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All Journal Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Abdi Masyarakat Kita Jurnal Pengabdian Masyarakat (Jupemas) Indonesian Journal of Herbal Science and Innovation
Kharina Septi Lestari
Program Studi S1 Farmasi, Universitas Bhakti Kencana
Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Edukasi Dan Pemanfaatan Tanaman Obat Untuk Kesehatan Masyarakat Rw 05 Dan Rw 06 Desa Cibiru Hilir, Kecamatan Cileunyi, Kabupaten Bandung Pada Bulan November Tahun 2021 Kharina Septi Lestari; Nur Rakhmanto Heryana; Antri Ariani; Anggi Jamiyanti; Aris Suhardiman; Amelia Kandisa
Jurnal Abdi Masyarakat Kita Vol 2 No 2 (2022): Jurnal Abdi Masyarakat Kita
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/asta.v2i2.245

Abstract

There are many medicinal plants that have the potential to be developed as raw materials for herbal medicines but in fact have not been managed and utilized optimally by the community. There are several problems with conventional medicine, including side effects, high drug resistance, and higher prices, which have created a prolonged economic situation that has hit Indonesia. One solution that can be done in maintaining health conditions is using family medicinal plants. The purpose of family medicinal plants is that they can be used as an alternative to conventional medicine that is easy to find, no money to buy and without the need to come to a health facility. The implementation of education and utilization of family medicinal plants was carried out in RW 05 and RW 06, Cibiru Hilir Village, Cileunyi District, Bandung Regency. The number of participants in this activity involved 60 people (men and women) with an age range of 20 to 50 years, consisting of 30 people from RW 05 and 30 people from RW 06. The methods used in this activity were conducting pre-tests, counseling activities, post test, and delivery of medicinal plant seeds to residents. After the educational activities on the use of medicinal plants took place, public knowledge about family medicinal plants increased as seen from the results of the pre-test and post-test.
AKTIVITAS ANTIHIPERTENSI EKSTRAK ETANOL DAUN MATOA (Pometia pinnata J.R.Forst. & G.Forst.) PADA MODEL HEWAN HIPERTENSI YANG DIINDUKSI PREDNISON DAN NaCl Kharina Septi Lestari; Elis Susilawati; Aulia Nurfazri Istiqomah; Silvi Nur Amalia; Widhya Aligita
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 8 No 1 (2023): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v8i1.1103

Abstract

Hypertension is a disease without symptoms that is very dangerous (silent killer) because it is often not realized. Conditions that are not controlled and occur continuously will cause a disease factor related to cardiovascular disease. Empirically, matoa leaves are commonly used as antihypertensive drugs. This study aims to determine the activity of the ethanolic extract of matoa leaves as a diuretic and antihypertensive. Diuretic testing was carried out for 6 hours with urine volume measurement every hour. Each test animal was given warm water as a loading dose, using a comparison (Furosemide 3.6 mg/KgBW) and the matoa leaf ethanol extract test group with doses of 150, 300, and 500 mg/KgBW. Antihypertensive testing was carried out in a preventive manner using Prednisone 1.5 mg/KgBW and NaCl 2%, comparison (Hydrochlorothiazide 2.25 mg/KgBW) and the test group ethanol extract of matoa leaves with doses of 150, 300, and 500 mg/KgBW. given orally for 14 days. The test parameters were urine volume, systolic blood pressure and diastolic pressure. The data obtained were analyzed using One Way ANOVA and Kruskall Wallis. The results showed that the ethanol extract of matoa leaves could increase urine output, and decrease systolic and diastolic blood pressure because it had a comparable activity with the comparison group (p<0.05). A dose of 150 mg/kgBW has the most effective activity as an antihypertensive.
PELATIHAN PEMANFAATAN BAHAN HERBAL SEBAGAI JAMU IMUNOSTIMULAN BAGI KELOMPOK PKK RW 001 DESA MAJASETRA KECAMATAN MAJALAYA KABUPATEN BANDUNG Aulia nurfazri istiqomah; Asep Roni; Kharina Septi Lestari; Fikri Mourly Wahyudi; Agus Miraj Darajat; Novitasari tsamrotul fuadah
Jurnal Pengabdian Masyarakat (Jupemas) Vol 2, No 2 (2021)
Publisher : Universitas Bakti Tunas Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36465/jupemas.v2i2.859

