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All Journal Jurnal NERS Indonesian Journal of Cancer JIMKesmas (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) Majalah Obstetri dan Ginekologi Syntax Literate: Jurnal Ilmiah Indonesia The Southeast Asian Journal of Midwifery Pediomaternal Nursing Journal Indonesian Journal of Anesthesiology and Reanimation (IJAR) INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL International Journal of Midwifery Research Indonesian Journal of Cancer Folia Medica Indonesiana
PUNGKY MULAWARDHANA, PUNGKY
Department Of Obstetric And Gynecology, Faculty Of Medicine, Universitas Airlangga, Dr Soetomo Hospital, Surabaya
Humanities Biochemistry, Genetics & Molecular Biology Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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The prognostic role of mitosis index, stage and grade of endometrial cancer in Dr. Soetomo General Academic Hospital Surabaya, Indonesia, in 2018-2020 Umi Choviva, Farida; Sandhika, Willy; Mulawardhana, Pungky
Majalah Obstetri & Ginekologi Vol. 32 No. 2 (2024): August
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mog.V32I22024.74-79

Abstract

HIGHLIGHTS 1. Mitotic index and grade are prognostic factors for endometrial cancer, but both are independent.2. Stage and mitotic index associated with cell proliferation affect the prognosis of endometrial cancer.   ABSTRACT Objective: This study aimed to analyze the correlation between the mitotic index and the stage and grade of endometrial cancer. Materials and Methods: We collected pathology reports of endometrial cancer from the Pathology Laboratory at Dr. Soetomo General Hospital in Surabaya, Indonesia, covering cases diagnosed between 2018 and 2020. A total of 106 cases of endometrial cancer were included in this study. For each case, detailed records of the cancer stage, grade, and mitotic index were recorded. The mitotic index, an indicator of cell proliferation, was quantified, and its correlation with cancer stage and grade was assessed. To determine the strength and direction of these relationships, we performed a Spearman rank correlation statistical analysis for non-parametric data. Results: Our findings indicated a significant positive correlation between the mitotic index and the stage of endometrial cancer. An increase in the mitotic index, reflecting a higher proliferation rate of cancer cells, was associated with a more advanced cancer stage, suggesting that the mitotic index could potentially serve as a prognostic marker for assessing tumor progression in endometrial cancer. However, our analysis revealed no significant correlation between the mitotic index and the histological grade of endometrial cancer, implying that the grade, which typically reflects the differentiation status and morphological characteristics of the tumor cells, is independent of the proliferation rate as measured by the mitotic index. Conclusion: The mitotic index is positively correlated with the stage of endometrial cancer but does not show a correlation with the histological grade. These findings highlight the potential use of the mitotic index in staging endometrial cancer.
DIFFERENCES IN CHANGES IN KNOWLEDGE OF WOMEN ABOUT EARLY DETECTION OF CERVICAL CANCER BETWEEN USING PRESENTATION MEDIA COUNSELING AND LEAFLET COUNSELING Yuliana, Baiq Ade Herna; Purwanto , Bambang; Euvanggelia Dwilda Ferdinandus; Mulawardhana , Pungky
Indonesian Midwifery and Health Sciences Journal Vol. 8 No. 3 (2024): Indonesian Midwifery and Health Sciences Journal, July 2024
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v8i3.2024.300-311

