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The Effect of Melinjo Peel Extract in Activity of Lipoprotein Lipase Enzym of The Rats Fed a Hypercholesterolemia Diet Demitri, Athira
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 7, No 2 (2018): Edisi September 2018
Publisher : Universitas Wijaya Kusuma Surabaya

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Abstract

The intake of saturated fat and cholesterol that comes from food digested in the intestine resulting in free fatty acids, triglycerides, phospholipids, and cholesterol. Triglyceride levels increased can be caused by presence of impaired lipoprotein lipase (LPL) enzyme activity. LPL activity can be increased by flavonoid in plant, like Melinjo peel. The purpose of this study is to measure LPL enzyme activity before and after being given extract of Melinjo peel treatment. This research use true experimental, with study design of pretest posttest control group design. Hypercholesterolemic diet given to rats by oral gavage as much as 1,8 grams for 14 days. Melinjo peel extract were given by oral gavage for 14 days after the hypercholesterolemic diet is given. Statistical analysis used Paired Sample T-Test to compare lipoprotein lipase activity before and after treatment. Then, used MANOVA (Multivariate Analyses of Variance) to see the difference of lipoprotein lipase activity in each group after treatment.Based on statistical analysis showed that there were differences of lipoprotein lipase activity in the hypercholesterolemic diet group, HD+54.15, HD+108.30, and HD+216.60 before and after treatment significant (p. < 0.05). The activity of lipoprotein lipase in the normal diet group compared with the hypercholesterolemic and HD+216.60 group showed a significant difference (p. < 0.05). Melinjo peel extract can increased activity of lipoprotein lipase enzym after treatment, those can be due to the flavonoid in Melinjo peel extract.
PENGARUH PENDIDIKAN GIZI TENTANG POLA MAKAN SEIMBANG MELALUI GAME PUZZLE TERHADAP PENINGKATAN PENGETAHUAN ANAK SDN 067690 KOTA MEDAN Athira Demitri; Ernawati Nasution; Evawany Y Aritonang
Gizi, Kesehatan Reproduksi dan Epidemiologi Vol 1, No 2 (2015): Jurnal Gizi, Kesehatan Reproduksi dan Epidemiologi
Publisher : Gizi, Kesehatan Reproduksi dan Epidemiologi

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Abstract

Balanced diet on elementary student are rarely fulfilled. They tend to only eat foods with few nutrients dominant, such as burgers are high in carbohydrates and fats that can cause obesity. With the existence of such problems, nutrition education made by interested media to facilitate the provision of nutritional information, in particular a balanced diet. The aim of this research is to find out the effect of nutrition education about balanced diet through puzzle game to increase the knowledge of elementary student of SDN 067690 in Medan. The type of this research is quasi experimental with one group pretest posttest design. Total population is 249 children and the number of samples is 45 children. Analysis of data using statistical test of paired t-test, the significant level of 95%. The results showed that children given knowledge puzzle game with pretest scores of elementary student in low category (26.7%) and posttest scores in low category (0.0%). Statistical analysis showed there were differences in knowledge scores after nutrition education through puzzle game (p.= 0,000). The conclusion of this research is there were the effect of nutrition education through puzzle game for the elementary student’s knowledge about balanced diet, which is an increase of elementary student’s knowledge about balanced diet. Suggestions of this research was to implementing the nutrition workers in community health centers to use puzzle game to inform about balanced diet.   Keywords: balanced diet knowledge, puzzle game, elementary student
Pengaruh Konseling Gizi Melalui Media Flipchart terhadap Pengetahuan Keluarga Sadar Gizi Athira Demitri; Agnes Sry Vera Nababan; Yulita Yulita; Susi Yanti Hutabarat
Jurnal Dunia Gizi Vol 5, No 1 (2022): Edisi Juni
Publisher : Study Program of Nutrition, Public Health Faculty, Institut Kesehatan Helvetia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33085/jdg.v5i1.5328

