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CHARACTERISTICS AND RISK FACTORS OF PATIENTS WITH NASOPHARYNGEAL CARCINOMA IN WEST NUSA TENGGARA HOSPITAL Mochammad Alfian Sulaksana; Hamsu Kadriyan
INTERNATIONAL JOURNAL OF NASOPHARYNGEAL CARCINOMA Vol. 1 No. 03 (2019): International Journal of Nasopharyngeal Carcinoma
Publisher : TALENTA PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijnpc.v1i03.2058

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Introduction Nasopharyngeal carcinoma (NPC) is the most common cancer in the head and neck. NPC is a malignancy of squamous cell on nasopharyngeal epithelial with the most common predilection site in rosenmuller fossa. Theetiology of this disease are multifactorial. A low oral hygiene on naso-oro-hypopharyngeal/laryngeal wall, Epstein Barr Virus (EBV) infection, smoking, alcohol consumption, genetic/hereditary factors, exposure to radiation, nutritional, deficiencies or decreased imune system are recognized as a risk factors. The study aim is to find out a characteristic of patients with nasopharyngeal carcinoma and their risk factors in the west Nusa Tenggara Hospital in September-October 2018. Methods The study design was descriptive–cross sectional. The research subjects were NPC patients who came to the West Nusa Tenggara Hospital ENT-HNS Clinic, in the period September-October 2018. Results There were 37 patients enroled to this study. According to this study, the most patients found in age group 46 to 55 years (35.1%), predominantly men (67.6%) with the men and women ratio 2.5: 1. Based on patients origin, they come from all districts in west Nusa Tenggara province, with the most districts found in West Lombok (29.7%). The most risk factors were food factors (food preservative 19.9%, food flavoring 19.9%, salted fish 15.6% carcinogenic (grilled food) 6.5%), and environmental factors (cigarettes 11.3%, smoke 4.8 % and 4.8% dust). Conculsion There were several risk factors found in this study, however, the most risk factor was food factors (61.9%) followed by environmental factors (20.9%).
THE RELATIONSHIP BETWEEN THE STAGE OF NASOPHARYNGEAL CARCINOMA WITH ANEMIA AND NUTRITIONAL STATUS IN WEST NUSA TENGGARA GENERAL HOSPITAL Ni Ketut Susilawati; Hamsu Kadriyan; Wayan Putu Sutirtayasa
INTERNATIONAL JOURNAL OF NASOPHARYNGEAL CARCINOMA Vol. 2 No. 01 (2020): International Journal of Nasopharyngeal Carcinoma
Publisher : TALENTA PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijnpc.v2i01.3579

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Introduction: Nasopharyngeal carcinoma is the most common malignant tumor in the ENT-HNS were the highest of all malignant tumors of the head and neck. Malnutrition and cachexia is a common problem in cancer patients and impact on quality of life and survival. Anemia is a major problem in patients with nasopharyngeal cancer receiving chemotherapy or radiotherapy. Objective: Determine the relationship of nasopharyngeal carcinoma stage with anemia and nutritional status. Material and methods: This study used cross sectional analytic method. Data were obtained from medical records of patients with nasopharyngeal carcinoma who were treated in province hospital West Nusa Tenggara period January 2018 to December 2018. Data collected include the identity, diagnosis, hemoglobin value, weight and height. Having analyzed the data collected are looking for is there a relationship between stage nasopharyngeal carcinoma with anemia and nutritional status. Results: In this study, Shapiro-Wilk normality test. Anova is then performed to analyze the relationship stage nasopharyngeal carcinoma with anemia status obtained 95% CI, p value 0.847, there is no difference between stage nasopharyngeal carcinoma with anemia. Kruskal Wallis test to analyze the relationship with BMI (body mass index) with stage nasopharyngeal carcinoma obtained 95% CI, p value 0.565. There is no difference in BMI with stage nasopharyngeal carcinoma. Conclusion: There is a tendency to lower Hb in patients with nasopharyngeal cancer further stage although there is no significant difference between each stage. The same thing was found in BMI, BMI decreased tendency in patients with advanced nasopharyngeal cancer although there was no statistically significant difference.
Bone Metastases in Nasopharyngeal Carcinoma Ni Ketut Susilawati; Hamsu Kadriyan
INTERNATIONAL JOURNAL OF NASOPHARYNGEAL CARCINOMA Vol. 2 No. 03 (2020): International Journal of Nasopharyngeal Carcinoma
Publisher : TALENTA PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijnpc.v2i03.4438

