types of leukocytes. The design of experiment was conducted with three treatment that feed intake vitamin E tocotrienols and ascorbic acid and their combination with the control and 3 repetitions. Quantitative data leukocyte counts obtained by calculating the percentage of each type of leukocytes in each treatment group and the mean of the data obtained compared with normal leukocyte counts. In addition, the data is processed by the leukocyte counts of variance test using a completely randomized design (CRD) and BNT level of 5% to determine the differences between treatments.Result: The administration of vitamin E tocotrienols and its combination with ascorbic acid influenced significantly (P> 0.05) to increase the neutrophil are 31.66% and 33.66%, 24.33% and 22.33% respectively, when compared with controls. On the other hand, there is a decrease in the percentage of lymphocytes are 26.66% and 29.16%, 19.50% and 17.00% respectively, when compared with controls. Vitamin E tocotrienols and combined with ascorbic acid did not give significant effect (P <0.05) the percentage of eosinophils, basophils and monocytes.Conclusion: The administration of vitamin E tocotrienols and its combination with ascorbic acid to give effect to the increase in neutrophils (Sains Medika, 4(1):46-56).
The Polyphenolics and Health Effects of Pomegranate Nge, Sonya Titin; Martosupono, Martanto; Karwur, Ferry Fredy
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 6, No 1 (2015): January-June 2015
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1505.69 KB) | DOI: 10.30659/sainsmed.v6i1.342

Abstract

Pomegranate (Punica granatum L.) is a useful fruit which mostly consumed as fresh fruit and can also be used as a various of processed products. Reports proved pomegranate were beneficial to health. Polyphenolic compounds in pomegranate especially ellagitannin (hydrolyzed), anthocyanins, gallotannin,and ellagic acid can maintain oral hygiene, healthy skin from the effects of free radicals caused by UV radiation, has the ability to synthesize cholesterol, destroying free radicals in the human vascular system and can prevent prostate cancer. In vitro and in vivo test has shown the fruit is acting as anti diabetic drug, and hypolipidemic, anticarcinogenic, antibacterial, anti inflamation, and antiviral. This review presenting an overview about the bioactive compound contents, physiological and health function of the fruit.
The level of Anxiety in Cervical Cancer Patients of Lower Socioeconomic Status Receiving Chemoteraphy in RSUD Dr. Moewardi Yolanda, Albina Eva; Karwur, Ferry Fredy
Sains Medika : Jurnal Kedokteran dan Kesehatan Vol 5, No 2 (2013): July-December 2013
Publisher : Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1185.048 KB) | DOI: 10.30659/sainsmed.v5i2.344

Abstract

Chemotheraphy for cervical cancer can result in physical and psychological side effects. One of the physical effects is anxiety. This study aimed at identifyingthe level of anxiety in cervical cancer patients of lower socioeconomic status receiving chemotherapy. The anxiety assessment was based on the physicaland psychological quetionnaire (HRS-A) with a guided interview with 40 patients of RSUD Dr. Moewardi. The data from the respondents were tabulatedand analyzed using pivot table of Microsoft Ecxel. The result showed that 40% of the respondents had anxiety symtoms, 30% had a mid anxiety and20% had a medium anxiety and 10% had a severe anxiety. Patients with a personal budget tend to have a higher anxiety compared with those who had agovernment health insurance (JAMKESMAS/Public Health Coverage Insurance). There had been several concerns among the patients including 1) thefear of side effect of chemotheraphy, 2) pessimism of the treatment outcome and the thought of death, 3) inconvenience of regular check for chemoteraphyto hospital and concern about the children and family. The level of anxiety varied among respondents. A lower socioeconic status, lower level of educationand the local wisdom of ‘nrimo’ were responsible for the abcence or lower level of anxiety symptoms in some patients.
Konsumsi, Status Gizi, Dan Profil Kimiawi-Klinis Mahasiswa UKSW Etnis Dayak Ngaju Ferry Fredy Karwur; Venti Agustina; Desi Desi; Leviano Leviano
Jurnal Keperawatan Muhammadiyah Vol 5 No 1 (2020): JURNAL KEPERAWATAN MUHAMMADIYAH
Publisher : UNIVERSITAS MUHAMMADIYAH SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jkm.v5i1.4241

Abstract

Background: Nutrition issues in students mostly happen is a life changes phase that affected by lifestyle, so it could affected the behavior that tend to be unhealthy such as smoking, alcohol consumption, hyper-consumption, lack of physical activities and sleepless. This Unhealthy lifestyle potentially caused disease such as metabolic disorders. Therefore this research aim to find out the consumptions, nutritional status and chemical clinical profile and it correlation between nutritional status, anthropometry with chemical/clinical variable in UKSW students with Dayak ngaju ethnic background. This research used cross sectional observational design. Method: The number of respondents were 30 dayak ngaju ethnic students who lived in Salatiga. Data collection techniques using anthropometry measurements, chemical/clinical examination. Food frequency and food recall. Results: The result of anthropometry measurement and metabolic the 30 students showed, underweight 1 respondent (3,3 %), overweight 4 respondent (13,3%) low diastolic pressure (33,3 %), uric acid levels of 30 students is normal (100 %). 3 students with high cholesterol levels (10 %) and 6 students with high momentary glucose levels (20 %). Students nutritional intake using food recall 24 hours showed average energy consumption ±1527.44 kcal, protein ±51.09 gr, Fat ±46.27 gr, carbohydrate ±238.63 gr. Fulfillment of nutrient intake by category adequacy mostly fit in either category, but there were respondents who fall into the category of medium and light the deficit of protein (10%; 0% of respondents), carbohydrate (3.3%; 3.3% of respondents). The Pearson correlation test shows that there is a correlation between cholesterol and supraliaca with a p-value of 0.002 (p≤0.05).
KAROTENOID PADA ALGAE: KAJIAN TENTANG BIOSINTESIS, DISTRIBUSI SERTA FUNGSI KAROTENOID: Literature Review Merdekawati, Windu; Karwur, Ferry F.; Susanto, A. B.
Bioma Vol. 13 No. 1 (2017): Bioma
Publisher : LPPM Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1014.652 KB) | DOI: 10.21009/Bioma13(1).3

Abstract

ABSTRAK Karotenoid terdistribusi pada archaea, bakteri, jamur, tumbuhan, hewan serta algae. Karotenoid dihasilkan dari komponen isopentenyl pyrophosphate (IPP) yang mengalami proses secara bertahap untuk membentuk beragam jenis karotenoid. Terdapat dua kelompok karotenoid yaitu karoten dan xantofil dengan berbagai jenis turunannya. Struktur kimia pada karotenoid algae yaitu allene, acetylene serta acetylated carotenoids. Algae mempunyai karotenoid spesifik yang menarik untuk dipelajari. Setiap kelas algae mempunyai komposisi karotenoid yang berbeda. Untuk memahami tentang karotenoid algae perlu diketahui jalur biosintesisnya serta enzim yang berperan di dalamnya. Karotenoid terdistribusi pada membran tilakoid sesuai dengan fungsinya dalam fotosintesis. Kata kunci: algae, karotenoid, biosintesis, fukoxantin, LHC, fotosintesis