Abstract

Pendahuluan; Perilaku Keluarga Sadar Gizi (Kadarzi) dapat dilaksanakan dengan memperhatikan faktor pendukung dalam perubahan perilaku keluarga, yaitu dengan meningkatkan pengetahuan. Pengetahuan tentang Kadarzi dapat ditingkatkan dengan memberikan informasi melalui konseling gizi. Konseling gizi dapat diberikan dengan media tertentu, salah satunya menggunakan media flipchart. Flipchart menjadi suatu media yang mudah dan murah digunakan, dan dapat dipahami dengan baik oleh sasaran, sehingga mampu meningkatkan pengetahuan. Tujuan; Mengetahui pengaruh pemberian konseling gizi melalui media flipchart terhadap pengetahuan Kadarzi. Metode; Jenis penelitian yaitu quasi experiment, dengan rancangan one group pretest postest design. Sampel pada penelitian ini sebanyak 44 ibu balita, yang berada di wilayah Puskesmas Simarpinggan, Tapanuli Selatan. Besar sampel menggunakan rumus Slovin dan pengambilan sampel dengan cara purposive sampling. Data pretest diambil sebelum intervensi konseling gizi sebanyak satu kali dengan flipchart. Kemudian, setelah 1 minggu diambil data posttest. Analisa data menggunakan uji Wilcoxon. Hasil; Pengetahuan sebelum dilakukannya konseling gizi memiliki nilai rata-rata sebesar 4,68, setelah dilakukannya konseling gizi, pengetahuan meningkat sebesar 8,20. Ada pengaruh konseling gizi melalui media flipchart terhadap pengetahuan ibu balita tentang keluarga sadar gizi dengan nilai p value (0,000). Kesimpulan; Terdapat perbedaan pengetahuan ibu balita tentang Kadarzi sebelum dan sesudah diberikan konseling gizi dengan media flipchart.
Hubungan Konsumsi Sayur Dan Buah Terhadap Kejadian Anemia Pada Remaja Putri Di Kelurahan Mabar Kota Medan Tuty Hertati Purba; Sarah Soromi; Athira Demitri; Yusnina Maisyaroh
SCIENTIA JOURNAL Vol. 11 No. 2 (2022): SCIENTIA JOURNAL
Publisher : Universitas Adiwangsa Jambi

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Abstract

Kurang darah atau anemia adalah kondisi ketika tubuh kekurangan sel darah merah yang sehat atau ketika sel darah merah tidak berfungsi dengan baik. Akibatnya, organ tubuh tidak mendapat cukup oksigen sehingga membuat penderita anemia pucat dan mudah lelah. Penelitian ini bertujuan untuk mengetahui hubungan konsumsi buah dan sayur terhadap kejadian anemia pada remaja putri. Penelitian ini dilakukan di Lingkungan 1 Kelurahan Mabar Kota Medan. Metode penelitian menggunakan penelitian kuantitatif berbentuk observasi analitik dengan pendekatan cross sectional. Teknik pengambilan sampel adalah Purposive sampling. Sampel dalam penelitian ini adalah 39 remaja putri Lingkungan 1 Kelurahan Mabar. Data dianalisis dengan analisis univariat dan bivariat menggunakan uji chi-square. Hasil penelitian menunjukkan variabel konsumsi buah memiliki nilai p= 0,00, artinya variabel konsumsi buah memiliki hubungan yang signifikan dengan kejadian anemia, dan variabel konsumsi sayur memiliki nilai p= 0,00, artinya variabel konsumsi sayur memiliki hubungan yang signifikan dengan kejadian anemia pada remaja putri. Saran peneliti adalah agar orangtua, pihak sekolah dan pemerintah lebih aktif memberikan Tablet Tambah Darah (TTD) kepada remaja terutama remaja putri.
Hubungan Pola Makan Dan Status Gizi Terhadap Kejadian Hipertensi Pada Lansia Di Puskesmas Sultan Daulat Kota Subulussalam Tuty Hertati Purba; Mariyanaq Mariyanaq; Athira Demitri Athira Demitri
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (351.488 KB) | DOI: 10.36490/journal-jps.com.v6i1.75

