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All Journal International Journal of Public Health Science (IJPHS) E-Jurnal Medika Udayana JURNAL GIZI INDONESIA Jurnal Kedokteran Brawijaya Jurnal Kesehatan Masyarakat Jurnal Media Gizi Indonesia (MGI) The Indonesian Journal of Public Health Jurnal Ilmiah Kedokteran Wijaya Kusuma Jurnal Penelitian Kesehatan Suara Forikes Health Notions Jurnal Ilmiah Universitas Batanghari Jambi Amerta Nutrition Media Gizi Kesmas Indian Journal of Forensic Medicine & Toxicology Jurnal Kesehatan Tambusai Makara Journal of Health Research Journal of Medicine and Health Jurnal Widya Medika Preventif : Jurnal Kesehatan Masyarakat

Bambang Wirjatmadi

Department Of Nutrition, Faculty Of Public Health, Universitas Airlangga, Surabaya, Indonesia ; Department Of Clinical Nutrition, Airlangga University Hospital, Surabaya, Indonesia & Department Of Clinical Nutrition, PHC Hospital, Surabaya, Indonesia

Author-ID : 419099

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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The Effect of Dayak Onion Bulb-Stem (Eleutherine Palmifolia (L.,) Merr.) Extract on Blood Glucose Levels of Mouse Suffered Diabetes Mellitus Niluh Arwati; Bambang Wirjatmadi; Merryana Adriani; Soenarnatalina Meilanani; Dwi Winarni; Sri Hartiningsih
Health Notions Vol 2, No 3 (2018): March
Publisher : Humanistic Network for Science and Technology (HNST)

Dayak onions (Eleutherine Palmifolia (L.) Merr.) bulb stem contains phtyochemical contents, which act as antidiabetic compounds, such as eleutherol, eleuthocide A, and eleutherinoside B, as well as antioxidant compounds, which include triterpenoid, poliphenol, and flavonoid. Dayak onions was able to be used as the antidiabetic, since it had the ability to lower the blood glucose level and prevent from the free radicals, thus supressing the oxidative stress condition. This research had purpose to analyze the effect of Dayak onions bulbstem as antioxidant and anti diabetic drugs. The research used experimental method with the population in this research was 25 male white mice strain wistar. The concentration of Dayak onions bulb-stem extracts were 300mg.kgBW-1, 400mg.kgBW-1, and 500mg.kgBW-1. Data analysis used Tukey HSD Test with 95% of significance degree and was continued using manova test (average group ratio test). The result showed that. the extract of Dayak onions bulb-stem had the antidiabetical and antioxidant activity, which could lower the blood glucose levels and malondialdehid on the male white mice strain Wistar with the optimum effective doze of 500 mg.kgBW-1.Keywords: Dayak onions bulb-stem, Blood glucose level, Malondialdehid (MDA)

Effects of Purple Sweet Potatoes on Oxidative Stress Biomarkers in Rats Subjected to Exhaustive Exercise Anindya Mar’atus Sholikhah; Bambang Wirjatmadi; Merryana Adriani
Health Notions Vol 2, No 2 (2018): February
Publisher : Humanistic Network for Science and Technology (HNST)

Oxidative stress is a condition caused by the imbalance between the production of free radicals or ROS and the antioxidants; the level of free radicals is higher than the antioxidants. Exhaustive exercise is one of the causes of this oxidative stress. However, it can be reduced by antioxidants found in purple sweet potatoes (PSP) (Ipomoea batatas L). This study aims to evaluate the effect of two weeks supplementation of PSP extract on rats inducedoxidative stress. Twenty rats were distibuted into four groups consisted five rats each. Rats in the treatments groups were administered PSP extract for two weeks then were forced to swim until exhausted. Bloods from all samples were drawn to see the changes in the levels of malondialdehyde ans superoxide dismutase after two weeks of treatment. The data was then analyzed using descriptive and inferential statistic. The results showed that mean level of MDA and SOD differ significantly (p<0.05) between groups after the administration of PSP extract as well as after exhaustive exercise. The extracts and exhaustive exercise concurrently showed a significant effect on oxidative stress biomarkers (p<0.05). It concluded that PSP extract can protect cells against free radical produced by exhaustive exercise. Keywords: Purple sweet potatoes, Physical activity, Oxidative stress, MDA, SOD

