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All Journal The Indonesian Biomedical Journal Sari Pediatri Paediatrica Indonesiana Molecular and Cellular Biomedical Sciences (MCBS) Smart Medical Journal Jurnal Gizi Klinik Indonesia Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Journal of Maternal and Child Health Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Placentum: Jurnal Ilmiah Kesehatan dan Aplikasinya Jurnal Kesehatan Masyarakat
Annang Giri Moelyo
Department Of Child Health, Faculty Of Medicine, Sebelas Maret University, Surakarta
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Knee height and knee height/height ratio of healthy schoolchildren Annang Giri Moelyo; Andre Christiawan Susanto; Bella Monika Rajagukguk; Jonathan Billy Christian Tjiayadi
Paediatrica Indonesiana Vol 60 No 5 (2020): September 2020
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi60.5.2020.233-8

Abstract

Background Knee height (KH) is rarely used to estimate stature in children, although its measurement might have benefit because not influenced by some musculoskeletal disorder in spinal region. Knee height and knee height/height ratio are typical in children due to different in pubertal timing of each child. Objective To derive a formula to estimate body height using knee height and to analyze the patterns of knee height and knee height/height ratio of healthy schoolchildren. Methods This cross-sectional study involved healthy children in one elementary school and one junior high school in Surakarta, Central Java. Demographic data were collected (sex, age, and ethnicity). All anthropometric measurements (height, weight, sitting height, and knee height) were taken three times, and their means were calculated. Linear regression analysis was used to compare height from knee height and sitting height. Non-parametric analysis through locally weighted scatterplot smoothing (LOWESS) was used to analyze the growth patterns of knee height, knee height/height ratio, and sitting height/height ratio. Results There were 633 children (328 boys and 305 girls) in this study. The formulas for the estimation of height were as follows: for boys, 2.40 × KH (cm) + 1.36 × age (years) + 20.31; and for girls, 2.48 × KH (cm) + 1.15 × age (years) + 19.58 (adjusted R2=0.97). Knee height increased earlier than sitting height in both boys and girls during childhood to adolescent period. Boys had a longer period of knee height increment than girls. Conclusion Knee height may be a useful alternative to estimate height in children. Knee height increases faster than height and sitting height in both boys and girls.
BURNOUT AMONG PEDIATRIC TRAINEES IN INDONESIA: A NATIONAL SURVEY Annang Giri Moelyo; Bambang Tridjaja; Rina Triasih
Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Vol 10, No 3 (2021): November
Publisher : Asosiasi Institusi Pendidikan Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpki.63683

Abstract

Background: The intense workload and complex learning environment in pediatric specialist training program may lead to trainees’ burnout. The study aimed to assess burnout and the associated factors among pediatric trainees in Indonesia.Methods: We conducted a multicentre study involving all (15) pediatric training institutions in Indonesia from June to August 2019. A General Oldenburg Burnout Inventory (OLBI) was translated to Indonesian language. The OLBI comprised of 16 questions which assessed exhaustion (8 questions) and disengagement (8 questions). The online questionnaire was self-completed by pediatric trainees in the study sites. Ordinal regressions were performed to assess risk factors (age, marital, sex, resident stage of training, and university) for exhaustion and disengagement.Results: A total of 841 trainees from 15 pediatric training institutions in Indonesia completed the survey (response rate 71.2%). The majority (72.1%) of the trainees was female with mean age of 31.2 ± 2.9 years. The Cronbach’s-alpha was 0.74. The mean exhaustion and disengagement scores were 2.58±0.23 and 2.51±0.23, respectively. The proportion of vigor, mild, moderate and severe exhaustion were 48.3%; 42.0%; 9.0%; and 0.7%, respectively. The proportion of dedicated, mild, moderate and severe disengagement were 36.9%; 46.5%; 14.5%; and 2.1%, respectively. The stage of training (junior-intermediate stage), after adjusted to age, sex and institution was significantly increase the risk for exhaustion [odd ratio 1.47 (95%CI; 1.22-1.76)]. Disengagement level was significantly different among pediatric training institutions (located in Java and outer Java) [odd ratio 0.68 (95%CI; 0.529-0.885)].Conclusion: Burnout was common among pediatric trainees in Indonesia.
Using the National Indonesian Growth Chart to assess short stature and obesity in urban schoolchildren in Surakarta, Indonesia: comparisons to the WHO 2007 and CDC 2000 Growth Charts Annang Giri Moelyo; Dewinda Candrarukmi; Ulfa Puspita Rachma
Paediatrica Indonesiana Vol 62 No 3 (2022): May 2022
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi62.3.2022.180-5

