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All Journal Public Health of Indonesia Jurnal Penelitian Pendidikan IPA (JPPIPA) JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Farmamedika (Pharmamedica Journal) Jurnal Ilmiah Farmasi Farmasyifa Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Penelitian Farmasi dan Herbal Jurnal Ilmiah Jophus: Journal of Pharmacy UMUS Journal of Pharmaceutical and Health Research Jurnal Kesehatan Tambusai INPHARNMED Journal (Indonesian Pharmacy and Natural Medicine Journal) Proceedings Series on Health & Medical Sciences Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Parapemikir Jurnal Ilmiah Farmasi CERATA Jurnal Sains, Teknologi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian
Abdul Wahid Suleman
Universitas Megarezky
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Engineering Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Veterinary

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Journal : CERATA

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The Comparison and Test of Antioxidant Activity of Ethanol Extracts of Pangi Leaves and Seeds (Pangium Edule Reinw.) Using the DPPH (1,1-Diphenyl-2-Picrylhydrazyl) Method Suleman, Abdul Wahid; Sari, Nurmala; Safaruddin, Safaruddin; Adri, Tenri Ayu; Siradjuddin, Mutmainnah; Prihandari, Ayu
CERATA Jurnal Ilmu Farmasi Vol 15 No 2 (2024): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v15i2.988

Abstract

The leaves and seeds of pangi (Pangium edule Reinw.) contain alkaloids, flavonoids, saponins, and tannins, which acts as antioxidants. Antioxidants are needed to protect the body and inhibit the negative impact of free radicals due to the oxidation reactions that occur. Antioxidants are compounds that inhibit oxidation reactions by binding free radicals and molecules. This research aims to determine the comparison of the antioxidants activity of pangi (Pangium edule Reinw.) leaves and seeds using the DPPH (1,1,-Diphenyl-2-Picrylhydrazyl) method. Reactive research method, experimentally, namely by carrying out serial dilutions of concentrations of 10, 20, 30, 40 and 50 ppm in each test solution, then adding the DPPH solution and measuring the antioxidants activity with a UV-Vis Spectrophotometer. After that, the IC50 (Inhibitor Concentration 50) value and the AAI (Antioxidant Activity Index) value are calculated, and the data were analyzed using ANOVA. The results of calculating the IC50 and AAI values are that the IC50 value of the pangi leaf ethanol extract is 49.6061 ppm (AAI=1.007), while the IC50 value of ethanol extract of pangi seeds is 50.2027 (AAI=0.9959). From the results of research and data analysis, it can be concluded that the ethanol extract of pangi leaves has higher antioxidant activity compared to the ethanol extract of pangi seeds.
The Antibacterial Activity Test of Methanol and N-Hexane Fractions of Yellow Pumpkin Fruit Extract (Cucurbita moschata Duch) Against Escherichia coli and Staphylococcus aureus Suleman, Abdul Wahid; Saparuddin Latu; Sriyanty Sadsyam; Safaruddin; Pradila
CERATA Jurnal Ilmu Farmasi Vol 16 No 1 (2025): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v16i1.1370

Abstract

Infectious diseases are still a major health problem in several countries, especially in developing countries. The medication used to treat bacterial infections is obtained by utilizing herbal plants obtained from natural ingredients. Pumpkin fruit extract (Cucurbita moschata) contains flavonoids. tannins, saponins, and alkaloids Pumpkin fruit is effective as an antidiabetic, an antihypertensive, an antitumor, an antibacterial, and an antioxidant. This study aims to determine the antibacterial activity of the methanol and n-hexane fractions of yellow pumpkin (Cucurbita moschata) fruit extract and at what concentration the methanol and n-hexane fractions of yellow pumpkin (Cucurbita moschata) fruit extract can have antibacterial activity against Escherichia coli and Staphylococcus aureus. This research uses laboratory-experimental research methods. Antibacterial testing in this research involved sterilization, making test solutions, and testing. The results of the antibacterial test on the inhibition zone of the methanol fraction of pumpkin fruit against Escherichia coli and Staphylococcus aureus bacteria at concentrations of 20%, 30%, and 40% were in the strong category, while the n-hexane fraction had an inhibition zone in the weak category for Escherichia coli and Staphylococcus aureus bacteria. Conclusion: The methanol and n-hexane fractions have antibacterial activity against Escherichia coli and Staphylococcus aureus, and the concentrations with antibacterial activity are 20%, 30%, and 40%.
Co-Authors A. Nurnadya Arna Abda Abda Ardiansyah Habar Besse Yuliana Chikita Inaku Herman, Sriyana Indra, Sri Rahayu Putri Irwan Irwan Jangga Jangga, Jangga Mahmudah, Rifa’atul Mansur Maria Fenesia Fangohoi Miftahul Jannah Muhammad Yusuf Muhammad Yusuf Mustamin, Sharnawati Najamuddin, Mirfaidah Nanik Sulistyani Ni Wayan Kamariasih Ningsih Samsy Dhuha Nova Clarita Dama Nurhikmah Nurkhasanah Mahfudh Nurmala Sari Nurul Inayah Padjalangi, Andi Muh Yagkin Padjalangi, Andi Muhammad Yaqkin Patti, Seliana Pradila Pratiwi, Elzha Meilya Pratiwi, Rizky Indah Prihandari, Ayu Putri, Hardyanti Eka Rizky Indah Pratiwi Rizky Indah Pratiwi, Rizky Indah RR. Ella Evrita Hestiandari Rusli Safaruddin Safaruddin Safaruddin, Safaruddin Saparuddin Latu Sari, Putri Indah Siradjuddin, Mutmainnah Sri Wahyuningsih Sri Wulan Rini Sriyanty Sadsyam Sulaiman Syamsidar Tahirah Hasan Tenri Ayu Adri Tri Handayani Ummu Kalsum Wahid, Hilmiati Wahyuni Wahyuni Yanti Puspitasari Yusuf, Muhammad Zahira, Saliza