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<![CDATA[Acute Toxicity Test of Mulberry Leaf Extract (Morus rubra L) as a Basic Ingredient of Candida Albicans Antifungal on Rattus Norvecigus ]]>
<![CDATA[Nina Hidayatunnikmah]]>;
<![CDATA[Anik Latifah]]>
<![CDATA[ EMBRIO: Jurnal Kebidanan Vol 16 No 1 (2024): EMBRIO: Jurnal Kebidanan (MAY) ]]>
Publisher : <![CDATA[Program Studi S1 Kebidanan - Fakultas Ilmu Kesehatan Universitas PGRI Adi Buana Surabaya ]]>
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DOI: 10.36456/embrio.v16i1.9028
<![CDATA[Previous research on the effectiveness of mulberry leaves in the growth of candida albicans showed that C. albicans is inhibited in vitro. Mulberry leaf extract is used as a basic ingredient for treatment. In addition to being tested for effectiveness, testing is needed to ensure the level of acute toxicity in experimental animals in determining toxicity levels. The study aimed to test the acute toxicity of mulberry leaf extract on Rattus Norvecigus media in determining the level of toxicity before becoming the basic ingredient of VVC antifungal. The research method uses an experimental laboratory post-test-only control group design with a 9 Rattus Norvegicus media. The average dose is not lethal using LD50 values. Research analysis using ANOVA is One Way to determine the difference in the average weight change of experimental animals. The study's results did not show any deaths of experimental animals or toxic symptoms in administering mulberry leaf extract doses of 0 mg, 100mg, 1000 mg, 1600mg, 2900mg, 5000mg. LD50 value more than 8g/kg BW, included in the non-toxic category (5-15 g/kg BW). The ANOVA statistical test showed a P-value of 0.781 more than a P-value of 0.05, that is, there was no difference in the average change in body weight in the experimental animal group given different treatment doses in each group. The research concludes that mulberry leaf extract does not show a lethal dose of acute toxicity, so it is safe to use as a basic ingredient in treatment sourced from natural ingredients.]]>
<![CDATA[“PAK SARKIJO” PENCEGAHAN ANEMIA KEHAMILAN DENGAN SARI KACANG HIJAU ]]>
<![CDATA[Iswati, Retno Setyo]]>;
<![CDATA[Hidayatunnikmah, Nina]]>;
<![CDATA[Rihardini, Tetty]]>;
<![CDATA[Solichatin]]>
<![CDATA[ Jurnal Abadimas Adi Buana Vol 9 No 01 (2025): Jurnal Abadimas Adi Buana ]]>
Publisher : <![CDATA[LPPM Universitas PGRI Adi Buana Surabaya ]]>
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DOI: 10.36456/abadimas.v9.i01.a10470
<![CDATA[Anemia kehamilan merupakan kehamilan resiko tinggi yang memungkinkan sebagai penyebab kematian ibu hamil, seperti perdarahan, eklampsia, dan infeksi. Berdasarkan hasil pengkajian data di RW 02 Kecamatan Siwalankerto Kota Surabaya didapatkan 5 dari 13 ibu hamil yang memiliki status kehamilan dengan resiko tinggi sebesar 38%. Salah satu penanganan untuk mencegah anemia secara non farmakologi adalah mengkonsumsi sari kacang hijau. Kacang hijau berperan mencegah anemia karena kandungan fitokimia dalam kacang hijau sangat lengkap sehingga dapat membantu proses pembentukan sel – sel darah, eritrosit, leukosit dan trombosit. Tujuan pengabdian kepada masyarakat ini adalah meningkatkan pengetahuan dan keterampilan masyarakat untuk pengolahan sari kacang hijau yang dapat digunakan untuk pencegahan anemia ibu hamil. Pada pelaksanaan jumlah peserta yang hadir sebanyak 20 orang. Metode menggunakan penyuluhan terkait pelatihan dan pengolahan kacang hijau menjadi sari kacang hijau serta memantau hasil penyuluhan dan pelatihan kepada ibu hamil dan ibu PKK. Hasil kegiatan pengabdian pada masyarakat terdapat peningkatan pengetahuan dari kuesioner yang dibagikan sebelum pemberian materi yaitu berpengetahuan dengan kategori baik sebesar 40%, kategori cukup sebesar 10%, dan kategori kurang sebesar 50%, sedangkan kuesioner yang dibagikan setelah pemberian materi didapatkan hasil berpengetahuan dengan kategori baik sebesar 75%, kategori cukup sebesar 20%, dan kategori kurang sebesar. 5%]]>
