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Infark Miokard Akut Tanpa Elevasi Segmen ST pada Wanita Usia Muda dengan Ketoasidosis Diabetik Rahmawati, Novi; Prasetya, Indra; Prastya, Andhika
Jurnal Klinik dan Riset Kesehatan Vol 4 No 3 (2025): Volume 4 No 3, Juni 2025
Publisher : RSUD Dr. Saiful Anwar Province of East Java

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jk-risk.04.3.8

Abstract

Diabetic ketoacidosis (DKA) is the primary acute metabolic complication of diabetes mellitus (DM), specifically type 2 DM. Individuals with acute coronary syndrome (ACS) have a twice-higher incidence compared to non-diabetic individuals. In people with DM, ACS is responsible for 75% of mortality. This case report investigates a 34-year-old female patient who presented at the Emergency Department of Saiful Anwar Malang Hospital with acute gastrointestinal symptoms of diarrhea and moderate to severe dehydration. Patients with a history of type 2 DM were first diagnosed at the age of 28. The laboratory tests indicated the presence of high blood sugar levels, metabolic acidosis, and ketone-positive. During DKA hydration management, patients have atypical angina with ECG changes from sinus tachycardia to episodic Total AV Block (TAVB) spontaneous termination, increased cardiac enzyme HS (high-sensitivity) Troponin I. Patients diagnosed with acute Non-elevated Segment ST Myocardial Infarction (NSTEMI) very high risk criteria. The patient performed an immediate invasive strategy and promptly identified stenosis in three coronary arteries, with the target lesion being in the Right Coronary Artery (RCA). Subsequently, a drug-eluting stent was implanted in the osteal to mid RCA. Efficient and timely management strategies that prioritize accuracy and simultaneous therapy for cases of DKA and NSTEMI to achieve optimal outcomes.
Pertimbangan Hakim Dalam Menjatuhkan Putusan Pidana Atas Tindak Pidana Peredaran Uang Palsu (Studi Kasus Nomor 347/Pid.B/2021/PN Smg) Indra Prasetya; Arista Candra Irawati
ADIL Indonesia Journal Vol. 5 No. 1 (2024): Adil Indonesia Jurnal
Publisher : Universitas Ngudi Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35473/aij.v5i1.2972

