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All Journal Pharmaciana: Jurnal Kefarmasian JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Penelitian Kesehatan Suara Forikes Belitung Nursing Journal JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) JSFK (Jurnal Sains Farmasi & Klinis) JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Respirologi Indonesia Jurnal Ilmu Kefarmasian Indonesia Jurnal Riset Kesehatan Poltekkes Depkes Bandung Indonesian Journal of Cancer Eduvest - Journal of Universal Studies Jurnal Farmasi Indonesia Holistik Jurnal Kesehatan Jurnal Info Kesehatan Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Nadia Farhanah Syafhan
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Aerospace Engineering Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Adverse Drug Reactions, Treatment Adherence, and Treatment Outcomes in Drug-Resistant Tuberculosis Patients: A Single-center, Cross-sectional Study Nadia Farhanah Syafhan; Galuh Zhafirah Rahmita; Sri Wulandah Fitriani
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 10, No 2 (2025)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v10i2.87515

Abstract

Drug-Resistant Tuberculosis (DRTB) is a significant global health issue due to its rapid transmission and high morbidity. The variety of medications used in DRTB treatment increases the risk of adverse drug reactions (ADRs), which can contribute to patient nonadherence and adversely affect treatment outcomes. This study aimed to describe the occurrence of ADRs, quantify medication adherence rates, and assess treatment outcomes among patients with drugresistant tuberculosis (DRTB). Furthermore, it sought to analyse the associations between ADRs, demographic and clinical variables, medication adherence, and the associations between ADRs and treatment outcomes. Using a cross-sectional design, this study utilized medical records data and the Tuberculosis Information System (SITB) of adult DRTB patients treated at Universitas Indonesia Hospital from April 1, 2022, to February 28, 2023. A total sampling method was employed to select the research participants. Of the 65 patients, 60 (95.24%) experienced ADRs, and the Medication Refill Adherence method indicated an 89.23% adherence rate. Two patients (3.08%) were classified as successful or cured during the data collection period. Chi-square tests revealed no significant relationship between ADRs and medication adherence (p = 0.373) or treatment outcomes (p = 0.120). All demographic and clinical factors (age, gender, comorbidities, treatment combinations, and potential drug interactions) also showed no significant relationships with adherence (p > 0.05). In contrast, treatment combinations showed significant relationships with treatment outcomes (p = 0.013). These findings highlight the importance of medicines optimisation strategies, including proactive ADR management and adherence support, to improve treatment outcomes in DRTB patients.
Kepatuhan Minum Obat, Luaran Klinis dan Kualitas Hidup Pasien Dislipidemia: Studi Potong - Lintang Fauziah, Syifa; Syafhan, Nadia Farhanah; Puspitasari, Atika Wahyu; Arrum Kusumawardani, Larasati
JURNAL RISET KESEHATAN POLTEKKES DEPKES BANDUNG, Online ISSN 2579-8103 Vol 18 No 1 (2026): Jurnal Riset Kesehatan Poltekkes Depkes Bandung
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/juriskesbdg.v18i1.3174

Abstract

Background: Dyslipidemia is a disease that requires long - term drug therapy. High in medication adherence is necessary to achieve the good clinical outcome and quality of life. Objective: This study aimed to provide medication adherence, clinical outcome, and quality of life in dyslipidemia patients and assess the influencing factors. Methods: This study used a cross - sectional design conducted at Universitas Indonesia Hospital. Morisky Medication Adherance Scale-8 (MMAS-8) questionnaire and EQ-5D-5L questionnaire were used to assess patient’s medication adherence and quality of life. Statistical analysis was carried out using the Chi – Square test with confidence interval of 95%. This study involved 81 dyslipidemia patients in the period from September 15th to October 14th 2025. Results: This study showed that 64.2% of patients had high medication adherence. A total of 88.9% of dyslipidemia patients had controlled total cholesterol levels, and 90.1% had a good quality of life. Gender, age, education, comorbidities, number of medications, and duration of therapy did not affect medication adherence, clinical outcomes, or quality of life among dyslipidemia patients. However, duration of therapy was found to be associated with the quality of life of dyslipidemia patients (p=0.049). Conclusion: Most dyslipidemia patients had high medication adherence, controlled total cholesterol levels, and a good quality of life. Duration of therapy was associated with the quality of life of dyslipidemia patients.
Co-Authors Abu Rachman Aditya Wirawan Adityo Susilo, Adityo Agnes Evonella Pangaribuan AGUSDINI BANUN SAPTANINGSIH Aldora, Ghea Shafa Amarila Malik Andi Ayulestari Andi Utari Prasetya Ningrum Andrajati, Retnosari Ariesa Oktamauri Atika Wahyu Puspitasari Azizahwati Bambang Karsono Bambang Wispriyono Bambang Wispriyono Chairunnisa, Dian Fitri Deli Marteka Delila Eliza Dendhi Bagus Andriyanto DENNI JOKO PURWANTO, DENNI JOKO Dinda Bestari Sutantoputri Djuria, Rachmawati Felani Elsa Vera Denida Purba Farmasita Budiastuti, Rizky Fauziyyah, Afina Nur Fitri Nurhayati Fransisca Dhani Kurniasih Galuh Zhafirah Rahmita Hadijah Tahir Hadiwati, Rangkay Hindun Wilda Risni Humaira Issa Imaniar, Rania Imanuel Sianipar Ingrid Faustine July Kamila, Shinta Kusumawardani, Larasati Arrum Meiliani Shara Suria L Muhamad Andhika Fauzi Muhammad Adil Khan Muhammad Adil khan Muhammad Luthfi Aziz MUTIARA JEANY RAHAYU PERTIWI Nadhila Hasna Hanifah Nasution, Izza Aulia Rizqika Nisa Maria Prasetyaningrum, Marchen Pukovisa Prawiroharjo Pukovisa Prawiroharjo, Pukovisa Purnama Putri, Raden Jacinda Yasmin Puspitasari, Atika Wahyu Rachman, Abu Rachmawati Felani Djuria Rani Sauriasari Rani Sauriasari Rani Sauriasari, Rani Retnosari Andrajati Retnosari Andrajati Retnosari Andrajati Retnosari Andrajati Retnosari Andrajati Retnosari Andrajati Retnosari Andrajati Retnosari Andrajati Risni, Hindun Wilda Salsabila, Azzahra Fahira Santi Purna Sari Sari, Kartika Citra Dewi Permata Sidra Noor Sri Wulandah Fitriani Sri Wulandah Fitriani Sri Wulandah Fitriani Sri Wulandah Fitriani, Sri Wulandah Syahrul Fath Thoriq Syifa Fauziah Taufan Harun Habibie Tifany Maulida Candra Vriona Ade Maenkar Wahono, Dwi Edi Yahdiana Harahap Yovita Diane Titiesari