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Formulasi Granul Sarang Walet Putih (Aerodramus fuciphagus) dengan Variasi Kombinasi Maltodextrin dan Povidon Suena, Ni Made Dharma Shantini; Adrianta, Ketut Agus; Wardani, I Gusti Agung Ayu Kusuma; Antari, Ni Putu Udayana
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 14 No. 2 (2022): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1442.836 KB) | DOI: 10.35617/jfionline.v14i2.90

Abstract

Abstract: White swallow nest (SWP) contains Epidermal Growth Factor, which can increase immunity, and glutathione, which functions as an antioxidant. SWP has a high potential to become an antioxidant-rich immunomodulatory drink. Combining maltodextrin and povidone in a granule formula can protect the active substance from heat and maintain the flavor components. However, the wrong concentration can reduce the quality of the resulting granules. This study aims to obtain a combination of maltodextrin and povidone concentrations in SWP granule formulations that produce granules with the best quality and physical stability. The wet granulation method prepared the ten SWP formulas with combined concentrations of maltodextrin-povidone (code: F1 to F10). Evaluation of the physical quality of the granules (organoleptic, pH, soluble time, moisture content, compressibility index, and flow properties) was evaluated on the first, seventh, fourteenth, and twenty-first days. Linear regression is used to create an equation model of the effect of formulation on granule quality parameters. Formula F6 has the lowest compressibility index and the highest flow rate. There was no significant difference for all physical quality parameters of all formulas during storage (p>0.05). The effect of varying concentrations of maltodextrin is inversely proportional to the effect of varying concentrations of povidone on the physical quality of SWP granules. From the research results, it can be concluded that the combination of maltodextrin (5%) and povidone (1%) in F6 produces granules with the best physical quality. All formulas are stable during storage.
The Predisposing Factors to Communicate Effectively in Providing Drug Information Hastama, Ryo; Mendra, Ni Nyoman Yudianti; Antari, Ni Putu Udayana
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 1 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.007028

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Effective communication in providing drug information is essential to achieve the expected outcome in implementing pharmaceutical care. This study aims to analyze factors that influence the occurrence of effective communication in providing drug information. Data were collected using a Likert-scale questionnaire survey technique with a cross-sectional design. The study involved 100 samples from all districts in Denpasar City, which were taken by convenience sampling technique. The characteristics of the respondents are described descriptively. Bivariate and multivariate tests are used to analyze the effect of independent variables on effective communication. The pharmacy atmosphere has no significant impact on effective communication. Pharmacists' technical and interpersonal communication skills can facilitate effective communication on the Chi-squared test, but only the interpersonal communication competencies of pharmacists can encourage effective communication in the logistic regression analysis (p-value 0.008; CI: 95%; OR 4.751: 1.492-15.133). Communication factors, in general, predispose to effective communication. Besides paying attention to the message's contents, pharmacists must pay more attention to how drug information is conveyed to patients. Thus, there is a common understanding between the communicator and the communicant. The patient will also be encouraged to use the drug according to the instructions given so that the ultimate goal of treatment can be achieved.
Formulasi dan Evaluasi Mutu Fisik Lip balm dari Ekstrak Kulit Buah Hylocereus lemairei dengan Variasi Konsentrasi Cera Alba Suena, Ni Made Dharma Shantini; Intansari, Ni Putu Ocha Indira; Suradnyana, I Gede Made; Mendra, Ni Nyoman Yudianti; Antari, Ni Putu Udayana
Usadha Vol 1 No 3 (2022): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36733/usadha.v1i3.5583

