Article Per Year (5 Year)
p-Index From 2021 - 2026
4.462
P-Index
This Author published in this journals
All Journal Jurnal Pendidikan Vokasi Medicina E-Jurnal Medika Udayana Jurnal Kesehatan Andalas MNJ (Malang Neurology Journal) Bali Journal of Anesthesiology Adimas : Jurnal Pengabdian Kepada Masyarakat Callosum Neurology Journal : Jurnal Berkala Neurologi Bali ISM (Intisari Sains Medis) : Jurnal Kedokteran DIKEMAS (Jurnal Pengabdian Kepada Masyarakat) Bioscientia Medicina : Journal of Biomedicine and Translational Research Majalah Kedokteran Neurosains Kumawula: Jurnal Pengabdian Kepada Masyarakat Bali Anatomy Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Cermin Dunia Kedokteran Jurnal Locus Penelitian dan Pengabdian Hang Tuah Medical Journal Eduvest - Journal of Universal Studies Neurona Malahayati International Journal of Nursing and Health Science Cermin Dunia Kedokteran
I Putu Eka Widyadharma
Departemen Neurologi, Fakultas Kedokteran Universitas Udayana, Denpasar, Bali
Aerospace Engineering Automotive Engineering Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

Published : 60 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search
Journal : Neurona

 1 
PERBEDAAN LUARAN PASIEN STROKE ISKEMIK AKUT DENGAN LEUKOSIT NORMAL DAN LEUKOSITOSIS Clarissa Tertia; Belinda Orline Olivia Singgih; I Ketut Sumada; Ni Ketut Candra Wiratmi; Putu Eka Widyadharma
NEURONA Vol 36 No 1 (2018)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v36i1.51

Abstract

    DIFFERENCE IN OUTCOME OF ACUTE ISCHEMIC STROKE PATIENT WITH NORMAL LEUKOCYTE AND LEUKOCYTOSISABSTRACTIntroduction: Inflammation is an independent risk factor for ischemic stroke, which needs to be inhibited to reduce worsening occlusion of arteries due to atherosclerotic plaques. Increased leukocyte count is considered an acute damage marker of brain tissue that experiences ischemia and is used to determine the severity and prognosis of acute ischemic stroke.Aims: To analyse association between the number of leukocytes in acute onset ischemic stroke patients during admission and discharge.Methods: A prospective analytical observational study with a cohort design on acute ischemic stroke patients in Wangaya Regional Hospital, Denpasar-Bali between January and September 2018. Clinical manifestations were assessed using National Institutes of Health Stroke Scale (NIHSS). Data was collected through medical records and analysed using Chi-square test and Mann-Whitney.Results: Seventy-six subjects devided into 2 groups;  normal  leucocytes and  leucocytosis group,  38 patients respectively. The normal leucocytes group was dominated with male subject (78.9%) and mean leucocytes count was 7,612/mm3. While leucocytosis group was dominated with female subjects (63.2%) and mean leucocytes count was 12,294/ mm3. Mean NIHSS at admission in normal leucocytes group and leucocytosis group was 5 (moderate) and 8 (moderate) respectively. Mean NIHSS at discharge in normal leucocytes group and leucocytosis group was 3 (low) and 11 (moderate) respectively.Discussion: Patients with acute onset ischemic stroke with normal leukocyte count during admission, tend to have better clinical outcome two times fold compared to the patients with leucocytosis.Keywords: Leukocytes, leucocytosis, acute ischemic stroke, NIHSSABSTRAKPendahuluan: Inflamasi merupakan faktor risiko independen terjadinya stroke iskemik, yang perlu dihambat untuk mengurangi perburukan oklusi pada pembuluh darah akibat plak aterosklerotik. Peningkatan kadar leukosit dianggap menunjukkan kerusakan akut jaringan otak yang mengalami iskemia dan digunakan untuk mengetahui tingkat keparahan dan prognosis stroke iskemik akut.Tujuan Mengetahui hubungan antara kadar leukosit terhadap manifestasi klinis pasien stroke iskemik onset akut pada saat masuk dan keluar perawatan.Metode: Penelitian observasional analitik prospektif dengan rancangan kohort terhadap pasien stroke iskemik onset akut yang dirawat di RSUD Wangaya, Denpasar, pada bulan Januari hingga September 2018. Manifestasi klinis subjek dinilai berdasarkan derajat beratnya stroke menggunakan National Institutes of Health Stroke Scale (NIHSS). Data dikumpulkan melalui rekam medis dan di analisis dengan uji Chi-square dan Mann-Whitney.Hasil: Didapatkan 76 subjek yang dibagi menjadi 2 kelompok, yaitu masing-masing 38 subjek pada kelompok dengan leukosit normal dan kelompok dengan leukositosis. Kelompok subjek leukosit normal, didominasi oleh subjek laki- laki (78,9%) dan rerata kadar leukosit 7.612/mm3, sedangkan pada kelompok leukositosis mayoritas perempuan (63,2%) dan rerata kadar leukosit 12.294/mm3. Rerata skor NIHSS saat masuk pada kelompok leukosit normal adalah 5 (moderat) dan  pada kelompok dengan leukositosis adalah 8 (moderat). Adapun rerata skor NIHSS pada kelompok leukosit normal saat pasien keluar adalah 3 (ringan) dan 11 (moderat) pada kelompok leukositosis.Diskusi: Subjek stroke iskemik akut dengan kadar leukosit awal yang normal cenderung memiliki perbaikan manifestasi klinis pada saat keluar RS dua kali lebih baik daripada subjek dengan leukositosis.Kata kunci: Leukosit, leukositosis, stroke iskemik akut, skor NIHSS
KADAR SUBSTANSI P SERUM TINGGI SEBAGAI FAKTOR RISIKO CHRONIC TENSION TYPE HEADACHE PADA MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS UDAYANA Daniel Siagian; Made Oka Adnyana; Putu Eka Widyadharma
NEURONA Vol 37 No 2 (2020)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v37i2.119