<![CDATA[Breast Self-Examination Education and Training (SADARI) as an Early Detection Effort for Breast Cancer in Women of Childbearing Age ]]>
<![CDATA[Puspita Ningrum, Nyna]]>;
<![CDATA[Ayu Cahya Rosyida, Desta]]>;
<![CDATA[Latifah, Anik]]>;
<![CDATA[Hidayatunnikmah, Nina]]>
<![CDATA[ International Journal of Engagement and Empowerment (IJE2) Vol. 5 No. 2 (2025): International Journal of Engagement and Empowerment ]]>
Publisher : <![CDATA[Yayasan Education and Social Center ]]>
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DOI: 10.53067/ije2.v5i2.218
<![CDATA[Breast cancer is one of the most common types of cancer in women and is the leading cause of cancer death in women in various parts of the world. Early detection is a crucial step in increasing the success of treatment and reducing mortality rates. One easy-to-do early detection method is Breast Self-Examination (BSE), which is an examination carried out independently, regularly, and systematically by every woman to find abnormalities or lumps in the breasts from an early stage. This Community Service (PkM) activity aims to increase the understanding of mothers and young women about the importance of early detection of breast cancer through the BSE method. The activity was carried out in Pengaingan Hamlet, Bangkalan District, involving participants from among students of Madrasah Diniyah Al Munawaroh and local mothers. The methods used included interactive counseling, BSE demonstrations, and question and answer sessions. The results of the activity showed an increase in participants' knowledge about breast cancer and their ability to perform BSE independently. It is hoped that this activity can encourage healthy living behavior and awareness of the importance of early detection as a preventive measure against breast cancer.]]>
<![CDATA[EFFECTS OF SANYINJIAO ACUPRESSURE AND CINNAMON DECOCTION DYSMENORRHEA ADOLESCENTS’ MEAN PLATELET VOLUME ]]>
<![CDATA[Indah Sari]]>;
<![CDATA[Nyna Puspita Ningrum]]>;
<![CDATA[Nina Hidayatunnikmah]]>
<![CDATA[ PROFESSIONAL HEALTH JOURNAL Vol. 7 No. 2 (2026) ]]>
Publisher : <![CDATA[Pusat Penelitian dan Pengabdian Masyarakat (PPPM) STIKES Banyuwangi ]]>
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DOI: 10.54832/phj.v7i2.1279
<![CDATA[Introduction: Dysmenorrhea is a common menstrual pain complaint among adolescent girls affecting physical, psychological, and social activities. According to the World Health Organization (WHO) in 2021, 90% of women worldwide experience dysmenorrhea, and approximately 10–15% suffer from severe cases. One of the biological indicators related to menstrual pain is Mean Platelet Volume (MPV), the average size of platelets in the blood and reflects platelet activity and inflammation. The normal range of MPV is 150.000–400.000 µL, and elevated values may indicate an inflammatory process or acute pain, such as in dysmenorrhea. Objective: To determine the effect of the combination of Sanyinjiao (SP6) acupressure and cinnamon decoction on Mean Platelet Volume (MPV) levels before and after treatment in adolescent girls with dysmenorrhea. Methods: This study used a Pre-Experimental design with a One Group Pre-test and Post-test approach. The sample consisted of 32 adolescent girls with dysmenorrhea, selected using total sampling. The intervention of Sanyinjiao (SP6) acupressure and cinnamon decoction was administered twice daily for five days during menstruation. Results: The mean value of MPV showed a decrease after the intervention, with a p-value of 0.000 (<0.05), indicating a significant effect of the combination of Sanyinjiao (SP6) acupressure and cinnamon decoction on reducing MPV levels in adolescents with dysmenorrhea. Conclusions: The combination of SP6 acupressure and cinnamon decoction was proven to be effective in significantly reducing MPV levels in adolescent girls with dysmenorrhea. This therapy may serve as a practical and safe non-pharmacological alternative to alleviate menstrual pain associated with inflammation.]]>
