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All Journal Harmonia: Journal of Research and Education Jurnal NERS Jurnal Farmasi Klinik Indonesia Jurnal Kedokteran HIGEIA (Journal of Public Health Research and Development) Health Notions Biomolecular and Health Science Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Jurnal Ners Visual Heritage: Jurnal Kreasi Seni dan Budaya SURABAYA PHYSICAL MEDICINE AND REHABILITATION JOURNAL CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Indian Journal of Forensic Medicine & Toxicology Jurnal Ilmiah Multimedia & Komunikasi Indonesian Archives of Biomedical Research (InABR) Indonesia Journal of Physical Medicine and Rehabilitation Indonesia Journal Physical Medicine and Rehabilitation Sense : Journal of Film and Television Studies Jurnal Ilmu Komputer dan Teknologi (IKOMTI) Widyaparwa Jurnal Penyakit Dalam Indonesia Indonesian Journal of Endocrinology Metabolism and Diabetes (InaJEMD) Folia Medica Indonesiana
Sony Wibisono
Department Of Internal Medicine, Faculty Of Medicine, Universitas Airlangga, Surabaya
Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Serum Receptor Activator of Nuclear Factor-κβ Ligand and Osteoprotegerin Levels and Ratio in Correlation with Bone Mineral Density Fauqa Arinil Aulia; Sri Lestari Utami; Leonita Anniwati; Sony Wibisono Mudjanarko; Ferdy Royland Marpaung
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 27 No. 1 (2020)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v27i1.1627

Abstract

Osteoporosis is a disorder represented by manifestations of low bone mass, decreased bone tissue, and disrupted bone microarchitecture. The diagnosis of osteoporosis so far has been based on fracture manifestations after minimal trauma or by detecting low Bone Mineral Density (BMD). Measurement of Receptor Activator of Nuclear Factor-κβ Ligand (RANKL) and Osteoprotegerin (OPG) levels has opened the discourse of a more specific assessment of osteoblast and osteoclast regulation. The RANKL/OPG ratio can represent resorption and bone formation more significantly when correlated with BMD features. This study aimed to analyze the correlation between serum RANKL and OPG levels and ratio with BMD. A total of 58 post-menopausal females from 13 elderly in Integrated Community Health Care Surabaya and Sidoarjo were enrolled. Data were collected by recording age, onset of menarche, onset of menopause, and Body Mass Index (BMI). Serum RANKL and OPG levels were evaluated using sandwich ELISA from Elabscience®. The RANKL/OPG ratio was obtained from the ratio between measured RANKL and OPG levels in serum. The proximal femur and lumbar spine BMDs were measured using Hologic® Discoveryâ„¢ QDRâ„¢ Dual-Energy X-ray Absorptiometry (DEXA). Pearson's correlation test in this study showed no significant correlation between BMD and RANKL levels (lumbar: p=0.203; hip: p=0.283). The insignificant result was also shown in the correlation between BMD and OPG levels (lumbar: p=0.412; hip: p=0.617). A significant result between lumbar BMD and RANKL/OPG ratio was only found in the osteopenia subjects (p=0.001). The RANKL/OPG ratio had a significant correlation only with osteopenia-BMD in post-menopausal females. Therefore, it could be used as supporting data in osteoporosis screening.
Exogenous Cushing Syndrome: When do We Get the Benefit of Glucocorticoid Stress Dose? Soelistijo, Soebagijo Adi; Gunawan, Hendra; Primasatya, Chandra Adi Irawan; Ariana, Audy Meutia; Mudjanarko, Sony Wibisono; Pranoto, Agung
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 3
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Exogenous cushing syndrome is the most common cushing syndrome found in clinical practice. Its most frequent etiology is the adverse effect of glucocorticoid therapy found in clinical practice or in the form of traditional medicine. The clinical manifestations of exogenous cushing syndrome are similar to the spontaneous counterpart, albeit with the presence of glucocorticoid consumption. We present a case series of exogenous cushing syndrome due to traditional medicine and glucocorticoid consumption with opportunistic infection as its initial manifestation. The first case did not need glucocorticoid supplementation while it was initiated in the second case. Comprehensive management of exogenous cushing syndrome should involve the decision of giving glucocorticoid stress dose, treatment to the underlying disease and education in order to prevent self-glucocorticoid consumption.
Association between the Duration of Steroid Therapy with Hyperglycemia in Patients with Systemic Lupus Erythematosus (SLE) Widyanrika, Farahdiva Audrey; Mudjanarko, Sony Wibisono; Rochmanti, Maftuchah; Ardiany, Deasy; Permana, Putu Bagus Dharma
Current Internal Medicine Research and Practice Surabaya Journal Vol. 5 No. 1 (2024): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v5i1.53043