Abstract

HIGH SUBSTANCE P SERUM LEVELS AS RISK FACTOR FOR CHRONIC TENSION TYPE HEADACHE AMONG MEDICAL STUDENT FACULTY OF MEDICINE UDAYANA UNIVERSITYABSTRACTIntroduction: Several studies revealed that serum substance P (SP) levels increase in people with headache, particularly chronic tension-type headache (CTTH). One of the examples of population at risk of CTTH is medical students because of their stressful academic load. Aim: To determine whether high serumSP levels are the risk factors of CTTH among medical students.Methods: A case-control study was conducted to medical students, aged 19 to 21, of the Faculty of Medicine, Udayana University from December 2018 to January 2019. Subjects were classified into case group (with CTTH) and control group (without CTTH). SP serum levels were measured on both groups. Analyses included univariate, bivariate with Fisher's test to calculate relative risk (RR), and multivariate logistic regression analysis.Results: Sixty-two subjects, predominantly female (51.6%), were involved in this study. In the case group, most of the subjects had mild depression (71%), mild stress (93.5%), pericranial tenderness (61,3%), and elevated SP serum levels (83.9%). From the multivariate analysis, a high level of SP serum (≥ 349,06ng/L) was the risk factor of CTTH (adjusted Odds ratio 9.9; 95% CI 1.06-93.16). Besides that, other factors, for example, mild stress, mild anxiety, mild depression, pericranial tenderness, and sleep disturbances, were related to the prevalence of CTTH(p=0.001).Discussion: This study concluded that high serum SP levels significantly increased the risk of CTTH occurrence among medical students.Keywords: Chronic tension-type headache (CTTH), medical student, SP serum levelsABSTRAKPendahuluan: Beberapa penelitian menunjukkan kadar substasi P (SP) serum meningkat pada penderita chronic tension type headache (CTTH). Salah satu populasi yang rentan mengalami CTTH adalah mahasiswa kedokteran karena beban akademik relatif tinggi yang diduga berkaitan dengan stres psikologis.Tujuan: Mengetahui apakah kadar SP serum merupakan salah satu faktor risiko CTTH pada mahasiwa kedokteran.Metode: Studi kasus kontrol dilakukan terhadap mahasiswa Fakultas Kedokteran Universitas Udayana berusia 19-21 tahun pada bulan Desember 2018 hingga Januari 2019. Subjek dikelompokkan ke dalam kelompok kasus (dengan CTTH) dan kontrol (tanpa CTTH), kemudian seluruhnya diperiksakan kadar SP serum. Analisis data dilakukan secara univariat, bivariat dengan uji Fisher untuk menghitung risiko relatif (RR), dan analisis regresi logistik multivariat.Hasil: Sebanyak 62 subjek yang mayoritas perempuan (51,6%) ikut serta dalam studi ini. Pada Pada kelompok kasus, sebagian besar mengalami depresi ringan (71%), stres ringan (93,5%), nyeri tekan perikranial (61,3%), dan memiliki kadar SP serum yang tinggi (83,9%). Berdasarkan analisis multivariat, kadar SP serum tinggi (≥ 349,06ng/L) merupakan faktor risiko CTTH (adjusted rasio Odds 9,9; IK 95% 1,06-93,16). Selain itu, faktor depresi ringan, stres ringan, ansietas ringan, nyeri tekan perikranial, dan gangguan tidur masing-masing berhubungan dengan kejadian CTTH (p=0,001).Diskusi: Kadar SP serum tinggi merupakan faktor risiko terjadinya CTTH pada populasi mahasiswa kedokteran.Kata kunci: Chronic tension type headache (CTTH), mahasiswa kedokteran, substansi P
KADAR GLIAL FIBRILLARY ACIDIC PROTEIN SERUM TINGGI SEBAGAI FAKTOR RISIKO NYERI NEUROPATIK PADA KUSTA TIPE MULTIBASILER Sofyan Faridi; I Made Oka Adnyana; I Putu Eka Widyadharma; Luh Made Mas Rusyati
NEURONA Vol 37 No 4 (2020)
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v37i4.170