Abstract

Background The National Indonesian Growth Chart (NIGC) is a new growth chart based on Indonesian population data. To date, the CDC 2000 or WHO 2007 charts have been widely used in Indonesia to assess the growth of 5-to-18-year-old children. Use of these reference charts may lead to inaccurate conclusions about children’s nutritional status, particularly when diagnosing short stature or obesity. Objective To compare assessments of short stature and obesity in Indonesian urban schoolchildren and adolescents based on CDC, WHO, and NIGC reference charts. Methods Pooled anthropometric data [height, weight, and body mass index (BMI)] were collected cross-sectionally from healthy schoolchildren aged 6 to 18 years in Surakarta in 2013, 2016, 2018, and 2019. We created scatterplots for height, weight, and BMI and analyzed differences in height-for-age (HAZ) and BMI (BAZ) z-scores according to the CDC, WHO, and NIGC growth charts, then calculated differences in proportions of children identified as having short stature or obesity. Results We included 2,582 subjects; 63% were girls. Subjects’ mean age was 13.1 (SD 3.4) years. Mean differences in HAZ between the NIGC vs. CDC chart and NIGC vs. WHO chart were 1.44 (SD 0.01) and 1.39 (SD 0.00), respectively. Mean differences in BAZ between the NIGC vs. CDC chart and NIGC vs. WHO chart were 0.18 (SD 0.01) and 0.06 (SD 0.01), respectively. The prevalence of short stature was 9.91%, 11.62%, and 0.39% according to the WHO, CDC, and NIGC charts, respectively. The prevalence of obesity was 10.15%, 5.07%, and 11.77% according to the WHO, CDC, and NIGC charts, respectively. The prevalence of obesity according to the WHO, CDC, and NIGC was 7.44%, 2.95%, and 10.08%, respectively in girls and 14.76%, 8.69%, and 14.66%, respectively in boys. Conclusion The use of the NIGC resulted in a lower prevalence of short stature compared to the CDC or WHO charts. Compared to the WHO charts, the NIGC gave a similar prevalence of obesity overall and in boys, but a higher prevalence of obesity in girls. Compared to the CDC charts, the NIGC gave a higher prevalence of obesity both in boys and girls.
ADAPTING THE OLDENBURG BURNOUT INVENTORY INTO BAHASA INDONESIA FOR MEASURING BURNOUT IN MEDICAL RESIDENTS Annang Giri Moelyo; Muchtar Hanafi
Jurnal Pendidikan Kedokteran Indonesia: The Indonesian Journal of Medical Education Vol 11, No 2 (2022): JUNI
Publisher : Asosiasi Institusi Pendidikan Kedokteran Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jpki.56213

Abstract

 Background: Burnout is common among medical residents, and a non-commercial tool for assessing burnout for medical residents is needed. This study aimed to adapt the Oldenburg Burnout Inventory (OLBI) in Bahasa Indonesia for medical residents and to analyze its validity and reliability.Case Discussion: The English version of OLBI was forward and backward translated to and from Bahasa Indonesia by English-language translation experts, and was appropriately modified by the authors. The respondents of the questionnaire were taken from pediatric residents in the first trial (48 subjects), and from internal medicine, pediatric, dermatology, surgery, and neurology residents in the second trial (109 subjects). The item-test correlation to measured construct validity was good for both trials. A confirmatory factor analysis was then undertaken to evaluate the goodness of fit (GOF), the root mean squared error of approximation (RMSEA), comparative fit index (CFI), Tucker-Lewis index (TLI), standardized root mean squared residual (SRMR), and coefficient of determination (CD) in the second trial. The results of the one-factor model and multidimensional GOF of the 16 items were unsatisfactory (χ2<0.05 and RMSEA>0.08). The GOF of the two-factor analysis of burnout with 8 items (3 exhaustion items and 5 disengagement items) created the following results: χ2=0.378; RMSEA=0.025; CFI=0.995; TLI=0.993; SRMR=0.036; and CD=0.898. The Cronbach’s alphas, for internal consistency reliability, in the first trial, second trial, and final model were 0.73, 0.87, 0.83, and 0.79, respectively.Conclusion: An 8-items modified Bahasa Indonesia translation of the OLBI for medical residents to measure burnout has good reliability and validity. 
D-dimer as a Potential Biomarker of Severity in Children Confirmed with COVID-19 Hanum Ferdian; Rustam Siregar; Annang Giri Moelyo
Molecular and Cellular Biomedical Sciences Vol 6, No 3 (2022)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21705/mcbs.v6i3.276