Abstract

Background: Encouraging early detection and prompt treatment of precancerous lesions is the key to preventing cervical cancer in women who are fertile. IVA examinations are used to detect precancerous lesions early on. Thus far, both nationally and at Mojo Health Center, the IVA examination has been achieved. Women of reproductive age may not be as aware of early diagnosis of precancerous lesions as they should be, which could contribute to the low IVA examination achievement. Due to a lack of understanding regarding the early diagnosis of precancerous lesions, women of reproductive age have low awareness. Method: A lecture and leafleting approach were used to conduct this health counseling. This kind of study uses a quasi-experimental pretest-posttest one group design, which is experimental in nature. carried out in Surabaya City at the Mojo Health Center. A straightforward random sampling methodology was used to choose the sample of 84 WUS, who were then split into two groups: the treatment group, which received an intervention counseling lecture style, and the control group, which received a leaflet intervention. A questionnaire was utilized to collect the data, and the Wilcoxon signed rank test was used to evaluate it. Independent Samples Test (p<0.05) and Wilcoxon signed Rank test. Results: The test results showing variations in both groups' knowledge levels produced the result p = 0.000 (p <0.05). P = 0.268 (p>0.05) was the outcome of the test to determine the value of differences in knowledge factors between the treatment group and the control group. Conclusion: There is no difference in WUS knowledge between the lecture method and leaflet media distribution when it comes to counseling, but there is a shift in the outcomes of WUS knowledge about early detection of cervical cancer before and after receiving counseling.
MIDWIFE KNOWLEDGE IN EARLY DETECTION OF CERVICAL CANCER USING VISUAL INSPECTION WITH ACETIC ACID METHOD Sari, Deviati Juwita; Lestari, Pudji; Mulawardhana, Pungky
INTERNATIONAL JOURNAL OF MIDWIFERY RESEARCH Vol. 1 No. 3 (2022): International Journal of Midwifery Research
Publisher : Department of Midwifery, Faculty of Nursing and Midwifery, Institut Ilmu Kesehatan Nahdlatul Ulama Tuban

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47710/ijmr.v1i3.15

Abstract

Knowledge of a midwife in to do VIA examination will influence achievement VIA examination. Study this aim for knowing connection Among education and training status with knowledge midwife in detection early cancer cervix use method Visual inspection with acetic acid (VIA) in Banjarmasin City. Research design this is cross-sectional in 26 Puskesmas in Banjarmasin City March – November 2020 with amount sample as many as 172 respondents, retrieval technique sample use non-probability sampling technique is purposive sampling . Instrument study in the form of questionnaires and reports from the Department of Health. Data analysis is carried out by computerization. A total of 172 respondents obtained part big respondents who have P2B and D3 Midwifery education have knowledge not enough by 61.6% and the majority respondents who have not once follow training have knowledge not enough as much as 67.9%. Statistical test results show no there is connection Among education (p = 0,171) and training status (p = 0,001) with knowledge midwife in detection early cancer cervix with use VIA method. Research results show no there is connection Among education and there connection between training status with knowledge midwife in detection early cancer cervix use VIA method in Banjarmasin City. Training is one the step that becomes consideration in increase performance midwife in detection cancer cervical .
Severe Preeclamptic Patients in The Resuscitation Room of Dr. Soetomo General Academic Hospital Surabaya: A Retrospective Study Firmanto, Neissya Nastiti; Maulydia; Mulawardhana, Pungky; Fitriati, Mariza
Indonesian Journal of Anesthesiology and Reanimation Vol. 4 No. 2 (2022): Indonesian Journal of Anesthesiology and Reanimation (IJAR)
Publisher : Faculty of Medicine-Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijar.V4I22022.62-71

