Claim Missing Document
Check
Articles

Found 3 Documents
Search
Journal : Jurnal Gizi dan Pangan

ANALISIS PROKSIMAT DAN TOKSISITAS AKUT EKSTRAK DAUN SIRIH MERAH YANG BERPOTENSI SEBAGAI ANTIDIABETES Mega Safithri; Farah Fahma; Paramitha Wirdani Ningsih Marlina
Jurnal Gizi dan Pangan Vol. 7 No. 1 (2012)
Publisher : Food and Nutrition Society of Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (207.376 KB) | DOI: 10.25182/jgp.2012.7.1.43-49

Abstract

The aim of this study was to explore the analysis proximate and toxicity of the decoctions of P. crocatum. Fresh leaves of P. crocatum were boiled in water in order to obtain decoction and were examined for its chemical compounds by using SNI 01-2891-1992 method for proximate analysis. Toxicity of decoction extract of P. crocatum was orally fed to rats (Sprague dawley). The results showed that P. crocatum leaves contains 9.27% water, 14.33% ash, 3.96% fat, 22.63% proteins, and 59.08% carbohydrates. Acute toxicity test showed that all rats were still alive after 7 days treatment with P. crocatum decoction for all dose groups (0, 5, 10, and 20 g/kg BB). LC50 value of P. crocatum decoction was 544.82 ppm, meaning that the decoction was relatively harmless and bioactive.
Aktivitas antihiperglikemia ekstrak kulit dan daun surian (Toona sinensis) pada tikus diabetes (Sprague-dawley) yang diinduksi streptozotocin Theresia, Rori; Falah, Syamsul; Safithri, Mega
Jurnal Gizi dan Pangan Vol. 12 No. 3 (2017)
Publisher : The Food and Nutrition Society of Indonesia in collaboration with the Department of Community Nutrition, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (531.996 KB) | DOI: 10.25182/jgp.2017.12.3.187-194

Abstract

This study aimed to examine the antihyperglycemia activity of ethanol extract of 70% on surian bark and leaves on diabetic rats induced with streptozotocin based on body weight, and fasting blood glucose level. Consist of 28 rats are grouped into 7 groups namely normal, negative control, positive control which given glybenclamide with a dose of 3.22 mg/kg bw, bark extract with dose of 150 mg/kg bw, bark extract with a dose of 300 mg/kg bw, leaf extract with dose 150 mg/kg bw and leaf extract with dose 300 mg/kg bw. Diabetogenic mechanisms was conducted with intraperitoneal injection of streptozotocin at  dose of 50 mg / kg bw. This research was conducted experimentally using complete randomized design (RAL) to analyze the results obtained. Bark extract with a dose of 150 mg/kg bw had a better antihyperglycemia activity compared to the other groups which was showed by the decrease of blood glucose level percentage of 72.83% and this group also had ability to maintain body weight was better than the other groups as well as stable feed consumption during research process.
STABILITAS TOTAL FENOLIK, AKTIVITAS ANTIOKSIDAN, DAN AKTIVITAS PENGHAMBATAN α-GLUKOSIDASE PADA MINUMAN FUNGSIONAL BERBASIS SIRIH MERAH (Piper crocatum Ruiz & Pav.) Syaefudin, Syaefudin; Safithri, Mega; Hasanah, Uswatun
Jurnal Gizi dan Pangan Vol. 11 No. 2 (2016)
Publisher : The Food and Nutrition Society of Indonesia in collaboration with the Department of Community Nutrition, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (348.553 KB) | DOI: 10.25182/jgp.2016.11.2.%p