Abstract

Background: Coronavirus disease 2019 (COVID-19) in children spreads easily and has a relatively high incidence. Severe complications in children confirmed with COVID-19 are thought to be related to the multisystem inflammatory syndrome, which is associated with coagulation disorders. D-dimer is a fibrin degradation end product which is easy to examine, affordable, fast and reliable. This study investigated the potency of D-dimer levels as a biomarker and assessed optimal cut-off value of D-dimer on severity of COVID-19 in children. Materials and methods: An analytical observational study with a cross-sectional design was conducted in children aged 1-18 years confirmed to have mild, moderate or severe COVID-19 who were treated in the isolation room of Dr. Moewardi Hospital, Surakarta, Indonesia from September 2021 to February 2022. Statistical analysis was conducted using Mann- Whitney test and p<0.05 was considered as statistically significant. The cut-off value of D-dimer was determined with the receiver operating characteristic (ROC) curve. Results: There were 39 children with COVID-19. They were in mild (n=14; 35.9%), moderate (n=19; 48.7%) and severe (n= 6; 15.4%) stages. There were significant differences in D-dimer levels between mild and moderate stages (p=0.001), and mild and severe stages (p=0.001). No significant difference in D-dimer levels between moderate and severe stages (p=0.162). The cut-off value of D-dimer was 485 μg/mL with 92% sensitivity and 71.4% specificity. Conclusion: D-dimer can be used as a potential biomarker of severity in children with COVID-19.Keywords: D-dimer, COVID-19, severity, children
Analisis Deskriptif Temuan Klinis, Laboratorium, dan Radiologis Pasien Anak dalam Pemantauan Covid-19 di Rumah Sakit Dr. Moewardi Rizki Sulistyanto; Ismiranti Andarini Ismiranti Andarini; Annang Giri Moelyo Annang Giri Moelyo
Sari Pediatri Vol 24, No 5 (2023)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp24.5.2023.314-19

Abstract

Latar belakang. Indonesia melaporkan kasus konfirmasi Covid-19 pertama kali pada tanggal 2 Maret 2020, dan beberapa daerah telah dinyatakan telah terjadi transmisi lokal. Data mengenai gambaran penyakit Covid-19 pada anak sangat terbatas. Tujuan. Mengetahui gambaran klinis, laboratorium dan radiologis PDP (Pasien Dalam Pemantuan) anak di Rumah Sakit dr. Moewardi Surakarta.Metode. Penelitian ini merupakan penelitian deskriptif analitik, dilakukan di Rumah Sakit dr. Moewardi Surakarta. Kriteria inklusi adalah pasien anak yang dirawat di ruang Isolasi Rumah Sakit dr. Moewardi Surakarta, antara bulan April-Oktober 2020.Kriteria eksklusi yaitu pasien meninggal dunia sebelum dilakukan swab tenggorokan. Hasil. Penelitian ini menggunakan data rekam medis, didapatkan 194 subyek penelitian, 36 pasien terkonfirmasi Covid-19. Usia rerata pasien terkonfirmasi covid adalah 4.61+5.93 tahun. Dari gejala klinis, temuan laboratorium, dan temuan radiologi tidak menunjukkan adanya perbedaan yang signifikan (p>0,05). Pasien terkonfirmasi Covid-19 didapatkan faktor komorbid (p=0,001), diantaranya kardiovaskuler (6%) dan CNS (14%).Kesimpulan. Tidak ada gambaran khas pada pasien anak terkonfirmasi Covid-19.
Pediatric residents’ burnout in Indonesia: a national survey during the pandemic Annang Giri Moelyo; Ardi Findyartini; Bambang Tridjaja; Aryono Hendarto
Paediatrica Indonesiana Vol 63 No 1 (2023): January 2023
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi63.1.2023.22-8

Abstract

Background The uncertain and somewhat chaotic clinical learning environment during the COVID-19 pandemic may potentially trigger burnout in pediatric residents. Objective To investigate the prevalence of burnout in pediatric residents in Indonesia during the COVID-19 pandemic and to identify potential risk factors associated with burnout. Methods This analytic observational study was conducted between April and June 2020. A questionnaire-based survey using an Indonesian translation of the Maslach Burnout Inventory-Human Services Survey was conducted online across 15 pediatric training institutions treating COVID-19 patients in Indonesia. Results were interpreted in accordance with the inventory guidelines. The chi-square test was used to analyze for possible associations between each subscale and gender, marital status, training stage, as well as institution of origin. One-way ANOVA of each subscale was performed on pediatric training institutions located in different regions. Results Of 983 respondents (82% average response rate), the prevalences of high emotional exhaustion and high depersonalization were 28.0% and 15.8%, respectively, while more than half of respondents (50.2%) had a low sense of personal accomplishment. Most respondents felt more exhausted than depersonalized. The location of pediatric training institution (Java or outside Java) was the only significant factor associated with burnout (P=0.003). Conclusion In the early stages of the pandemic, more than half of pediatric residents in Indonesia had a low sense of personal accomplishment. The only significant factor associated with burnout among was the location of training institution (Java or outside Java), suggesting a potential role of differences in hospital situation and clinical learning environment during the pandemic between Java and outside Java.
Cortisol levels associated with mortality in children with critical illness: a systematic review Tolibin, Restu Triwulandani; Widiretnani, Septin; Moelyo, Annang Giri
Paediatrica Indonesiana Vol. 63 No. 6 (2023): November 2023
Publisher : Indonesian Pediatric Society

