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All Journal Jurnal Gizi dan Pangan Journal of Nutrition College Indonesian Journal of Human Nutrition Medical Laboratory Technology Journal Jurnal Skala Kesehatan Jurnal Kesehatan Tambusai Majalah Cendekia Mengabdi Jurnal Penelitian Multidisiplin Bangsa Abdimerka: Jurnal Pengabdian Masyarakat Merdeka Membangun Negeri
Meilla Dwi Andrestian, Meilla Dwi
Poltekkes Kemenkes Banjarmasin Jurusan Gizi
Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences

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Journal : Medical Laboratory Technology Journal

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Anti-hyperglycemic Effect of Torbangun (Coleus amboinicus Lour) Leaves Extract Through Liver and Muscle Glycogen Deposits in Streptozotocin-induced Hyperglycmic Sprague-Dawley Rats Model Meilla Dwi Andrestian; Rizal Damanik; Faisal Anwar; Nancy Dewi Yuliana
Medical Laboratory Technology Journal Vol. 5 No. 2 (2019): December
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (604.547 KB) | DOI: 10.31964/mltj.v5i2.227

Abstract

The association of liver and muscle glycogen deposits with serum insulin levels, β-cells pancreas, and fasting blood glucose (FBG) of streptozotocin (STZ)-induced hyperglycemic rats receiving Torbangun leaves extract (TE) investigated. The intervention performed on 25 8-week-old Sprague-Dawley rats divided into four groups. Seven rats separated as a normal group (N), and other rats injected with streptozotocin (STZ). Confirmation of hyperglycemic was characterized by fasting blood glucose >126 mg/dl. Treatment group which is NG (hyperglycemic rats); N (normal rats); H-IM (62.5 mg/kg BW metformin); and H-IT (620 mg/kg BW TE) for 14 days. This study revealed that TE significantly decreased FBG levels, increased insulin production, and the amount of liver glycogen deposits (a=0.01). However, the intervention did not significantly increase the amount of muscle glycogen deposits. TE administration improves β-cells, increases the liver and muscle glycogen deposits. TE was shown to have antihyperglycemic activity by improving the β-cell, increasing blood serum insulin levels, decreasing blood glucose levels, and increasing the liver glycogen deposits.
Salıva pH, Carıes and OHI-S Score in Stuntıng Pre-School Chıldren in The Swamp Area Utami, Naning Kisworo; Andrestian, Meilla Dwi; Insana, Aima
Medical Laboratory Technology Journal Vol. 11 No. 2 (2025): December
Publisher : Poltekkes Kemenkes Banjarmasin Jurusan Analis Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31964/mltj.v11i2.688

Abstract

Stunting remains a major global health issue and is associated with impaired physical and cognitive development, as well as increased susceptibility to oral diseases such as dental caries. Environmental factors, including acidic peatland water, may further aggravate oral health conditions among children living in swamp areas. This study aimed to analyze the relationship between salivary pH, dental caries severity (def-t index), and oral hygiene status (OHI-S) in preschool children with stunting living in peatland regions of South Kalimantan, Indonesia. An analytical observational study with a cross-sectional design was conducted involving 32 preschool children aged 2–5 years residing in the working area of the Martapura Timur Public Health Center. Data collection included clinical examination of caries using the WHO criteria, salivary pH measurement with a Krisbow digital pH meter, and assessment of oral hygiene using the Simplified Oral Hygiene Index (OHI-S). Statistical analysis was performed using the Spearman correlation test. The results showed that salivary pH ranged from 5.5 to 7.0, def-t scores ranged from 2 to 8 (mean = 5.34 ± 1.78), and OHI-S scores were 0.00 in 22 children (68.7%) and >0.00 in 10 children (31.3%). A significant association was found between salivary pH and dental caries severity (p = 0.005; α = 0.05), indicating that lower salivary pH is associated with higher caries prevalence. In conclusion, stunted preschool children in peatland areas exhibited acidic salivary conditions and a high caries burden despite relatively good oral hygiene status. These findings highlight the importance of integrating nutritional rehabilitation and oral health education programs to reduce the risk of dental caries in children living in environmentally vulnerable swamp regions.
Co-Authors Afifah, Azizah Nur Afriyani, Herlina Apriyani, Nursari Eka Dewi, Zulfiana Faisal Anwar Hapisah, Hapisah Husnul Hatimah, Husnul Ilham, Verien Raodhatul Insana, Aima Laila Sholehah Mahdalena Mahpolah Mas’odah, Siti Muhamad Rizal Martua Damanik Nancy Dewi Yuliana Netty Netty Netty Netty Niken Pratiwi Pitaloka, Anis Diah Rahmani Rahmani Rosihan Anwar, Rosihan Rusmini Yanti Rutmauli Hutagaul Sajiman Sajiman, Sajiman Syainah, Ermina Utami, Naning Kisworo Zulfiana Dewi Zulfiana Dewi Zulfiana SKM Dewi