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All Journal Pharmaciana: Jurnal Kefarmasian Jurnal Pengabdian Masyarakat Kesehatan Indonesian Journal of Chemical Analysis (IJCA) Eksakta : Berkala Ilmiah Bidang MIPA Jurnal Ners Jurnal Riset Kefarmasian Indonesia Lumbung Farmasi : Jurnal Ilmu Kefarmasian BERNAS: Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian kepada Masyarakat Jurnal EduHealth Jurnal Akademika Kimia ASMAT: Jurnal Pengabmas Jurnal ABDI MERCUSUAR Jurnal Pengabdian Pada Masyarakat Nanggroe: Journal Of Scholarly Service Jurnal Katalisator Nanggroe: Journal of Scholarly Service Jurnal Kesehatan dr. Soebandi Journal of Innovative and Creativity Journal of Medical Laboratory in Infectious and Degenerative Diseases Jurnal Akademika Kimia Sadewa: Jurnal Pengabdian Masyarakat Indonesian Pharmacopeia Journal (IPJ) Journal of Pharmacy and Halal Studies (JPHS) Health Media Journal of Pharmaceutical Sciences and Community
Setyaningrum, Lindawati
Pharmacy Program, Faculty Of Health Sciences, Universitas Dr. Soebandi
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Validasi Metode Spektrofotometri UV-VIS Untuk Analisis Formalin Menggunakan Pararosanilline HCL Pada Sampel Plasma Darah Lindawati Setyaningrum
Jurnal Kesehatan dr. Soebandi Vol 7 No 1 (2019): Jurnal Kesehatan dr. Soebandi
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/jkds.v7i1.146

Abstract

Formaldehyde is as a solution containing 30% to 50% formalin with 0.5% to 15% methanol as a polymerization inhibitor. The use of formaldehyde is a sprayer of plants (3%), in order to get harvest is not decayed and withered easily, but it can result residues in plants and crop yields. It can affect in the body health when consumed. Formalin is very dangerous if it accumulates in the body. The safety threshold of formaldehyde in food that enters the body is 1.514 mg/day. Formaldehyde in the drinking water that can be tolerated is 0.1 ppm. Therefore, in this study, the aim was to identify the presence of formaldehyde residues in chili and human blood that consumes the yield of chili contaminated with formaldehyde.. This research was conducted to develop a method for detecting formaldehyde in chilli blood samples as a detection medium for body conditions which were then reacted with pararosanillin HCl. The results of the dark pink reaction followed by detection of the UV-VIS Spectrophotometer method at a wavelength of 539.0 nm. The results showed that this method was able to detect formaldehyde in blood samples with Y = 6.364x - 0.009 and the correlation coefficient (r) of 0.996 and Vx0 < 2, the detection limit was 0.069 ppm and the quantization limit was 0.230 ppm. The accuracy results give an average value of 88.173%. The precision value is expressed as a Relative Standard Deviation of 1.047%. Chili samples collected from around Mount Bromo were detected with the result of a range of formaldehyde concentrati
Efektivitas antihiperkolesterol ekstrak etanol daun salam pada tikus jantan galur wistar diabetes mellitus Shinta Mayasari; Lindawati Setyaningrum
Jurnal Kesehatan dr. Soebandi Vol 10 No 1 (2022): Jurnal Kesehatan dr. Soebandi
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/jkds.v10i1.331

