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UJI AKTIVITAS EKSTRAK BIJI KOPI ROBUSTA (Coffea canephora) dan daun kersen (Muntingia calabura L.) TERHADAP PERTUMBUHAN BAKTERI Propionibacterium acnes Mira Bella Apriance; Riza Dwiningrum; Vicko Suswidiantoro; Mida Pratiwi
Jurnal Kesehatan Yamasi Makassar Vol 10 No 1 (2026): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/3fe6e905

Abstract

Abstrak. Penelitian ini bertujuan untuk menguji aktivitas ekstrak biji kopi robusta (Coffea canephora) dan daun kersen (Muntingia calabura L.) dalam menghambat pertumbuhan bakteri Propionibacterium acnes, serta mengidentifikasi kandungan senyawa aktif dan menentukan konsentrasi kombinasi yang paling efektif. Penelitian ini dilakukan secara eksperimental laboratorium. Ekstrasi dilakukan menggunakan metode maserasi dengan etanol 96%, kemudian dilanjutkan dengan skrining fitokimia  terhadap senyawa alkaloid, flavonoid, tanin, dan saponin. Aktivitas antibakteri dengan metode difusi cakram dengan konsentrasi kombinasi, yaitu 25%:75%, 50%:50%, dan 75%:25%. Zona hambat yang diperoleh dianalisis dengan uji One Way Anova. Hasil menunjukkan bahwa kedua ekstrak mengandung senyawa metabolit sekunder Kombinasi ekstrak biji kopi robusta daun kersen konsentrasi 25% : 75% menghasilkan diameter zona hambat terbesar (4,53±1,71 mm), diikuti oleh konsentrasi 75% : 25% (4,28±2,51 mm) dan 50% : 50% (3,83±1,24 mm), ketiganya tergolong dalam kategori hambat lemah (<5 mm). Analisis statistik menunjukkan data berdistribusi normal dan homogen, namun tidak terdapat perbedaan yang signifikan antar kelompok perlakuan (p > 0,05).  
The Relationship between Level of Knowledge and Self-Medication Behavior for Gastritis among Students of SMK Muhammadiyah 1 Pringsewu Rifa ‘Atul Mahmudah; Wina Safutri; Diah Kartika Putri; Mida Pratiwi
JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI) Vol. 5 No. 2 (2026): JURNAL KESEHATAN, SAINS, DAN TEKNOLOGI (JAKASAKTI)
Publisher : LPPM Universitas Dhyana Pura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36002/js.v5i2.5688

Abstract

Gastritis is a common gastric disorder among adolescents, often caused by irregular eating habits and stress. According to data from the Central Statistics Agency (BPS) of Pringsewu Regency in 2023, gastritis ranked as the fourth most prevalent disease, with 15,687 reported cases. This condition encourages adolescents to practice self-medication; however, inadequate knowledge may lead to inappropriate self-medication behavior. This study aimed to determine the relationship between the level of knowledge and self-medication behavior for gastritis among students of Muhammadiyah 1 Pringsewu Vocational High School. This quantitative analytical study employed a cross-sectional design involving 214 respondents. Data were collected using a validated questionnaire and analyzed through univariate and bivariate analyses using the Chi-Square test. The results showed that most respondents had a good level of knowledge and good self-medication behavior. Statistical analysis revealed a p-value of 0.008 (p < 0.05), indicating a significant relationship between knowledge level and self-medication behavior for gastritis. The findings suggest that the higher an individual's level of knowledge, the better their self-medication behavior. In conclusion, knowledge level is significantly associated with self-medication behavior for gastritis. Therefore, improving health education is essential to ensure that students can practice self-medication appropriately, safely, and rationally.