Abstract

Introduction: Systemic Lupus Erythematosus (SLE) is a systemic autoimmune disease which primary treatment consists of steroid drugs administration. Prolonged steroid administration is often associated with an increase in blood glucose, a condition known as hyperglycemia. Hence, this study aimed to evaluate the association between the duration of steroid therapy with hyperglycemia in patients with SLE treated at a tertiary healthcare center in Surabaya, Indonesia.Methods: A cross-sectional study was conducted under a purposive sampling frame from January to December of 2022 by utilizing secondary data from electronic medical health records in Dr. Soetomo General Academic Hospital, a tertiary healthcare center in Surabaya, Indonesia. The association between variables were analyzed using Fisher's exact test, chi square test, independent T-test, one-way ANOVA, Mann-Whitney, and Spearman's rank correlation.Results: Out of 150 included patients, 2.67% experienced hyperglycemia following steroid therapy for SLE. There were no significant associations between clinical variables and hyperglycemia occurence in SLE patients (p>0.05). Patients that received higher doses of steroid did not experience any significant difference in hyperglycemia (p=0.727 for <6 months; p=0.865 for ≥6 months). Daily steroid dose was also not significantly associated with the severity of SLE manifestations based on the SLEDAI score (p=0.081). Overall, no significant association was identified between the duration of steroid therapy with hyperglycemia among SLE patients in the hospital (p=0.365). Conclusion: The study found no significant correlation between clinical variables, hyperglycemia incidence, daily steroids dosage, methylprednisolone dosage, SLE severity, or steroid use duration in patients with Systemic Lupus Erythematosus.
Association of Serum Magnesium Levels with Matrix metalloproteinase-9 (MMP-9) Urine in Patients with Diabetic Kidney Disease Stage 1 and 2 Rafsanjani, M. Hashemi; Wibisono, Sony; Irwanadi, Chandra
Biomolecular and Health Science Journal Vol. 2 No. 2 (2019): Biomolecular and Health Science Journal
Publisher : Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (258.402 KB) | DOI: 10.20473/bhsj.v2i2.15045

Abstract

Introduction: The progressiveness of stage 1 and 2 kidney disease is indicated by an increase in matrix metalloproteinase-9 (MMP-9). Development of diabetic kidney disease (DKD) is characterized by a thuckening of the glomerular basement membrane followed ultimately by progression to glomerular sclerosis and fibrosis. One of the factors that contribute is magnesium levels. This study aimed to determine the association between serum magnesium levels and MMP-9 urine in patients with stage 1 and 2 DKD.Methods: This was a cross sectional study from stage 1 and 2 DKD patients. Patients were examined for serum magnesium levels and urine MMP-9. Urine MMP-9 examination was taken from the middle portion urine collection and examined using Sandwich-ELISA method then normalized with urine creatinine. The correlation between magnesium and MMP-9 urine was analyzed by the Spearman rank test.Results: This study involved 56 subjects. The mean serum magnesium level was 1.8 ± 0.26 mg/dL. The mean MMP-9 was 120 ng/g creatinin. The mean value of FBG (fasting blood glucose) in patients in the study was 153.29±50.22 mg/dL. The mean value of PPG (post prandial glucose) was 233.61±71.3 mg/dL. The mean HbA1c value was 7.6±1.13%. The mean creatinin serum value was 1.1±0.43 mg/dL. There was a significant negative relationship with a moderate correlation between serum magnesium levels and urine MMP-9 (p = 0.000, r -0.512).Conclusion: There was a significant negative relationship between serum magnesium levels and urine MMP-9 in stage 1 and 2 DKD patients.
Intermedialitas Seni Pertunjukan Dan Lukisan Dalam Adegan Tableau Opera Diponegoro Wibisono, Sony
Visual Heritage: Jurnal Kreasi Seni dan Budaya Vol 6, No 3 (2024): Visual Heritage: Jurnal Kreasi Seni Dan Budaya
Publisher : Universitas Indraprasta PGRI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30998/vh.v6i3.8374