Abstract

The judge's considerations in imposing a criminal decision on the crime of circulation of counterfeit money (Case Study Number 347/Pid.B/2021/PN Smg) The crime of circulation of counterfeit money is regulated in Law Number 7 of 2011 concerning currency and regulated in Article 244 of the Criminal Code concerning Counterfeiting of currency and paper money, and regulated in Law Number 10 of 1998 concerning Amendments to Law Number 7 of 1992 concerning Banking, money as legal means of payment and illegal money is referred to as counterfeit money. The criminal act of circulating counterfeit money as referred to in the Laws and Regulations so that the judge's sentencing decision gives and imposes on mitigating circumstances and aggravating circumstances for the defendant. This study aims to find out the judge's considerations in imposing criminal decisions on the circulation of counterfeit money and how to convict the circulation of counterfeit money. This study uses a juridical-empirical approach using interview data with Class 1A Semarang District Court judges. The results obtained by the research show that the judge's consideration underlies the existence of an unlawful act to lead to a judge's decision. It can be concluded that: the judge's consideration certainly underlies the facts of the trial after carrying out the trial agenda to be used as the basis for the judge's assessment to give a decision, the judge will assess the facts of the trial with valid evidence that can be accounted for by the Public Prosecutor and the defendant so that the judge gives a decision that is contains certainty, fairness, benefits for all parties. Abstrak Pertimbangan hakim dalam menjatuhkan putusan pidana atas Tindak Pidana Peredaran Uang Palsu(Studi Kasus Nomor 347/Pid.B/2021/PN Smg) Tindak Pidana peredaran uang palsu diatur dalam Undang-Undang Nomor 7 Tahun 2011 tentang mata uang dan di atur dalam Pasal 244 KUHP tentang Pemalsusan mata uang dan uang kertas, dan di atur dalam Uandang-UndangNomor 10 Tahun 1998 tentang Perubahan atas Undang-Undang Nomor 7 Tahun 1992 tentang Perbankan,uang sebagai alat pembayaran yang sah dan uang tidak sah sebagaimana dimaksud sebagai uang palsu. Tindak Pidana peredaran uang palsu sebagaimana dimaksud dalam Peraturan Perundang-Undangan sehingga Putusan Pemidanaan hakim yang memberikan dan menjatuhkan atas keadaan yang meringankan dan keadaan yang memberatkan terdakwa.Penelitian ini bertujuan untuk mengetahui pertimbangan hakim dalam menjatuhkan putusan pidana Peredaran uang palsu danbagaimana penjatuhan pidana peredaran uang palsu,Penelitian ini menggunakan metode pendekatan Yuridis-empiris dengan menggunakan data wawancara kepada HakimPengadilan Negeri Semarang Kelas 1A.Hasil di peroleh penelitian menunjukkan pertimbangan hakim mendasari adanya perbuatan melawan hukum untuk menuju amar keputusan hakim. diperoleh kesimpulan bahwa:pertimbangan hakim tentunya mendasari fakta persidangan setelah melakukan agenda persidangan untuk dijadikan dasar penilaian hakim untuk memberikan keputusan, hakim akan menilai dari fakta-fakta persidangan dengan alat bukti sah yang dapat di pertanggungjawabkan dari Jaksa Penuntut Umum maupun terdakwa sehingga hakim memberikan keputusan yang mengandung kepastian, keadilan, kemanfaatan bagi semua pihak.
Rapid degradation of left ventricular function after permanent right ventricular pacing in patients with high-grade atrioventricular block Setiawan, Dion; Prasetya, Indra; Anjarwani, Setyasih; Rizal, Ardian
Heart Science Journal Vol. 6 No. 1 (2025): Challenges in Managing Acute Heart Failure
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.01.22

Abstract

Background: Permanent right ventricular (RV) pacing is a standard for high-grade atrioventricular (AV) block treatment. However, it may result in left ventricular (LV) dilatation, systolic dysfunction, and heart failure (HF) as a consequence of ventricular dyssynchrony and an abnormal myocardial contraction pattern. Pacing-induced cardiomyopathy (PICM) can develop months or years after implantation of a permanent pacemaker (PPM) in patients who have long-term and high-burden RVP. Case Illustration: We reported a case of a 56 years old Asian female having a record of PPM on VVIR mode implantation due to a high grade AV block presented with shortness of breath and bilateral leg swelling. Conclusion: Echocardiography showed a significant decrease in LV systolic function less than two years after PPM implantation. Coronary angiography showed widely patent vessels; subsequently, His-Bundle Pacing (HBP) was scheduled on the patient.
A 56 Year Old Male with Acute Stent Thrombosis During Percutaneous Coronary Intervention, How to Resolve This Problem? Millisani, Hayla Iqda; Rohman, Mohammad Saifur; Prasetya, Indra; Widito, Sasmojo
Heart Science Journal Vol. 4 No. 3 (2023): The Essensial Role of the Metabolic Syndrome in the Development of Cardiovascul
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2023.004.03.8