Abstract

Introduction: Cholesterol was one part of fat as one of the nutrients that the body needs and a high calorie producer. Plants made from natural ingredients, for example, bay leaves contain high flavonoids and are hypolipidemic as well as antioxidants that can inhibit oxidative stress. Objective: This study aims to to determine the effectiveness of the ethanol extract of bay leaves (Syzygyum polyanthum) against male white rats wistar strain diabetes mellitus with hypercholesterolemia. Methode: The experimental animals used were male wistar rats induced with streptozotocin at a dose of 30mg/kg BW. The test animals were divided into six groups, each group consisted of 5 rats. Group (I) as a normal control were given standard feed and 0.5% Na CMC, group (II) was given 0.5% Na CMC as a negative control, group (III) was given simvastatin as a positive control, groups (IV) to (VI) were given ethanol extract of bay leaves with a certain dose namely 500mg/kg BW; 750mg/kg BW, and 1g/kg BW.The data obtained were analyzed using One Way Anova statistical test with 95% confidence level. Results: The results of the analysis showed that the p value < 0.005, which means that the ethanolic extract of bay leaf has an effect on cholesterol levels in diabetes mellitus male rats strain Wistar. The effective dose that gives the optimum effect is the ethanolic extract of bay leaf 1g/kgBW. Conclusion: The ethanol extract of bay leaf 1g/kg BW was able to provide optimum antihypercholesterol effects in diabetes mellitus male rats strain Wistar
The Patch Formulation of Rambusa (Passiflora foetida) Leave Extract as Anti-Inflammatory Agent: An In Vitro and In Vivo Study Lindawati Setyaningrum; Aliyah Purwanti; Widaddhiya Zahra Anggraini; Adelia Royan Suryani; Tolak Haris; Lubis Nuril Ubaidilla
Jurnal Kesehatan dr. Soebandi Vol 12 No 1 (2024): Jurnal Kesehatan dr. Soebandi
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas dr. Soebandi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36858/jkds.v12i1.712

Abstract

Rambusa leaves are known to have health benefits, including anti-inflammatory, antitumor, anticancer, antihepatotoxicity and antimicrobial. Rambusa leaves contain active compounds including alkaloids, tannins, saponins, and steroids which have anti-inflammatory effects. So it was developed as a transdermal route preparation in the form of a patch to overcome the problem of side effects from using oral medications on the gastrointestinal tract. Rambusa leaves are formulated into additional ingredients in the form of HPMC, methyl paraben, propylene glycol, 96% ethanol, distilled water and made into ready-to-use patches. Furthermore, an evaluation of the physical quality of the formula was carried out and its anti-inflammatory effectiveness was determined through in vitro and in vivo tests. The results show that each formula produces physical properties that meet the requirements. Apart from that, the results of the in vitro test using sodium diclofenac as a standard show that formulas 100, 200 and 300 are able to penetrate the membrane from the results of the cumulative amount of active ingredients that have been tested, whereas in the in vivo test using wistar rat test, the results of % edema were analyzed using ANOVA and the results of % inhibition were carried out in a post hoc test with LSD. The highest effectiveness was obtained in formula 300, this shows that the formula is capable of inhibiting inflammation. From these results it can be concluded that rambusa leave extract can be developed into a transdermal patch formula for anti-inflammation.
Total Alkaloid Determination in Ethanolic Extract of Cocoa (T. cacao) and Robusta Coffee (C. canephora) Beans using TLC-Densitometric Method Setyaningrum, Lindawati; Purwanti, Aliyah; Jannah, Roudatul; Diana, Nadha Nofa; Wardani, Astrid Kusuma; Armandari, Inna
Indonesian Journal of Chemical Analysis (IJCA) Vol. 9 No. 1 (2026): Indonesian Journal of Chemical Analysis
Publisher : Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/ijca.vol9.iss1.art1

Abstract

Alkaloids are a major class of bioactive secondary metabolites commonly found in various natural products, including cocoa (Theobroma cacaoL.) and robusta coffee (Coffea canephora). These compounds have been widely reported to exhibit important pharmacological activities, including antioxidant, antidiabetic, antifungal, and antibacterial effects, making them valuable candidates for the development of pharmaceutical and functional herbal products. This study aimed to provide reliable quantitative data on the total alkaloid content of ethanolic extracts from cocoa (Theobroma cacao L.) and robusta coffee (Coffea canephora) beans using the TLC-densitometric method, thereby supporting the standardization, quality control, and potential pharmaceutical applications of these natural materials. However, alkaloid was extracted and fractioned from cocoa and robusta coffee beans using ethanol and chloroform. The total alkaloids in the ethanolic extracts of cocoa and robusta coffee beans were identified by TLC-Densitometry, with average Retardation factors (Rf) of 0.321 and 0.771, respectively. Caffeine was used as a standard. The quantification of total alkaloid in the ethanolic extract of cocoa and robusta coffee beans was 2.003% per 50 mg and 11.713% w/w per 10 mg extract, respectively. In summary, cocoa and robusta coffee beans show promising potential as herbal medicines because they contain substantial levels of pharmacologically active alkaloid compounds.
Identification of Function Groups of Ethanol Extract and n-Hexane Extract of Coriander Seeds (Coriandrum sativum) Using Infrared Spectrophotometer Dhina Ayu Susanti; Lindawati Setyaningrum
Health Media Vol. 1 No. 2 (2020)
Publisher : UrbanGreen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55756/hm.v1i2.32

