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All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Global Medical and Health Communication Biology, Medicine, & Natural Product Chemistry Paediatrica Indonesiana Logista: Jurnal Ilmiah Pengabdian Kepada Masyarakat Acta Biochimica Indonesiana SRIWIJAYA JOURNAL OF MEDICINE Majalah Kedokteran Andalas Abdimas Galuh: Jurnal Pengabdian Kepada Masyarakat Sricommerce: Journal of Sriwijaya Community Services Jurnal Sains Kebidanan Jurnal Pengabdian Masyarakat: Humanity and Medicine Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Conferences of Medical Sciences Dies Natalis Jurnal Pengabdian Pada Masyarakat Kreativitas Pada Pengabdian Masyarakat (Krepa) Musyawarah: Jurnal Pengabdian Masyarakat
Athiah, Medina
Bagian Biokimia Dan Kimia Medik Fakultas Kedokteran, Universitas Sriwijaya, Palembang, Indonesia
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UNLOCKING THE ANTI-HYPERURICEMIA POTENTIAL OF Arcangelisia flava STEM: AN IN VIVO STUDY IN HYPERURICEMIC RATS Fatmawati; Attallah Perdana Akbar; Medina Athiah; Eka Handayani Okhtarina
Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Vol. 12 No. 3 (2025): Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Univers
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32539/jkk.v12i3.637

Abstract

Hyperuricemia is a condition of increased uric acid levels in the blood that can trigger gout and other metabolic disorders. Conventional therapies such as allopurinol are effective, but have side effects, so safer natural alternatives are needed. Arcangelisia flava, a traditional medicinal plant, is known to contain bioactive compounds with anti-inflammatory and antioxidant potential. This study aims to evaluate the anti-hyperuricemic effect of ethanol extract of A. flava stems in vivo in potassium oxonate-induced rats. Rats were divided into control groups, hyperuricemia models, and treatments with extract doses of 100, 200, and 400 mg/kg BW. Uric acid levels were measured enzymatically before and after treatment. The results showed that A. flava extract significantly reduced uric acid levels (p=0.000), especially at a dose of 400 mg/kg BW which reduced uric acid levels by 74.17%. These findings support the potential of A. flava as a natural anti-hyperuricemic agent.
Stress levels and menstrual cycles in high school adolescents Saldinar, Alena Briliantyas; Athiah, Medina; Hasanah, Yulisnawati; Nurwanny, Raissa; Aditiawati, Aditiawati
Paediatrica Indonesiana Vol. 65 No. 4 (2025): July 2025
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi65.4.2025.325-30

Abstract

Background Around 15.5 million (34.9%) adolescents in Indonesia experience stress. Most of the stress in adolescents comes from internal and external academic demands. One of the negative impacts of stress is the disruption of hormonal mechanisms in the female reproductive system, which can affect the menstrual cycle. Objective To analyze the relationship between stress level and menstrual cycle in adolescent girls aged 15 - 17 years who have menses  ≥ 2 years. Methods This study used primary data from instruments such as the Depression Anxiety Stress Scale (DASS 42) questionnaire modified by Damanik and the menstrual cycle questionnaire by Aldiba filled on Google forms by 1,565 adolescents from four high schools in Palembang City. We also excluded adolescents with conditions that could potentially bias the study, such as endocrine diseases (pituitary tumors and Cushing's syndrome), athletes with intensive physical activity, use of hormonal drugs, and abnormalities in nutritional status. Results A total of 281 of 961 respondents who met the inclusion criteria were randomly selected through a stratified proportional random sampling method. Of those who reported experiencing stress, 27% experienced moderate stress. The majority of subjects experienced menstrual cycle disorders (55.5%). Adolescents with moderate stress level and above had a greater percentage of menstrual cycle disorders compared to adolescents who did not experience stress (P=0.039). Severe levels of stress were significantly associated with menstrual cycle irregularities (P=0.025) Conclusion Stress levels are significantly associated with menstrual cycle irregularities among high school adolescents in Palembang City.
ANALISIS KADAR PROTEIN ASI PERAH IBU MENYUSUI BERDASAR INDEKS MASSA TUBUH Subandrate, Subandrate; Santosa, Dorothy Eunike; Oswari, Liniyanti D; Oktharina, Eka Handayani; Sinulingga, Sadakata; Athiah, Medina
Jurnal Sains Kebidanan Vol. 6 No. 1 (2024): MEI 2024
Publisher : POLTEKKES KEMENKES SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jsk.v6i1.11083