Abstract

Background: Acute stent thrombosis is the complete occlusion of a coronary artery of the previously implanted stent. This unusual complication occurs in percutaneous coronary intervention (PCI), development of myocardial ischemia, and poor prognosis for the patient. After PCI, acute stent thrombosiscan occur within 0-24 hours and cause the symptoms like acute coronary syndrome. Incidents of stent thrombosis are about 0.6% to 3.4% for Drug Eluting Stent (DES) implantation, depending on the lesion and patient factors. The etiology of acute stent thrombosis is multifactorial, and early detectioncan reduce the mortality rate.Case Illustration: A 56 yo male visited Rumah Sakit Saiful Anwar Malang with stable angina pectoris (Class III symptoms with medical therapy) planned for elective cardiac catheterization with routine medical treatment. During PCI, he complained the chest pain, and from cine angiography evaluation showed no flow at the diagonal branch because of the acute thrombosis. Then got thrombosuction and got a white thrombus. After the PCI procedure, he got fibrinolytic with streptokinase 1.5 million units for 60 minutes. He was transferred to CVCU for observation and discharged after five days.Conclusion: Acute stent thrombosis is a severe complication during and after PCI because it is related to high mortality. The mechanisms by which ST arises are complex and multifactorial and must be early detection.
Fever-Induced Brugada-Pattern Electrocardiogram Nugraha, Yudha Tria; Prasetya, Indra; Martini, Heny; Rizal, Ardian
Heart Science Journal Vol. 5 No. 1 (2024): Inflammation and Cardiovascular Disease
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.01.7

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Background: The Brugada syndrome is a type of cardiac arrhythmia frequently overlooked because of the dynamic character of the condition. Because it tends to progress into ventricular arrhythmias, it is a disorder that, if left untreated, carries the risk of being deadly. Not only is it essential for the practicing clinician to understand the situations that can disclose the concealed Brugada syndrome, but it is also essential for patients to understand these circumstances so that they can be educated to seek medical assistance quickly. This study aimed to describe the diagnosis and management of fever-induced Brugada pattern electrocardiogramCase presentation: Male in his 42-year-old with a history of intermittent fever for four days before hospital admission. High-degree fever was only relieved by taking antipyretics and was accompanied by nausea and muscle and joint pain. Upon arrival at the emergency department, he denied any complaints of chest pain or discomfort, shortness of breath, orthopnea, PND, leg swelling, palpitation, or syncope. A chest radiograph showed normal cardiac and pulmo (Figure 1); a first electrocardiogram showed Sinus Rhythm, HR 112 bpm, regular, FA normal, HA normal, P wave normal, PR interval 160 msec, QRS 80 msec, QTc 326 msec, Coved ST elevation at lead V1 (1 mm), V2 (3 mm), T inversion at lead V1-V2, suggesting sinus tachycardia with type II Brugada pattern.Conclusion: A Brugada pattern can be exposed to several stimuli, but fever is particularly potent. To assist urgent or emergency follow-up in cardiology, Emergency physicians must be informed of specific ECG findings based on the patient's clinical risk factors. The emergency doctor must be able to tell the difference between this pattern and a typical variation of RBBB, as a delayed diagnosis can have dire consequences.
Hypothermia theraphy in patients post cardiac arrest Yudha, Tria; Prasetya, Indra; Tjahjono, Cholid Tri; Anjarwani, Setyasih
Heart Science Journal Vol. 6 No. 1 (2025): Challenges in Managing Acute Heart Failure
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.01.5

Abstract

Cardiovascular disease is the leading cause of death in several developing countries, and many of these deaths occur before reaching the hospital due to cardiac arrest. Most patients who return to spontaneous circulation (ROSC) and are brought to the hospital experience severe neurological damage during cardiac arrest, and this damage is the cause of in-hospital mortality. Improvements in survival and neurologic improvement of patients with CA have focused on two main therapy areas. The first area is improved education and skills of medical and paramedical personnel to improve perfusion post CA. The second area is a greater emphasis on post-resuscitation care which includes optimizing oxygenation and ventilation, avoiding hypotension, treating causes of CA such as acute coronary ischemia, and initiating hypothermia therapy if necessary, as in the 2020 guidelines and recommendations from the American Heart Association (AHA), International Liaison Committee of Resuscitation, and European Resuscitation Council covering the entire spectrum of post-resuscitation care.  The AHA guidelines 2020 recommend optimizing hypothermia therapy for 24 hours with a target temperature between 320C - 360C in ROSC patients to improve clinical outcomes of neurological status after cardiac arrest. This is contrast to the study of Martinell et al in their research which concluded that there was no significant difference in survival rates within 30 days after cardiac arrest in patients who received either hypothermia therapy or those who did not. Hypothermia therapy, which is currently part of the post-resuscitation care recommendations, has varied variables and remains controversial in its implementation. Based on this, this referent will discuss the effects of hypothermia therapy on post-cardiac arrest patients, the stages, and the practical aspects of implementing hypothermia therapy.
Neutrophil-Lymphocyte Ratio value as a predictor of Troponin Elevation in patients with Non-ST Segment Elevation Acute Coronary Syndrome zunardi, Lutfi hafiz; Anjarwani, Setyasih; Prasetya, Indra; Rahimah, Anna Fuji
Heart Science Journal Vol. 5 No. 1 (2024): Inflammation and Cardiovascular Disease
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub/hsj.2024.005.01.2

