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STUDY OF POTENTIAL DRUG INTERACTIONS IN MIGRAINE PATIENTS WITH COMORBIDITIES AT TANJUNGPURA UNIVERSITY HOSPITAL PONTIANAK Yuandini, Neisya; Susanti, Ressi; Kusharyanti, Indri
Journal Pharmacy Of Tanjungpura Vol 2, No 2 (2025): APRIL
Publisher : Universitas Tanjungpura

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Abstract

Migraine patients have the potential of drug interactions due to polypharmacy-related comorbidities. Drug interactions can trigger therapeutic failure because they can affect drug effectiveness. This study aims to assess interacting drugs as well as the type and severity of drug interactions in migraine patients at Tanjungpura University Hospital Pontianak. This study was a non-experimental study with a descriptive cross-sectional design. Data were collected retrospectively through 25 medical records of migraine patients in 2022-2023 with a purposive sampling technique. The results show that drugs with potential interactions in migraine patients with comorbidities are ergotamine+caffeine, ibuprofen, metampirone+diazepam, diclofenac sodium, paracetamol, valproic acid, propranolol, and amitriptyline. The types of potential drug interactions found are pharmacodynamic (39.62%), pharmacokinetic (30.18%), and unknown (30.18%), with moderate (62.26%), minor (30.18%), and major (7.54%) severity. This study conclude that ergotamine+caffeine is the drug with the most potential interactions. The most potential interactions are pharmacodynamic interactions and moderate interactions.
EFEKTIVITAS BIAYA PENGGUNAAN ANTIBIOTIK PADA PASIEN PNEUMONIA BALITA DI INSTALASI RAWAT JALAN DI RUMAH SAKIT BHAYANGKARA ANTON SOEJARWO PONTIANAK Jagad, Galuh Sekar; Kusharyanti, Indri
Journal Pharmacy Of Tanjungpura Vol 1, No 1 (2023): Oktober
Publisher : Universitas Tanjungpura

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Abstract

Pengobatan infeksi pneumonia dengan terapi antibiotik yang tepat dan efektif akan menentukan keberhasilan pengobatan serta menghindari hal-hal yang merugikan seperti biaya pengobatan mahal. Upaya yang dilakukan untuk mengatasi permasalahan biaya ialah dengan studi farmakoekonomi. Tujuan dari penelitian ini adalah mengidentifikasi profil penggunaan antibiotik dan menganalisis antibiotik yang paling cost-effective pada pasien balita pneumonia rawat jalan di RS Bhayangkara Anton Soejarwo Pontianak. Metode yang digunakan merupakan non eksperimental dengan rancangan penelitian deskriptif data yang diambil secara retrospektif yaitu berupa data rekam medik pasien pneumonia rawat jalan di RS Bhayangkara Anton Soerjarwo pada periode Januari "“ Desember 2022 dengan jumlah 72 sampel.   Hasil penelitian ini terbanyak rentang usia 1-5 tahun (63,89%) dan lebih banyak berjenis kelamin laki-laki (62,50%) dibandingkan perempuan (37,50%) dan efektivitas terapi tunggal (76,92%) efektivitas terapi kombinasi (85,71%) Kesimpulan penelitian ini yaitu profil penggunaan antibiotik pada pasien pneumonia balita yang di rawat jalan di RS Bhayangkara Anton Soejarwo Pontianak ialah ampicillin (40,28%), amoxicillin (16,67%), cefixime (23,61%), cefadroxil (9,72%)   dan kombinasi ampicillin+ cefixime (9,72%)   dan berdasarkan nilai ACER, maka dapat disimpulkan bahwa antibiotik tunggal Rp.19.858,-   lebih cost-effective daripada antibiotik kombinasi Rp.42,818,- dan diantara terapi antibiotik tunggal ialah ampicillin dengan nilai ACER Rp. 13.395,-   dan nilai ICER dari ampicillin ke cefixime Rp.1.581,35,- sedangkan nilai ICER ampicillin ke ampicillin+cefixime Rp.2.654,86,-
Penerapan Swamedikasi Obat Modern dan Obat Tradisional Penyakit Gastritis pada Kader Kesehatan SMAN 12 Pontianak: Implementation of Self-Medication Practices Using Modern and Traditional Medicines for Gastritis Among Health Cadres at SMAN 12 Pontianak Sinaga, Clara Ritawany; Kusharyanti, Indri; Aprianti, Indah
Jurnal Pengabdian Kepada Masyarakat: Kesehatan Vol. 5 No. 4 (2025): Desember
Publisher : Sekolah Tinggi Ilmu Kesehatan Notokusumo Yogyakarta