Abstract

Introduction: The incidence of bone metastases is as much as 20% of all distant metastases in nasopharyngeal carcinoma (NPC). However, the publication regarding bone metastasis is limited. Case Report: Reported a 58-year-old male patient with a mass on the right upper jugular neck lymph node. According to history taking, physical examination, radiology, and histopathology work up, concluded that the patients were established as nasopharyngeal cancer with the thoraco-lumbal bone metastasis. The physician was starting the chemotherapy; however, due to the advanced stage, this patient was death after the second chemotherapy. Conclusion: In this article presented a nasopharyngeal carcinoma case with bone metastases that have been diagnosed with stage IV B nasopharyngeal carcinoma. This article also described the pathophysiology, diagnosis, and treatment of bone metastases in nasopharyngeal carcinoma.
Pelatihan Teknik Cuci Tangan (WHO, 2009) Pada Guru Dan Siswa SDIT Anak Soleh Mataram E. Hagni Wardoyo; Didit Yudhanto; Hamsu Kadriyan; Triana Dyah Cahyawati; Yoga Pamungkas Susani; Titi Pambudi Karuniawaty
Prosiding Konferensi Nasional Pengabdian Kepada Masyarakat dan Corporate Social Responsibility (PKM-CSR) Vol 1 (2018): Prosiding PKM-CSR Konferensi Nasional Pengabdian kepada Masyarakat dan Corporate Socia
Publisher : Asosiasi Sinergi Pengabdi dan Pemberdaya Indonesia (ASPPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (238.531 KB)

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Prevention of infectious diseases in hospital, for example applied correct hand hygiene technique has been required applied its in the community. Due to a rise incidence of infectious diseases in the community, the capacity to perform hand hygiene technique has become important. Elementary student and their teacher are an effective agent of change in the community can help to socialize this important matter according to WHO (2009) hand hygiene technique. Community Devotion and Empowerment Team, Faculty of Medicine Mataram University had been undergone Hand hygiene technique to 110 students and 6 teachers of SDIT Anak Soleh Mataram. Learning strategies to elementary school age takes interesting technique using videos and demonstration using Lumigerm® lotion, a washable germ mimic that invisible under daylight and can only be seen under UV light. The results showed an increase in understanding technique from 34.5 to 82.6 (pretest and post test, respectively) and 88% participants were able to diminish lumigerm lotion properly after hand hygiene demonstration under UV light checked.
Teledermatology for managing COVID-19 patients with cutaneous manifestation: case series study in a rural primary hospital Dedianto Hidajat; Hamsu Kadriyan; Slamet Tjahjono
Intisari Sains Medis Vol. 13 No. 1 (2022): (Available Online : 1 April 2022)
Publisher : DiscoverSys Inc.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15562/ism.v13i1.1224

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Background: To provide information and experience about using WhatsApp as a tool in teledermatology to facilitate the identification, treatment, and follow-up of skin problems in COVID-19 patients hospitalized at one of a rural primary hospital located in Indonesia.Methods: All COVID-19 patients with the dermatology manifestation were included in this study. All symptoms and signs of cutaneous manifestation and teledermatology consultation aspect were recorded.Results: There were 7 cases confirmed with skin manifestation (0.9%) from 783 hospitalized patients from March 2020 to June 2021. There were 5 males and 2 females. The age range was 50 - 66 years old. Pruritus is the main complaint, followed by pain and swelling. The cutaneous lesions were mainly maculopapular, followed by papulovesicular and edematous eruptions. The onset of the lesions appeared between the 2nd and 12th day during hospitalization. Both patients and physicians feel comfortable using this platform in consultation.Conclusion: There are advantages and disadvantages to utilizing this concept in the medicolegal aspects, including non-uniform audio-visual quality and also ethical and privacy issues, especially in a rural area.
Pengenalan Gejala Nasopharyngeal Cancer pada Populasi Beresiko di Lombok Utara 2021 pada saat Pandemi Covid19 Hamsu Kadriyan; Didit Yudhanto; Triana Dyah Cahyawati; Novia Andansari Putri R; Niti Wedayani
Jurnal Pengabdian Magister Pendidikan IPA Vol 5 No 3 (2022): Juli - September
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (207.608 KB) | DOI: 10.29303/jpmpi.v5i3.2134

