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All Journal BALI MEDICAL JOURNAL (BMJ) SOEPRA Jurnal Hukum Kesehatan Medica Hospitalia Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Jurnal Health Sains Diponegoro International Medical Journal (DIMJ) Madani: Multidisciplinary Scientific Journal Neurona Seroja Husada: Jurnal Kesehatan Masyarakat
Dodik Tugasworo
Department of Neurology Faculty of Medicine, University of Diponegoro
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Effect Of Triamcinolone Trigger Point Injection On Changes In TNF-α Levels And Oswestry Disability Index (ODI) Scores Non-Specific Low Back Pain (LBP) Patients Fakih, Mohamad; Suryadi; Tugasworo, Dodik; Pudjanarko, Dwi; Husni, Amin; Budisulistyo, Trianggoro; Puspitawati, Arinta
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 1 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i1.976

Abstract

Background: Low back pain (LBP) is the most common musculoskeletal problem and a major cause of worldwide disability causing increased health costs and indirect costs associated with reduced or lost productivity. One of the therapeutic management of LBP is Triamcinolone trigger point injection. Until now, research on the effect of Triamcinolone trigger point injection on changes in TNF-α levels and Oswestry Disability Index (ODI) scores in Non-Specific LBP patients is still limited. Objective: To analyze the effect of Triamcinolone trigger point injection on changes in TNF-α levels and ODI scores before and after Triamcinolone trigger point injection in Non-Specific LBP patients. Methods: This is a quasi-experimental analytic observational study with a pre and post-test group design approach. Subjects were diagnosed with Non-Specific LBP who had met the inclusion criteria (acute pain less than 3 months, patient age 30-55 years, moderate-severe pain intensity, had never received a Triamcinolone trigger point injection) with the exclusion criteria patients experiencing severe pain. not only caused by NPB. The study subjects were checked for TNF-α levels and ODI scores before and after the Triamcinolone trigger point injection. Then a paired T-test was carried out. Results: During the study period September - November 2022 at the Neurology Outpatient Polyclinic, RSUP Dr. Kariadi Semarang obtained 32 subjects. There was a significant difference between changes in TNF-α levels before and after Triamcinolone trigger point injection (p=0.000). There was a significant difference in ODI scores before and after the Triamcinolone trigger point injection (p=0.000). There was no significant relationship between the risk factors for gender, occupation, BMI, physiotherapy, and changes in TNF-α levels with changes in the ODI score. Conclusion: There is a significant difference in changes in TNF-α levels and ODI scores before and after Triamcinolone trigger point injection.
Prenatal, Perinatal And Postnatal Risk Factors From Mother And Child To The Incidence Of Epilepsy Sibuea, Susan Megawati; Kustiowati, Endang; Samekto, Maria Immaculata Widiastuti; Tugasworo, Dodik; Bintoro, Aris Catur; Pasmanasari, Elta Diah
Medica Hospitalia : Journal of Clinical Medicine Vol. 11 No. 1 (2024): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v11i1.1042

Abstract

BACKGROUND: Epilepsy is a health problem that affects sufferers and their families, characterized by at least two seizures without provocation with an interval of more than 24 hours between seizures, one seizure without provocation with the possibility of recurring within 10 years, a diagnosis of epilepsy syndrome has been established. The risk of epilepsy can be influenced by the condition of the mother and child in the prenatal, perinatal and postnatal periods. AIMS: This study analyzed the risks of several prenatal, perinatal, and postnatal factors of mother and child as risk factors for epilepsy incidence. METHOD: A case control study was conducted at RSUP Dr. Kariadi Semarang from July 2022 to March 2023. A total of 90 eligible subjects  were divided into 45 case with epilepsy and 45 control with a non-epileptic diagnosis. Inclusion criteria were aged over 17 years to 40 years and exclusion criteria were subjects with mothers who had died or could not be interviewed, data were incomplete and had structural brain disorders or other diseases with clinical symptoms of seizures for the control group. The data obtained were analyzed  using chi squares test for bivariate association, followed by multivariate analysis with multiple logistic regression. RESULT: Maternal age during pregnancy (p=0.016), low birth weight (p=0.007), surgical birth (p=0.004), head trauma at the age of less than 6 years (p=0.008) have been shown to influence the occurrence of epilepsy with significance respectively. CONCLUSION: Prenatal factors of the mother which is maternal age during pregnancy, perinatal and postnatal factors of the child which are low birth weight, surgical birth, and head trauma at the age of less than 6 years are risk factors that influence the occurrence of adulthood epilepsy.
Pelindungan Hak atas Rahasia Medis Pasien dalam Implementasi Rekam Medis Elektronik (Studi pada Rumah Sakit Bhayangkara, Semarang) Wahyuntara, Jaka Kusnanta; Yustina, Endang Wahyati; Tugasworo, Dodik
Soepra Jurnal Hukum Kesehatan Vol 10, No 1: Juni 2024
Publisher : Universitas Katolik Soegijapranata Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24167/sjhk.v10i1.11498