Abstract

This study aims to determine the stability of total phenolic content, antioxidant activity, α-glucosidase inhibitory activity, physical properties (total dissolved solid, pH, color), and total microorganism of antidiabetic functional beverage at certain storage period. The functional beverage made from red betel leaf, cinnamon, and red ginger by using infuse method. Parameters were analyzed for 28 days on 10°C and 30°C of storage temperature. Antioxidant activity was measured by 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, α-glucosidase inhibitory activity was determined in vitro, and total microorganism was measured by total plate count (TPC) method. The results showed that there were increasement in total dissolved solid of 1.92% (10°C) and 3.85% (30°C), and pH values of 15.30% (10°C) and 13.57% (30°C). In contrary, there were decreasement in total phenolic content of 61.63% (10°C) and 79.73% (30°C), antioxidant activity of 46.80% (10°C) and 53.19% (30°C), and α-glucosidase inhibitory activity of 5.43% (10°C) and 0.39% (30°C). Total microorganism at 10oC was <1.0×100 CFU/mL until day 28, while at 30oC was 2.0×100 CFU/mL on day 28. Based on the results, the functional beverage was good in physical and microbiological quality and still have biological activity as an antidiabetic beverage during storage.
Co-Authors . SURYANI Abdul Aziz Abdullah, Wais Achyar, Catellia Auliany Agus Setiyono Akhmad Endang Zainal Hasan Anisa Gianti Zhafira Anna Setiadi Ranti ANNA SETIADI RANTI Athaya, Ardelia Ayu Tri Nursyarah Aziz Syamsul Huda Aziz Syamsul Huda Bella Fatima Dora Zaelani C Hanny Wijaya Cika Hilda Fransiski Destiandani, Khansa Dewi Purnamasari Dimas Andrianto DIMAS ANDRIANTO Dinar Mutiara Hikmah Djarot Sasongko Hami Seno Dwicesaria, Maheswari Alfira Dwitasari, Oczhinvia Dwitasari, Oczhinvia Eka Wahyu Purnama Etik Mardliyati, Etik Fachriyan H Pasaribu Faoziduhu Bawamenewi FARAH FAHMA Febrina, Adella Fernanda Chairunisa Fernanda Chairunisa Fibri Yuniasih, Tiara Fitria Tika Pradita Fitriana S Monisa Fitrilia, Tiana Gholam, Gusnia Meilin Hanif Alamudin Manshur Hasim Hasim Hasim Hendra Susanto Huda, Aziz Syamsul Hudayanti, Martini Husnawati Husnawati Husnawati, . Ilham Gilang Cahya Ahmada Imanniar Yuta Ellana Dittama Indariani, Susi Iriani Setyaningsih Irma Rahmayani Irsal, Riyan Alifbi Putera Kartika, Yayuk Kustiariyah Tarman LAKSMI AMBARSARI Mala Nurilmala MARIA BINTANG Maria Bintang Maulana, Farhan Mere, Janrigo Klaumegio Meydia Meydia Miantika, Shafillah Mita Gebriella Inthe Monita Rekasih Muhammad Assyar Mustika Weni Mustika Weni Mustika Weni Mustopa, Syahrul Mutmainnah Agustiawan Umar Mutmainnah Umar Nabilla, Rahmah Neni Widowati Nirmala Peni Sugiharti Nur Azizah Nusyarah, Ayu Tri Oczhinvia Dwitasari Paramitha Wirdani Ningsih Marlina Pipih Suptijah Pipih Suptijah Prayoga Pannindriya Prayoga Pannindrya Purwanto, Ukhradiya Magharaniq Safira Puspa Julistia Puspita Putri, Azka Adzkya Emalia Putu Kristiani Kalontong Rahadian Pratama Rahmadi Ganesha Putri Raisyadikara, Fadila Rini Kurniasih, Rini Riska Susila Putri Ritonga, Aprilita Putri Defan Riyan Alifbi Putera Irsal Riyan Alifbi Putera Irsal Rizsa Mustika Pertiwi Rori Theresia Rosalina Yuliani Rosyidah, Rara Annisaur Safira P, Ukhradiya Magharaniq Saputra, Rahadita Maura Amanda Sari, Sintia Permata SEDARNAWATI YASNI Septaningsih, Dewi Anggraini Septiyani, Dinie Silitonga, Ria Gusharani Sri Novita Sagita Sulistiyani Susanto, Hendra Susi Indariani Syaefudiin, Syaefudin Syaefudin Syaefudin Syaefudin Syamsul Falah Takeshi Katayama Theresia, Rori Tjahja Muhandri Toshisada Suzuki Umar, Mutmainnah Agustiawan Uswatun Hasanah Vitriyanna Mutiara Yuhendri Wong, Chen Wai Yanti Fajarwati Yundari, Yundari Zaelani, Bella Fatima Dora Zatta Yumni Ihdhar Syarafina