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All Journal International Journal of Public Health Science (IJPHS) E-Jurnal Medika Udayana JURNAL GIZI INDONESIA Jurnal Kedokteran Brawijaya Jurnal Kesehatan Masyarakat Medical Journal of Indonesia Jurnal Media Gizi Indonesia (MGI) Jurnal Ilmiah Kedokteran Wijaya Kusuma Jurnal Penelitian Kesehatan Suara Forikes Health Notions Jurnal Ilmiah Universitas Batanghari Jambi Amerta Nutrition Media Gizi Kesmas Indian Journal of Forensic Medicine & Toxicology Makara Journal of Health Research Jurnal Widya Medika

Bambang Wirjatmadi

Departemen Of Public Nutrition, Faculty Of Public Health, Airlangga University

Author-ID : 419099

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Efek Preventif Pemberian Ekstrak Kulit Buah Naga Berdaging Super Merah (Hylocereus Costaricensis) terhadap Malondialdehid Tikus Wistar yang Dipapar Asap Rokok Nasution, Ade Saputra; Wirjatmadi, Bambang; Adriani, Merryana
Jurnal Kedokteran Brawijaya Vol 29, No 1 (2016)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Kulit buah naga berdaging super merah Â (Hylocereus costaricensis) merupakan limbah yang sangat jarang dimanfaatkan, biasanya kulit buah naga hanya dibuang begitu saja, padahal mengandung antiosianin yang cukup tinggi. Antosianin yang terkandung dalam kulit buah naga berpotensi dijadikan sebagai alternatif pewarna alami dan antioksidan alami. Penelitian ini bertujuan untuk menganalisis efek pemberian kulit buah naga berdaging super merah terhadap pencegahan kenaikan Malondialdehid (MDA) pada tikus wistar yang diberi paparan asap rokok. Dalam penelitian ini menggunakan lima kelompok, yaitu kelompok kontrol negatif, kelompok kontrol positif, kelompok perlakuan diberi ekstrak 1,575gr/ml, kelompok perlakuan diberi ekstrak 3,150gr/ml dan kelompok perlakuan diberi ekstrak 4,725gr/ml. Kadar MDA dianalisis dengan menggunakan metode TBA (Thiobarbaturic Acid). Penelitian ini dilakukan selama 36 hari, 7 hari pertama diberi ekstrak sesuai dosis, selanjutnya 28 hari kemudian dipapar 2 batang rokok dan diberi ekstrak. Data dianalisis menggunakan uji ANOVA One Way dan LSD. Hasil penelitian menunjukkan kadar MDA pada kelompok positif dengan kelompok pemberian ekstrak 1,575 gr/ml tidak terdapat perbedanyaan nyata (0,079 >0,05). Kadar MDA pada kelompok Â kontrol positif dengan kelompok pemberian ekstrak 3,15gr/ml dan kelompok pemberian ekstrak 4,725gr/ml ada perbedaan nyata (0,00 <0,05). Kelompok pemberian ekstrak 3,15gr/ml dan kelompok pemberian ekstrak 4,725gr/ml dapat mencegah kenaikan kadar MDA pada tikus yang dipapar asap rokok.

Kadar radikal superoksid (O2-), nitric oxide (NO) dan asupan lemak pada pasien hipertensi dan tidak hipertensi Astutik, Pudji; Adriani, Merryana; Wirjatmadi, Bambang
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 3, No 1 (2014)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background: Hypertension closely related to impaired endothelial dependent vasodilation due to a decline in theavailability of nitric oksid (NO) and high fat intake, decreased Nitric Oksid caused due to increased levels ofsuperoksid.Objective: to analyze the differences in the levels of Superoksid Radical (O2-), Nitric oxide (N0) and fat intake inpatients with hypertension and not hypertension .Methods: this research is cross sectional, research amount sampelnya taken at random. 24 respondent patientsconsisting of 12 cases control, and 12 the age of 65 40- tahun.pengambilan samples conducted in outpatient installationregional general hospital Sidoarjo. Done bseline superoksid levels, nitric oxide and recall fat intake.Results: the average rate of Superoksid respondents not hypertension 0.250Â± 0, 034U/mL, 0,314Â± 056U/mLhypertension, Average levels of Nitric oksid respondents not hypertension 116,083Â± 46,962Î¼ M, of which hypertension72,333Â± 40,51Î¼ M, average consumption of fat respondents not hypertension 41,65Â± 8, 32gram, 51,52Â± 6,74gramhypertension . Based on the test results the difference against Superoksid levels of both research groups using a t-testtwo samples are free retrieved the value p < 0,05 (p = 0,004), NO content retrieved the value p < 0,05 (p = 0,023), fatintake obtained the value of p < 0,05 (p = 0,004) which means that there is a meaningful difference in the levels ofSuperoksid, Nitric oxide and the level of fat intake among respondents with no hypertension and hypertension.Conclusion: there is a radical difference in the levels of Superoksid, NO (Nitric Oxide) and fat intake in patients withhypertension and not hypertension.