Abstract

Peraturan Menteri Kesehatan Nomor 24 tahun 2022 tentang Rekam Medis mengharuskan seluruh fasilitas penyelenggara pelayanan Kesehatan menggunakan Rekam Medis elektronik. Rekam Medis elektronik harus memenuhi prinsip keamanan data dan informasi, meliputi: kerahasiaan; integritas; dan ketersediaan. Rumah Sakit Bhayangkara Semarang memiliki kompartemen Dokpol yang tidak dimiliki oleh rumah sakit umum. Pasien yang berkunjung meliputi  anggota POLRI dan keluarga , ASN dan keluarga, pasien umum, serta pasien tahanan, baik tahanan tindak pidana umum, tindak pidana khusus, bahkan tindak pidana terorisme. Sehingga dalam perlindungan hak  atas rahasia medis pasien membutuhkan implementasoi Peraturan Menteri Kesehatan Nomor 24 tahun 2022 tentang Rekam Medis yang agak berbeda.Penelitian ini menggunakan metoda penelitian normatif-empiris dengan spesifikasi penelitian deskriptif analitis, dengan desain penelitian kualitatif. Jenis data berupa bahan hukum primer, sekunder dan tersier. Metode pengumpulan datanya meliputi studi kepustakaan, observasi, dan wawancara. Data dianalisa dengan Analisa kualitatif.Hasil penelitian dan Diskusi : Pengaturan Perlindungannya dilaksanakan sesuai dengan Peraturan Perundang-undangan yang berlaku, meliputi bentuk pengaturan umum dan pengaturan khusus dan dengan tujuan pengaturannya sebagaimana yang tertuang dalam Peraturan Menteri Kesehatan Nomor 24 Tahun 2022 Tentang Rekam Medis ; Implementasinya  dilaksanakan oleh subyek-subyek yang terkait, dengan bentuk Implementasi                    Standar Manajemen Informasi, Standar, Pengelolaan Dokumen, dan Standar Rekam Medis Pasien, dengan mekanisme meliputi; penyelenggaraan, kegiatan, kepemilikan dan isi, keamanan dan perlindungan data: kerahasiaan; pembukaan isi, pelepasan hak atas Isi, serta    jangka waktu penyimpanan; Faktor-faktor yang Mempengaruhi Implementasi meliputi faktor yuridis, faktor sosial, dan faktor teknis.Implementasi perlindungan terhadap hak atas rahasia medis pasien di Rumah Sakit Bhayangkara Semarang telah berjalan cukup efektif dan efisien, walaupun tidak sedikit permasalahan yang timbul. Masalah pemahaman substansi Peraturan Menteri Kesehatan tentang Rekam Medis, kualitas kesadaran simpan rahasia medis yang belum begitu menggembirakan, dan terbatasnya kuantitas SDM yang mumpuni , serta hardware maupun soft ware yang tidak sedikit yang perlu dipersiapkan oleh rumah sakit menjadi tantangan tersendiri di dalam implementasi peraturan ini
CORRELATION OF TNF-ALFA INFLAMMATION BIOMARKER LEVELS WITH THE INDONESIAN VERSION OF MONTREAL COGNITIVE ASSESSMENT (MOCA-INA) SCORES IN LAKUNAR ISCHEMIC STROKE PATIENTS Hamdani, Faishol; Hartono, Jimmy Eko Budi; Tugasworo, Dodik; Retnaningsih, Retnaningsih; Suryawati, Herlina; Puspitawati, Arinta
Seroja Husada: Jurnal Kesehatan Masyarakat Vol. 1 No. 5 (2024): Seroja Husada: Jurnal Kesehatan Masyarakat
Publisher : Seroja Husada: Jurnal Kesehatan Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Background: Tumor Necrosis Factor-Alpha (TNF-α) is a pro-inflammatory cytokine that is responsible for modulation the immune system. TNF-α is another important mediator involved in stroke pathophysiology. Cerebral small vessel disease (CSVD) is a major cause of lacunar ischemic stroke. In stroke there is an increase in TNF-α levels where post-stroke neuroanatomic damage can cause cognitive impairment. Objective: Proving the relationship between TNF-α serum levels on the day 3 of onset and the Moca Ina score on the day 7 of onset, day 30, and the difference in MoCa-INA scores and analyzing the relationship of risk factors cognitive function in lacunar ischemic stroke patients. Methods: An analytical observational study with a prospective cohort approach. Subjects were first-time lacunar ischemic stroke with blood sampling on the day 3 of onset to evaluate TNF-α levels. Cognitive function was examined by the MoCa-INA score which was evaluated on day 7 and day 30. Eta correlation test to connect TNF-α levels with MoCa-INA scores. Bivariate and multivariate analyzes used between the MoCa-INA score and other confounding factors. Results: There was a strong correlation between TNF-α levels on day 3 of onset and MoCA-INA on day 7 (ƞ= 0.972), a very strong correlation was found between TNF-α levels on day 3 of onset and MoCA-INA on day 30 (ƞ= 1,000), and there was a strong correlation between TNF-α levels on day 3 of onset and the difference between MoCA-INA (ƞ=0.905). there is a confounding variable diabetes mellitus that affects the 7th day of MoCA-INA. In the sub-analysis study, the mean serum TNF-α level on cognitive impairment on day 30 was higher than on day 7 with the most dominant domains being visuospatial and executive. Conclusion: There is a strong relationship between serum TNF-α levels and MoCa-INA scores in lacunar ischemic stroke patients, and there is one confounding variable of diabetes mellitus that affects the MoCa-INA score on the 7th day of examination.
Optimizing Brain-Computer Interfaces for Methampetamine Use Disorder through Quantitative Electroencephalography (QEEG) and Transcranial Doppler Analysis: Article Review Caroline, Maria; Syahrul, Syahrul; Tugasworo, Dodik; Retnaningsih, Retnaningsih; Juswanto, Gerard
Jurnal Health Sains Vol. 5 No. 9 (2024): Journal Health Sains
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jhs.v5i9.1372

