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All Journal Jurnal Veteriner Jurnal Kedokteran Syiah Kuala Indonesian Journal of Urology Majalah Obstetri dan Ginekologi The Indonesian Biomedical Journal Majalah Kesehatan FKUB Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Jurnal Respirologi Indonesia Majalah Patologi Indonesia Health and Medical Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Indonesian Journal of Electrical Engineering and Computer Science Majalah Biomorfologi (Biomorphology Journal) Jurnal Layanan Masyarakat (Journal of Public Service) Indonesian Applied Physics Letters Jurnal Pengabdian Masyarakat dalam Kesehatan Indian Journal of Forensic Medicine & Toxicology Jurnal Pengabdian Masyarakat Bhinneka Jurnal Pengabdian Masyarakat Bangsa Folia Medica Indonesiana
Anny Setijo Rahaju, Anny Setijo
Departemen Patologi Anatomi, Fakultas Kedokteran, Universitas Airlangga
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Accuracy of Fine Needle Biopsy (FNAB) in Lymph Nodes Tuberculosis Sari, Aditya Sita; Kurniasari, Nila; Rahaju, Anny Setijo; Kusumastuti, Etty Hary; Rahniayu, Alphania
Health and Medical Journal Vol. 8 No. 1 (2026): HEME January 2026
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v8i1.1875

Abstract

Introduction: Tuberculosis (TB) is an infection caused by Mycobacterium Tuberculosis (Mtb) that can attack various organs such as peripheral lymph nodes. Fine needle aspiration biopsy (FNAB) is often used as one of the modalities of diagnosis of lymph node tuberculosis to determine the management of patients. Objective: The objective of this study is to evaluate the accuracy, efficiency, and effectiveness of FNAB in diagnosing lymph node tuberculosis. The findings will assess whether FNAB can be adopted as a standard diagnostic and management tool for patients with this condition. Methods: This is an observational analytic cross-sectional study in the population of patients with suspicion of lymph node tuberculosis at the Anatomical Pathology Unit of Dr. Soetomo General Academic Hospital Surabaya in one year period. FNAB examination was performed with Modified Grunwald Giemsa (MGG) and Ziehl Nielsen (ZN) staining to detect AFB (Acid Fast Bacilli) organisms, as well as PCR (Polymerase Chain Reaction) of peripheral blood. The results were analysed using Chi square statistic test. Results: The sensitivity, specificity, Positive Predictive Value (PPV) and Negative Predictive Value (NPV) of FNAB examinations were 100%, 33%, 59% and 100%, respectively, meanwhile the sensitivity and specificity of PCR peripheral blood examination were 8% and 70% compared to the ZN examination of the FNA aspiration material. Conclusion: FNAB had a higher sensitivity than PCR of peripheral blood to detect Mycobacterium Tuberculosis infection; on the other hand PCR of peripheral blood had a higher specificity than FNAB to detect Mycobacterium Tuberculosis infection.
Co-Authors Abdurrahman Hasyim Asy’ari Alphania Rahniayu Aniek Meidi, Aniek Aniek Meidy Utami Ari Wanda, Dewi Sartika Ariadna Anggi Pasang Ariani, Grace Arifa Mustika Arifa Mustika Aulia Nur Fadila Budi Harjanto Budi Harjanto Dewi Sartika A. W. Dewi, Rosa Amalia DWI SURYANTO DYAH FAUZIAH, DYAH Eddie Saputra Ferdinant Martinus Djawa Fira Soraya Gondo Mastutik Hadiyyatan Waasilah HERAWATI, LILIK Heriyawati, Heriyawati Heryanto Heryanto Heryanto Heryanto I'tishom, Reny Ilmiah, Khafidhotul Imam Susilo Isnin Anang Marhana Izzan Khalidah Binti Muhamad I’tishom, Reny Katherine Kho Khafidhotul Ilmiah Khafidhotul Ilmiah Krismaningrum, Veronika Intan Kusumastuti , Etty Hary Kusumastuti, Etty Hari KUSUMASTUTI, ETTY HARY Leonita Agustin Hambalie Linda Dewanti Mas`udi, Achmad Fayyad Naibaho, Ardy Hamonangan Nila Kurniasari Nila Kurniasari Novalia Chumaladewi Guntarno Nur Arfian, Nur Octavianda, Yohana Osmalina Nur Rahma PUNGKY MULAWARDHANA, PUNGKY Qonitatillah, Ana Qorib, Mohammad Fathul Rahmi Alia Rahmi Alia Rahmi Alia, Rahmi Renny I’tishom Reza Wangsanagara Ridholia Ridholia Ridholia Ridholia, Ridholia Rifatus Solicha Riries Rulaningtyas Roostantia Indrawati S.Pd. M Kes I Ketut Sudiana . Salman Aziz, Muhamad Abi Sari, Aditya Sita Sheilla Matheos Sita Sari, Aditya Sjahjenny Mustokoweni, Sjahjenny Soetojo Soetojo Solly Aryza Suhartono Taat Putra Tarmono Djojodimedjo Tri Wulanhandarini Trianto, Heru Fajar Tuti Andayani Ummi Hanifah Vicky Sumarki Willy Sandhika Winarno, Winarno Wira Santoso Ongko Wiratama, Priangga Adi Yohana Octavianda