Abstract

Salah satu komponen makronutrien ASI ialah protein yang sangat bermanfaat dalam pertumbuhan dan perkembangan bayi. Faktor ibu, bayi, dan fisiologis memengaruhi kadar protein dalam ASI. Salah satu faktor ibu, yaitu indeks massa tubuh (IMT). Penelitian ini dilakukan dengan tujuan untuk mengetahui pengaruh IMT terhadap kadar protein pada ASI perah. Desain penelitian ini adalah analitik observasional dengan pendekatan cross sectional yang dilakukan di Laboratorium Kimia Dasar Kedokteran, Fakultas Kedokteran, Universitas Sriwijaya. Penelitian ini menggunakan 63 sampel ASI perah dari ibu menyusui di kota Palembang berusia 20-35 tahun dengan bayi berusia 1-6 bulan. Sampel ASI perah berjumlah 63 tersebut terbagi menjadi 2 kategori, yaitu 30 sampel ASI ibu dengan IMT normal dan 33 sampel ASI ibu dengan IMT gemuk dan obesitas. Pengukuran protein menggunakan metode Lowry dan data dianalisis dengan uji Mann-Whitney. Rata-rata kadar protein ASI perah pada ibu dengan IMT normal yaitu 6,35±5,78 mg/mL dan rata-rata kadar protein ASI perah pada ibu dengan IMT gemuk dan obesitas yaitu 8,64±3,70 mg/mL. Uji Mann-Whitney menunjukkan nilai p=0,03 (p< 0,05). Pada ibu dengan IMT gemuk dan obesitas, peningkatan porsi dan frekuensi makan, meningkatkan asupan asam amino sehingga meningkatkan kadar protein dalam ASI perah. Kesimpulannya, IMT ibu berpengaruh terhadap kadar protein pada ASI perah.
Co-Authors Aditiawati Aditiawati, Aditiawati Adiyatma Putra Mahardika Agustiarini, Vitri Agustine, Vania Annes C. Adma Apriani, Elsa Fitria Ardesy Melizah Kurniati Ardesy Melizah Kurniati Attallah Perdana Akbar Aulia Firdha Tariza Dwirini Retno Gunarti Eka Handayani Okhtarina Ella Amalia, Ella Ellla Amalia Fatmawati Fatmawati Fatmawati Fatmawati Fatmawati Fertilita, Soilia Fifa Argentina Heni Yusnita, Heni Hermansyah Hertanti Indah Lestari, Hertanti Indah Irfannuddin Irfannuddin Izzah, Puspita Nurul Karimudin, Yos Liniyanti D. Oswari M Fitra Romadhon M. Dias A. Monanda M. Hafizh Arrafi M. Hafizh Arrafi M. Nadhif Prasetyo M. Nadhif Prasetyo Marieska Verawaty Muhammad Irsan Saleh Mulyani, Laida Neti Nita Parisa Nurwanny, Raissa Oktariana, Desi Oktharina, Eka Handayani Oswari, Liniyanti D Putri Maya Sari Raneo, Agung Putra Rasyid, Riana Sari Puspita Rini Yana Sadakata Sinulingga Safyudin Safyudin Safyudin Safyudin Safyudin Saldinar, Alena Briliantyas Salni Santosa, Dorothy Eunike Saputri, Nyimas Dewi Murnila Siti Sarahdeaz Fazzaura Putri Subandrate Susilawati Susilawati Syarif Husin Tanta, Yudhi Veny Larasati Windi Indah Fajar Ningsih Yulisnawati Hasanah Yulistiana, Sisca Zanaria, Rima Zikra, Muhamad Zulfadli, Muhammad