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Background: Hypertension is a chronic disorder in which blood pressure in the blood vessels rises. Hypertension is characterized as having a systolic pressure of more than 140 mmHg and a diastolic pressure greater than 90 mmHg. The study aimed to assess the impact of food and nutritional status on the prevalence of hypertension in the elderly at Sultan Daulat Health Centre in Subulussalam City. The study was an analytic observational design with a case control. All older adults at the Sultan Daulat Health Centre in Subulussalam City who were hypertensive or not were included in the research. The case sample consisted of 22 hypertensive respondents, while the control sample consisted of 22 non-hypertensive respondents. The chi-square statistical test was used to assess data bivariately The results showed that there was a relationship between diet with a p-value of 0.004 <05 and OR 7.600 (95% CI) 1.732 – 33.347, fat intake with a p-value of 0.001 <05 and OR 13.571 (95% CI) 2.991 – 61.586, sodium intake with a p-value 0.000<05 and OR 12.000 (95% CI) 2.862 – 50.306 and nutritional status with a p-value of 0.002<05 and OR 9.643 (95% CI) 2.362 – 39.365 with the incidence of hypertension in the elderly at the Sultan Daulat Health Centre, Subulussalam. This study's recommendations were intended to regulate a balanced diet, minimize consumption of foods high in fat and sodium, and eat foods high in fiber to control excess body weight.
Faktor-faktor yang berhubungan dengan status gizi pada anak balita di Puskesmas Tandun 1 Kabupaten Rokan Hulu Provinsi Riau Tuty Hertati Purba; Prita Delvia Yollanda; Wanda Lestari; Athira Demitri
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.231

Abstract

Introduction; Toddlers need balanced nutrition so that their nutritional status is good, and the growth process is not hampered. The nutritional status of toddlers can be measured anthropometrically, anthropometric indices that are often used, namely: (weight/age), (height/age), and (weight/height). Objective; This study aimed to determine what factors are associated with the nutritional status of toddlers at Tandun 1 Health Center in Rokan Hulu Regency of Riau Province. Methode ;This is an observational research with a cross sectional study approach. The sampling was done by means of the Stratified Random Sampling Method. The population of this study was mothers who had toddlers aged 0-60 months and the sample in this study was mothers who had toddlers aged 24-60 months. The results of this study indicated that from the variable knowledge with a p value of 0.01 and food intake with a p value of 0.00 there was a significant relationship with a p value <0.05, while for the variable exclusive breastfeeding with a p value of 0.08 and a history of diarrhea with a p value of 0.74 there was no significant relationship with a p value> 0.05 in toddlers at Tandun 1 Health Center, Rokan Hulu Regency, Riau Province. It is expected that the health workers of the Health Center increase efforts to prevent nutritional status problems in toddlers which can be done such as providing information about good nutrition for toddlers and providing additional food to toddlers whose nutritional status is lacking.
Faktor resiko kejadian anemia pada remaja putri di SMAN 2 Moro’o Athira Demitri; Dirman Wati Waruwu; Agnes Sry Vera Nababan; Tuty Hertaty Purba
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.332

Abstract

Anaemia occurs when haemoglobin levels in the blood fall below the typical 12 g/dl. The lack of iron, folic acid, vitamin B12, or protein can cause anaemia. Anaemia is mainly caused by low erythrocyte production and bleeding. This study aims to determine the risk factors of anaemia among female adolescents at SMAN 2 Moro'o. This study employed observational analytics using a case-control design. The population of this study was female adolescents, with a sample size of 64 respondents consisting of a case group of 32 respondents and a control group of 32 respondents, sampled using random procedures with a simple random sampling approach. The data was analysed using univariate analysis and bivariate analysis using the chi-square test and odds ratio. The results showed that there was a risk of knowledge p-value = 0.020 and OR 4.048, iron intake p-value = 0.016 < 0.05 and OR 12.130, menstruation p-value = 0.045 < 0.05 and OR 3.215, and obedience Fe tablets consumption p-value = 0.000 < 0.05 and OR 93.000. This research concludes that knowledge, iron intake, menstruation, and obedience to Fe tablets consumption are the risk factors for anaemia among adolescent females at SMAN 2 Moro'o.
Faktor yang mempengaruhi kejadian anemia pada ibu hamil di Puskesmas Mandrehe Kabupaten Nias Barat Eka Nenni Jairani; Novtiurlina Gulo; Tuty Hertati Purba; Athira Demitri; Yulita Yulita
Journal of Pharmaceutical and Sciences Suppl. 1, No. 1 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i5-si.367