Abstract

Acute coronary syndrome (ACS) is a prominent contributor to mortality and morbidity on a global scale, consistently ranking within the top five primary causes. Inflammation is one of the many elements that have a role in the pathophysiology of the development and destabilization of plaque atherosclerosis in ACS. Troponin is a component of a biomarker that signals damage to the heart muscle in ACS patients; however, at the present time, not all medical facilities are able to perform troponin testing. An acute myocardial infarction begins with an initial inflammatory process that generates proinflammatory cytokines at the cellular level. This can be evaluated by the NLR through peripheral blood tests. The NLR as an indication of systemic inflammation has been demonstrated to be associated with poor clinical outcomes, an increased risk of complications, and mortality in ACS patients. In addition, several studies showed that the NLR has prognostic value in patients with ACS. The NLR is a mix of inflammatory markers, which can be a predictor of increased troponin in cases of non-ST segment elevation acute coronary syndrome (NSTEACS) in an emergency room.
Continous renal replacement therapy: revisited Aryanugraha, Teguh; Prasetya, Indra
Heart Science Journal Vol. 6 No. 1 (2025): Challenges in Managing Acute Heart Failure
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.01.7

Abstract

Patients in condition of acute kidney injury (AKI) and critically ill often benefit from renal replacement therapy (RRT). Patient with hemodynamically unstable in cardiac intensive care, such as those with congestive heart failure, acute myocardial dysfunction, or excessive hemodilution during cardiac surgery, continuous renal replacement therapy (CRRT) is considered to be the suitable renal replacement therapy modality. This paper discusses indications, techniques, and CRRT in cardiac critical care.
Use of SAPS 3, APACHE IV, and GRACE as prognostic scores for acute coronary syndrome patients in the cardiovascular care unit Yudha, Tria; Prasetya, Indra
Heart Science Journal Vol. 6 No. 1 (2025): Challenges in Managing Acute Heart Failure
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.01.3

Abstract

A grading system based on disease severity has been widely used in intensive care units (ICUs) since around 1980. These systems are used to predict mortality and assess severity in clinical trials. Simplified Acute Physiology Score 3 (SAPS3) and Acute Physiology and Chronic Health Evaluation Score (APACHE IV) are prognosis ratings that can predict in-hospital mortality within the first hour of ICU care. Although these technologies have been widely employed in the ICU, they have yet to be commonly deployed in the cardiovascular care unit (CVCU) due to different patient populations. Intensive care doctors typically employ the standard prognostic scores, SAPS3 and APACHE IV, which were generated from diverse populations of critically ill patients. Although these scores are the most widely used early versions, APACHE IV and SAPS 3 do not include acute coronary syndrome patients. The Global Registry of Acute Coronary Events (GRACE) score has performed the best; this may be because of its straightforward design, which does not distinguish between individuals with SCA and those without ST-segment elevation. Our review article attempts to evaluate the performance of standard predictor scores, namely SAPS 3, APACHE IV, and GRACE, on patients with cardiovascular emergencies. Thus, these score systems can precisely assess the relationship between mortality prediction scores and outcomes of patients admitted to the CVCU rapidly and comprehensively.    
The complex relationship between arterial carbon dioxide levels and acute heart failure: implications for prognosis and management Afifah, Yuri; Prasetya, Indra; Anjarwani, Setyasih; Pashira, Andranissa Amalia
Heart Science Journal Vol. 6 No. 1 (2025): Challenges in Managing Acute Heart Failure
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.hsj.2025.006.01.2