Abstract

A Brain-Computer Interface (BCI) is a system that allows a person to control external devices using only their brain activity. It works by translating brain signals into commands that can be understood by a computer. Several lines of evidence demonstrated the deleterious effect of methamphetamine (MA) on neurological and psychological functions. The use of amphetamines, such as MA, is associated with cerebrovascular complications such as cerebrovascular accidents (CVA) ,hemorrhage, hypoxic damage and vasculitis. Interestingly, while changes to cerebral blood flow (CBF) in response to acute amphetamine exposure have been reported. Transcranial Color Doppler (TCCD) is a non-invasive medical imaging technique that uses ultrasound waves to measure blood flow velocity in the major arteries of the brain, specifically within the circle of Willis. The research paper you referenced explores the use of TCCD as a potential measurement modality for BCIs. Quantitative electroencephalogram (qEEG) is a powerful tool for understanding brain function qEEG can reveal specific brain wave patterns associated with drug addiction, potentially providing insights into the neurobiological mechanisms underlying cravings, withdrawal symptoms, and relapse risk in Methamphetamine User Disorder (MUD). There is growing research interest in using Transcranial dopller as a measurement modality for BCIs.Here are some of the key considerations for using Transcranial doppler in BCIs: Mental Tasks, signal processing and classification, accuracy and reliability. Transcranial doppler provides information about blood flow in specific arteries but lacks detailed spatial information about brain activity. These patterns could vary depending on the type of drug, the severity of addiction, and individual differences. Transcranial doppler in measuring middle cerebral artery (MCA) blood flow velocity parameters (peak systolic velocity (PSV) and mean flow velocity (MFV)). qEEG can help researchers investigate the complex interplay between addiction and other brain disorders, like depression or anxiety. Characteristic qEEG in drugs addiction Increased Theta (4-8 Hz) and delta (1-4 Hz) brain waves are often associated with sleep and relaxation. However, research has shown that individuals with drug addiction may have increased theta and delta activity, particularly in the frontal and temporal regions of the brain. Altered Beta (13-30 Hz) brain waves are generally associated with wakefulness, alertness, and cognitive processing. Studies have observed both increases and decreases in beta activity in individuals with drug addiction, depending on the type of drug, the stage of addiction, and the specific brain regions being examined. The results of this research have important practical implications for building an diagnostic and functional assement with a better understanding of an using technology.
The Relationship Between Severity of Periodontitis With the Degree of Atherosclerosis in Ischemic Stroke Patients Tikalaka, Elisabeth Romana; Husni, Amin; -, Retnaningsih; Tugasworo, Dodik; Hartono, Jimmy Eko Budi; Rahmawati, Maria Belladonna; Puspitasari, Iva
Diponegoro International Medical Journal Vol 2, No 2 (2021): December
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v2i2.9605