The Role of Nutritional Status, Dietary Pattern and Free Radical in the Insulin Resistance Development Meirna Dewita Sari; Bambang Wirjatmadi; Merryana Adriani
Health Notions Vol 1, No 4 (2017): October-December
Publisher : Humanistic Network for Science and Technology (HNST)

Insulin resistance is an early sign of diabetes type 2 that occurs in situations where target organ sensitivity decreases against insulin. Excess free radicals can be mutually insulin resistance. The purpose of this study was to determine how the effects of insulin can be a determining factor. This study used case control design conducted on 22 outpatients at Clinic University of Muhammadiyah Surabaya during June until July 2017. Data were collected using questionnaires, nutritional status, fasting blood glucose, fasting insulin, and MDA levels. Insulin resistance status using normal HOMA IR method of <2.77. Logistic Regression was used to determine the effect of free radical on the occurrence of insulin resistance. The results showed free radical against insulin resistance at =0.05 with p=0.018. That result means boosting MDA levels also increases the risk of insulin resistance. In addition, the consumption of dietary sources of fat and excessive use of food additives, low fruit intake, BMI values are also factors affecting insulin resistance with p=0.027; p=0.036; and p=0.027. Given the elevated levels of MDA-free radicals can increase the risk of insulin resistance. Applying a healthy lifestyle by consuming fiber-rich foods can prevent the formation of excessive free radicals. Keywords: Insulin resistance, Free radical, HOMA IR

The Influence of Sinbiotic Yogurt on Microscopical Frequent Using Microscopes on the Wistar Rats (Rattus norvegicus) Jayanthi Petronela Janggu; Bambang Wirjatmadi; Merryana Adriani
Health Notions Vol 1, No 3 (2017): July-September
Publisher : Humanistic Network for Science and Technology (HNST)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/hn.v1i3.38

Escherichia coli are a gram-negative bacteria belonging to the normal human intestinal flora. Excessive type of E.coli pathogen bacteria could cause infectious disease for humans. In the gastrointestinal tract, especially in the small intestine, the pathogen that often causes interference is Enteropathogenic Escherichia coli. Growth of pathogenic bacteria could be inhibited by administration of sinbiotic yogurt. Synbiotic yogurt is a yogurt that is supplemented with probiotics and prebiotics. Probiotics used were Lactobacillus bulgarius, Streptococcus thermophiles, Bifidobacterium bifidium with the addition of prebiotics i.e. purple sweet potato containing oligosaccharides. The aims of this study was to saw the effect of giving sinbiotic yogurt to microscopic images of the small bowel of wistar rats. This research was a laboratory experimental research. The subjects consisted of 24 wistar rats divided in the control group (6 tails) and the treatment group (18 tails) divided into 3 groups with 6 each group. The results of group I with histologic features of normal intestinal tissue, group II partial epithelial mucosal epithelium seen erosion, group III with epithelial cell surface epithelial mucosa appear normal and group IV with epithelial surface erosion but, cell regeneration was characterized by increasing goblet cells . The administration of sinbiotic yogurt given E. coli had a good effect of improving the epithelial cells of the small intestine surface by increasing goblet cells.Keywords: Escherichia coli, Sinbiotic yogurt, Small intestinal mucosa

Influence of Cinnamon Extract (Cinnamomum burmanii) Provision on the Reduction of Blood Glucose Level of Hyperglycemic Male Wistar Rats Kharina Aulia; Bambang Wirjatmadi; Merryana Adriani
Health Notions Vol 2, No 3 (2018): March
Publisher : Humanistic Network for Science and Technology (HNST)