Abstract

Acute Heart Failure (AHF) can affect carbon dioxide levels in the body by altering the balance between ventilation and carbon dioxide production, leading to either hypocapnia or hypercapnia. Arterial carbon dioxide (CO2) levels are essential for maintaining respiratory function and acid-base balance. However, the relationship between arterial CO2 levels and AHF remains complex and not fully understood. Diverse factors affect arterial CO2 levels in patients with AHF, including neurohormonal activation, respiratory compensation for hypoxemia, and changes in pulmonary perfusion. Hypocapnia, characterized by low arterial CO2 levels (PaCO2 < 35 mmHg), is commonly observed in AHF due to hyperventilation-driven respiratory alkalosis secondary to pulmonary congestion. It showed a strong connection with the survival rates of patients following a cardiac arrest. Nevertheless, elevated levels of carbon dioxide in the blood, known as hypercapnia, with a partial pressure of arterial carbon dioxide (PaCO2) exceeding 45 mmHg, can also arise in the later phases of acute heart failure (AHF), indicating fatigue in respiratory muscles or deterioration in pulmonary edema. Abnormal arterial CO2 levels have been associated with increased morbidity and mortality in AHF patients, serving as a valuable prognostic marker.  
Co-Authors Abadi, Sahlan Adlan El Fatih, Muhammad Afifah, Yuri Agung Sasongko Ahmad Aviv Mahmudi Aji, Nugroho Priyo Anjarwani, Setyasih Anna Fuji Rahimah Arista Candra Irawati Aryanugraha, Teguh Astiawati, Tri Atma Gunawan Bagaswoto, Hendry P. Bahar, Mokhamad Aswin Baskoro, Shalahuddin Suryo Burhan Burhan, Burhan Caesario, Fahreza Cholid Tri Tjahjono Cholid Tri Tjahjono Dadang Suprijatna Danny, Siska S. Dewi U. Djafar, Dewi U. Dewi Utari Djafar, Dewi Utari Dilla Maulida Dyah Puspita Saraswati Dzaki Ilhami, Muhammad Efendi, Rizki Arief Filano, Marco Firdaus, Achmad Jauhar firmansyah, Yoki Habib, Faisal Hakim, Dennis I. Hakim, Dennis Ievan Hedi Pudjo Santosa Hendry Purnasidha Bagaswoto Ilhami, Yose R. Ilhami, Yose Ramda Juzar, Dafsah A. Juzar, Dafsah Arifa Karolina, Wella Kuhn, Corinna Maria Kurnianingsih, Novi Kushandajani . Laukkanen, Noora Julia Lestari, Puspa Martini, Heny Millisani, Hayla Iqda Mohammad S. Rohman Mohammad Saifur Rohman Muhammad Sony Maulana Muzakkir, Akhtar F. Muzakkir, Akhtar Fajar Nita Sari, Nita Noverike, Nikhen Novi Rahmawati Nugraha, Tria Yudha Nugraha, Yudha Tria Nurudinulloh, Akhmad Isna Pamuna, Oktafin Srywati Pashira, Andranissa Amalia Perani Rosyani Prastya, Andhika Primada Qurrota Ayun Priyatno Harsasto Putri, Valerinna Yogibuana Swastika Raden Djuniarsono Rahimah, Anna Fuji Ratna Pancasari Rhiza Amdi, Muh Ririn Handayani Rizal, Ardian Rochmawati, Icmi Dian Rudi, Hasrian Sakti, Pradhika Perdana Saputri, Vemmy Lian Saskia Dyah Handari Satrijo, Budi Setiawan, Dion Setyowati, Danti Utami Siska Suridanda Danny Sungkar, Safir Wanty Eka Jayanti Widito, Sasmojo Windya Harieska Pramujati Wirawan, Hendy Yogibuana, Valerinna Yudha, Tria Zhao, Zihan zunardi, Lutfi hafiz