Abstract

AbstractBackground : Periodontal diseases affect up to 80% of the global population. Periodontitis is a long-term inflammatory disease that affects the soft and hard tissues around the teeth. It may also play a role in the pathogenesis of atheroma formation and is associated with cerebrovascular disease. The Carotid Intima Media Thickness (CIMT) is a good marker for detecting early and progressive atherosclerosis. Several hypotheses link chronic infectious diseases, including periodontal tissue disease, to the atherosclerosis process and are risk factors for stroke.Objective : To determine the relationship between the severity of periodontitis and the degree of atherosclerosis in ischemic stroke.Methods : This is an analytic observational study with a case-control approach. Subjects were ischemic stroke patients with inclusion criteria. Analyzed the severity of periodontitis with Miller’s Mobility Index (MMI), the degree of progression of atherosclerosis assessed by measuring the CIMT using an ultrasound device or B mode to detect the presence and progression of atherosclerosis.Results : 54 subjects with a mean age were 63,43 ± 7,19 years, and the dominant sex was male. There was a significant relationship between severity of periodontitis  ( P : 0,011, OR : 3,425, CI 95% 1,332-8,807) and type of profile lipid triglyceride ( P : 0,027, OR : 6,840, CI 95% 1,242-37,676)  to Carotid intima media thickness.Conclusion :  There is an association between the severity of periodontitis and the degree of atherosclerosis. Severe periodontitis is related to the increases of CIMT, which is a marker of atherosclerosis, a risk factor for stroke.
ANALISIS KORELASI SKOR GEJALA TOTAL, NYERI, DAN KUALITAS HIDUP SETELAH PENGOBATAN VITAMIN B1, B6, DAN B12 DOSIS TINGGI PADA NEUROPATI PERIFER Hakim, Manfaluthy; Kurniani, Nani; Pinzon, Rizaldy; Tugasworo, Dodik; Basuki, Mudjiani; Haddani, Hasnawi; Pambudi, Pagan; Fithrie, Aida; Wuysang, Audry Devisanty
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 35 No 2 (2018)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v35i2.3