Abstract

Red dragon fruit skin (Hylocereus lemairei) contains flavonoid compounds (polyphenols), and vitamins C and E which play the main role as antioxidants, so they are good for moisturizing, nourishing, and maintaining skin health. Lip balm is a cosmetic preparation with main components such as waxes, fats, and oils from natural or synthesized extracts to prevent dryness by increasing lip moisture. The stability of preparation is very important in maintaining the physical quality of the preparation until it reaches the consumer. This study aims to determine the concentration of Cera alba as a stiffening agent needed to produce lip balm preparations of red dragon fruit skin extract (Hylocereus lemairei) with good physical quality. The response observed was the physical quality of the lip balm preparation which included organoleptic, homogeneity, pH, adhesion, and mechanical strength of the lip balm. Data analysis was carried out descriptively. This research begins with the extraction process of red dragon fruit skin using an ultrasonic wave-assisted maceration method using 96% ethanol and 1% HCl. In this study, a lip balm formulation was made from red dragon fruit peel extract with various concentrations of Cera alba 5% (F1), 10% (F2), and 15% (F3) as a stiffening agent. The resulting preparations were stored for 28 days, and their physical quality was observed. The results showed that lip balm preparations F3 produced good physical quality of lip balm preparations during storage. Dragon fruit peel extract can be properly formulated using Cera alba at a concentration of 15% to become a lip balm preparation that has high-quality physical characteristics and has the potential to be developed into a cosmetic preparation that is able to maintain skin moisture, especially the lips.
Tanaman Obat yang Digunakan untuk Menjaga Daya Tahan Tubuh di Desa Ketewel Restuliani, Ni Kadek Ayu; Suwantara, I Putu Tangkas; Antari, Ni Putu Udayana
Usadha Vol 1 No 1 (2021): Usadha: Jurnal Integrasi Obat Tradisional
Publisher : Fakultas Farmasi Universitas Mahasaraswati Denpasar

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pengobatan tradisional merupakan salah satu alternatif pengobatan bagi masyarakat. Pemanfaatan obat tradisional dalam memelihara kesehatan dan mengatasi gangguan penyakit masih dibutuhkan dan perlu dikembangkan, terutama dengan melonjaknya biaya pengobatan dan harga obat-obatan. Oleh karena itu, pengobatan dengan bahan alam yang ekonomis merupakan solusi yang baik untuk menanggulangi masalah tersebut. Desa Ketewel memiliki tradisi unik menjaga daya tahan tubuh terutama bagi anak-anak sehingga penelitia tertarik untuk mengetahui jenis tumbuhan berkhasiat untuk menjaga kesehatan daya tahan tubuh yang digunakan masyarakat Desa Ketewel. Penelitian ini menggunakan metode deskriptif kualitatif. Data diambil melalui wawancara terstruktur, sampel ditentukan berdasarkan sistem saturasi data. Sampel diambil menggunakan teknik snowball sampling menggunakan pedoman kriteria eksklusi dan inklusi. Data hasil wawancara dianalisis secara deskriptif dan. Tanaman obat yang dapat digunakan untuk menjaga daya tahan tubuh yaitu daun katuk ditambah bawang dayak, jahe merah ditambah madu, temu ireng ditambah madu, daun dadap ditambah garam dan daun pandan wangi, daun sambung nyawa ditambahkan garam, daun sembung ditambah garam, jeruk nipis diperas ditambah madu, lemon diperas ditambah madu, buah ciplukan dimakan mentah-mentah, daun sirsak ditambahkan garam, daun kejibling ditambah asam jawa dan garam, daun dani ditambah daun dalu dan ditambah garam, daun kumis kucing diambil segenggam ditumbuk lalu diisi air dan ditambah madu. Ramuan penjaga daya tahan tubuh dalam bentuk parem adalah daun cangging 3 lembar dan jangu 3 yis atau ruas dihaluskan lalu dibalurkan pada tubuh.
Pengaruh Pemberian Informasi Obat terhadap Kepuasan Pasien serta Faktor Pengganggu yang Terlibat di Padangsambian, Bali Sutrisnawati, Ni Komang Ayu Bintang; Agustini, Ni Putu Dewi; Mendra, Ni Nyoman Yudianti; Antari, Ni Putu Udayana
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 13, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.84766

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Providing information when dispensing medicine is a pharmaceutical service that must follow applicable regulations. The best service makes patients satisfied and loyal to the pharmacy. Many things influence patient satisfaction due to varying patient perceptions regarding the quality of pharmacy services. This study aims to analyze the relationship between providing drug information and patient satisfaction, as well as confounding variables. Cross-sectional research was carried out by distributing Likert scale questionnaires and a checklist of types of drug information provided by pharmaceutical staff at the Indobat Padangsambian Pharmacy. The questionnaire was developed from literature studies and has been tested for validity and reliability. A total of 118 respondents who met the criteria were taken using convenience sampling techniques. Data were analyzed using descriptive statistics, chi-square test, and logistic regression. The chi-square test shows that the type of drug information conveyed by pharmaceutical staff is not related to patient satisfaction at the Indobat Padangsambian Pharmacy (p-value 0.580, CI 95%). All variables that are thought to be confounding variables do not have an independent effect on the dependent variable. However, it is known that occupation (health workers and non-health workers) and the patient's proximity to pharmaceutical workers interact and influence patient satisfaction. Pharmacy personnel should provide drug information according to regulations. To make patients satisfied and loyal to the pharmacy, pharmaceutical staff must pay attention to the patient's work background and personal relationship with the patient when providing drug information.
Effective Communication in Providing Medication Information and Patient Satisfaction: A Cross-sectional Survey in Denpasar Noviyanti, Anak Agung Vivi; Antari, Ni Putu Udayana
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 14, No 1
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.86099