Abstract

Coriander (Coriandrum sativum) is a popular spice plant in Indonesia. Some active compounds contained in coriander seeds can be used as natural analgesics. This study aims to identify the functional groups contained in coriander seed extract. The solvent used to make coriander seed extract is ethanol and n-hexane, while the extraction method uses sohxlet. The extract obtained was then identified by its functional group using an Infrared spectrophotometer. The results of the identification of functional groups in the ethanol extract of coriander seeds showed some uptake that appeared at a wavelength of 3371.29 cm-1; 2923.59 cm-1; 2853.95 cm-1; 1583.22 cm-1; 1400.71 cm-1, and 1074.80 cm-1. The results of the identification of functional groups in the n-Hexane extract of coriander seeds showed some uptake that appeared at wavelengths of 2923.32 cm-1; 2853.41 cm-1; 1745.36 cm-1; 1461.9 cm-1; 1376.54 cm-1, 1161.67 cm-1, and 919.32 cm-1.
Improving the Knowledge and Skills of Posyandu Mothers Through Nutraceutical Training for Stunting Prevention in Darsono Village Dewi Rashati; Asa Falahi; Anies Rohman D; Lindawati Setyaningrum; Dyan Wigati
Nanggroe: Jurnal Pengabdian Cendikia Vol 5, No 2 (2026): May 2026
Publisher : Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.20438224

Abstract

Stunting remains a major nutritional problem that requires community-based preventive strategies. This community service program aimed to improve the knowledge and practical skills of Posyandu mothers regarding stunting prevention through nutraceutical training in Darsono Village. The program involved 30 participants using a one-group pretest–posttest approach. Activities consisted of educational sessions on stunting, critical prevention periods, nutraceutical concepts, and the benefits of turmeric, followed by practical training in preparing turmeric pudding as a functional food product. Knowledge changes were assessed using pretest and posttest questionnaires. The results showed improved participant knowledge across all measured indicators after the intervention. The greatest improvement was found in understanding nutraceutical concepts (33.33%), followed by knowledge of nutraceutical dosage forms (26.66%) and the benefits of nutraceuticals (26.66%). The training also strengthened participants’ practical ability to utilize local food resources as an innovative nutritional intervention. These findings suggest that combining health education with hands-on practice is an effective strategy to strengthen community capacity in stunting prevention.
Improving the Knowledge and Skills of Posyandu Mothers Through Nutraceutical Training for Stunting Prevention in Darsono Village Dewi Rashati; Asa Falahi; Anies Rohman D; Lindawati Setyaningrum; Dyan Wigati
Nanggroe: Jurnal Pengabdian Cendikia Vol 5, No 2 (2026): May 2026
Publisher : Yayasan Daarul Huda Kruengmane

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5281/zenodo.20438224

Abstract

Stunting remains a major nutritional problem that requires community-based preventive strategies. This community service program aimed to improve the knowledge and practical skills of Posyandu mothers regarding stunting prevention through nutraceutical training in Darsono Village. The program involved 30 participants using a one-group pretest–posttest approach. Activities consisted of educational sessions on stunting, critical prevention periods, nutraceutical concepts, and the benefits of turmeric, followed by practical training in preparing turmeric pudding as a functional food product. Knowledge changes were assessed using pretest and posttest questionnaires. The results showed improved participant knowledge across all measured indicators after the intervention. The greatest improvement was found in understanding nutraceutical concepts (33.33%), followed by knowledge of nutraceutical dosage forms (26.66%) and the benefits of nutraceuticals (26.66%). The training also strengthened participants’ practical ability to utilize local food resources as an innovative nutritional intervention. These findings suggest that combining health education with hands-on practice is an effective strategy to strengthen community capacity in stunting prevention.
Optimization and Validation of Caffeine in Robusta Coffee (Coffea canephora), Black Tea (Camellia sinensis), and Cocoa (Theobroma cacao L.) Using RP-HPLC Liquid-liquid Extraction Lindawati Setyaningrum; Aliyah Purwanti; Dina Trianggaluh Fauziah; Retno Eka Lestari; Dyah Purwaningtyas; Sindi Anggraiyani; Muhammad Yuwono
Journal of Pharmaceutical Sciences and Community Vol. 23 No. 1 (2026)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.v23i1.1086

