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Journal : Health Notions

The Effect of Sodium Fluoride Administration on IL-1β and TNF-α Expression on Orthodontic Teeth Movement Rina Sutjiati; Erna Sulistyani; Leliana Sandra Deviade Putri; Rudy Joelijanto; Herniyati Herniyati; Dwi Prijatmoko; Adik Wulandari; Dani Agam Rahmadianto
Health Notions Vol 6, No 3 (2022): March
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn60304

Abstract

Relapse in post orthodontic treatment is common in the community because resorption in the pressure side occurs excessively due to teeth being moved with an orthodontic device. Excessive resorption can be inhibited by using NaF which has been shown to inhibit osteoclast activity, thereby reducing osteoclast numbers. The purpose of this study was to analyze the effect of NaF administration on IL-1β and TNF-α expression of osteoclast in orthodontic teeth movement. The research used experimental-quantitative research type applying Randomized Posttest Only Control Group Design, by selecting the experimental group and the control group randomly. Animal model using 16 male Wistar rats given orthodontic force using NiTi closed coil spring adjusted to give 10 grams/cm2 of mechanical strength, were applied to the palatal in the maxillary incisors of the Wistar rat teeth. Rats were divided into two groups, the control group (C group) and treatment group (T group) given topical NaF application (11.75 ppm). Immunohistochemical examination was performed to calculate IL-1β and TNF-α expression on osteoclasts on the 7th day and 14th day. The administration of NaF reduces IL-1β and TNF-α osteoclast’s expression both on the 7th day (p <0.05) and 14th day (p <0.05). Data were tested by the Kolmogorov-Smirnov test, Levene test and the difference tested Annova followed by LSD (p <0.05). Topical administration of NaF application to the gingival sulcus of male Wistar rats in orthodontic tooth movement can reduce the number of osteoclasts that express IL-1β in the alveolar bone in the pressure area. Topical administration of NaF application to the gingival sulcus of male Wistar rats in orthodontic tooth movement can reduce the number of osteoclasts that express TNF-α in the alveolar bone in the pressure region. Decreased number of osteoclasts expressing IL-1β and TNF-α significantly occurred on the 7th day and 14th day. Keywords: IL-1β; TNF-α; NaF; osteoclast; orthodontic teeth movement
The Infulence of Various Food Intake on Body Fat Distribution among Young Healthy Population Dwi Prijatmoko; Sulistiyani Sulistiyani; Dyah Setyorini; Hestieyonini Hadnyanawati; Elyda Akhya Afida Misrohmasari; Anisa Nur Syabila
Health Notions Vol 6, No 8 (2022): August
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn60803

Abstract

Food intake is the amount of food obtained by the body via daily food consumption that consists of energy, carbs, fat, and protein. The distribution of fat will be affected by an imbalance in food consumption. The distribution of body fat is classified as either android or gynoid obesity. Someone who has abdominal obesity is more likely to develop metabolic syndrome. This study aims to determine the influence of food intake on fat distribution in dental student of Faculty of Dentistry, University of Jember. Analytic observational research methods were applied in this study. The population comprised of 109 students from the Faculty of Dentistry at the University of Jember. The research procedures comprised instructing, measuring height, weight, the waist-hip circumference ratio, completing the food intake measurement sheet based on 24 hours food recall, data conversion, and data entry. The influence of food intake on fat distribution was determined using logistic regression data analysis. The results revealed that food intake had an effect on fat distribution. The male group's effect was energy, while the female group's influence was carbohydrates and fat, according to the study's findings. Food consumption has a substantial impact on the distribution of body fat among dental students at the Faculty of Dentistry Keywords: food intake; fat distribution; abdominal obesity; waist-hip ratio