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/pi63.6.2023.472-82

Abstract

Background Critically ill patients, including those with sepsis, have increased cortisol levels due to activation of the hypothalamic-pituitary-adrenal (HPA) axis or critical illness-related corticosteroid insufficiency (CIRCI). Objective To evaluate for a possible association between cortisol levels and mortality from sepsis in pediatric patients by systematic review of the literature. Methods A systematic review was conducted on studies involving critically ill children, including those with sepsis. We included studies published between 2011-2020 analyzing data on cortisol levels (total serum cortisol, serum-free cortisol, salivary cortisol, real-time free cortisol, basal serum cortisol and post-adrenocorticotropin hormone (ACTH) stimulation test, or basal salivary cortisol and post-ACTH stimulation test), the predictive score for mortality (Pediatric Logistic Organ Dysfunction/PELOD), Pediatric Risk of Mortality (PRISM), Pediatric Index of Mortality (PIM), Vasotropic Inotropic Score (VIS), or Pediatric Critical Illness Score (PCIS)], mortality (non-survivor percentage), and CIRCI percentage as an outcome in patients with critical illness, sepsis, and septic shock. Results Twenty-one observational studies were included in our systematic review, with a total of 2,212 subjects, 916 of whom had sepsis. Nineteen studies indicated a positive association between elevated cortisol levels and mortality in critically ill children, but 2 studies stated that there was no association with the CIRCI percentage of 32.3 and 84.3% respectively. The mortality percentage of critically ill patients with elevated cortisol levels and sepsis were 25.81 (2.7-60)% and 35.31 (6-60)%, respectively. The percentages of CIRCI in critically ill and sepsis patients were 21.91 (0-84.3)% and 21.35 (0-84.3)%, respectively. Conclusion Cortisol levels may increase or decrease in critically ill children. Elevated cortisol levels are associated with mortality in septic children. The effect of CIRCI on mortality in critically ill children cannot be concluded.
Vitamin D Deficiency is Associated with Hypocalcemia in Preterm Infants Nabiel, Nabiel; Nugroho, Hari Wahyu; Moelyo, Annang Giri
Molecular and Cellular Biomedical Sciences Vol 8, No 2 (2024)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21705/mcbs.v8i2.473

Abstract

Background: Vitamin D deficiency results in various problems, like rickets, osteomalacia, heart problems, cancer, diabetes, and autoimmune diseases. Hypocalcemia is a common disorder among preterm infants, indicating vitamin D deficiency. This study was conducted to analyze the association of vitamin D deficiency with hypocalcemia in preterm infants.Materials and methods: A cross-sectional study was performed in preterm infants born in our hospital from December 2022 to May 2023. Venous blood was collected within the first 24 hours to assess vitamin D and calcium levels. Chi-square test and logistic regression analysis were used to assess the association of gestational age, sex, birth weight, and vitamin D with the incidence of hypocalcemia. The significance was determined with p<0.05.Results: There were 40 preterm newborns, comprising 37.5% moderately preterm, 20% very preterm, and 42.5% extremely preterm. Most subjects were female (52.5%). Low birth weight, very low birth weight, and extremely low birth weight occurred in 55%, 27.5%, and 17.5%, respectively. Vitamin D insufficiency and deficiency were observed in 20% and 80% subjects, respectively. Most subjects had hypocalcemia (62.5%). Chi-square test obtained a significant association of vitamin D deficiency with hypocalcemia (p=0.029).Conclusion: Vitamin D deficiency is significantly associated with the incidence of hypocalcemia in preterm infants.Keywords: Vitamin D, hypocalcemia, preterm neonates
Hubungan Durasi Tidur dengan Memori Jangka Pendek pada Siswa Sekolah Dasar Putra, Farras Handyra; Umma, Husnia Auliyatul; Moelyo, Annang Giri
Sari Pediatri Vol 26, No 3 (2024)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp26.3.2024.152-7