Abstract

Penelitian ini bertujuan untuk mengetahui jenis hubungan lintas media (intermedialitas), dalam adegan tableau pertunjukan Opera Diponegoro. Pertunjukan karya Sardono W Kusumo menampilkan praktik tersebut melalui adegan tableau yang merujuk pada lukisan Penangkapan Diponegoro karya Raden Saleh. Penelitian ini merupakan penelitian deskriptif-kualitatif dengan pendekatan intermedialitas Rajewsky. Pengumpulan data dilakukan melalui observasi dan studi pustaka. Data yang dijadikan bahan penelitian adalah segala unsur dan genre seni yang mengalami proses intermedial dalam pementasan Opera Diponegoro. Analisis dilakukan dengan pencarian praktik-praktik intermedialitas. Hasil penelitian menunjukkan bahwa (1) Adegan tableau Opera Diponegoro mencakup tiga subkategori (tripartit) intermedialitas yakni medial transposition, media combination, dan intermedial reference, meskipun dengan kualitas hubungan yang berbeda-beda. (2) Kategori intermedialitas yang paling kuat adalah subkategori intermedial reference. Praktik ini bukan sekadar sebuah tindakan artistik dalam penyajian seni. Namun, menunjukkan upaya seniman untuk menghadirkan dan menginterpretasi ulang nilai-nilai kepahlawan Pangeran Diponegoro dari medium seni terdahulu ke dalam bentuk medium baru.
Photography as Cinematic Ekphrasis: Intermedial Study in Garin Nugroho’s Opera Jawa Wibisono, Sony
Harmonia: Journal of Arts Research and Education Vol 23, No 1 (2023): June 2023
Publisher : Department of Drama, Dance and Music, FBS, Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/harmonia.v23i1.39633

Abstract

The Opera Jawa (2006), directed by Garin Nugroho is an Indonesian film with unique hybridity of art media (music, dance, visual art installation, acting, photography). This study aims to provide an overview of photographic ekphrasis’s form, process, and function. This research used a descriptive qualitative method. Data collection was through observation with the note-taking documentation technique. Through intermedial studies, data analysis was carried out using Agnes Petho’s cinematic ekphrasis and photo-filmic theory. The results of the study show that Opera Jawa displays the characteristics of intermedial reference media through cinematic ekphrasis of photography in film. This matter is manifested at the diegetic media level through family photos of the character Setyo-Siti, and the extra-diegetic media through photographic frames introducing film characters. Cinematic Ekphrasis works with exchange strategies and crossing the borders of basic media modalities (material, sensory, space-time, semiotic) from film to photography. Cinematic ekphrasis ultimately forms a metaphor that mediates the experience and knowledge of film audiences toward the target media and the source media. Thus, Opera Jawa, as the target media, can offer its ideology as a result of Sinta Obong’s source media interpretation.
Obesity and Clinical Outcomes of Acute Decompensated Heart Failure Nuvus, Alviyatul Ainin; Andrianto, Andrianto; Mudjanarko, Sony Wibisono
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 16 No. 1 (2025): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V16I12025.70-75