The number of patients with hyperglycemia in the world and in Indonesia is estimated to increase rapidly in the next 25 years. The content of cinnamaldehyde, flavonoids, polyphenols, and chromium in cinnamon thought to have an influence of hypoglycemia. This study aimed to determine the influence of cinnamon extract to a decrease of blood glucose levels in hyperglycemic rats induced by a single dose of alloxan as much as 125 mg/kg. This study was laboratory experiment by using RAL (Complete Randomize Design) with Pre-Post Test Control Group Design Research. Experimental animals used were male Wistar rats divided into 5 groups. KN was negative control group. KP was hyperglycemic positive control group. P1 was the first treatment group (a dose of 200 mg/kg). P2 was the second treatment group (a dose of 250 mg/kg). P3 was the third treatment group (a dose of 300 mg/kg). Cinnamon therapy was given orally for 14 days. The results of this research was tested statistically by using One Way ANOVA and showed that there were significant differences between the blood glucose levels in the treatment group with the positive and negative control groups. The conclusion was that the provision of cinnamon extract for 14 days could provide an influence of lowering blood glucose levels. Keywords: Blood glucose, Cinnamon, Hyperglicemia

Bee Pollen Effect on Blood Glucose Levels in Alloxan-induced Male Wistar Rats Aprilia Nurcahyaning Rahayu; Bambang Wirjatmadi; Merryana Adriani; Soenarnatalina M.; Dwi Winarni; Sri Hartiningsih
Health Notions Vol 2, No 1 (2018): January
Publisher : Humanistic Network for Science and Technology (HNST)

Bee pollen, as an active ingredient in diabetes mellitus (DM) prevention and treatment, is able to reduce oxidative reactions and to regenerate cells. This study aimed to determine bee pollen effect on blood glucose levels of rats which induced by alloxan. This study used a completely randomized design with Pre-Post Test design and Control Group design. The subjects were 25 male wistar rats which divided randomly into 5 groups: (1) negative control group (non-DM rats); (2) positive control group (DM rats without bee pollen); (3) P1 group (DM rats with 0.25 g/day bee pollen); (4) P2 group (DM rats with 0.63 g/day bee pollen); and (5) P3 group (DM rats with 1.25 g/day bee pollen). Alloxan inducing was used to cause rats under DM or hyperglycemic conditions. The data were analyzed by Manova test and Tukey HSD test. Statistical analysis showed that bee pollen effectively had an effect on decreasing fasting blood glucose (FBG) levels in treatment groups with 0.002. Differences test showed a difference between positive control group and treatment groups, but there was no difference between all treatment groups. However, the bee pollen dosage which giving the lowest average of FBG was 0.25 g on P1 group. Keywords: Bee pollen, Blood glucose level, Alloxan

Expression of VCAM in Male Wistar Rats (Rattus norvegicus) with Hypercholesterolemia Supplemented with Pumpkin Seeds (Cucurbita moschata Duch) Extract Jujuk Proboningsih; Bambang Wirjatmadi; Kuntoro Kuntoro; Merryana Adriani
Health Notions Vol 2, No 6 (2018): June
Publisher : Humanistic Network for Science and Technology (HNST)

Treatment of cardiovascular diseases tends to be expensive and requires long-term therapy. Investigation about the effect of pumpkin seeds on prevention of endothelial dysfunction of blood vessel has never been reported yet, accordingly, bodies of research are required to know its effectiveness. This study aimed to analyze the expression of Vascular Cell Adhesion Molecule (VCAM) in male Wistar rats (Rattus norvegicus) with hypercholesterolemia supplemented with pumpkin seeds extract (Cucurbita moschata Duch). This was an experimental laboratory study with randomized post-test control group design. The independent variable was pumpkin seeds extract, and the dependent one was expression of VCAM. Data analysis employed chi-square test to test the difference between control and treatment groups. Study results showed that there was significant difference (p=0.000) between VCAM expression in group-K2 (positive control) as compared to group-K1 (negative control) and group-K5 (treatment group-dose 3) α=0.001, whereas no significant difference was found between that of as compared to group-K3 (treatment group-dose 1) α=0.125 and group-K4 (treatment group-dose 2) α=0.05. The study showed reduction of VCAM expression in treatment groups consisted of male Wistar rats with hypercholesterolemia supplemented with pumpkin seeds (Cucurbita moschata Duch) extract. Keywords: Pumpkin seeds, VCAM expression, hypercholesterolemia