Abstract

Introduction : Leprosy is one of the most common causes of non-traumatic peripheral neuropathy in the world. There are many factors causing neuropathic pain in multibacillary (MB) type leprosy, one of which is an increase in serum levels of glial fibrillary acidic protein (GFAP). Aim: To prove high serum GFAP levels is a risk factor for neuropathic pain in MB type leprosy in Sanglah General Hospital Denpasar. Methods: This study was an observational analytic study with a case control design conducted at the Dermato-Venerology Department outpatient and in Pathological Clinic Laboratory in Sanglah General Hospital from November 2019 to January 2020. The sample of this study is all multibacillary leprosy patients with neuropathic pain who met inclusion criteria. A total of 60 patient were willing to participate in this study, the pain scales were measured using DN4 questionnaire and GFAP serum levels were examined. Chi-square test was performed to prove high serum GFAP levels is a risk factor of neuropathic pain in multibacillary leprosy. Results: High serum GFAP levels increase the incidence of neuropathic pain of MB type leprosy 5 times higher than controls (OR 5.72; p = 0.003), anxiety (OR 2.1; p = 0.24), and leprosy reaction (OR 2.2; p = 0.052). Discussion: High serum levels of GFAP is a risk factor of neuropathic pain in MB type leprosy in Sanglah General Hospital Denpasar. Keywords: GFAP, MB type leprosy, neuropathic pain
KONSEP BARU DALAM BIOLOGI MOLEKULER PADA NEUROPATI DIABETIK PERIFER Widyadharma, I Putu Eka; de Liyis, Bryan Gervais
Majalah Kedokteran Neurosains Perhimpunan Dokter Spesialis Saraf Indonesia Vol 41 No 5: Edisi Suplemen Neurona Bekerjasama dengan JogjaCLAN 2025
Publisher : PERDOSNI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52386/neurona.v41i5.859