Abstract

CORRELATION ANALYSIS OF TOTAL SYMPTOM SCORE, PAIN, AND QUALITY OF LIFE POST HIGH DOSE VITAMIN B1, B6, DAN B12 TREATMENT IN PERIPHERAL NEUROPATHYABSTRACTIntroduction: Peripheral neuropathy (PN) is a clinical condition in which nerves of the peripheral nervous system are damaged and is associated with various symptoms affecting the patients’ quality of life (QoL).Aims: To understand the  effect of Vitamin B1, B6, and B12 combination in mild to moderate PN.Methods: This is a prospective, open label, multicenter, single arm observational study involved 399 subjects with PN of different etiology. Subjects received the vitamin B1, B6, and B12 combination tablet orally once daily and were observed for 3 months. Total symptom score (TSS), visual analog score (VAS) and QoL were assessed, and the correlation between these parameters was analyzed.Results: Clinically significant reductions were observed from baseline to subsequent visits for TSS and VAS. Positive correlation  was observed between TSS and components of VAS. The study treatment was associated with a significant improvement in QoL parameters. Inverse correlation was observed between QoL and TSS as well as QoL and components of VAS. The study treatment was found to be well tolerated.Discussion: The correlation  analysis between different outcome measures demonstrated the beneficial effect of combination of vitamin B1, B6, and B12 in relief from symptoms and improvement in QoL of PN.Keyword: Correlation analysis, peripheral neuropathy, SF-8, TSS, VAS, vitamin B1, B6, and B12ABSTRAKPendahuluan: Neuropati perifer (NP) merupakan kondisi klinis akibat kerusakan pada sistem saraf tepi yang memengaruhi kualitas hidup (quality of life/QoL) pasien.Tujuan: Mengetahui efek pemberian kombinasi vitamin B1, B6, and B12 pada NP ringan hingga sedang.Metode: Penelitian observasional dan prospektif secara open label, multisenter, dan single arm, yang melibatkan 399 subjek penderita neuropati perifer dengan etiologi yang berbeda-beda. Subjek mengonsumsi tablet kombinasi vitamin B1, B6, and B12 secara oral satu kali sehari dan diamati selama 3 bulan. Dilakukan penilaian skor gejala total (total symptom score/TSS), visual analog scale (VAS), dan QoL, serta korelasi antara parameter-parameter tersebut.Hasil: Terdapat penurunan TSS dan VAS yang bermakna secara klinis antara baseline (awal) dengan kunjungan berikutnya. Terdapat korelasi yang positif antara TSS dengan komponen-komponen VAS. Pemberian perlakuan dalam penelitian berkorelasi secara bermakna dengan perbaikan parameter dalam QoL. Teramati juga adanya hubungan terbalik antara QoL dengan TSS serta QoL dan komponen VAS. Pengobatan pada penelitian ini juga terbukti dapat ditoleransi dengan baik.Diskusi: Analisis korelasi antara berbagai macam metode pengukuran yang berbeda menunjukkan manfaat dari pemberian kombinasi vitamin B1, B6, and B12 dalam mengurangi gejala dan perbaikan QoL pada pasien PN.Kata kunci: Analisis korelasi, neuropati perifer, kualitas hidup, SF-8, TSS, VAS, vitamin B1, B6, and B12
FAKTOR-FAKTOR RISIKO STROKE PADA PENYAKIT GINJAL KRONIK STADIUM V YANG MENJALANI HEMODIALISIS Ariani, Susanti Dwi; Tugasworo, Dodik; Widiastuti Samekto, Maria Imakulata
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 35 No 2 (2018)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v35i2.105