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Kanker adalah salah satu penyebab dari kematian, keganasan kepala dan leher yang paling sering terjadi adalah karsinoma nasofaring. Di dunia terdapat 86,500 kasus karsinoma nasofaring dan tercatat menyebabkan 50.000 kematian. Salah satu penyebab Karsinoma nasofaring adalah terinfeksi virus Epstein- Barr, dan di China, karsinoma nasofaring merupakan penyebab kecacatan dan kematian terbanyak untuk 2 karsinoma kepala dan leher. Metode Pelaksanaan kegiatan pengabdian ini adalah dengan: memberikan pengarahan oleh paramedis di Desa Binaan Kabupaten Lombok Utara bahwa akan dilakukan pengabdian berupa edukasi dan disepakati kapan dapat dilakukan. Masyarakat Desa Binaan Kabupaten Lombok Utara dikumpulkan pada waktu yang bersamaan dengan para medis dibawah pengawasan dokter spesialis Telinga Hidung dan Tenggorokkan Kepala Leher. Pengabdian Masyarakat mengenai tanda dan gejala Nasopharyngeal cancer pada kelompok beresiko amatlah penting, agar masyarakat dapat mengetahui tanda dan gejala serta faktor – faktor penyebab Nasopharyngeal cancer. Perlu dilakukan pengabdian secara berkala dan juga pemeriksaan Telinga Hidung dan Tenggorokan pada masyarakat yang memiliki faktor risiko seperti masyarakat di Desa Binaan Gumantar yang permukimannya dekat dengan tambak dan sering mengkonsumsi ikan asin.
FAKTOR RESIKO DAN MANAJEMEN PTERIGIUM PADA PENDUDUK DAERAH PESISIR Naurah Nazhifah; Hamsu Kadriyan
JURNAL INOVASI PENDIDIKAN DAN SAINS Vol 3 No 3 (2022): Desember
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Nahdlatul Wathan Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51673/jips.v3i3.1184

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Pterigium berasal dari bahasa Yunani, yaitu pteron, yang berarti sayap. Pterigium adalah tumbuhnya jaringan fibrovaskular yang abnormal dengan bentuk segitiga dari konjungtiva yang meluas ke kornea. Ini merupakan gangguan proliferatif dari permukaan okular, yang disebabkan oleh remodeling jaringan ikat dan angiogenesis yang menyebabkan proliferasi fibrovaskular. Jurnal ini bertujuan untuk memberikan informasi tentang faktor resiko dan manajemen pterigium pada penduduk daerah pesisir. Pekerjaan sebagai petani/nelayan/ buruh mempunyai prevalensi pterigium tertinggi yaitu 15.8%. Faktor resiko pterigium yang paling berpengaruh terhadap masyarakat pesisir adalah pekerjaannya sebagai seorang nelayan, dan juga berada pada area ekuator yang merupakan area dengan paparan sinar matahari yang tinggi, hal ini dapat memicu terjadinya pterigium. Pekerjaan sebagai seorang nelayan yang dilakukan selama bertahun-tahun dan berjam-jam, yang rata-rata berkisar 7 jam keatas untuk paparan terhadap sinar matahari langsung juga dapat memicu terjadinya pterigium. Manajemen pterigium yang dapat dilakukan yaitu pemberian obat tetes mata untuk mengurangi keluhan, kemudian melakukan tindakan operasi atau pembedahan dengan menggunakan teknik eksisi yaitu baresclera, Conjunctival autograft technique, dan Amniotic membrane grafting. Tingkat kekambuhan yang tinggi terkait komplikasi pascaoperasi sering terjadi dengan demikian manajemen medis tambahan telah dimasukkan dalam perawatan bedah pterigium yaitu mitomycin C, anti-VEGF, 5-fluorouracil (5-FU) dan loteprednol etabonate.
OXTR Gene mRNA Expression is Correlated to Prosocial Behavior of Children in the Golden Generation Program of Nusa Tenggara Barat Wilya Isnaeni; Suryani As'ad; Mochammad Hatta; Saidah Syamsuddin; Fahrin Ramadan Andiwijaya; Hamsu Kadriyan
The Indonesian Biomedical Journal Vol 14, No 4 (2022)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v14i4.2021