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Abstract

Abstrak: Gastritis merupakan salah satu gangguan pencernaan yang sering dialami oleh remaja terutama akibat pola makan yang tidak teratur dan stres. Salah satu strategi yang dapat dilakukan untuk mengatasi gejala gastritis ringan adalah melalui pengobatan sendiri. Namun, rendahnya tingkat pengetahuan remaja mengenai penggunaan obat modern dan tradisional untuk gastritis dapat meningkatkan risiko terjadinya medication error. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pemahaman mahasiswa sebagai kader kesehatan mengenai pengobatan sendiri gastritis secara rasional melalui edukasi berbasis terapi farmakologi dan nonfarmakologi. Kegiatan dilaksanakan di SMAN 12 Pontianak dengan melibatkan 25 siswa yang tergabung ke dalam kader kesehatan. Metode pelaksanaan meliputi edukasi klasikal, diskusi, penggunaan alat demonstrasi obat, dan pengisian angket pretest dan posttest untuk mengukur peningkatan pengetahuan. Terjadi peningkatan nilai rata-rata pengetahuan siswa dari 58,8 (pretest) menjadi 77,6 (posttest). Selain itu, tingkat kepuasan terhadap kegiatan mencapai 87,2% yang menunjukkan bahwa metode edukasi diterima dengan baik dan dinilai bermanfaat. Pendidikan pengobatan sendiri gastritis berbasis farmakologi dan bahan alami secara signifikan meningkatkan pengetahuan kader kesehatan siswa. Program ini efektif dan dapat digunakan sebagai model untuk pendidikan serupa di lingkungan sekolah lainnya.   Abstract: Gastritis is one of the most common digestive disorders experienced by adolescents, primarily due to irregular eating habits and stress. One strategy to manage mild gastritis symptoms is self-medication. However, the low level of adolescent knowledge regarding the use of modern and traditional medicines for gastritis can increase the risk of medication errors. This community service activity aimed to enhance students' understanding, as health cadres, of rational self-medication for gastritis through education based on pharmacological and non-pharmacological therapy. The program was conducted at SMAN 12 Pontianak, involving 25 students who serve as school health cadres. The implementation methods included classical education sessions, discussions, the use of drug demonstration tools, and the administration of pre- and post-test questionnaires to measure knowledge improvement. There was an increase in the average student knowledge score from 58.8 (pre-test) to 77.6 (post-test). In addition, the satisfaction rate with the activity reached 87.2%, indicating that the educational methods were well-received and considered beneficial. Pharmacology- and natural product-based self-medication education significantly improved the knowledge of student health cadres. This program proved to be effective and could serve as a model for similar educational initiatives in other school settings.
UJI AKTIVITAS ANTI JAMUR SEDIAAN SERUM EKSTRAK ETANOL DAUN PACAR (Impatiens balsamina L.) TERHADAP JAMUR Candida albicans SECARA IN VITRO Kusharyanti, Indri; Pratiwi, Liza; Anjani, Ayu Paramitha
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 11 No 1 (2026): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v11i1.3009

Abstract

The normal flora on the scalp that can cause dandruff when excess oil is produced is Candida albicans. Chemical antifungal treatments for dandruff often cause side effects such as hair loss and headaches. Garden balsam leaves, which contain antifungal compounds like flavonoids, saponins, and alkaloids, can be extracted and formulated into hair serum as a natural alternative. This study aims to analyze the physical properties of the extract and serum from water henna leaves and evaluate their antifungal activity against Candida albicans. The evaluation involved physical property tests and in vitro disc diffusion using 2% ketoconazole shampoo as a positive control and serum without extract as a negative control. Tested concentrations were 1%, 3%, and 5%. Standardization of the extract showed a thick, dark brown liquid with a characteristic odor, a yield of 36.66%, water-soluble extract content of 78.66%, ethanol-soluble extract content of 70.09%, and moisture content of 2.51%. The serum showed increased color intensity, spreadability (4.63–5.3 cm), adhesiveness (3.49–41.91 seconds), pH (5.74–8.78), and viscosity (1016.6–1417.6 cPs). No inhibition zones were observed in the extract, serum, or negative control, while the positive control showed a strong inhibition zone of 46.03 mm.