Abstract

RISK FACTORS OF STROKE IN STAGE V CHRONIC KIDNEY DISEASE WHO UNDERWENT HEMODIALYSISABSTRACTIntroduction: Chronic kidney disease (CKD) and end-stage renal disease are associated with a significantly in- creased risk of stroke. Incidence and mortality of stroke in CKD patients is higher rather than among the general popula- tion. Stroke in hemodialysis patients is also associated with high mortality.Aims: To analyze risk factors that have a relationship with the occurrence of stroke in patients with stage V CKD who underwent hemodialysis in Dr. Kariadi Hospital, Semarang.Method: A case control with retrospective cohort study of patients diagnosed with stage V CKD undergoing hemo- dialysis in Dr. Kariadi Hospital, Semarang, from March 2016 to August 2017. Subject was divided into case group, who experienced stroke, and control group, who did not experience stroke. Bivariate analysis was performed with Chi-square test, multivariate analysis with logistic regression test and rasio Odds.Results: There were 140 subjects with stage V CKD, 70 subjects in each groups. In case group, 85.7% experienced ischemic stroke while the rest hemorrhagic stroke. The duration of hemodialysis was related to the incidence of stroke. In multivariate analysis, patients with diabetes mellitus were more likely to have a stroke by 0.14 times compared to patients who did not have diabetes mellitus, and patients who underwent hemodialysis >12 months, were more likely to have a stroke 4.05 times greater than patients who underwent hemodialysis <12 months.Discussion: There is a relationship between diabetes mellitus and duration of hemodialysis with the occurrence of ischemic stroke, in stage V CKD patients who underwent hemodialysis.Keywords: Chronic kidney disease, hemodialysis, strokeABSTRAKPendahuluan: Penyakit ginjal kronik (PGK) dan penyakit ginjal stadium akhir terkait dengan peningkatan risiko yang signifikan dari stroke. Insiden dan mortalitas stroke pada pasien PGK lebih tinggi dibandingkan populasi umum. Stroke pada pasien dialisis juga dihubungkan dengan mortalitas yang tinggi.Tujuan: Untuk menganalisis faktor-faktor risiko yang memengaruhi terjadinya stroke pada pasien dengan PGK stadium V yang menjalani hemodialisis (HD) di RSUP Dr. Kariadi, Semarang.Metode: Penelitian kasus kontrol dengan pendekatan kohort retrospektif terhadap pasien penyakit ginjal kronik stadium V yang menjalani HD di RSUP Dr. Kariadi, Semarang dari bulan Maret 2016 hingga Agustus 2017. Subjek dibagi ke dalam kelompok kasus, yaitu yang mengalami stroke dan kelompok kontrol yang tidak mengalami stroke. Dilakukan analisis bivariat dengan uji Chi-square dan analisis multivariat dengan uji regresi logistik serta rasio Odds.Hasil: Didapatkan 140 subjek dengan PGK stadium V yang masing-masing kelompok terdiri dari 70 orang. Pada kelompok kasus, sebanyak 85,7% adalah stroke iskemik dan sisanya stroke hemoragik. Lama HD berhubungan dengan kejadian stroke. Pada uji multivariat, subjek yang menderita diabetes melitus (DM) berisiko mengalami stroke sebesar 0,14 kali dibandingkan yang tidak DM dan subjek yang menjalani HD >12 bulan berisiko mengalami stroke 4,05 kali lebih besar dibandingkan yang menjalani HD <12 bulan.Diskusi: Terdapat pengaruh faktor risiko DM dan lama hemodialisis terhadap kejadian stroke iskemik pada pasien PGK stadium V yang menjalani HD.Kata kunci: Hemodialisis, penyakit ginjal kronik, stroke
Praktik Psikoterapi Mengenai Pelatihan Keterampilan Terapi Kelompok Perilaku Dialektika di Indonesia: Pengembangan Modul dalam Bahasa Indonesia Wardani, Natalia Dewi; Widiastuti, Maria Immaculata; Sudiyanto, Aris; Hardian, Hardian; Subagio, Hertanto Wahyu; Tugasworo, Dodik; Maharatih, Gusti Ayu; Lukman, Petrin Redayani; Septiawan, Debree; Suprapti, Rini; Susilo, Kezia Natalia Daniast; Atmaja, Diana; Dewi, Amalia Andansari
Majalah Kedokteran Indonesia Vol 73 No 5 (2023): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.73.5-2023-1126

Abstract

Introduction: There is an increasing number of suicides in Indonesia. A high risk of suicide is often associated with borderline personality disorder (BPD). To address this issue, dialectical behavior therapy (DBT) has been specifically designed for patients with frequent suicidal behavior and BPD. This study aims to develop DBT skills modules in Indonesian language for groups therapy and implement in clinical practice.Methods: This research was conducted in three stages. Stage 1 involved preparing the DBT skills module for 13 weeks, including the adding of TIPP (Temperature, Intense exercise, Paced Breathing, Paired Muscle Relaxation) distress tolerance skills and chain analysis. Stage 2 focused on module validation using face validity and content validity assessment conducted by two psychotherapy consultants. Stage 3 involved modules trials, both of whom had completed DBT training, practicing the prepared modules with two groups of 10 patients.Result: The face validity scores from the two experts for the DBT module on BPD in Indonesian was 3.188, indicating a high level of correctness. The content validity results from the two experts for the DBT module on BPD in Indonesian language were 84.06, indicating that almost everything was done correctly. After practicing DBT group skills training, two psychotherapists achieved a very good interrater score of 0.969 (p=0.003; 95% CI 0.746-0.997).Conclusion: Based on the face validity and content validity scores by the two experts, it was concluded that the DBT module for BPD in Indonesian language is suitable for use in clinical services.
Luaran Klinis dan Komplikasi Terapi Endovaskular pada Pasien Stroke Iskemik Akut dengan Trombolisis Intra-Arteri dan Trombektomi Mekanik pada Setting Penanganan Kritis Retnaningsih, Retnaningsih; Tugasworo, Dodik; Kurnianto, Aditya; Tri Rahayu, Fitriani
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 41 No 3 (2025): Vol 41 No 3 (2024): Volume 41, No 3 - Juni 2025
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v41i3.774