Hepatoprotective Effect of Mangosteen Peel Extract on Borax-Induced Male Rats Yunita Satya Pratiwi; Bambang Wirjatmadi; Mangestuti Agil; Merryana Adriyani; Supriyadi Supriyadi
International Journal of Public Health Science (IJPHS) Vol 5, No 3: September 2016
Publisher : Intelektual Pustaka Media Utama

The aim of this study was to determine the hepatoprotective effect of mangosteen peel extract (MPE) on borax-induced male rats. Hepatoprotective effect is represented by the variables of liver weight, SGOT (Serum Glutamic oxaloacetic transaminase) and SGPT (Serum Glutamic Pyruvate Transaminase). The true experimental study used randomized separated pretest-posttest control group design. MPE was made with 50% ethanol and 0.5% carboxymethyl cellulose-sodium (CMC-Na) stabilizer solutions. Studied groups included three control groups (positive, negative pretest and posttest) and three experimental groups (MPE dose of 200 mg/kg, 400 mg/kg and 600 mg/kg rats body weight (BW)). Samples consisted 36 male rats. The length of intervention was 16 days by providing borax, and then MPE was started on day 3 (in 3 experimental groups). Results showed that up to 16th day the SGOT tended to decrease (α <0.05), while the SGPT levels was stable, and so was the liver weight. Thus, up to day 16 the MPE was generally able to provide hepatoprotective effects mainly based on the variable SGOT in doses of 200 and 400 mg/kg. It has been proved that liver function of the rats was still relatively normal. This is in relations to the antioxidant potential of the MPE polyphenols.

Heart Disease in Indonesia in 2018: An Ecological Analysis Haqqelni Nur Rosyidah; Bambang Wirjatmadi; Bambang Purwanto
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16316

Broccoli Effects on Hif-1 A in Spermatozoa Cells of Ratsthat Induces Psychological Stress Ahmad Nur Huda; Bambang Wirjatmadi; Bambang Purwanto
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16334

Broccoli Effects on HIF-1 in Heart Endothelial Cells of Rats that Induces Psychological Stress Haqqelni Nur Rosyidah; Bambang Wirjatmadi; Bambang Purwanto
Indian Journal of Forensic Medicine & Toxicology Vol. 15 No. 3 (2021): Indian Journal of Forensic Medicine & Toxicology
Publisher : Institute of Medico-legal Publications Pvt Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37506/ijfmt.v15i3.16341

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The Role of Addition of Vitamin C in Iron Supplementation on Ferritin Serum Levels in Anemia Adolescent Females Nanik Dwi Astuti; Bambang Wirjatmadi; Merryana Adriani
Health Notions Vol 2, No 3 (2018): March
Publisher : Humanistic Network for Science and Technology (HNST)

Prevention of iron deficiency anemia in Indonesia using ferrous sulfas blood-added tablets started since 1997. But iron deficiency anemia is still high, also in young women. Young women are vulnerable because of rapid growth and unhealthy their consumption patterns, which rarely consume fruits and vegetables that are a source of vitamin C. The purpose of this study was to analyze the addition of vitamin C in iron supplementation + folic acid to serum ferritin levels in adolescents females anemia. This research was an experimental quasi research. Design of research was Randomized Pre Post Test Control Group Design, with Double Blind treatment. This study had one treatment group and one control group, each group of 11 samples. The samples were chosen randomly with inclusion and exclusion. The collected data was processed using SPSS program with the analysis of paired t-test and independent t-test to test the difference of serum ferritin level. The results was showed the characteristics of respondents: age (p = 0.430), education of mother (p = 0.942) and nutritional knowledge of respondents (p = 0.928) in the same condition or both groups were had homogeneous characteristics. The pattern and level of food consumption were showed no different between control and traetment groups (p> 0.05). Serum ferritin levels showed difference between the two groups after treatment (p = 0.004). The study was showed vitamin C had role in increasing iron absorption and fill in storage of ferritin formation. Keywords: Anemia, Vitamin C, Iron supplement, Ferritin

Green Tea (EGCG) Decreases Malondialdehide in Oxidative Stress Exposure to Psychological Stress M. Dodi F Priaminda; Bambang Wirjatmadi; Bambang Purwanto; Merryana Adriani
Health Notions Vol 2, No 7 (2018): July
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn20707

Exposure to psychological stress can cause oxidative stress. Provision of exogenous antioxidants is expected to reduce the occurrence of oxidative stress. Green tea with its active ingredient Epigalocatechin Galat is considered to reduce the occurrence of oxidative stress. The purpose of this study was to examine the administration of green tea (EGCG) on the effect decreasing MDA levels against Wistar Strain (Rattus norvegicus) white rats exposed to psychological stress; with Randomized Post Test design of only group design by grouping into 5 groups, with control group and treatment group. Administration of steeping green tea (EGCG) with a single dose. To find out the significant influence of the independent variable on a set of variable group tested Manova. Post hoc testing using LSD (Least Significance Different) was performed to see significant differences between groups. In this study, obtained MDA data with significant decrease at the 6th hours after consum EGCG. Keywords: oxidative stress; green tea, EGCG, malondialdehide

