Article Per Year (5 Year)
p-Index From 2020 - 2025
2.096
P-Index
This Author published in this journals
All Journal Jurnal Studi Pemerintahan JURNAL KIMIA SAINS DAN APLIKASI Jurnal Natur Indonesia Pharmaciana: Jurnal Kefarmasian Sainteknol : Jurnal Sains dan Teknologi Gadjah Mada International Journal of Business agriTECH Jurnal Kebijakan dan Administrasi Publik Al-Kimia Jurnal Bioedukatika Indonesian Journal of Chemistry Chemistry Indonesian Journal of Chemical Research Dalton : Jurnal Pendidikan Kimia dan Ilmu Kimia Biota Molekul: Jurnal Ilmiah Kimia Berkala Penelitian Hayati INSECTA: Integrative Science Education and Teaching Activity Journal Molekul: Jurnal Ilmiah Kimia Biodik: Jurnal Ilmiah Pendidikan Biologi Bioma : Jurnal Ilmiah Biologi
Sabirin Matsjeh
Universitas Ahmad Dahlan
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Physics Public Health Social Sciences

Published : 45 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Jurnal Natur Indonesia

 1 
Pemanfaatan Minyak Daun Cengkeh untuk Sintesis 3,4-dimetoksibenzil Sianida sebagai Bahan Dasar Sintesis Isoflavon Alimuddin, Andi Hairil; Matsjeh, Sabirin; Anwar, Chairil; Mustofa, Mustofa
Jurnal Natur Indonesia Vol 15, No 1 (2013)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (144.173 KB) | DOI: 10.31258/jnat.15.1.68-74

Abstract

This research was aimed to utilize eugenol isolated from clove leave oil in the synthesis of isoflavones. Eugenol was usedas a raw material by converting into 3,4-dimethoxybenzyl cyanide through several stages of reactions. These stages weremethylation of eugenol, isomerization of methyleugenol, oxydation of methylisoeugenol, reduction of 3,4-dimethoxybenzaldehyde, halogenation of 3,4-imethoxybenzyl alcohol and nitrilization of 3,4-dimethoxybenzyl chloride to3.4-dimethoxybenzyl cyanide. Methylation of eugenol using dimethylsulfate and NaOH catalyst produced methyleugenolin 93.60% purity. Isomerization of methyleugenol employing base of potassium tertiary butoxide (t-BuOK) in dimethylsulfoxide (DMSO) gave methylisoeugenol with 87.15% yield and 98.10% purity. Oxidation of methylisoeugenol usingpotassium dichromate (K 2 Cr 2 O 7 ) was performed catalyst transfer phase (CTP) system of polysorbate 80 to 83.40% 3.4-dimethoxybenzaldehyde yield and 90.20% purity. Reduction of 3.4-dimethoxybenzaldehyde with sodium borohidrat (NaBH 4 )produced 98% yield. Halogenation of 3,4-dimethoxybenzyl alcohol by SOCl 2 to 3,4-dimethoxybenzyl chloride followed bynitrilisation using sodium cyanide produced 3.4-dimethoxybenzyl cyanide with 83.90% purity after reflux for 20 hours.
Co-Authors Ainun Mardiah Andi Hairil Alimuddin Andi Hairil Alimuddin Andi Hairil Alimuddin Andi Hairil Alimuddin Chairil Anwar Chairil Anwar Chairil Anwar Chairil Anwar Chairil Anwar Chairil Anwar Chairil Anwar Chairil Anwar Damayanti Iskandar Daratu Kusuma Eviana Putri Deni Pranowo Dewi Kumalasari Dwi Siswanta Dwi Siswanta Elfi Susanti V. H. Eti Nurwening Sholikhah Etika Dyah Puspitasari Fika Pita Loka Fikroh, Retno Aliyatul Hanoch J Sohilait HAPSARI, MAHARANI Hardjono Sastrohamidjojo Harno Dwi Pranowo Harno Dwi Pranowo Harno Dwi Pranowo Iqna Yudiyanti Ismiyarto Ismitarto J Stuart Grossert Jefry Presson Jumina Jumina Jumina Jumina Juni Lestari, Tri Tunggal Kapelle, Imanuel B. D. Kartika Sari, Prita Anggraeni KRISDIYATMIKO, KRISDIYATMIKO kusmiyati kusmiyati Kusmiyati kusmiyati La Harimu Lukas Pardosi Meta Permata Putri Mudasir Mudasir Mudasir Mudasir Mudasir Muhammad Idham Darussalam Mardjan Muhammad Idham Darussalam Mardjan Mustofa Mustofa Mustofa Mustofa Mustofa Mustofa Mustofa Mustofa Mustofa Mustofa Mutmainah Mutmainah Nanik Lestari, Nanik Novia Suryani Nuniek Herdyastuti Nuniek Herdyastuti Nurohmah, Beta Achromi Oedjijono Oedjijono Pambudi, Wisnu Puji Lestari Purwati Purwati Puspitasari, Etika Dyah Ratna Dewi Kusumaningtyas Respati Tri Swasono Retno Aliyatul Fikroh Retno Aliyatul Fikroh Retno Ambarwati Rokhima Rostiani S Mursiti Santi Nur Handayani Sari Edi Cahyaningrum Siti Nuryanti Siti Nuryanti Sri Juari Santosa Sri Juari Santosa Susilawati Susilawati Susilawati Susilawati Syarifah Asyura Tri Joko Raharjo Tri Joko Raharjo Tri Redjeki Tutik Dwi Wahyuningsih Winarto Haryadi Winarto Haryadi Yuri Pradika Zulfah Az Zahra