Abstract

Introduction: Acute ischemic stroke (AIS) is a major cause of disability and death worldwide. Mechanical thrombectomy (MT) has become the standard endovascular therapy for AIS with large vessel occlusion, though incomplete reperfusion remains a concern. Intra-arterial thrombolysis (IA-T) has emerged as a potential adjunct therapy to enhance reperfusion. Aim: To evaluate clinical outcomes and complication rates between IA-T plus MT compared to MT alone in AIS patients treated in the ICU of Dr. Kariadi Hospital, Semarang. Methods: A total of 38 AIS patients with MCA occlusion who received endovascular reperfusion therapy were divided into two intervention groups: IA-T + TM (n=18) and TM alone (n=20). Outcomes according to Modified Rankin Scale (mRS) score and complication data were compared between groups. Results: Patients in both groups had similar baseline characteristics. A higher percentage of patients in the IA-T + MT group achieved favorable mRS scores (0–2) compared to the MT-only group (72.2% vs 65%), though the difference was not statistically significant (p=0.632). No significant differences in complication rates were found. Discussion: The combination of IA-T and MT showed a trend toward better functional outcomes without significantly increasing complications. This suggests potential benefit in selected cases. Keywords: ischemic stroke, intra-arterial thrombolysis, mechanical thrombectomy
Co-Authors -, Retnaningsih A.A. Ketut Agung Cahyawan W Agung, Locoporta Amin Husni Andhitara, Yovita Andhitara, Yovita Andhitara Andi Kurnia Bintang, Andi Kurnia Ardhini, Rahmi Ariani, Susanti Dwi Aris Catur Bintoro Aris Sudiyanto Arlina, Yani Atmaja, Diana Basuki, Mudjiani Budi Riyanto Wreksoatmodjo, Budi Riyanto Budisulistyo, Trianggoro Caroline, Maria Daynuri Daynuri, Daynuri Dede Gunawan, Dede Dewi, Amalia Andansari Diah Pasmanasari, Elta Donggorables, Sandra Yap Dwi Pudjonarko Endang Kustiowati Endang Wahyati Yustina, Endang Wahyati Fakih, Mohamad Firli Bramantyo, Dion Fithrie, Aida Fritz Sumantri Usman, Fritz Sumantri Gracia, Anne H. Harsono, H. Hakim, Manfaluthy Hamdani, Faishol Hardian Hardian Harianto, Erlangga Pradipta Hartono, Jimmy Eko Budi Hertanto Wahyu Subagio Hidayah, Ujan Taufik Iva Puspitasari, Iva Jethro Budiman, Jethro Jimmy Barus, Jimmy Juswanto, Gerard Juswanto, Gerard Anthonius Kurnianto, Aditya Kurnianto, Aditya Kurnianto Lakusa, Tim Valentino Lukman, Petrin Redayani Maharatih, Gusti Ayu Mohammad Hasan Machfoed Muhammad Hasnawi Haddani Nani Kurniani Natalia Dewi Wardani Pagan Pambudi Pasmanasari, Elta Diah Priambada, Dody Pudjanarko, Dwi Puspitawati, Arinta R, Retnaningsih Rahmawati, Dani Rahmawati, Maria Belladonna Rahmayanti Rahmayanti Retnaningsih Retnaningsih Retnaningsih Rivo Panji Yudha Riza Sulthan, Riza Rizaldy Pinzon Rusdi Lamsudin, Rusdi Saleh, RM Pangeran Samekto, Maria Immaculata Widiastuti Septiawan, Debree Suprapti, Rini Suryadi Suryadi Suryadi Suryawati, Herlina Susan Megawati Sibuea Susilo, Kezia Natalia Daniast syahrul s, syahrul Syahrul Syahrul Tamad, Fatiha Sri Utami Tammase, Jumraini Tikalaka, Elisabeth Romana Tri Rahayu, Fitriani Tsaniadi Prihastomo, Krisna Wahyuntara, Jaka Kusnanta Widiastuti Samekto, Maria Imakulata Widiastuti, Maria Immaculata Wojtila, Maria Caroline Wuysang, Audry Devisanty