Garuda - Garba Rujukan Digital

p-Index From 2021 - 2026

2.844

P-Index

This Author published in this journals

All Journal bionature Science and Technology Indonesia Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Jurnal Fitofarmaka Indonesia As-syifaa Jurnal Farmasi Window of Health : Jurnal Kesehatan PREPOTIF : Jurnal Kesehatan Masyarakat Pharmaceutical Reports Journal Microbiology Science MPSJ

Tadjuddin Naid

Laboratorium Kimia Farmasi, Fakultas Farmasi, Universitas Hasanuddin, Makassar

Author-ID : 327678

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Veterinary

Published : 29 Documents Claim Missing Document

Claim Missing Document

Articles

1 2 3

Validated Chromatography Method for Analysis of Formaldehyde Migration Levels in Bottled Drinking Water Ramadhani, Nur; Yulianty, Risfah; Rifai, Yusnita; Aswad, Muhammad; Alam, Gemini; Naid, Tadjuddin; Kasim, Athia Kurnia
Science and Technology Indonesia Vol. 9 No. 3 (2024): July
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2024.9.3.660-668

Polyethylene terephthalate (PET) is utilized in the containment of potable water, nonetheless, it is susceptible to impairment due to temperature and duration of storage. Migration of formaldehyde from PET arises as a consequence of thermal deterioration. This study aims to ascertain the extent of formaldehyde transference in PET-contained drinking water of varying condition, subjected to diverse temperature setting and storage durations. An examination into the levels of formaldehyde migration in polyethylene terephthalate (PET) bottled drinking water was effectively carried out employing a validated high-performance liquid chromatography (HPLC) technique. A total of 162 water samples from three different PET bottled water brands sourced from supermarkets in Palu City, Central Sulawesi, Indonesia, underwent analysis. The formaldehyde assessment was executed utilizing a mobile phase composition of methanol:acetonitrile:water (48:12:40 v/v) for 12.97 minutes at a flow rate of 0.8 mL/minute on the 1st day, the 14th day, and the 42nd day while stored at room temperature and exposed to sunlight. Formaldehyde, lacking effective chromophoric entities and not readily ionizable, necessitated derivatization with 2,4-dinitrophenylhydrazine before HPLC analysis. The findings of the study demonstrated exceptional method linearity within the concentration span of 0.5 to 1321 µg/mL, exhibiting a commendable correlation coefficient of 0.999. The limit of detection (LOD) and quantification (LOQ) were determined to be 17.33 and 57.76 µg/mL, correspondingly. Precision evaluations displayed average intraday and interday values of 128.46±3.48% and 103.19±0.12%, respectively (%RSD < 2/3 CV Horwitz ratio). The intraday and interday %recovery values were computed at 97.22±3.48% and 96.83±0.14% (n = 6). The scrutiny of formaldehyde concentrations in the water samples unveiled the absence of formaldehyde migration.

IDENTIFICATION AND ANTIBACTERIAL ACTIVITY TEST OF ENDOPHYTE FUNGI MAHONI BARK (Swieenia mahagoni L.) IFKBM04 Nuryanti, Siska; Rosdah, Rosdah; Naid, Tadjuddin; Hardiyanti, Vivi
Journal Microbiology Science Vol 1, No 1 (2021)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Endophytes represent a complex community of microorganisms colonizing asymptomatically internal tissues of higher plants. Several reports have shown that endophytes enhance the fitness of their host plants by direct production of bioactive secondary metabolites. This study investigated the antibacterial activity of endophytes fungi IFKBM04 isolated from Swietenia mahagoni L. and identified macroscopic and microscopic characteristics of endophytic fungi. Based on the results of macroscopic and microscopic identification compared with the literature to determine the general characteristics of the sample. The results of this morphological identification showed that the sample of mahogany bark isolate (Swietenia mahagoni L.) code IFKMB-04 had similarities with the genus Saccharomyces sp.

Evaluation of Ethanol Extract Tapak Dara Leaf (Catharanthus roseus L. ) for Antibacterial Activity against Skin Pathogens Alhijrah, Yayu; Naid, Tadjuddin; Nuryanti, Siska
Journal Microbiology Science Vol 4, No 1 (2024)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jms.v4i1.1006