TIDAK ADA PERBEDAAN BERAT BAYI LAHIR ANTARA IBU DIABETISI DAN IBU NON-DIABETISI Emi Nur Cholidah; Bambang Wirjatmadi
Media Gizi Indonesia Vol. 10 No. 2 (2015): JURNAL MEDIA GIZI INDONESIA
Publisher : Universitas Airlangga

Diabetes mellitus is a metabolic multisystem disease characterized by hyperglycemia due to abnormalities in insulin secretion and/or insulin work. In pregnancy, diabetes mellitus became one of the risk factor for infant’s high birth weight. The other potential factors are mother’sage, pre-pregnancy nutritional status, pregnancy weight gain, gestational age, and parity. Therefore, the research wanted to analyze the difference of birth weight between diabetic mother and non-diabetic mother. Comparative analytical method was used in this study with cross-sectional design.The sample in this study was 10 diabetic mothers and 10 non-diabetic mothers which was taken by simple random sampling in RSU Haji Surabaya. Independendent T-test was used to analyze the birth weight difference. The result showed that the proportion of hight birth weight were more prevalent in diabetic mothers (50%) than non-diabetic mothers (30%). Independent T-test analysis showed there was no difference in birth weight between diabetic mothers and non-diabetic mothers (p= 0,208). Further reseach is needed to understand birth weight determinant factors, particularly in diabetic mothers. Keywords: Birth Weight Infants, Diabetes mellitus, pregnancy, nutritional status

DAYA TERIMA PROPORSI KACANG HIJAU (PHASEOLUS RADIATA L) DAN BEKATUL (RICE BRAN) TERHADAP KANDUNGAN SERAT PADA SNACK BAR Vyatri Pricilya; Bambang Wirjatmadi; Merryana Andriani
Media Gizi Indonesia Vol. 10 No. 2 (2015): JURNAL MEDIA GIZI INDONESIA
Publisher : Universitas Airlangga

Snack bar is a product made from cereal and nuts that usually consumed between meals. Commercial snack bar contains energy, protein, and ﬁber. The ﬁber content in it is usually 1 gram per 25 grams serving. The ﬁber content is relatively low because food categorized as high ﬁ ber if it has 5 grams per 100 gram products. Therefore, a new innovation to improve its ﬁ ber content is required. Green bean and rice bran are type of food with high ﬁber content that possible to be added in snack bar. The purpose of this research was to determine the acceptability and ﬁ ber content in snack bar. This was true experimental research with complete random design (CRD) with 5 treatments. Organoleptic test to assess acceptability of the snack bar was done by 5 trained panelists and 30 non trained panelists. Fiber contentwas calculated using Indonesia Food Composition Database and also analyzed by proximate test in laboratory. The result showed that formula 3 had the highest score than other formulas. Laboratory result showed ﬁ ber content in formula 3 was 1.98 grams per 25 grams snack bar. The conclusion of this research is the snack bar with proportion of green beans and rice bran has a good acceptability and higher ﬁ ber content compared to commercial snack bar.Keywords: ﬁ ber, green beans, rice bran, snack bar

HUBUNGAN AKTIVITAS FISIK DENGAN KEJADIAN KONSTIPASI PADA LANSIA DI KOTA MADIUN Amelia Dyah Kartika Sari; Bambang Wirjatmadi
Media Gizi Indonesia Vol. 11 No. 1 (2016): JURNAL MEDIA GIZI INDONESIA
Publisher : Universitas Airlangga