<![CDATA[The Effect of SP6 Acupressure and Cinnamon Decoction Combination on Hemoglobin in Dysmenorrhea Adolescents ]]>
<![CDATA[kamilia, abidatul]]>;
<![CDATA[Nina Hidayatunnikmah]]>;
<![CDATA[Nyna PuspitaNingrum]]>
<![CDATA[ PROFESSIONAL HEALTH JOURNAL Vol. 7 No. 2 (2026) ]]>
Publisher : <![CDATA[Pusat Penelitian dan Pengabdian Masyarakat (PPPM) STIKES Banyuwangi ]]>
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DOI: 10.54832/phj.v7i2.1280
<![CDATA[Introduction: Dysmenorrhea is a common menstrual pain complaint experienced by adolescent girls. In East Java Province in 2021, around 4,653 adolescents experienced dysmenorrhea, the incidence of primary dysmenorrhea was 4,297 (90.25%). While in Bangkalan around 66.7% experienced dysmenorrhea. Dysmenorrhea can reduce hemoglobin levels due to excessive uterine contractions triggered by prostaglandins. Non-pharmacological therapies such as Sanyinjiao point acupressure (SP6) can stimulate the nervous system and reduce uterine muscle contractions, while cinnamon contains active compounds that are analgesic and anti-inflammatory. Purpose of this study was to determine the effect of the combination of SP6 acupressure and cinnamon decoction on hemoglobin levels in adolescents with dysmenorrhea. Method: uses a one group pretest-posttest design. The study was conducted at the adolescent health post in Karang Asem Village with 32 respondents. The intervention was given twice a day for 5 days of menstruation. Results: showed an increase in hemoglobin levels from an average of 12.20 ± 0.48 gr/dL to 13.75 ± 0.66 gr/dL. The Shapiro-Wilk test showed that the data were normally distributed. The paired t-test produced a p-value of 0.000 (p < 0.05), indicating a significant difference in hemoglobin levels before and after the intervention. Conclusion: is that the combination of SP6 acupressure therapy and cinnamon decoction is effective in increasing hemoglobin levels in adolescents with dysmenorrhea, and can be a practical and safe alternative non-pharmacological treatment.]]>
<![CDATA[Aktivitas Antimikroba Ekstrak Daun Mulberry (Morus Rubra L) Terhadap Penghambatan Pertumbuhan Jamur Candida Albicans-In Vitro ]]>
<![CDATA[Hidayatunnikmah, Nina]]>;
<![CDATA[Latifah, Anik]]>;
<![CDATA[Cahya Rosyida, Desta Ayu]]>;
<![CDATA[Safitri, Sella Dwi]]>
<![CDATA[ JIK-JURNAL ILMU KESEHATAN Vol 6, No 1 (2022): JIK-April Volume 6 Nomor 1 Tahun 2022 ]]>
Publisher : <![CDATA[UNIVERSITAS ALIFAH PADANG ]]>
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DOI: 10.33757/jik.v6i1.513
<![CDATA[Candida albicans merupakan penyebab utama infeksi vagina. Aktifitas antimikroba dan senyawa berry menunjukkan bahwa kandungan anthocyanin dapat melindungi dari bakteri patogen manusia. Pertumbuhan buah mulberry di Indonesia tumbuh secara liar dan pemanfaatnya sedikit oleh masyarakat Indonesia karena kurangnya ketidaktahuan masyarakat terhadap manfaat farmakologis yang di miliki oleh tumbuhan mulberry. Kandungan yang terdapat didalam daun Mulberry adalah alkaloid, flavonoid, dan polifenol. Jenis penelitian yang akan dilakukan ini menggunakan desain penelitian eksperimental laboratories dengan pendekatan Post-Test Only Control Group Design. Penelitian ini dilakukan di Laboratorium Biologi Farmasi Universitas PGRI Adi Buana Surabaya dan Laboratorium Profesor Nidhom Foundation Surabaya. Daun mulberry yang akan diekstrak diambil di tanaman yang ada di Fakultas Sains dan Kesehatan Universitas PGRI Adi Buana Surabaya. Jumlah