Abstract

Highlights: Clinical outcomes in obese acute decompensated heart failure patients were found to be better than those of non-obese patients but not statistically significant. Acute decompensated heart failure patients were dominated by males.   Abstract Introduction: Obesity is an independent risk factor that raises the prevalence of heart failure, but it is paradoxically associated with a better prognosis. This study examined the relationship between obesity and clinical outcomes of acute decompensated heart failure at Dr. Soetomo General Academic Hospital, Surabaya. Methods: This was an analytic observational study using a prospective cohort design. Patients with acute decompensated heart failure who were admitted to the inpatient care unit of Dr. Soetomo General Academic Hospital, Surabaya, from December 2021 to July 2022 were chosen using a purposive sample technique. The data were analyzed using the International Business Machines Corporation (IBM) Statistical Package for Social Sciences (SPSS) version 26.0. Results: There were 58 patients (n=58) representing different categories, with an average age of 55 years old, and were predominately males (58.6%). This study found that clinical outcomes in obese acute decompensated heart failure patients were better than those of non-obese patients in terms of shorter lengths of stay (p=0.825), lower rates of rehospitalization (p=0.458), and lower rates of all-cause mortality (p=0.673). Conclusion: The difference between the clinical outcomes in obese acute decompensated heart failure patients and non-obese patients was not statistically significant.
Analisis AWS, Microsoft Azure, dan GCP terhadap Latency, Throughput, IAM, dan Firewall Islam, Ichsani; Setiawan, Antonius; Jaenul, Ariep; Mulyono, Sidik; Hertin, Revita; Wibowo, Aryo; Nisa, Khoirun; Wibisono, Sony
Jurnal IT UHB Vol 6 No 2 (2025): Jurnal Ilmu Komputer dan Teknologi
Publisher : Universitas Harapan Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35960/ikomti.v6i2.1795

Abstract

This study evaluates the performance and security of Amazon Web Services (AWS), Microsoft Azure, and Google Cloud Platform (GCP) through technical testing and user experience surveys. Testing with Apache JMeter reveals that GCP has the highest throughput (61.7 bps) and best speed, while AWS has the lowest response time (38.16 ms) and Latency (507 ms). Performance data is presented in tables and graphs. In terms of security, AWS and Azure offer comprehensive features including role-based access control and multi-factor authentication, while GCP emphasizes network protection. Reliability analysis using Cronbach’s Alpha indicates excellent internal consistency (α > 0.9), with ANOVA tests showing significant differences in Throughput, Speed, and Firewall among providers, while other parameters show no significant differences. The findings provide insights into the strengths and weaknesses of each Cloud service provider.
Fasciitis Necroticans pada Diabetes Melitus: Sebuah Laporan Kasus Cahyanti, Reni Ika; Martiniani, Endang; Wibisono, Sony; Herawati, Fauna
Indonesian Journal of Clinical Pharmacy Vol 14, No 2 (2025)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/ijcp.2025.v14i2.58295

Abstract

Fasciitis necroticans (FN) adalah penyakit langka penyebab nekrosis jaringan lunak secara cepat dan berpotensi menyebabkan sepsis akut hingga kematian. Diabetes merupakan salah satu faktor risiko terjadinya FN. Laporan kasus ini membahas diagnosis dini dan terapi pasien FN dengan diabetes. Seorang pria 54 tahun dengan diabetes selama 3 tahun, rutin mengonsumsi obat antidiabetes oral, dan memiliki riwayat amputasi jari kelingking kiri, didiagnosis FN pada kaki kiri. Diagnosis ditegakkan pada hari pertama perawatan dengan skor LRINEC 9. Pasien mendapat terapi injeksi seftriakson 1 gram tiap 12 jam dan metronidazol 500 mg tiap 8 jam, disertai kultur pus. Setelah 5 hari pengobatan, kadar leukosit tetap tinggi, dan kondisi belum membaik. Kultur pus sensitif terhadap seftriakson, tetapi pada hari ke-9 nilai leukosit meningkat menjadi 21,96 x 103/µL, sehingga antibiotik diganti menjadi injeksi sefoperazon sulbaktam 1 gram tiap 12 jam. Dua kali injeksi berhasil menurunkan leukosit menjadi 9,04 x 103/µL, suhu tubuh normal, dan nyeri berkurang, menunjukkan sensitivitas seftriakson bersifat intermediate dibanding sefoperazon-sulbaktam. Pembedahan dan perawatan luka bertekanan negatif tinggi meningkatkan perbaikan klinis. Pasien menolak amputasi dan meminta pulang. Pasien datang kontrol 5 hari kemudian dan direncanakan untuk rawat luka ulang. Namun, pasien meninggal sebelum jadwal kontrol berikutnya. Diagnosa dini, pemberian antibiotik, dan tindakan pembedahan dengan rawat luka intensif sangat penting untuk manajemen keberhasilan terapi FN dan merupakan tantangan yang perlu dipelajari lebih lanjut.
Risk Factor Pattern of Graves’ Ophthalmopathy at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia Akbar, Royhan; Mudjanarko, Sony Wibisono; Komaratih, Evelyn; Ardiany, Deasy
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 16 No. 2 (2025): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V16I22025.162-167