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BACKGROUND: Cases of undernutrition, such as stunting and wasting, in Nusa Tenggara Barat (NTB), Indonesia, was found to be relatively high. Therefore, local government launched a golden generation program called GEN NTB to improve the quality of human resources by achieving a healthy, intelligent, devout, and productive generation in 2045. One of the genes known to be related with prosocial behavior is the oxytocin transferase (OXTR) gene. This study was conducted to determine the association between OXTR gene mRNA expression and prosocial behavior of the GEN NTB children.METHODS: This was an analytical observational case-control study involving 25 children as GEN NTB samples and 26 children as controls. Blood samples were tested for OXTR protein level with enzyme-linked immunosorbent assay (ELISA), and OXTR mRNA expression with real time polymerase chain reaction (RT-PCR). Prosocial behavior was characterized and determined by using a rating method, which valued from 1 to 4 for poor to very good behavior.RESULTS: The average OXTR protein levels of the GEN NTB group was 88.28 ng/mL, which were higher than the average OXTR protein levels of control group (2.41 ng/mL). According to fold change analysis, the OXTR mRNA expression in GEN NTB group was also higher than the control group (10.91 vs. 6.40). Interestingly, observations on the prosocial behavior of the GEN NTB group showed significantly higher rate values compared to the control group (17.3 vs. 8.0, p=0.034). Hence, these findings showed that the OXTR protein level and OXTR mRNA expression was correlated with the better prosocial behavior.CONCLUSION: Higher rating of prosocial behavior of the GEN NTB children is related to the higher OXTR mRNA expression levels. This might be attributed to the interventions of GEN NTB program that may elevate children's quality of life since early childhood.KEYWORDS: GEN NTB, OXTR protein, mRNA expression, prosocial behavior, children
PENGENALAN DAN EDUKASI MENJAGA KEBERSIHAN SALURAN PERNAFASAN DENGAN MENCUCI HIDUNG PADA PANDEMI COVID19 DI POLI THT-KL RS RS UNRAM DAN RSUDP NUSA TENGGARA BARAT 2021 A. A. Niti Wedayani; Hamsu Kadriyan; Catarina Budyono
Jurnal Pepadu Vol 3 No 3 (2022): Jurnal PEPADU
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (236.393 KB)

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Latar Belakang: Kebersihan saluran pernafasan sangat penting terutama dalam situasi Pandemi COVID-19 selain untuk meningkatkan imunitas juga untuk menjaga hygenitas. Tujuan: meningkatan pengetahuan masyarakat untuk membersihkan saluran pernafasan atas Metode: penyuluhan kepada masyarakat awam mengenai cara mencuci hidung untuk meningkatkan imunitas di masa Pandemi COVID-19. Hasil: Selama 2 tahun pandemic 100% peserta mengalami infeksi pernafasan. Dari 20 peserta pengabdian, 20 peserta tidak mengetahui cara dan manfaat dari mencuci hidung, Setelah dilakukan edukasi peserta pengabdian menjadi mengetahui cara dan manfaat dari mencuci hidung. Dari 10 soal quisioner 16 peserta menjawab dengan benar sesuai edukasi, 4 peserta masih keliru dalam menjawab langkah mencuci hidung. Kesimpulan: pengetahuan tentang cara mencuci hidung sangat penting dalam meningkatkan imunitas, terutama di masa pandemi. Kurangnya pengetahuan masyarakat menjadi masalah dalam usaha tenaga kesehatan, menjaga kesehatan masyarakat, sehingga perlu diberikan edukasi dan pengertian tentang pentingnya cara mencuci hidung untuk mengurangi kejadian infeksi pernafasan.
Well-organized Granuloma Lymphadenitis Tuberculosis Expressed Lower Macrophage Migration Inhibitory Factor (MIF) Score Compared to the Poorly-organized Granuloma Hamsu Kadriyan; Fathul Djannah; Philip Habib; Triana Diah Cahyawati; Nurhidayati Siddik
The Indonesian Biomedical Journal Vol 15, No 1 (2023)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v15i1.2070