Abstract

Latar belakang. Fungsi tidur secara tepat hingga kini masih belum jelas, tetapi dipercaya bahwa kekurangan durasi tidur dapat menurunkan kinerja kognitif memori jangka pendek. Namun, hasil beberapa penelitian yang sudah dilaksanakan tidak sejalan dengan teori tersebut. Penelitian ini bertujuan untuk mengetahui apakah terdapat hubungan antara durasi tidur dan memori jangka pendek, dengan harapan mendapatkan hasil yang baru dan signifikan yang sejalan dengan teori yang sudah ada.Tujuan. Mengetahui hubungan antara durasi tidur dengan memori jangka pendek pada siswa SD Al-Islam 2 Jamsaren Surakarta.Metode. Penelitian ini menggunakan studi analitik cross-sectional dengan sampel siswa tingkat sekolah dasar kelas 4-6 SD Al-Islam 2 Jamsaren Surakarta. Instrumen yang digunakan adalah kuesioner SDSC untuk mengetahui durasi tidur dan tes FDST untuk menentukan kualitas memori jangka pendek anak. Teknik analisis yang digunakan adalah uji analisis chi-square dan uji multivariat regresi logistik. Jika pada analisis bivariat terdapat lebih dari 1 variabel bebas/perancu yang signifikan (p<0.25), maka dilanjutkan dengan analisis multivariat. Tes yang digunakan dalam penelitian ini adalah regresi logistik dengan signifikansi statistik p<0,05. Hasil. Hasil uji bivariat yang signifikan (p<0,05) didapatkan pada uji chi-square durasi tidur dengan memori jangka pendek.Kesimpulan. Terdapat hubungan antara durasi tidur dengan memori jangka pendek pada siswa tingkat sekolah dasar. 
Co-Authors . Widardo Andhika Trisna Putra Andre Christiawan Susanto Anggun Esti Wardani Anindita Wulandari Ardi Findyartini, Ardi Ari Natalia Probandari Aryono Hendarto Astuti, Anita Sefti Azzainabi, Nur Fatimah Nikmatullah Bambang Soebagyo Bambang Tridjaja AAP, Bambang Tridjaja Bella Monika Rajagukguk Cahyanto, Erindra Budi Cempaka Kesumaningtyas Dewinda Candrarukmi Dewinda Candrarukmi Dian Ibnu Wahid Elisabeth Nova Kurniasari Ema Nur Fitriana Eriana Melinawati Evi Rokhayati Evie Rokhayati Fadhilah Tia Nur Febry Dwi Indrawati Ferdian, Hanum Ganung Harsono Guntur Surya Alam Hanum Ferdian Hanum Ferdian Hanum Ferdian Hanum Ferdian Hari Wahyu Nugroho Hari Wahyu Nugroho Harsono Salimo Husnia Auliyatul Umma, Husnia Auliyatul Ilma Anisa Imasari Aryani Indah S. Widyahening Iskandar, Nurdin Aji Ismiranti Andarini Isna Noor Rakhmawati Isna Noor Rakhmawati Istar Yuliadi Istar Yuliadi Jonathan Billy Christian Tjiayadi Kartiko Kurnianto Kesit, Johan Wijaya Kumala, Soebhita Hema Laqif, Abdurahman Lucky Yogasatria Marcellia, Stefany Mardiyah, Putri Ma’rifatul Maulina, Rufidah Melita Widyastuti Muchtar Hanafi Muhammad Reza Muhammad Riza Muhammad Riza Nabiel, Nabiel Nabila Adib Sungkar Nanang Wiyono Nisa, Azzahra Fadhlila Aulia Novarianto, Justinus Kurniabudhi Nunki Andria Nurinasari, Hafi Nurul Hidayah Oktania Imas Pamungkas, Rafli Yuda Paramasari Dirgahayu Pratiwi, Tan Mike Prisola, Steiner Lukas Purnata, Lyviana Patrishia Putra, David Anggara Putra, Farras Handyra Rahayu, Cynthia Octaviani Rina Triasih Rizki Sulistyanto Rustam Siregar Samad Samad Sandra Lestari Sari Dwi Jayanti Sekarhandini, Pitra Senyum Indrakila Septin Widiretnani, Septin Soetrisno Soetrisno Suci Murti Karini Suci Murti Karini Sukamto, Ika Sumiyarsi Tiffany Satiadarma Tolibin, Restu Triwulandani Uki Retno Budihastuti Ulfa Puspita Rachma Ulfa Puspita Rachma Ulfa Puspita Rahma Wijayanti, Agung Sari Yusak Aditya Setyawan Zenia Purnama Murti