Abstract

Highlights: Female patients are more likely to suffer from GO. Most GO patients have high thyroid levels (hypothyroidism).   Abstract Introduction: Graves' ophthalmopathy (GO) is an autoimmune condition that extends beyond the thyroid gland. The development of GO may be influenced by various risk factors, some of which may interact with each other. This study aimed to identify the most prevalent risk factors for patients with GO from 2019 to 2022 at Dr. Soetomo General Academic Hospital, Surabaya. Methods: This study employed a descriptive cross-sectional design, examining 150 patients who met the inclusion and exclusion criteria. This study measured the age, gender, and systemic thyroid status of all patients. This study used Microsoft Word and Microsoft Excel for Mac version 16.87 to process data. Results: Between 2019 and 2022, 150 patients were diagnosed with GO at Dr. Soetomo General Academic Hospital, Surabaya. The condition was more prevalent in females than males, and the most common age group affected was between 30 and 50 years old. Additionally, 72% of patients with GO also had hyperthyroidism. Conclusion: Graves' ophthalmopathy was more prevalent in female patients, aged between 30 and 50 years old, with the majority having hyperthyroidism. Future studies should be conducted on the patterns of GO risk factors on a larger scale to more accurately represent the disease in the general population.
Co-Authors , ANDRIANTO Agung Pranoto AGUNG PRANOTO Agustianto, Rafiv Fasya Akbar, Royhan Al arif, Mohammad Anam Andrianto Andrianto Andrianto Ardiany, Deasy Ariana, Audy Meutia Ariep Jaenul Arifoel Hajat Askandar Tjokroprawiro Audy Meutia Ariana Bambang Hermanto Bambang Purwanto Budi Prasetyo Cahyanti, Reni Ika Cantika Putri Melyana Chandra Adi Irawan Primasatya Chandra Irwanadi, Chandra Damayanti Tinduh Desi Rianti Rahmadhani Dian W Astuti Emmy Amalia Farahiyah, Jihaan Fauqa Arinil Aulia Febri Kurniawati Ferdy Royland Marpaung Gusti Agung Ayu Ira Kencana Dewi Hanestya Oky Hermawan Hanestya Oky Hermawan, Hanestya Oky Hendra Gunawan Herawati, Fauna HERAWATI, LILIK Hermifa Dwi Aninnaimah Hermina Novida, Hermina Hertin, Revita Imam Subadi Indah Wulandari Islam, Ichsani Jayawarsa, A.A. Ketut Karman, Ula Nur Pramesti Khoirun Nisa Komaratih, Evelyn Kurnia Alisaputri Kusnanto Kusnanto Laylatul Fitriah Mukarromah Lefi, Achmad Leonita Anniwati Maftuchah Maftuchah Martha Kurnia Kusumawardani Martiniani, Endang Mas'adah Mas'adah Meity Ardiana Melyana, Cantika Putri Mochamad Wildan mulyono, Sidik Natasha Tiara Bernadette Nur Sulastri Nuvus, Alviyatul Ainin Pawana, I Putu Alit Permana, Putu Bagus Dharma Prabowo, Gwenny Ichsan Primasatya, Chandra Adi Irawan Purwati Rafsanjani, M. Hashemi Rejeki, Purwo Sri Rifki Esa Syahnarki Safira Raissa Dwi Putri SATRIYAS ILYAS Setiawan, Antonius Sidarti Soehita Soebroto, Heroe Soelistijo, Soebagijo Adi Sri Lestari Utami Suksmi Yitnamurti Surdiana Susantio, Karin Ramadhani Thomas Jatiman Titin Puspitasari Ula Nur Pramesti Karman Wibowo, Aryo Widati Fatmaningrum Widyanrika, Farahdiva Audrey Wigati, Kristanti Wanito Winna Adelia Amru Yuli Indah Kurnia