sampel adalah 8 seri pengenceran ekstrak mulberry (15%, 30%, 45%, 60%, 75%, 80%, 95%, 100%) dalam 4 cawan petri. Tahap Persiapan dialkukan dengan melakunan pembuatan stok bakteri pada media agar serta pembuatan ekstrak daun Mulberry. Cawan petri yang berisi Nutrient Agar dituang dengan suspense Candida albicans dan selanjutnya diberikan ekstrak mulberry dengan 8 seri pengenceran dan diinkubasi selama 24 jam. Hasil menunjukan terdapat zona hambat pada konsentrasi ekstrak mulberry 80%, 95%, 100% pada keempat cawan petri. Kesimpulan terdapat pengaruh ektrak mulberry pada aktivitas antimikroba candida albicans pada konsentrasi ekstrak 80%,95%, dan 100%.]]>
<![CDATA[Cegah Stunting Sejak Dini dengan Makanan Bergizi untuk Ibu Hamil ]]>
<![CDATA[Ningrum, Nyna Puspita]]>;
<![CDATA[Hidayatunnikmah, Nina]]>;
<![CDATA[Rihardini, Tetty]]>
<![CDATA[ E-Dimas: Jurnal Pengabdian kepada Masyarakat Vol 11, No 4 (2020): E-DIMAS ]]>
Publisher : <![CDATA[Universitas PGRI Semarang ]]>
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DOI: 10.26877/e-dimas.v11i4.5616
<![CDATA[Stunting merupakan suatu kondisi yang sangat umum terjadi pada seorang anak dengan kekurangan gizi dikarenakan jumlah makronutrien dan mikronutrien tidak cukup memadai.Indonesia menempati peringkat kelima dunia untuk jumlah anak dengan kondisi stunting.Usaha dini yang dapat dilakukan untuk melakukan pencegahan stunting bisa dilakukan sejak masa kehamilan.Prinsipnya adalah meningkatkan asupan gizi ibu hamil dengan memastikan selama kehamilan ibu mengkonsumsi makanan yang bergizi dan berkualitas baik, oleh karena itu, dibutuhkan suatu penyuluhan untuk meningkatkan wawasan ibu hamil terkait kebutuhan gizi yang baik selama kehamilan dan menambah keterampilan ibu hamil dalam mengelola makanan yang kaya akan gizi. Target khusus pada kegiatan masyarakat ini adalah ibu hamil dan kader kelurahan. Metode yang diterapkan pada kegiatan ini adalah ceramah/penyuluhan, demonstrasi cara membuat makanan bergizi untuk ibu hamil, dan evaluasi dengan teknik food recall. Hasil akhir pada kegiatan pengabdian masyarakat adalah meningkatnya pemahaman kader dan ibu hamil terkait gizi yang dibutuhkan selama masa kehamilan, serta kemampuan mempraktikkan mengolah makanan yang kaya akan kandungan gizi. ]]>
<![CDATA[PENGARUH PEMBERIAN SIMPLISIA JAHE MERAH TERHADAP INTENSITAS DISMENORE PRIMER PADA REMAJA PUTRI ]]>
<![CDATA[Hidayatunnikmah, Nina]]>;
<![CDATA[Ningrum , Nyna Puspita]]>;
<![CDATA[Prawesty, Priestin Dian]]>
<![CDATA[ Jurnal Kesehatan Ilmiah Aufa Royhan Vol 9 No 2 (2024): Vol. 9 No. 2 Desember 2024 ]]>
Publisher : <![CDATA[Universitas Aufa Royhan ]]>
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DOI: 10.51933/health.v9i2.1840
<![CDATA[Menstruasi adalah perdarahan yang terjadi secara periodik dan siklik, disertai dengan pelepasan (deskuamasi) endometrium. Hampir seluruh perempuan mengalami menstruasi dengan pengalaman nyeri dengan tingkatan yang berbeda. Rasa nyeri yang dialami seperti mual, rasa pegal pada bagian panggul, nyeri perut bagian bawah hingga nyeri yang sakitnya luar biasa. Dismenore mempengaruhi kegiatan sehari-hari yaitu mengurangi kemampuan berkonsentrasi, gangguan belajar dan aktivitas fisik. Dismenore primer banyak dialami oleh para remaja, dismenore primer disebabkan oleh peningkatan produksi prostaglandin dan pelepasannya (terutama PGF2α). Salah satu alternatif untuk mengatasi dismenorea primer secara non farmakologi dengan pemberian simplisia jahe merah. Senyawa gingerol dan shogaol yang terdapat dalam jahe efektif mengurangi rasa sakit, sebagai anti-inflamasi dengan menghambat kerja enzim dalam siklus cyclooxygenase (COX) dan lipooxygenase sehingga dapat menghambat dilepaskannya prostaglandin penyebab inflamasi dan menghambat kontraksi uterus yang dapat menyebabkan nyeri menstruasi. Tujuan penelitian untuk mengetahui