Abstract

Introduction Anemia in pregnancy is a condition when the hemoglobin (Hb) level is <11 g% in the first and third trimesters, while in the second trimester, the hemoglobin level is <10.5 g%. The implications for pregnant women with anemia are abortion, bleeding during childbirth, low birth weight (LBW) babies, congenital disabilities, and babies easily infected and susceptible to suffering from malnutrition. Objective This study aims to determine the factors associated with the incidence of anemia in pregnant women at Mandrehe Health Center, West Nias Regency. Methods This is an analytical research study using a cross-sectional design. The population in this study was 140 pregnant women, while the sample was 104 pregnant women. The sampling technique was done by proportional random sampling. The data analysis technique used the chi-square test. Results showed that there was a relationship between knowledge and anemia with a p-value of 0.008. There was a relationship between diet and anemia with a p-value of 0.007. There was a relationship between parity and anemia with a p-value of 0.012). There was a relationship between adherence to Fe tablet consumption and anemia with a p-value of 0.000. Conclusion Health workers are expected to provide education to pregnant women about making antenatal care visits during pregnancy. In this way, health workers can monitor the diet, parity, and compliance of pregnant women in consuming blood supplements tablets.
Acceptance Of Mochi With Substitution Of Beet Flour Substitution Athira Demitri; Icha Azzah Nabillah; Tuty Hertati Purba; Eka Nenni Jairani; Lutfi Henderlan Harahap
International Journal Of Health Science Vol. 4 No. 2 (2024): July: International Journal of Health
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/ijhs.v4i2.3917

Abstract

Mochiis a typical Japanese food which is quite famous in Indonesia for its chewy texture and semi-wet nature. Mochi comes from the Japanese word for muaci. Objective: To determine the physical and chemical characteristics (color, aroma, taste, texture, water content, ash content, fat, folic acid, potassium) of mochi with the substitution of beetroot flour. Method: This type of research is an experimental study with a Completely Randomized Design (CRD), with 4 treatments and 2 repetitions, resulting in 8 experimental units in making mochi with beet flour substitution. The research was carried out in September 2023 at the Helvetia Health Institute, then chemical tests were carried out at the Bioprocess Engineering Laboratory of the Medan Industrial Chemical Technology Polytechnic. In this research, there are hedonic and hedonic quality then proximate tests. Data analysis used Anova and continued with the Duncan test. Results: The hedonic test shows that the F1 formula is the best formula with an average hedonic test value of 3.80 in the like category, while the hedonic quality test shows that the F1 formula is the best formula with an average hedonic quality test value of 3.72 in the purple, aroma category. typical beet flour, sweet taste and chewy texture. The nutritional content of mochi is 20.72% water content, 3.42% ash content, 8.36% fat, 0.186 mg/gr folic acid, and 8.753 mg/gr potassium. Conclusion: The most preferred mochi based on hedonic tests and hedonic quality is the F1 formulation which can be used as an additional food for teenagers and pregnant women because it contains folic acid (0.186 mg/gr).
Hubungan Ketersediaan Pangan Dan Hygiene Sanitasi Terhadap Kejadian Stunting Pada Anak Usia 24-59 Bulan di Wilayah Kerja Puskesmas Ulu Moro’o Agnes Sry Vera Nababan; Athira Demitri; Eka Nenni Jairani; Yulita Yulita; Yemima Gulo
VitaMedica : Jurnal Rumpun Kesehatan Umum Vol. 2 No. 3 (2024): Juli : VitaMedica : Jurnal Rumpun Kesehatan Umum
Publisher : STIKES Columbia Asia Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62027/vitamedica.v2i3.111

Abstract

. Stunting is a condition of children with a length or height that is less different from children of the same age. Stunting is also a growth and development disorder caused by a lack of nutritional intake, where the results of measuring the nutritional status of children based on the PB / U or TB / U category are at the z-score threshold of -2 SD to -3 SD. The purpose of this study was to determine the relationship between food availability and sanitation hygiene to the incidence of stunting in children aged 24-59 months in the Ulu Moro'o Health Center working area. This type of research is quantitative using analytical observational methods with a cross sectional approach and data analyzed using the Chi Square test. The population of this study were children aged 24-59 months in the Ulu Moro'o Health Center working area, namely 136 children. The sampling technique used simple random sampling of 101 children. Food availability for stunting with a value of p = 0.000 <0.05. Sanitary hygiene against stunting events with a value of p = 0.000 <0.05. There is a relationship between food availability and stunting. There is a relationship between sanitary hygiene and the incidence of stunting in the work area of the Ulu Moro'o Health Center. It is expected that mothers of children aged 24-59 months can meet the availability of food every day so that children can consume nutritious and balanced foods to meet their intake.