Tapak dara leaves (Catharanthus roseus L.) are known to be efficacious for relieving muscle pain, antidepressants, as well as medicine for various diseases such as relieving swelling from wasp stings, nosebleeds, and sore throats, antidotes, antibacterials, and lowering blood pressure in humans because they contain chemical compounds such as essential oils, phenolic acids, flavonoids, tannins, and alkaloids. This study aims to determine the antibacterial activity of the ethanol extract of tapak dara leaves against bacteria that cause skin infections. This type of research is done in an experimental laboratory using the agar diffusion method, which is based on inhibiting the growth of bacteria that cause skin infections. The stages of this research began with sample preparation, screening for antibacterial extract activity, and testing the antibacterial extract activity at several concentrations against the test bacteria that cause skin infections. This study obtained the results that the ethanol extract of tapak dara leaves tested positive for inhibition of the growth of Staphyloccus aureus, Staphylococcus epidermidis, Pseudomonas aeroginosa, and Propionibacterium acne based on the extract screening results. The results of this study also showed that the ethanol extract of tapak dara leaves at a concentration of 40% had the greatest inhibition using the agar diffusion method based on the diameter of the inhibition zone, with a value of 8.37 mm (Propionibacterium acne); 8.47 mm (Pseudomonas aeruginosa); 9.19 mm (Staphylococcus epidermidis); and 11.68 mm (Staphylococcus aureus)

IDENTIFIKASI KOMPONEN KIMIA EKSTRAK ETANOL DAUN PACAR KUKU (Lawsonia inermis L.) SEBAGAI ANTIBAKTERI DAN ANTIOKSIDAN Herwin, Herwin; Nurung, Ayyub Harly; Ambon, Nur Intan; Naid, Tadjuddin
Journal Microbiology Science Vol 2, No 1 (2022)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Prevention of the transmission of covid 19 can be done by implementing the health protocol, namely 3M (wearing masks, washing hands and social distance). Based on research, the use of masks can reduce the risk of transmission of COVID-19 by 45 percent as well as hand washing reduces the risk by 35 percent. WHO recommends washing hands with soap/antiseptic for 20-30 seconds and applying the right steps. Another effort is to maintain a distance of at least 1 meter and avoid crowds. To assist the government in preventing the transmission of covid 19, socialization of the 3M activity was carried out at the Darul Istiqamah Maros Islamic Boarding School which is located on the Maros-Makassar Street, Mandai District, Maros Regency. This location was chosen because Maros was the third highest area with the number of people who are positive for the corona virus in South Sulawesi. Islamic boarding school students are a partner group that is expected to apply the 3M health protocol so as to prevent the transmission of covid 19. The activity is carried out by providing counseling about the importance of implementing 3M, how to implement 3M and also by distributing masks, soap and disinfectants needed to implement health protocols. The activity was carried out well and received a good response from the participants with 33 participants from various classes who were students of the Darul Istiqamah Islamic Boarding School Makassar.

Antioxidant Activity of Dechlorophyllation of Kejibeling Leaf (Strobilanthes crispu L.) Extract Using the Free Radical Reduction Method Marda, Marda; Naid, Tadjuddin; Rahmawati, Rahmawati
Pharmaceutical Reports Vol 3, No 1 (2024): (March) Pharmaceutical Reports
Publisher : Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/pharmrep.v3i1.285

Kejibeling leaves (Strobilanthes crispus L.) from the Acanthaceae family is a medicinal plant that has medicinal properties. This research aims to determine and determine the antioxidant activity of the dechlorophyllation ethanol extract of kejibeling leaves (Strobilanthes crispus L.) based on the IC50 value with the DPPH method. Kejibeling leaf extract (Strobilanthes crispus L.) extracted by soxhletation method, wherein the extraction process uses two types of solvents of different polarity, to attract chlorophyll compounds and antioxidant compounds, the percent yield of chlorophyll extract is obtained 0.0352% and percent yield of dechlorophyllation ethanol extract 9.604%. Then tested the antioxidant activity using the DPPH method. The results showed that there was antioxidant activity with an IC50 value of 106.375 µg/mL, that is, the result shows moderate antioxidant activity, while quercetin as a comparison has very strong antioxidant activity with a value of 1.391 µg/mL.

ANALISIS HUBUNGAN TINGKAT KEPUASAN PASIEN DENGAN KUALITAS MUTU PELAYANAN KEFARMASIAN DI INSTALASI FARMASI RUMAH SAKIT UMUM DAERAH DAYA KOTA MAKASSAR Palongko, Siska Oktavina S.; Naid, Tadjuddin; Mirawati, Mirawati
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 8 No. 3 (2024): DESEMBER 2024
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v8i3.38963