Abstract

Caffeine, an alkaloid compound naturally found in various consumer products, has become the focus of increasing research in the analysis of products such as black tea, cocoa, and coffee. The chemicals found in coffee, cocoa, and black tea have pharmacological actions including antiviral, antihypertensive, antidiabetic, antioxidant, and hepatoprotective effects against hepatitis B. The chemical components include caffeine, theobromine, theophylline, tannins, adenine, vitamins (including vitamin C), flavonoids, methylxanthine, naringenin, and polyphenols. The resultant viscous extract was mixed with 25 milliliters of chloroform and 1.5 grams of CaCO3 in a separatory funnel and stirred. Three times, chloroform solution was added. The HPLC analytical method requires a wavelength of 272 nm, a methanol: redistilled water (70:30) mobile phase, and a flow rate of 1.0 mL/min to be validated. Results show resolutions of 1.49 and 1.57 for selectivity values, linearity of r = 0.9994, LOD 8.511 ppm and LOQ 28.370 ppm, accuracy of 99–101% for average recovery value, and precision of %The RSD level is 0.0095%. The results of the caffeine content determination test showed that the ethanol extract of robusta coffee beans obtained from the caffeine content ± SD obtained was 9.682 ± 1.254, black tea 34.525 ± 0.064, and cacao 6.890 ± 0.488.
EDUKASI PROTOKOL KESEHATAN DAN PEMBUATAN HAND SANITIZER DALAM RANGKA PERSIAPAN SEKOLAH TATAP MUKA dyan wigati; Lindawati Setyaningrum; Iski Weni Pebrianti; Edi Susanto; Dwi Koko Pratoko
JURNAL ABDI MERCUSUAR Vol 1 No 1 (2021): Jurnal ABDI MERCUSUAR
Publisher : LPPM Universitas MERCUBAKTIJAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36984/jam.v1i1.198

Abstract

Pandemi Coronavirus Disease-2019 (COVID-19) saat ini masih berlangsung dan masih belum ada kejelasan kapan usai. Beberapa hal yang sudah dilakukan sebagai upaya pemutusan rantai penyebaran virus diantaranya penerapan protokol kesehatan, pembatasan berkegiatan dan pemberian vaksin. Dalam hal persiapan kegiatan sekolah tatap muka, diperlukan beberapa hal diantaranya sarana dan kesiapan setiap personel di sekolah baik pendidik maupun siswa siswinya. Untuk menunjang hal tersebut maka dilakukan pengabdian masyarakat dengan fokus edukasi tentang protokol kesehatan dan pelatihan pembuatan handsanitizer bagi pendidik dan tenaga kepedidikan yang nantinya berinteraksi langsung dengan siswa siswi di sekolah.
Formulasi dan Evaluasi Sediaan Krim Perona Pipi dari Ekstrak Bunga Rosela (Hibiscuss sabdariffa L.) sebagai Pewarna Alami Ajeng Retno Ningsih; Dina Trianggaluh Fauziah; Lindawati Setyaningrum; Jenie Palupi
Journal of Pharmacy and Halal Studies Vol. 3 No. 1 (2025): Journal of Pharmacy and Halal Studies (JPHS)
Publisher : Edu Science Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70608/gzbqnr42