Abstract

Background: Pharmacy personnel should provide pharmaceutical care concerning the applicable standards. Furthermore, pharmacy management must consider patient satisfaction to ensure business continuity. Patient subjective factors strongly influence satisfaction. Meanwhile, patient perceptions of pharmaceutical services will change as their experience increases. The pharmacy must improve its services effectively and efficiently. Factors that affect patient satisfaction can assist pharmacies in improving service quality. Effective communication does not require additional resources to improve service quality. The same information can have different effects when presented in different ways.Objectives: Predict the domain of effective communication that influences patient satisfaction.Methods: The cross-sectional survey using a valid and reliable questionnaire was conducted in Denpasar. The research involved 100 pharmacy consumers and was taken with a convenience sampling technique. Data were analyzed descriptively, followed by a Chi-square test and multivariate analysis using logistic regression. The research involved four independent variables: pharmacy atmosphere, pharmacist performance, pharmaceutical technical competence, and interpersonal communication competence. Patient satisfaction is the dependent variable in this study. Results: Communication factors generally affect patient satisfaction in providing drug information. Among all the independent variables tested, interpersonal communication competence plays a significant role in predicting patient satisfaction with a p-value of 0.043 (Logistic regression with 95% confidence level).Conclusion: Patients who perceive pharmacists as having good interpersonal communication competence are 3,133 times more likely to be satisfied. Thus, pharmaceutical staff must train interpersonal communication skills to provide drug information to achieve patient satisfaction outcomes in pharmaceutical services.
Transfer knowledge teknologi formulasi granul untuk diversifikasi produk pengusaha sarang walet Suena, Ni Made Dharma Shantini; Juliadi, Debby; Suradnyana, I Gede Made; Antari, Ni Putu Udayana; Adrianta, Ketut Agus
Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Vol 6 No 2 (2023)
Publisher : University of Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jipemas.v6i2.19396

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Mitra program pengabdian kepada masyarakat ini adalah termasuk dalam kategori masyarakat yang bergerak ke arah ekonomi produktif yang melakukan usaha pengolahan sarang walet berupa jelly konsentrat sarang walet dalam skala industri rumah tangga dengan Merk “Maha Birdnest Bali” yang berlokasi di Denpasar, Bali. Mitra memiliki ternakan sarang walet di daerah Banggai-Sulawesi Tengah. Program pengabdian dengan metode Service Learning ini dirancang untuk memberikan manfaat kepada mitra dalam usahanya memasarkan produk olahan sarang walet dengan menginovasikannya menjadi bentuk granul sarang walet (GSW) yang memiliki ketahanan lebih lama, serta lebih nyaman dan praktis baik saat didistribusikan maupun saat dikonsumsi oleh konsumen. Pelaksanaan program pengabdian berupa transfer knowledge produksi GSW dan pendampingan produksi kepada mitra, serta penyediaan video tutorial produksi GSW bagi mitra. Program pengabdian ini memberikan manfaat nyata bagi peningkatan mutu produk Mitra, dari sisi inovasi bentuk dan rasa, peningkatan ketahanan, dan berpeluang besar meningkatkan omset dan produktivitas mitra. Program pengabdian berencana akan dilanjutkan berupa workshop atau pelatihan produksi GSW dan pengendalian-penjaminan mutu (quality control-quality assurance) bagi tenaga produksi untuk dapat terus menerus memproduksi produk yang berkualitas di tempat usaha mitra.
The Impact of EG and DEG Cases on Sales of Over-The-Counter Syrup Mendra, Ni Nyoman Yudianti; Antari, Ni Putu Udayana; Siada, Nyoman Budiartha; Marwati, I Gusti Ayu
Pharmaceutical and Biomedical Sciences Journal (PBSJ) Vol. 5 No. 2 (2023)
Publisher : Pharmaceutical and Biomedical Sciences Journal (PBSJ)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/pbsj.v5i2.32013