Abstract

Co-Authors A.A Gde Agung Anom Arie W Abdullah, Fachrul Rizky Adhiyoga Santosa Agung Bagus S. Satyarsa Agung Wiwiek Indrayani Anak Agung Ayu Putri Laksmidewi Anak Agung Ayu Suryapraba Anak Agung Bagus Ngurah Nuartha Angelia Carolin Angga Dwi Saputra Anna Marita Gelgel Aria Wibawa Arimbawa, I Komang Ariswanda, I Gusti Agung Gede Ayu Inten Dwi Primayanti, I Dewa Belinda Orline Olivia Singgih Candra, Alamanda Clarissa Tertia Daniel Siagian de Liyis, Bryan Gervais Desak Ketut Indrasari Utami Devi, Gusti Ayu Putu Giti Livia Dewa Ngurah Suprapta Dewa Putu Gede Purwa Samatra Dian Rizki Fitria Dwijo Anargha Sindhughosa Eric Hartono Tedyanto ERIC HARTONO TEDYANTO Eric Hartono Tedyanto Faldi Yaputra Florence Diana Thomas G, Gayathridayawasi Gede Yoni Komalasari, Ni Luh Gitari, Ni Made Haditya, Yogi hakim, aulia el I Gusti Ngurah Ketut Budiarsa I Ketut Sumada I Komang Arimbawa I Made Jawi I Made Oka Adnyana I MADE OKA ADNYANA I Made Oka Adnyana I Made Pramana Dharmatika I Wayan Niryana Ida Ayu Sri Indrayani Ida Ayu Sri Wijayanti Ida Bagus Kusuma Putra IGN Budiarsa Indah Permata Dewi, Komang Indrasari Utami, Desak Ketut Indrayani, I.A. Sri Juhanna, Indira Vidiari Junaedi, Imam Kesanda, I Made Phala Ketut Widyastuti Kusmarini, Putu Elmamira Kusuma, Yohan Intan Laksmidwei, A A A Putri Lim, Demetria Jesica Limalvin, Nicholas Prathama Luh Made Mas Rusyati Made Oka Adnyana MADE OKA ADNYANA Mahadewi, Ni Putu Ayu Putri Mahmud, Ahmad Ulil Albab Nadia, Hana Jasmine Naomi Valencia Simbolon Ni Kadek Mulyantari Ni Ketut Candra Wiratmi Ni Luh Gede Yoni Komalasari, Ni Luh Gede Yoni Ni Made Dwita Pratiwi Ni Made Susilawathi Ni Made Wira Tania Astarini Ni Nyoman Ayu Dewi Ni Putu Sukarini, Ni Putu Nila Wahyuni Nila Wahyuni Nugraha, Boya P, Sukarini Pramana, Nyoman Angga Krishna Pranitha, Putu Diva Pratiwi, Ni Made Dwita Priandwika, Muhammad Rifki Agung Pusaka, Semerdanta Putra IGN, Purna Putri Rossyana Dewi Putu Emilia Dewi Putu Indah Mahardika Putri Putu Sutirta Yasa, Wayan Raka-Sudewi A. A. Rakhmad Gusta Putra Richard Suherlim Rindha Dwi Sihanto Risky Ilona Saputra Rizaldy Pinzon Rumai, I Made Winarsa Sanad, Sakinah Mar'ie Sanjaya, Feliani Setiawan, Okky Yani Sofyan Faridi Sri Wijayanti, Ida Ayu Sudirman, Dirvi Juliando Sulfan Bagus Setyawan Suryamulyawan, Kadek Adi Susilawathi, Ni Made Sutama, I Komang Reno Sutantohadi, Alief Syah Putra, Muhammad Dio Tedyanto, Eric Hartono Tertia, Clarissa Thomas Eko Purwata Tini, Kumara Tresna Erawan, I Gusti Ngurah Agung Trisnawati, Sri Yenni Vania Rau, Chiquita Putri Wahyu Pribadi Widya Trio Pangestu Widyastuti, Ketut Witari, Ni Putu Y, Yudiyanta Yes Matheos Lasarus Malaikosa Yudha, R. Gaguk Pratama Yudhiatama, Galang Dafa Yuniarni, Ruth Sharon