Young khalaal dates (Phoenix dactylifera) effect on blood glucose in alloxan-induced wistar male rats Desty Muzarofatus Sholikhah; Bambang Wirjatmadi; Merryana Adriani
Health Notions Vol 2, No 1 (2018): January
Publisher : Humanistic Network for Science and Technology (HNST)

This study analyzed young dates (Phoenix dactylifera) effect on blood glucose in alloxan-induced male wistar rats. It used a completely randomized design with pre-post test and control group design. The research samples were 25 male white wistar rats that divided into 5 groups: (1) negative control group with no treatment (K1); positive control group with alloxan induction only (K2); treatment group 1 with alloxan induction and 0.25 g/day of young dates treatment (P1); treatment group 2 with alloxan induction and 0.5 g/day of young dates treatment (P2); and treatment group 3 with alloxan induction and 1 g/day of young dates treatment (P3). The result were tested by Kolmogorov-Smirnov normality test (p>0.05), Levene's homogeneity test (p>0.05), followed by General Multivariate Manova test by Wilks' Lambda, between-subject effect test, and LSD (p<0.05). The results indicated that young dates could effectively reduced the blood glucose levels (p = 0.000). The fasting blood glucose level in positive control group (K2) was different from negative control group (K1, p = 0.000) and all treatment groups (P1, p = 0.000, P2, p = 0.000 and P3, p = 0.000). 0.25 g/day of young dates treatment could effectively reduced the fasting blood glucose level in alloxan-induced male wistar rats. Keywords: young dates, blood glucose levels, alloxan

Bee Pollen Effect on Blood Glucose Levels in Alloxan-induced Male Wistar Rats Aprilia Nurcahyaning Rahayu; Bambang Wirjatmadi; Merryana Adriani; Soenarnatalina M.; Dwi Winarni; Sri Hartiningsih
Health Notions Vol 2, No 1 (2018): January
Publisher : Humanistic Network for Science and Technology (HNST)

Bee pollen, as an active ingredient in diabetes mellitus (DM) prevention and treatment, is able to reduce oxidative reactions and to regenerate cells. This study aimed to determine bee pollen effect on blood glucose levels of rats which induced by alloxan. This study used a completely randomized design with Pre-Post Test design and Control Group design. The subjects were 25 male wistar rats which divided randomly into 5 groups: (1) negative control group (non-DM rats); (2) positive control group (DM rats without bee pollen); (3) P1 group (DM rats with 0.25 g/day bee pollen); (4) P2 group (DM rats with 0.63 g/day bee pollen); and (5) P3 group (DM rats with 1.25 g/day bee pollen). Alloxan inducing was used to cause rats under DM or hyperglycemic conditions. The data were analyzed by Manova test and Tukey HSD test. Statistical analysis showed that bee pollen effectively had an effect on decreasing fasting blood glucose (FBG) levels in treatment groups with 0.002. Differences test showed a difference between positive control group and treatment groups, but there was no difference between all treatment groups. However, the bee pollen dosage which giving the lowest average of FBG was 0.25 g on P1 group. Keywords: Bee pollen, Blood glucose level, Alloxan

Co-Authors Ade Saputra Nasution Adriani, Meriyana Adriani, Merriyana Ahmad Nur Huda Andriani, Merryana Annisa Rizka Oktavianita Aprilia Nurcahyaning Rahayu Astuti, Nanik Dwi Aulia, Kharina Auliannisaa, Alifia Bambang Purwanto Bambang Purwanto Bambang Purwanto Cindy Claudia Nurulita Civana Dea Alnanda Cut Athira Sauma D.A. Liona Dewi Damayanti, Adelina Elsa Desy Prasetya, Desy Dwi Putra, Kartika Wahyu Dwi Winarni Etha Rambung Fara Disa Durry Fatifa Asmarani, Fatifa Haqqelni Nur Rosyidah INDROPO AGUSNI Jujuk Proboningsih, Jujuk Kadek Tresna Adhi Kirana, Dhea Sukma Kuntoro Kuntoro M. Dodi F Priaminda M., Soenarnatalina Mangestuti Agil Maria Widijanti Sugeng Meirna Dewita Sari Merryana Adriani Merryana Adriyani Minarni Wartiningsih Mohammad Z. Rahfiludin Nanik Dwi Astuti Novera Herdiani, Novera Novita Eka Hardini Nur Nashriana Jufri Oktovina Rizky Oktovina Rizky, Oktovina Priaminda, M Dodi F Pudji Astutik, Pudji Raharja, Kristian Triatmaja Rahayu, Aprilia Nurcahyaning Rahmi Syarifatun Abidah, Rahmi Syarifatun Retno Larasati Rina Wasesa Aprilia Lazulfa Rinda Istiqumilaily Setiarsih, Dini Sholikhah, Anindya Maratus` Sholikhah, Desty Muzarofatus Soenarnatalina M. Sri Hartiningsih Sri Hartiningsih Sri Sumarmi Supriyadi Supriyadi Suryadinata, Rivan Virlando Susanti, Yuyun Erlina Wardani, Karmila Ayu Yoes P. Dahlan Yunita Satya Pratiwi Zolla Gracia Amardiani

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