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All Journal Archive of Community Health Jurnal Veteriner Prosiding Seminar Nasional MIPA Jurnal Vektor Penyakit WMJ (Warmadewa Medical Journal) JBN (Jurnal Bedah Nasional) Jurnal Kesehatan Medika Udayana Aesculapius Medical Journal Public Health and Preventive Medicine Archive Jurnal Riset Rumpun Ilmu Kesehatan (JURRIKES) Jurnal Ilmu Kesehatan Masyarakat
K Tangking Widarsa
Program Studi Ilmu Kesehatan Masyarakat, Fakultas Kedokteran Universitas Udayana
Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Journal : Jurnal Veteriner

 1 
Penurunan Kadar Glukosa Darah dan Hitung Sel Kupffer Tikus Hiperglikemik Setelah Pemberian Dekok Daun Salam (INDONESIAN BAY LEAF DECOCTION COULD LOWER FASTING BLOOD GLUCOSE LEVEL ON HYPERGLYCEMIC RATS AND LOWER KUPFFER CELL COUNT) Yuliana .; Tangking Widarsa
Jurnal Veteriner Vol 15 No 4 (2014)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

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Abstract

Diabetes mellitus (DM) is a metabolic syndrome due to pancreas failure to produce insulin, thereforehyperglycemia is the hallmark of DM. There is hyperglycemia in this disease. In the world, there isaround143 million diabetes mellitus patients. One of the deathcause in diabetes mellitus is chronic liver disease.Herbal medicine is thought to give less side effect than sintetic medicine. A traditional plant that hashypoglicemia property is decoction of Indonesian bay leaves. This study was aimed to study effectivity ofIndonesian bay leaf decoction in decreasing blood glucose level, pancreas and liver hemorrhage scores, andKupffer cell count on alloxan-induced Wistar rats. This Control Group Design used twenty four rats (threemonth old). The rats were divided randomly into four groups, i.e.: control, 1 mL of Indonesian bay leafdecoction (0.9 g/kg body weight (BW)), 2 mL of Indonesian bay leaf decoction (1.8 g/kg BW), and 3 mL ofIndonesian bay leaf decoction (2.7 g /kg BW). After one week adaptation the rats were inducedwithalloxan,then pretest for fasting blood glucose test was examined. Treatment was given for ten days and posttestblood glucose test was done afterwards. At the end of the experiment, all rats were sacrificed to collectpancreas, kidney, and liver. Those organs were stained with hematoxylin eosin. Levelof fasting bloodglucose, hemorrhage score, on pancreas and kidney and Kupffer cell count were analyzed by using Anova.In conclusion, Indonesian bay leaf decoction may lower fasting blood glucose level on hyperglycemic rats aswell as Kupffer cell count significantly, but it is not likely to give significant result in lowering of pancreasand kidney hemorrhage scores.
Penurunan Osteoclast Epifysis Tulang Radius Mencit Perimenopause dengan Pemberian Estrogen dan Berenang (OSTEOCLAST COUNT DECREASING ON EPIPHYSIS PART OF RADIUS IN PERIMENOPAUSAL MICE ON ESTROGEN AND SWIMMING TREATMENT) Yuliana .; Ida Ayu Dewi Wiryanthini; Nyoman Mangku Karmaya; Tangking Widarsa
Jurnal Veteriner Vol 13 No 4 (2012)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

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Abstract

Increasing of life age expectancy has risen many health problem. One of the problem is osteoporosis.This disease can be prevented by estrogen and swimming treatment. Estrogen is not safe to be given inlong term. This study aim was to investigate the decreasing of osteoclast count in estrogen and swimmingtreatment. This study uded Pretest-Posttest Control Group Design with fifty two mice (15-16 months old).The mice were divided randomly into 4 groups, i.e. control, estrogen, swimming and combination group.After 90 days treatment, epiphysis of radius bone was sectioned and stained by haematoxyllin eosin.Osteoclast difference between groups were analyzed by using analysis of variance. Mean of osteoclast incontrol group was 0.12±0.1, and three other groups had the same level, i.e. 0,02±0,06. In conclusion, thedecrease of osteoclast count did not have any significant difference between treatment groups.
Pemberian Ekstrak Methanol Daun Paliasa Menurunkan Kadar Glukosa Darah Tikus Hiperglikemik (METHANOL EXTRACT OF PALIASA LEAVES DECREASES BLOOD GLUCOSE LEVEL HYPERGLYCEMIC RATS ) Yuliana .; Tangking Widarsa; Gede Wiranatha
Jurnal Veteriner Vol 14 No 4 (2013)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