Kepuasan pasien merupakan merupakan indikator penting dalam pelayanan kefarmasian dan erat kaitannya dengan kualitas pelayanan. Kualitas pelayanan yang baik akan memberikan kepuasan kepada pasien sehingga mempengaruhi pasien untuk kembali lagi ke rumah sakit. Penelitian ini bertujuan untuk mengetahui tingkat kepuasan pasien terhadap kualitas mutu pelayanan kefarmasian serta hubungan kualitas mutu pelayanan kefarmasian terhadap kepuasan pasien di Rumah Sakit Umum Daerah Daya Kota Makassar. Penelitian merupakan penelitian kuantitatif dengan desain penelitian deskriptif non-eksperimental menggunakan kuesioner yang diberikan kepada 318 pasien. Hasil penelitian menunjukkan bahwa 91,19% kualitas mutu pelayanan kefarmasian sangat baik, sedangkan pada tingkat kepuasan pasien mengunakan model servqual menunjukkan bahwa pada dimensi tangibles berada pada kategori sangat puas (83,15%), reliability sangat puas (81,46%), responsiveness puas (79,07%), emphaty puas (80,11%) dan assurance sangat puas (82,86%). Dari analisis data dengan menggunakan metode Chi-square terkait hubungan kualitas mutu pelayanan kefarmasian terhadap kepuuasan pasien di Rumah Sakit Umum Daerah Daya Kota Makassar didapatkan nilai probabilitas sig?0,05 yaitu sebesar 0,047 yang artinya terdapat hubungan yang signifikan antara kedua variabel tersebut.

Antibacterial Activity Test of Ceremai Leaf Ethanol Extract (Phyllanthus acidus (L.) Skeels) Against Bacteria Causing Skin Infections by KLT-Bioautography and Agar Diffusion Naid, Tadjuddin; Herwin, Herwin; Muldin, Nurul Insani
Journal Microbiology Science Vol 5, No 1 (2025)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jms.v5i1.1204

Ceremai leaves (Phyllanthus acidus) are known for their medicinal properties, including the treatment of infectious diseases. This study aims to evaluate the antibacterial activity of ethanol extract from Ceremai leaves against skin infection-causing bacteria using Thin Layer Chromatography-Bioautography (TLC-Bioautography) and agar diffusion methods. The study began with an antibacterial screening test, followed by TLC-Bioautography, and then determination of the Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) at various concentrations (0.125% to 16%). The agar diffusion method was used to further assess antibacterial activity. Screening results showed antibacterial activity at a concentration of 1%. TLC-Bioautography with a chloroform: methanol: water (20:2:0.5) eluent revealed active spots with Rf values of 0.8, 0.54, 0.36, and 0.29. The MIC values were 0.25% for P. acnes and S. aureus, and 0.5% for P. aeruginosa and S. epidermidis. The MBC values were 0.5% for P. acnes and S. aureus, and 1% for P. aeruginosa and S. epidermidis. The largest inhibition zone in the agar diffusion test was observed at a 32% concentration against S. aureus, measuring 20.11 mm. These findings suggest that Ceremai leaf extract has significant antibacterial potential and could be considered for developing alternative treatments for skin infections.

Antimicrobial Activity of Ethanol Extract of Pinang Seed (Areca catechu L.) Against the Growth of Candida albicans and Malassezia furfur Fungi Using the Agar Diffusion Method Naid, Tadjuddin; Saputri, Febrianti Ayu; Nuryanti, Siska
Journal Microbiology Science Vol 5, No 1 (2025)
Publisher : Fakultas Farmasi, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jms.v5i1.1229

Pinang seeds (Areca catechu L.) are known for their various benefits, including antimicrobial properties. This study aims to evaluate the antimicrobial activity of ethanol extract from pinang seed against the growth of Candida albicans and Malassezia furfur fungi using the agar diffusion method. The research involved extracting the pinang seed using maceration with 96% ethanol, followed by evaporation using a rotary vacuum evaporator to obtain a concentrated extract. Antimicrobial activity was tested across concentrations of 32%, 16%, 8%, 4%, 2%, 1%, 0.5%, and 0.1%. The results showed that at a concentration of 32%, the ethanol extract produced the largest inhibition zones: 27.78 mm against Candida albicans and 15.51 mm against Malassezia furfur, both categorized as very strong activity. These findings suggest that ethanol extract of pinang seed has significant potential as an antimicrobial agent, particularly against fungal pathogens.

Analisis Cemaran DNA Tikus pada Bakso Daging Sapi yang Beredar di Makassar dengan Metode Polymerase Chain Reaction (PCR): Analysis of Rat DNA Contamination on Beef Meatballs Circulating in Makassar by Polymerase Chain Reaction (PCR) Method Aminah, Aminah; Ramadini, Ristieyen; Naid, Tadjuddin
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 5 No. 1 (2019): (March 2019)
Publisher : Universitas Tadulako

Analysis of rat DNA contamination in meatball meat circulating in Makassar by PCR (Polymerase Chain Reaction) method has been carried out. In this study, a polymerase chain reaction method will be developed to analyze the presence of rat meat contamination in beef meatballs. There are three stages in the PCR amplification process carried out with 30 cycles, which are 95oC temperature denaturation, 51oC attachment, and 72oC extension. DNA analysis included agarose gel electrophoresis, measurement of concentration and purification, and analysis of rat DNA using PCR. The results of PCR amplification using mouse-specific primers namely primary ND1 (NADH dehydrogenase 1) showed no bands seen in UV light. So that it can be proven that beef meatball samples in the Makassar region did not contain rat DNA. t.

