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. Syamsudin
Universitas Pancasila
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Penelitian Terbaru terhadap 3 (Tiga) Jenis Ekstrak Teripang di Pulau Tegal Mas, Lampung Hutapea, Manuel; Swandiny, Greesty Finotory; Syafawi, M. Irfan; Putra, Fahreza Pratama; Kokadir, Sucipto; Basilianus, Edward; Putri, Vinessa Gracia; Abdillah, Syamsudin
JURNAL ILMU KEFARMASIAN INDONESIA Vol 21 No 2 (2023): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v21i2.1447

Abstract

Sea cucumbers are deep-sea-dwelling invertebrate animals that are rich in nutrients and have been empirically used to prevent various degenerative diseases, especially due to their ability to dampen free radicals. The purpose of this study was to identify, and determine antioxidant activity, total phenolic content, and toxic properties in extracts of several sea cucumber species originating from Tegal Mas Island, Lampung. The identification results of the three sea cucumber species were Stichopus vastus Sluiter (SV), Stichopus monotuberculatus Quay & Gaimard (SM), and Stichopus quadrifasciatus Massin. (SQ). The extraction was performed by kinetic maceration against all parts of the sea cucumber using a 70% ethanol solvent. Antioxidant activity test using the DPPH (2,2-diphenylpicrilhydrazyl) free radical suppression method and determination of the total phenolic content using the Folin-Ciocalteu method. The results showed that SV had the highest total phenolics and antioxidants with the lowest toxicity. However, optimisation of extraction between wet and dry sea cucumbers is still required. Extraction optimisation with various solvents can also be done to gain secondary metabolites more effectively.
Co-Authors . Darmono A. Keban, Sesilia Anisa Rachmita Arianti Antonius Antonius Asarini Aulena, Desi Nadya Basilianus, Edward Budi Prasetyo Chandra Wiguna Brata Cyntia Cyntia Deni Rahmat Dian Ratih Laksmitawati Dwi Fitriyani, Dwi Fatty Nurhasanah Fetri Charya Munarsih Ganiswarna S Gemini Alam Greesty Finotory Swandiny Haryo Haryo Hendig Winarno Hermawati, Ema Hikariastri, Pangartika Humairoh Hanan I. W.T. Wibawan Indarwati Indarwati Irma L. M. Kartiningsih Kartiningsih Kokadir, Sucipto Kusmardi Lilik Sulastri Lusi Nursilawati Syamsi MANUEL HUTAPEA, MANUEL Natadidjaja, Ronald Irwanto Nur Rahmi Hidayati, Nur Rahmi Partomuan Simanjuntak Partomuan Simanjuntak Putra, Fahreza Pratama Putri, Vinessa Gracia RAHMAT, DENI Raihan, Dany Riza Darma Putra ROS SUMARNY Sadikin M Sesilia A. Keban Shirly Kumala Sugiastuti, Fenty Suyatna FD Swandiny, Greesty Finotory Syafawi, M. Irfan Yayan Rizikiyan Yulvian Sani Zaidan, Sarah