adanya efek pemberian simplisia jahe merah terhadap penurunan intensitas dismenore pada remaja putri di Pondok Pesantren Alibrah Kabupaten Gresik. Penelitian ini menggunakan desain Quasy Exsperimental (Quasy Experimental Design) dengan rancangan two group pretest dan posttest non equivalent control group design, kelompok kontrol (tanpa perlakuan) dan kelompok intervensi diberikan kapsul jahe merah dosis 3 x 1000 mg diminum pada hari pertama sampai dengan hari ketiga menstruasi. Sampel penelitian sebanyak 42 responden, setiap kelompok 21 responden. Teknik pengambilan sampel dengan Purposive Sampling. Penelitian ini menggunakan uji Independent T test . Hasil penelitian menunjukkan nilai Sig. (2-tailed) 0,000 atau p<0,05 dapat disimpulkan pemberian simplisia jahe merah memiliki pengaruh terhadap penurunan intensitas dismenore pada remaja putri di Pondok Pesantren Alibah Kabupaten Gresik.]]>
<![CDATA[PENGARUH TERAPI FISIK DALAM MENGATASI KENAIKAN BERAT BADAN PADA AKSEPTOR KB HORMONAL ]]>
<![CDATA[Miliana, Lidvina Ochyna Sari]]>;
<![CDATA[Nyna Puspita Ningrum]]>;
<![CDATA[Nina Hidayatunnikmah]]>
<![CDATA[ Jurnal Medicare Vol. 4 No. 4 (2025): OCTOBER 2025 ]]>
Publisher : <![CDATA[Rena Cipta Mandiri ]]>
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DOI: 10.62354/jurnalmedicare.v4i4.268
<![CDATA[Weight gain is a common side effect among hormonal contraceptive users, potentially leading to dissatisfaction, discontinuation, and long-term health risks. This study aimed to determine the effect of physical therapy in overcoming weight gain among hormonal contraceptive acceptors. This quantitative research employed a one-group pretest-posttest design, conducted at TPMB Affah Fahmi, Surabaya, in April–May 2023 with 31 respondents selected through purposive sampling. The intervention consisted of structured physical therapy sessions, three times a week for four weeks, involving aerobic exercise, stretching, and light strength training. Weight was measured before and after intervention, analyzed using paired t-test (p < 0.05). Results showed a significant decrease in average body weight from 57.44 ± 3.45 kg to 55.63 ± 3.26 kg (p = 0.000).]]>
<![CDATA[Utilization of Mulberry Leaf Decoction (Morus Alba L.) as a Traditional Treatment for Fluor Albus in Women of Childbearing Age ]]>
<![CDATA[Solichatin, Solichatin]]>;
<![CDATA[Ningrum, Nyna Puspita]]>;
<![CDATA[Hidayatunnikmah, Nina]]>;
<![CDATA[Rosyida, Desta Ayu Cahya]]>
<![CDATA[ Shihatuna : Jurnal Pengabdian Kesehatan Masyarakat Vol 5 No 2 (2025): Desember ]]>
Publisher : <![CDATA[FKM UIN Sumatera Utara Medan ]]>
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DOI: 10.30829/shihatuna.v5i2.26337
<![CDATA[Fluor albus, or pathological vaginal discharge, is a common reproductive health disorder experienced by women of childbearing age (WUS). The primary cause is often related to Candida albicans fungal infection. Azole-based pharmacological therapy is known to be effective, but has the potential to cause resistance and side effects. This community service activity aims to improve the knowledge and skills of WUS in the Keputran Village, Surabaya, regarding the use of mulberry leaf decoction (Morus alba L.) as an alternative herbal treatment for fluor albus. The activity included health education, demonstrations on how to make herbal concoctions, and evaluation of participants' knowledge through discussions and questions and answers. The results showed a 90% increase in community knowledge regarding the prevention and treatment of fluor albus, and 85% of participants expressed interest in implementing this herbal treatment. This activity demonstrates that community empowerment through an educational approach and hands-on practice can increase awareness and independence in maintaining women's reproductive health naturally and sustainably.]]>