Abstract

The Indonesian Food and Drug Authority (BPOM) investigated and listed safe and unsafe syrup products in response to the contamination of Ethylene Glycol (EG) and Diethylene Glycol (DEG), causing Acute Kidney Injury in pediatric patients. Unsafe products were recalled and removed from distribution, leading to uncertainty and panic among the public and significantly impacting over-the-counter syrup sales in several pharmacies. This retrospective observational study assessed the impact of EG and DEG contamination on the sales of over-the-counter syrup in Pharmacy X in South Denpasar. Data from three months before (August to October 18th, 2022) and three months following the official instruction was published (October 19th, 2022 to December 2022) were analyzed using Wilcoxon test. The findings reveal a staggering decline in the sales of over-the-counter syrup by 35,03% (p-value of 0.03). Moreover, there was a notable increase of prescriptions in powder forms. The contamination cases caused panic, resulting in changes in behavior and consumption patterns. Despite the availability of safety information on an official website, public hesitance toward syrup products persists, indicating the need to implement a more effective strategy to address misinformation and restore public trust. Each individual must be responsible for educating the public during crises to prevent the spread of misinformation, ultimately restoring trust and normal consumer behavior. Furthermore, efficient stock management should be implemented to anticipate potential health crises in the future proactively.
Waspada Penyakit Degenaratif dengan Edukasi Pola Hidup Sehat Antari, Ni Putu Udayana; Suena, Made Dharma Shantini
UNBI Mengabdi Vol. 5 No. 2 (2024): UNBI Mengabdi Juli
Publisher : Universitas Bali Internasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34063/um.v5i2.410