Elderly is the fi nal stage in human life which usually begins at age 60 years. Elderly phase characterized by decreased function of the body and more susceptible to diseases. One of the disease that are often experienced by the elderly is constipation. Constipation can be caused by various factors, one of which is lack of physical activity.The purpose ofthis study was to analyze the correlation between physical activity and constipation in Madiun City elderly. The subject, which collected using cluster random sampling and simple random sampling method, was 68 elderly which a week physical activity were scored using Physical Activity Scale for the Elderly questionnaire and constipation rate analyzedby Constipation Scoring System questionnaire. Statistic analysis was done using Spearman Correlation test. Results showed that the majority (73.5%) of respondents did not do enough physical activity, and as much as 66.2% of total respondents had constipation. There was a strong and positive correlation between physical activity and constipation in elderly (p = 0.000; r = 0.557) The conclusion of this study is that elderly in Madiun City who did enough physical activity tend to not have constipation.Keywords: physical activity, constipation, elderly

Co-Authors Ade Saputra Nasution Adriani, Meriyana Adriani, Merriyana Ahmad Nur Huda AMBARWATI, SEPTIANA Amelia Dyah Kartika Sari Anak Agung Gede Sugianthara Andriani, Merryana Anindya Mar’atus Sholikhah Anisah Khoirul Umah Annisa Rizka Oktavianita Aprilia Nurcahyaning Rahayu Arinda Lironika Suryana Arwati, Niluh Astuti, Nanik Dwi Aulia, Kharina Auliannisaa, Alifia Ayuningtyas, Septiadeti Hidayati Bambang Purwanto Bambang Purwanto Bambang Purwanto Cindy Claudia Nurulita Civana Dea Alnanda Cut Athira Sauma D.A. Liona Dewi Damayanti, Adelina Elsa Desy Prasetya, Desy Diana Rizqi Fauziyah Dini Setiarsih Dwi Putra, Kartika Wahyu Dwi Winarni Eganda Garwahusada Emi Nur Cholidah Erliza Anggraini Firdaus Etha Rambung Fara Disa Durry Fatifa Asmarani, Fatifa Hadiar Huriyah Rahma Haqqelni Nur Rosyidah Harisma Harisma Himaya Himaya Ikanov Safitri INDROPO AGUSNI Isaura, Emyr Reisha Jayanthi Petronela Janggu Jujuk Proboningsih, Jujuk Kadek Tresna Adhi Kartika Indaswari Dewi Kartika Wahyu Dwi Putra Kharina Aulia Khoiroh, Ummul Kirana, Dhea Sukma Kuntoro Kuntoro Kuntoro Kuntoro Kurniasari, Nadya Putri Kusuma, Anindita M. Dodi F Priaminda M., Soenarnatalina Mangestuti Agil Maria Widijanti Sugeng Meirna Dewita Sari Merryana Adriani Merryana Adriyani Merryana Andriani Merryna Adriani Minarni Wartiningsih Mohammad Z. Rahfiludin Nabilla Siti Hawa Fatimah Nanik Dwi Astuti Novera Herdiani, Novera Novita Eka Hardini Nur Nashriana Jufri Nuraini, Sekarsari Oktovina Rizky Oktovina Rizky, Oktovina Pratama, Dafa Azhari Priaminda, M Dodi F Pudji Astutik, Pudji Raharja, Kristian Triatmaja Rahayu, Aprilia Nurcahyaning Rahmi Syarifatun Abidah Rahmi Syarifatun Abidah, Rahmi Syarifatun Retno Larasati Retno Larasati Rifka Laily Mafaza Rina Wasesa Aprilia Lazulfa Rinda Istiqumilaily Rivan Virlando Suryadinata Sari, Yulianti Wulan Setiarsih, Dini Setyaningtyas, Stefani Widya Sholikhah, Anindya Maratus` Sholikhah, Desty Muzarofatus Soenarnatalina M. Soenarnatalina Meilanani Sri Hartiningsih Sri Hartiningsih Sri Hartiningsih Sri Sumarmi Stefania W Setyaningtyas Supriyadi Supriyadi Suryadinata, Rivan Virlando Susanti, Yuyun Erlina Vidya Noermalawati Vyatri Pricilya Wardani, Karmila Ayu Yoes P. Dahlan Yunita Satya Pratiwi Yuyun Erlina Susanti Zahirah, Fildza Zolla Gracia Amardiani

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