ANALISIS DRUG RELATED PROBLEMS TERHADAP PENGOBATAN KEMOTERAPI PASIEN KANKER PAYUDARA DI RUMAH SAKIT UNHAS MAKASSAR Paduai, Muh. Harry Bagas Setiawan R.; Naid, Tadjuddin; Yuliana, Dewi
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 9 No. 2 (2025): AGUSTUS 2025
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v9i2.48867

Kanker payudara merupakan penyakit yang berkembang sebagai hasil dari kerusakan DNA (Deoxyribonucleic acid) dan mutasi genetik yang dapat dipengaruhi oleh paparan estrogen. Salah satu yang menjadi pengobatan kanker ialah kemoterapi. Tujuan analisis ialah Untuk mengetahui hubungan Drug Related Problems dengan kualitas hidup pada pengobatan pasien kanker payudara di Rumah Sakit Unhas Makassar Periode 2023. Penelitian ini merupakan penelitian deskriptif dengan penyajian data dalam bentuk kualitatif dan kuantitatif dengan pendekatan retrospektif, data diambil dari rekam medis pasien dan administrasi pasien. Teknik sampling ialah purposive sampling dengan diagnosa kanker payudara di Rumah Sakit Unhas Makassar tahun 2023 dan jumlah sampel sebanyak 60 Pasien. Metode analisis data menggunakan analisis drug related problems dengan kategori indikasi tanpa obat,obat tanpa indikasi, dosis terlalu tinggi, dosis terlalu rendah, kontraindikasi, interaksi obat dan efek samping. Berdasarkan hasil penelitian sebanyak 60 pasien kanker payudara di Rumah Sakit Unhas Makassar mengalami Drug Related Problems dengan kategori indikasi tanpa obat sebanyak 1 pasien (2%), obat tanpa indikasi sebanyak 1 pasien (2%), dosis terlalu tinggi sebanyak 6 pasien (10%), dosis terlalu rendah sebanyak 50 pasien (83%), kontraindikasi sebanyak 2 pasien (3%), Interaksi obat sebanyak 60 pasien (100%) dan efek samping sebanyak 12 pasien (20%) dan Terdapat hubungan antara Drug Related Problems kategori efek samping obat dengan Clinical Outcome pasien dengan nilai p= 0.012<0,05 pada kategori kesulitan berjalan dan nilai p= 0,042<0,05 pada kategori mengangkat beban.

Co-Authors A Amaliah Dahlia ABD. MALIK Adelina, Nabila Aisya, A. Henni Alhijrah, Yayu Ambon, Nur Intan Aminah Aminah Andi Maulana Kamri Anggraeni, Nur Afni Anisa, Rianti Asni Amin Bantulu, Ananta Rahayu Dewi Yuliana Dharmawat, Dewi Tri Fitriana Fitriana Fitriani Mangerangi, Fitriani Gemini Alam Hanifah Almahdaly, Hanifah Hardiyanti, Vivi Herwin Herwin, Herwin Irfanitha, irfanitha Kalsum T, Ummu Kasim, Athia Kurnia Kus Haryono Latif, Safira Kartika Handayani Mamat Pratama, Mamat Marda, Marda Mas'ud, Ita Ayuningsih Maulidiyah, Zakiya Mirawati Mirawati Monika, Arum Muhammad Aswad Muldin, Nurul Insani Muzakkir Baits, Muzakkir Nasution, Annio Indah Lestari Nisaa, Nur Rezky Khairun Nur, Wardah Rafidah Nurung, Ayyub Harly Nuryadin, Yudhi Nuryadin, Yudhi Paduai, Muh. Harry Bagas Setiawan R. Palongko, Siska Oktavina S. Qawiy, Haqi Romadhona R. Rusli Rahmawati, Rahmawati Ramadhani, Nur Ramadini, Ristieyen Ramlan, Pratiwi Risfah Yulianty Rosdah, Rosdah Sadjidin, Sugiarto Saputri, Febrianti Ayu Seniwati Dali Seniwati Seniwati, Seniwati Septiyanti, Septiyanti Siska Nuryanti, Siska Umasangaji, Ria Fitriani Virsa Handayani Yenni Triana, Yenni Yoga Yuniadi Yusnita Rifai, Yusnita Zainal Abidin

Title

Found 29 Documents
Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title Search

Found 29 Documents Search

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Abstract

Title

Found 29 Documents
Search