Abstract

Untuk membantu masyarakat meningkatkan literasi kesehatan, terutama mengenai pencegahan penyakit degeneratif, program sosialisasi kesehatan dilakukan di TK Widya Kumara Batubulan. Program ini melibatkan orang tua, guru, dan anak-anak dengan metode ceramah untuk orang tua dan demonstrasi serta bermain peran untuk anak-anak. Kegiatan ini bertujuan untuk memberikan pemahaman tentang pentingnya pola hidup sehat dalam mencegah penyakit degeneratif. Evaluasi menggunakan kuesioner dengan skala Likert menunjukkan bahwa 87,8% peserta berencana untuk membagikan informasi yang diterima kepada orang lain, dan sebagian besar menganggap informasi yang diberikan sangat berguna. Hasil ini menunjukkan bahwa penyuluhan efektif dalam meningkatkan pengetahuan peserta mengenai kesehatan. Program ini diharapkan dapat menjadi model dalam upaya meningkatkan literasi kesehatan masyarakat dan mengurangi prevalensi penyakit degeneratif di masa depan.   To help children develop physical and psycho-social health, parents, teachers, and stake holders should support and guide children by demonstrating good practices. Thus, health workers can assist the community in improving their health literacy through health socialization. Socialization on healthy living to avoid degenerative diseases was held at Widya Kumara Batubulan Kindergarten and attended by parents, teachers, and children of Widya Kumara Kindergarten. Participants were given socialization on degenerative disease knowledge and introduction to the pharmacist profession. The activity used PowerPoint media with a lecture method to help deliver information to parents and demonstration and role-play methods to convey information to kindergarten children. The activity effectiveness assessment questionnaire showed that as many as (30.4%) of participants really understood (48.4%) understood and (21.2%) quite understood the material presented. Most participants considered the information received to be necessary. 87.8% stated that they would explain the information obtained to others. The socialization, delivered using demonstration and role-play methods, also showed the kindergarten children's enthusiasm for the health information presented.
Bilimbi (Averrhoa bilimbi L.) Leaf Extract Cream: Formulation and Efficacy in Accelerating Wound Healing in Male White Mice Suena, Ni Made Dharma Shantini; Nayaka, Ni Made Dwi Mara Widyani; Wardani, I Gusti Agung Ayu Kusuma; Antari, Ni Putu Udayana
Jurnal Kefarmasian Indonesia VOLUME 14, NUMBER 2, AUGUST 2024
Publisher : Pusat Penelitian dan Pengembangan Biomedis dan Teknologi Dasar Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Bilimbi (Averrhoa bilimbi L.) is known for its wound-healing potential due to its flavonoids, saponins, triterpenoids, and tannins. This study aims to develop a practical and stable dosage form of Bilimbi leaf extract, specifically a cream, and evaluate its efficacy as a wound-healing agent. Bilimbi leaf extract at 2% concentration was formulated into a cream with two variations of triethanolamine concentration as an emulsifier, F1 (2%) and F2 (4%). Data were collected through observation and measurement scales during the cream formulation stage. The effectiveness of the cream as a cut wound healer was assessed using a randomized control group pre-test and post-test design. Physical properties, including organoleptic properties, homogeneity, pH, and mechanical stability, were observed, and spreadability was measured. Both formulations met the criteria for creams with good physical quality and effectively reduced the wound length to 0 cm within the 7-day observation period. In contrast, in the control group, wounds still appeared to be 0.4-1 cm in size. In conclusion, the findings in this study indicate that the cream containing 2% Bilimbi leaf extract (Averrhoa bilimbi L.) has favorable physical characteristics and effectively heals incision wounds in male white mice. This formulation shows promise for further development regarding efficacy, safety, stability, and market acceptability.
Co-Authors Achmad Purnomo Achmad Purnomo Agustini, Ni Putu Dewi Alfiana Naili Syirvia Anak Agung Ngurah Dwi Kosalawa Andarista, Ni Kadek Novi Arkhania, Ni Putu Ayu Dhea Aswindari, Ni Nyoman Zelina Debby Juliadi Dewa Ayu Made Adnya Swari Dewi, Ni Putu Leona Yorita Erna Cahyaningsih Fitria Megawati Fitria Megawati Fitria Megawati Gusti Ayu Putu Laksmi Puspa Sari Gusti Bagus Krisna Arum Jati Hastama, Ryo Herleeyana Meriyani Herleeyana Meriyani I Gede Bagaskara Sangging I Gede Made Suradnyana I Gede Wayan Sujarna I Made Agus Sunadi Putra I Putu Tangkas Suwantara I Wayan Mahardika Saputra Intansari, Ni Putu Ocha Indira Jati, Gusti Bagus Krisna Arum Jayanti, Ni Ketut Aprilia Juliari, Ni Putu Hera Kadek Ayu Kartika Putri Ketut Agus Adrianta Ketut Agus Adrianta Komang Tri Candrayani Kosalawa, Anak Agung Ngurah Dwi Lestari, Made Dwik Luh Risma Putri Rahayu Made Dwik Lestari Made Elvenia Ambara Damayanti Made Tarysa Laksmi Dewi Marwati, I Gusti Ayu Megawati, Fitria Mendra, Ni Nyoman Yudianti Meriyani, Herleeyana Ni Kadek Novi Andarista Ni Ketut Aprilia Jayanti Ni Luh Damayanti Ni Luh Wayan Mudia Ariani Ni Made Dharma Shantini Suena Ni Made Dwi Mara Widyani Nayaka Ni Made Puspayanti, Ni Made Ni Nyoman Zelina Aswindari Ni Putu Ayu Dhea Arkhania Ni Putu Ayu Wulan Ningsih Ni Putu Dewi Agustini Ni Putu Dewi Agustini Ni Putu Hera Juliari Ni Putu Kurnia Dewi Ni Putu Leona Yorita Dewi Ni Putu Nadya Kirana Wulandari Ni Putu Sri Devi Chynta Cahyanti Ni Wayan Ari Pertiwi Ni Wayan Ratih Purnama Sari Noviyanti, Anak Agung Vivi Nurul Fatoni Nyoman Ayu Prascitasari Nyoman Budiartha Siada Prascitasari, Nyoman Ayu Putra, I Made Agus Sunadi Putu Era Sandhi Kusuma Yuda Rahadi , I Wayan Surya Restuliani, Ni Kadek Ayu RR. Asih Juanita Sangging, I Gede Bagaskara Saputra, I Wayan Mahardika Sumarni Sumarni Sumarni Sumarni Suradnyana, I Gede Made Sutrisnawati, Ni Komang Ayu Bintang Syirvia, Alfiana Naili Wardani, I Gusti Agung Ayu Kusuma