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BACKGROUND: The case of extra-pulmonary tuberculosis (EPTB) is common and the most type of extra-pulmonary tuberculosis found is lymphadenitis TB (LnTB). Macrophage migration inhibitory factor (MIF) is correlated with TB, and low level of MIF was correlated to Mycobacterium TB bacteremia. Deficiency of MIF macrophage is known to be correlated to the increased of a lung pathology; however, its role on pathogenesis LnTB remains unclear. Hence, this study was conducted to analyze the correlation of MIF in several type of granuloma organization in LnTB.METHODS: Block paraffin of the lymphoid tissue infected with M. Tuberculosis were analyzed with immunohistochemistry (IHC) to assess the MIF expression, by counting the immunoreactivity score (IRS) according to the intensity of stained cells and the level of staining. The histopathology type of LnTB was divided into well-organized granuloma (WOG) and poorly-organized granuloma (POG) based on the granuloma characteristics.RESULTS: Among 100 tissues samples that fulfilled the study criteria, WOG was found in 51% cases. MIF was expressed mild positive in 21% samples, on the other hand, 79% was not expressed. There was a significant difference of MIF negative, as was found in 98% of WOG group while only 59% was found in POG group (p<0.001).CONCLUSION: There is a significant correlation between MIF expression with the type of granuloma organization in LnTB. The expression of MIF in WOG group is mostly negative, as well as a half of the POG group. This results may suggests that MIF plays a role in the pathogenesis of granuloma formation in LnTB.KEYWORDS: MIF, lymphadenitis TB, WOG, POG, immunohistochemistry
Co-Authors A. A. Niti Wedayani Abdul Qadar Punagi Abiyu Didar Haq Achmad Chusnu Romdhoni Agus Supinganto Agusalim Bukhari Anak Agung Ayu Niti Wedayani Anak Agung Ayu Niti Wedayani Andhito Rafid Chusaeri Andi Alfian Zainuddin Arfi Syamsun As Shiddiq, Muhammad Hilmy Astini, Baik Nilawati Baik Nilawati Astini Baiq Endang Suprihartini Baiq Ghassani Kayla Baiq Nabila Saufika Zainuri Budu Budu Catarina Budyono chaeruddin, Muhammad bagus syaiful Cut Warnaini Dedianto Hidajat Dewa Agung Istri Sintha Prajnyaswari Dhea Natashia Dian Puspita Sari Didit Yudhanto Didit Yudhanto Didit Yudhanto E. Hagni Wardoyo Eka Arie Yuliani Eka Arie Yuliyani Eka Arie Yuliyani Eka Arie Yuliyani Eka Sunarwidhi Prasedya Emmy Amalia Eva Triani Fahrin Ramadan Andiwijaya Faisal Libryan Farahiya, Maya Fathul Djannah Fathul Djannah Febrian, Haldy Dwi Fitriatulnisa G. Gunawan Gaffar, Masyita Gede Rama Hardy Nugraha Gunawan Gunawan Gusti Ayu Trisna A Gusti Ayu Trisna Aryani Gusti Ayu Trisna Aryani Haldy Dwi Febrian Haq, Abiyyu Didar I Gede Pasek Sutawijaya I Gede Wiranugraha I Gusti Kamasan Arijana I Made Jawi I Wayan Gede Artawan Eka Putra I Wayan Putu Sutirta Yasa Ida Ayu Eka Widiastuti Indana Eva Ajmala Kholifaturrohmy, Muhammad Rizqi Lalu Hizrian Zikri Hamdi Lalu Muhammad Abiyu Ghafar Lina Nurbaiti Luh Ade Dita Rahayu M. Syarif Hidayatullah Made Ratna Dewi Marisa Syavitri Dilaga Mochammad Alfian Sulaksana Mochammad Alfian Sulaksana Mochammad Alfian Sulaksana Mochammad Hatta Muhammad Alfian Sulaksana Muhammad Amsyar Akil Muthia Cenderadewi Naurah Nazhifah Ni Ketut Metri Ni Ketut Susilawati Ni Ketut Susilawati Ni Ketut Susilawati Ni Ketut Susilawati Ni Made Yeni Suranti Ni Made Yeni Suranti Ni Made Yeni Suranti Nini Asri Rahmayunita Niti Wedayani Nova Audrey Luetta Pieter Novia Andansari Putri R Nuraini Staryo Nurhidayati Nurhidayati Siddik Philip Habib Pratama, Aditya Agung Primaditha, Dara Qothrunnada Qothrunnada Rahayu, Luh ade dita Raufina Riandhani Mulyoto Rina Lestari Rina Masadah Rista Rahayu Rarasati Ru’yi, Hartini Ahadiyatur Saidah Syamsuddin Slamet Tjahjono Sri Maliawan Suharmanto Suharmanto Sulaksana, Mochammad Alfian Sumarmi Sumarmi Suryani As&#039;ad Titi Pambudi Karuniawaty Triana Diah Cahyawati Triana Dyah Cahyawati Triana Dyah Cahyawati Wahyu Sulistya Affarah Wayan Suardana Wilya Isnaeni Yoga Pamungkas Susani Yuliani, Eka arie Yuliyani, Eka Arie