Abstract

Introduction: Preeclampsia is the leading cause of maternal and fetal death. This is an urgency in maternal health, especially in developing countries such as Indonesia. Patients with severe preeclampsia who had critical conditions tend to be admitted to the resuscitation room for assistance from more skilled personnel and more sophisticated technology. Objective: This study aims to determine the complications, treatments, and outcomes of severe preeclampsia patients managed in the resuscitation room at Dr. Soetomo General Academic Hospital from January 1st, 2018 – December 31th 2019. Methods: The method used in this study was retrospective descriptive using medical records and analyzed using Microsoft Excel. Eighty-one samples met the inclusion criteria. Results: The majority of patients were aged 20-35 years (65.43%) and had completed senior high school (88.89%). Most patients were having stage 2 obesity (44.44%) and multigravida (41.97%). A history of preeclampsia and hypertension was not found in the majority of patients. Most patients are diagnosed with late-onset preeclampsia (69.14%). The majority of patients were referred from secondary health facilities (96.30%). The most common complication was pulmonary edema(53.09%). The majority of patients had 2 complications (43.17%) with the most common combinations being eclampsia and HELPP syndrome (13.58%). Intubation is given to the majority of patients (70.37%) and most often in patients with eclampsia (56.14%). Termination of pregnancy by cesarean section is carried out in the majority of patients (72.84%). There were no cases of maternal death in this study. Most of the fetal born had prematurity (70.11%), low birth weight (60%), and asphyxia as assessed by the first minute APGAR score (72.97%) and fifth minute APGAR score (54.05%). Conclusion: The majority of preeclampsia patients with complications in the resuscitation room at Dr. Soetomo General Academic Hospital Surabaya from January 1st 2018-December 31rd 2019 had good maternal outcomes but not the fetal outcome.
Maternal Deaths caused by COVID-19 Infection in the First Year of the Pandemic Wave Akbar, Muhammad Ilham Aldika; Mulawardhana, Pungky; Wardhana, Manggala Pasca; Gumilar, Khanisyah Erza; Raheestyningtyas, Ecccita; Laksana, Muhammad Ardian Cahya; Anas, Jimmy Yanuar; , Ernawati; Joewono, Hermanto Tri; Bachnas, Muhammad Adrianes; Tjokroprawiro, Brahmana Askandar
Folia Medica Indonesiana Vol. 59, No. 2
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Highlights: • These cases of maternal deaths caused by COVID-19 infections illustrated the significant risk factors for maternal mortality during the early phases of the pandemic, while studies had not extensively reported this. • COVID-19 infections increase the risk of maternal and neonatal mortality, with infants having a lower chance of survival even if they are delivered. • Respiratory support, antiviral medications, antibiotics, anticoagulants, and supportive care are the primary treatments for severe COVID-19 in pregnancy. Abstract This article presents seven cases of maternal deaths attributed to COVID-19 during the first year of the pandemic wave. These cases provide insights into the natural progression of COVID-19 in pregnant women who were not vaccinated. This study showed that COVID-19 significantly increased maternal and neonatal mortality and morbidity. All of the patients exhibited symptoms of fever, cough, and dyspnea upon admission to the hospital. They were admitted with elevated respiratory rates (26–32 times/minute) and low oxygen saturation (<95%). Four patients had obesity, while one patient had pregestational diabetes. The COVID-19 diagnosis was established using a rapid antibody or antigen test and chest X-ray, which indicated pneumonia. Medical interventions administered to the patients included antiviral therapy (5 patients), antibiotics (6 patients), and anticoagulants (4 patients). From a total of five babies delivered, four babies were delivered via cesarean section. Two babies were not delivered due to previability and maternal deaths before delivery. The patients passed away within 3–10 days of hospital admission. In conclusion, adequate and early intervention and management of pregnant women infected with COVID-19 are crucial in preventing maternal and neonatal deaths, especially in unvaccinated women.
Co-Authors , Ernawati Aldika Akbar, Muhammad Ilham Alifina Izza Anak Agung Istri Sri Wiadnyani Anas, Jimmy Yanuar Anggray Puspasari Anna Febriani Anny Setijo Rahaju, Anny Setijo Askandar Tjokroprawiro Atmi Marmiati Bachnas, Muhammad Adrianes Budi Utomo Deviati Juwita Sari Deviati Juwita Sari Dyah Erawati, Dyah Ecccita Raheestyningtyas Eccita Rahestyningtyas Ernawati Ernawati Eva Silvia Yahya Fadhilah Sari Faizah, Zakiyatul Ferdinandus, Euvanggelia Dwilda Firda Azizah Firmanto, Neissya Nastiti Fitria Khusnul Khotimah Fitriati, Mariza Fransisca Wiga Alda Maretha Hermanto Tri Joewono INDRA YULIATI, INDRA Jeremia Alvian Wiranata Jimmy Yanuar Anas Khanisyah Erza Gumilar Laksana, Muhammad Ardian Cahya Maulydia Ma’rifatu Ulfa Hidayati Mega Lestari Muhammad Adrianes Bachnas Muhammad Hafiz Nila Kurniasari Pudji Lestari Purwanto , Bambang Raheestyningtyas, Ecccita Reny I’tishom Reza Wangsanagara S.Pd. M Kes I Ketut Sudiana . Samantha, Ines Samsriyaningsih Handayani Sari, Deviati Juwita SOEHATNO - SOEHATNO -, SOEHATNO Sudaryanti, Lestari Tomy Lesmana Tri Wulanhandarini Tsalitsa Fajrina Jauhari Umi Choviva, Farida Vicky Sumarki Wardhana, Manggala Pasca Widati Fatmaningrum Willy Sandhika WITA SARASWATI, WITA Yuliana, Baiq Ade Herna Yuski Amin