Riki Tenggara
Department Of Internal Medicine, Faculty Of Medicine, Atma Jaya Catholic University Of Indonesia, Jakarta

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Association Between Coffee Consumption and Gastroesophageal Reflux Disease (GERD): A Cross-Sectional Analysis Hartoyo, Farrell ZR; Tandarto, Kevin; Sidharta, Veronika; Tenggara, Riki
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 23, No 1 (2022): VOLUME 23, NUMBER 1, April 2022
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (451.43 KB) | DOI: 10.24871/231202211-16

Abstract

Background: Gastroesophageal reflux disease (GERD) is a condition in which stomach contents flow back into the esophagus, leading to various symptoms and complications. In Indonesia, the prevalence of GERD has been reported at 57.6%. Coffee consumption is often suspected to be closely linked to the occurrence of GERD. This study aims to determine the association between coffee consumption and the incidence of GERD.Methods: This study used a cross-sectional approach to conduct observational analytical research. The sample included individuals aged 18 to 65 years residing in Jakarta, selected using a consecutive sampling method. Data were collected using the Indonesian version of the Gastroesophageal Reflux Disease Questionnaire (GERD-Q). To assess the association between coffee consumption and GERD, the Chi-square test of independence was applied.Results: Out of 105 respondents, 26 were identified as having GERD. Among those, 84.6% reported consuming coffee at moderate to high frequencies, while 15.3% consumed little to no coffee. The Chi-square test of independence revealed a statistically significant association between coffee consumption and GERD among Jakarta residents aged 18 to 65 years (p = 0.006).Conclusion: There is a significant association between coffee consumption and the incidence of gastroesophageal reflux disease (GERD) among Jakarta residents aged 18 to 65 years.
The Potential of Alpha-Lipoic Acid Supplementation for Non-Alcoholic Fatty Liver Disease: A Systematic Review Prasetya, Alver; Tobian, Nikolaus; Tanjaya, Hendri; Tenggara, Riki; Loe, Luse
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 26, No 3 (2025): VOLUME 26, NUMBER 3, December, 2025
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/2632025204-211

Abstract

Background: Insulin resistance, genetic susceptibility, oxidative stress, and inflammation lead to the development of non-alcoholic fatty liver disease (NAFLD). Alpha lipoic acid (ALA) has demonstrated benefits in enhancing insulin sensitivity and reducing inflammatory reactions in both human and animal studies. This study aims to determine the effectiveness of ALA against NAFLD.Methods: Detailed searches were conducted across several databases, including PubMed, CENTRAL, Europe PMC (medRxiv and bioRxiv), EBSCOhost (Medline), and ProQuest, using keywords such as lipoic acid, metabolic-associated fatty liver disease, steatohepatitis, and non-alcoholic fatty liver disease. Risk of bias was assessed using the Cochrane risk-of-bias tool for randomized trials.Result: Four studies were included in which the ALA effect was compared with placebo or no intervention. A significant reduction in BMI (p0.001), lipid profiles (p0.05), glycemic markers (p0.05), liver enzymes (p0.05), oxidative stress (p0.05), and fibrosis score (p0.05) was seen in NAFLD patients with ALA supplementation.Conclusion: This study shows that ALA may help manage NAFLD. However, further research is required to establish robust evidence.
Deteksi Antigen Helicobacter pylori Pada Pasien GERD dan Non-GERD di Rumah Sakit Atma Jaya Athalia Nofera Kurniawan; Riki Tenggara; Lucky Hartati Moehario
Majalah Kedokteran Indonesia Vol 69 No 8 (2019): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.69.8-2019-185

Abstract

Introduction: Helicobacter pylori (H. Pylori) is one of normal human microbiota live in human stomach and often associated with dyspepsia, however, its association with Gastroesophageal Reflux Disease (GERD) is still controversial. The diagnosis of H. pylori is often established through histopathological examination, an invasive urease tests, and urea breath test (UBT. Serological tests are also used to diagnose H. pylori, one of which is Stool Antigen Test (SAT), which is cheaper, non-invasive and easier to operate. The purpose of this study was to detect H. pylori antigen in GERD and non-GERD patients at Atma Jaya Hospital.Method: This study was a descriptive cross-sectional. Participants in this study were adult patients hospitalised in Atma Jaya Hospital from August 2018 - November 2018, interviewed with GERDQ questionnaire and stool samples were collected. Stool Antigen Test was carried out using SAT from Biocare®. Results: Thirty participants were included in this study, consisted of 22 women and 8 men, and predominated by adult age group (35–64 years old). Forty percent participants were GERD group consisted of 75% women. Positive SAT test results in the GERD group was 16.67%, non-GERD was 11.11%, and negative SAT test results in the GERD group was 91.67%, non-GERD was 77.78%. Conclusion: The presence of H. pylori antigen was detected in women in the adult age group. It seemed the presence of H. pylori was not different from GERD group and non-GERD group.