Abstract

Perona pipi ialah sediaan kosmetik yang digunakan untuk memberikan warna pada pipi dengan pilihan warna yang beragam. Bahan alami yang digunakan sebagai pewarna alami adalah bunga rosela (Hibiscus sabdariffa L.). Tujuan daripada penelitian ini guna mengidentifikasi senyawa antosianin pada penggunaan ekstrak bunga rosela (Hibiscus sabdariffa L.) kosentrasi 5%, 10%, dan 15% pada krim perona pipi. Serta mengidentifikasi uji evaluasi krim perona pipi melalui uji organoleptik, pH, homogenitas, daya sebar, daya lekat, iritasi, serta hedonik. Penelitian ini menerapkan metode eksperimental laboratorium dengan melakukan skrining antosianin, dan melakukan uji evaluasi berupa uji organoleptik, pH, homogenitas, daya sebar, daya lekat, iritasi serta hedonik. Hasil dari penelitian ini yaitu ekstrak bunga rosela positif mengandung senyawa antosianin. Hasil evaluasi uji organoleptik krim perona pipi kosentrasi ekstrak 5%, 10 % dan 15% memiliki tekstur semi padat dengan aroma khas bunga rosela dan memiliki warna pada kosentrasi 5% putih sedikit pink, 10% pink muda, 15% pink gelap. pH krim perona pipi kosentrasi ekstrak 5% yaitu 6.73, 10%  6.53, 15% 5.63. Uji homogenitas krim perona pipi kosentrasi ekstrak 5%, 10%, dan 15% yaitu homogen. Uji daya sebar krim perona pipi  kosentrasi ekstrak 5% yaitu 5.3 cm, 10% 6.3 cm dan 15% 5.7 cm. Uji daya lekat krim perona pipi kosentrasi ekstrak 5% yaitu 7.07 detik, 10% 6.53 detik. dan 15% 6.77 detik. Uji iritasi krim perona pipi kosentrasi ekstrak 5%, 10% dan 15% yaitu tidak menimbulkan iritasi. Uji hedonik krim perona pipi kosentrasi ekstrak 15% banyak disukai responden dalam segi tekstur, warna dan aroma.
Co-Authors Adelia Royan Suryani Adelia Royan Suryani Aditya F. Ardinsyah Ajeng Retno Ningsih Aliyah Purwanti Aliyah Purwanti Aliyah Purwanti Aliyah Purwanti Alwiya Kinanti Amalia Wardatul Firdaus Anies Rohman D Anies Rohman Dwijayanti Anies Rohman Dwijayanti Aninda Fellisya Wibowo Aninda Fellysia Wibowo Asa Falahi Asa Falahi Asa Falahi Asti Rahayu Astrid Kusuma Putri Ayik Rosita Puspaningtyas1 Ayu Dwi Wardani Canakya Niti Sastra Deva Oktavy American Iswardjono Dewi Rashati Dhina Ayu Susanti Dhina Ayu Susanti Diah Yuli Pangesti Dian Reny Agustina Diana, Ilvid Diana, Nadha Nofa Dina Trianggaluh Fauziah Dina Trianggaluh Fauziah Dina Trianggaluh Fauziah Dwi Koko Pratoko Dyah Purwaningtyas Dyah Purwaningtyas Dyan Wigati Edi Susanto Eka Fitri Yanti, Eka Fitri Falakh Noferyana Hartania Wati Fenti Indah Nirwana Iftinan Syifa Dzulfiqar Ima F. Lestari Inna Armandari Iski Weni Pebrianti Iski Weni Pebriarti Iski Weni Pebriarti Ivana, Nanda Letitia Jenie Palupi Khrisna Agung Cendekiawan Lubis Nuril Ubaidilla Lubis Nuril Ubaidilla Lulut Sasmito Lunardhi Susanto M. Rofik Usman Maasyitoh Sari Latifah Mega T. Wulandari Mohamad Rofiq Usman Mohammad R. Usman Mohammad Rofik Usman Mohammad Rofik Usman Muhamad D. Permana Muhammad Yuwono Nabila Kamalia Nafisah Isnawati Neny Poerwahyuningrum Nur Azizah Perdani Puteri Syahuri Purwanti, Aliyah Qurrotul Aini Retno Eka Lestari Rizki Indah Rahayu ROUDATUL JANNAH Septyaningtyas Eka Wulandari Shinta Mayasari Sholihatil Hidayati Sholihatil Hidayati Sindi Anggraiyani Stephanie D. Artemisia Tiara Anjelina Hezni Tolak Haris Tolak Haris Tsalisah Rahmaniyyah Arifin Ulfa Dwi Septiana Wardani, Astrid Kusuma Widaddhiya Zahra Anggraini Widaddhiya Zahra Anggraini Wima Anggitasari Wima Anggitasari Winda Sastika