Abstract

Sampai saat ini, dapat dikatakan kita masih berada dalam kondisi pandemic COVID-19, khususnya di Indonesia. Telah kita ketahui bersama bahwa dalam menghadapi pandemic COVID-19 ini kita harus menjaga sistem kekebalan tubuh untuk meminimalisir kemungkinan terpaparnya tubuh oleh virus COVID-19 dan patogen lainnya. Program pengabdian kepada masyarakat ini dilaksanakan di Kp. Pangkalan RW. 001 Desa Majasetra, Kecamatan Majalaya, Kabupaten Bandung berupa pelatihan pemanfaatan bahan herbal sebagai jamu imunostimulan atau peningkat daya tahan tubuh kepada kelompok PKK setempat yang nantinya akan disebarluaskan kepada masyarakat. Dari hasil pelaksanaan kegiatan pengabdian kepada masyarakat ini, warga RW 001 Kp. Pangkalan, Desa Majasetra, Kecamatan Majalaya, Kabupaten Bandung telah menerima pemahaman akan pentingnya menjaga daya tahan tubuh terlebih dalam situasi pandemi dengan memanfaatkan bahan-bahan yang ada di sekitar kita.
Pengaruh Toksisitas Subkronik Ekstrak Etanol Rimpang Pacing (Costus speciosus) terhadap Fungsi Hati pada Tikus Aulia Nurfazri Istiqomah; Siti Kholisatun Nisa; Kharina Septi Lestari
Indonesian Journal of Herbal Science and Innovation Vol. 1 No. 1 (2025): Indonesian Journal of Herbal Science and Innovation
Publisher : PT CENDEKIA SCIENCE AND TECHNOLOGY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64673/ijherbsi.v1i1.1

Abstract

Traditional medicine has been an integral part of healing practices for thousands of years. With its rich biodiversity, Indonesia boasts approximately 30,000 plant species with potential medicinal properties, one of which is the rhizome of Costus speciosus (pacing). This plant is known for its various benefits, including antifungal, antioxidant, anthelmintic properties, and traditional contraceptive use. The aim of this study was to investigate the subchronic toxicity of ethanol extract from pacing rhizomes on liver function in male and female rats. The experiment was conducted using Wistar rats, with two groups (10 males and 10 females per group), which were treated with a 300 mg/kg body weight dose of the extract for 90 days. Liver histology, organ index, and levels of the enzymes SGOT and SGPT were observed. The results indicated that the ethanol extract of pacing rhizomes, at this dose, did not cause significant changes in body weight, liver organ index, or SGOT/SGPT levels in both male and female rats. In conclusion, the study suggests that the ethanol extract of pacing rhizomes at 300 mg/kg body weight for 90 days does not show signs of liver toxicity in rats. These findings support the potential use of pacing rhizomes as a safe ingredient in traditional medicine. However, further studies are needed to assess possible toxic effects and animal mortality over longer durations.
Pengaruh Toksisitas Akut Ekstrak Etanol Rimpang Pacing (Costus speciosus) pada Embrio Zebrafish (Danio rerio) Kharina Septi Lestari; Aulia Utami Widiati; Aulia Nurfazri Istiqomah
Indonesian Journal of Herbal Science and Innovation Vol. 1 No. 1 (2025): Indonesian Journal of Herbal Science and Innovation
Publisher : PT CENDEKIA SCIENCE AND TECHNOLOGY

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.64673/ijherbsi.v1i1.2

Abstract

The Costus speciosus plant, commonly known as pacing, is widely used both as an ornamental plant and in traditional medicine. All parts of the plant, particularly the rhizomes, are known to possess various pharmacological activities, including anti-diabetic, anti-cancer, anti-bacterial, and anti-inflammatory properties. However, with the extensive use of the rhizomes in traditional medicine, it is essential to assess their safety. This study aims to determine the LC50 value of ethanol extract from Costus speciosus rhizomes (EERP) and evaluate its acute toxicity level. The Fish Embryo Acute Toxicity (FET) Test was used to assess toxicity, employing zebrafish (Danio rerio) embryos as the model organism. Zebrafish are chosen because their genetic makeup shares about 60-70% similarity with humans, making them a suitable model for mapping toxic effects. The study involved seven experimental groups: two control groups (negative and positive controls) and five groups treated with varying concentrations of EERP (62.5 ppm, 31.25 ppm, 15.63 ppm, 7.81 ppm, and 3.91 ppm). The results revealed an LC50 value of 11.707 ppm for EERP, indicating that the extract falls under the "slightly toxic" category. These findings provide valuable insights into the potential toxicity of Costus speciosus, which is crucial for determining safe dosage levels in its use as a traditional medicine. Further research is needed to explore the underlying toxic mechanisms of this extract.
Co-Authors Agus Miraj Darajat Amelia Kandisa Anggi Jamiyanti Antri Ariani Aris Suhardiman Aulia Nurfazri Istiqomah Aulia Nurfazri Istiqomah Aulia Nurfazri Istiqomah Aulia Nurfazri Istiqomah Aulia Utami Widiati Elis Susilawati Fikri Mourly Wahyudi Novitasari Tsamrotul Fuadah Nur Rakhmanto Heryana Roni, Asep Silvi Nur Amalia Siti Kholisatun Nisa Widhya Aligita