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Abstract

Diabetes melitus is a disease that often encountered by Indonesian people. It can cause microvascular andmacrovascular complication. Traditional herbal medicine such as paliasa (Kleinhovia hospita L.) leavesextract can decrease blood glucose. This study was aimed to identify the effectiveness of extract paliasaleaves on blood glucose decreasing for aloxan induced Wistar mice. This Control Group Design used twentyeight mice (three months old). The mice were divided randomly into four groups, i.e. control, paliasa250mg/kg body weight (BW), 500 mg/kg BW, and 750 mg/kg BW. After one week adaptation and induced byalloxan, pretest fasting blood glucose test was done. Treatment was given for two weeks and posttest bloodglucose test was done afterwards. The decrease of fasting blood glucose level was analyzed by usinganalysis of varians. Result showed there was significantly higher level of blood glucose decrease in micewith paliasa extract dose of 750mg/kgBB. Mean level of blood glucose decrease on control group was2.9±0.17, paliasa group with dose 250mg/kgBB was 29.28±1.15, paliasa 500 mg/kgBB was 46.7±2.1, danpaliasa 750mg/kgBB was 74.8±1.88.  In conclusion, extract paliasa treatment can decrease fasting bloodglucose level on hyperglycemic rats.
Co-Authors A Swandewi A. A. Ayumi Witantri Anny Eka Pratiwi Bharata, Made Dwi Yoga Bunganing Eswarya Cokorda Istri Padmi Desak Nyoman Widyanthini Dewa Ayu Agung Alit Suka Astini Dewa Nyoman Wirawan Dewa Nyoman Wirawan, Dewa Nyoman Dwi Masu Putra Dyah Pradnyaparmita Duarsa Erly Sintya Febianingsih, Ni Putu Eka Gede Wiranatha Gusti Ayu Purnama Dewi Gusti Ayu Rusma Windiyana Putri HARI MULYAWAN Hegard Sukmawati, Ni Made Hendry Irawan I Gede Bagus Gita Pranata Putra I Gusti Ngurah Putu Sana I Ketut Labir I Ketut Labir I Ketut Suastika I Ketut Suwiyoga I Made Esa Sadana Yoga I Made Pariartha I Nengah Kapti I Nyoman Mangku Karmaya I Nyoman Sueta I W. Sudarsa I Wayan Darwata I Wayan Darwata I Wayan Suwitra I Wayan Weta I.A.A. Widhiartini Ida Ayu Dewi Wiryanthini Kadek Dean Ariska Aryawangsa Kadek Yulita Dewi Lestari Komang Trisna Sumadewi Luh Gede Sri Yenny Luh Putu Kartika Darmapadmi Maheswari, Luh Putu Dewanda Ni Ketut Sutiari Ni Komang Surya Sanistiasih Budaya Ni Luh Putu Eka Kartika Sari Ni Luh Putu Suariyani Ni Luh Putu Suariyani Ni Made Dian Kurniasari Ni Made Vidya Pratiwi Ni Putu Sri Widhi Andayani Ni Putu Widarini Ni Wayan Septarini Ni Wayan Widhidewi Nyoman Triana Ayati Putu Ayu swandewi astuti Putu Dwiki Damadita Putu Sutisna Rina Listyowati Rina Listyowati, Rina Rini Hendari Rini Hendari, Rini Sagung Putri Permana Lestari MP Seshia Arma Dwi Permata Sri Juharni Sri Juharni, Sri Sri Ratna Dewi Sri Trisnawati Sri Trisnawati Suryawisesa, Ida Bagus Made Viky Yudi Alvian Vivin Sumanti Vivin Sumanti Witari, Ni Putu Diah Yasa, I Nyoman Wawan Tirtha Yuliana Yuliana