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All Journal Indonesian Journal of Tropical and Infectious Disease Oto Rhino Laryngologica Indonesiana INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Majalah Biomorfologi (Biomorphology Journal) Jurnal Layanan Masyarakat (Journal of Public Service) JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH RESEARCH Jurnal Pengabdian Masyarakat dalam Kesehatan Indian Journal of Forensic Medicine & Toxicology Berkala Ilmiah Kimia Farmasi Asian Journal of Health Research eJournal Kedokteran Indonesia Folia Medica Indonesiana
Nyilo Purnami
Departement Of Otorhinolaryngology Head And Neck Surgery, Faculty Of Medicine, Universitas Airlangga, Surabaya, Indonesia
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Earth & Planetary Sciences Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Journal : indonesian journal of medical laboratory science and technology

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Association between postnatal maternal serology and congenital cytomegalovirus infection in neonates with jaundice Wardhani, Puspa; Pamungkas, Joko; Husada, Dominicus; Ernawati, Ernawati; Purnami, Nyilo; Fitriah, Munawaroh; Prasetyani, Reni
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 8 No 1 (2026): Integration of Molecular Approaches in Addressing Drug Resistance and Changing Gl
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v8i1.7737

Abstract

Congenital cytomegalovirus (CMV) infection is one of the most prevalent infections at birth and can lead to severe health complications in neonates. Timely detection is crucial. However, polymerase chain reaction (PCR) testing is often unavailable in numerous healthcare settings. In such cases, maternal CMV antibody testing may assist in identifying at-risk infants. In the development of diagnostic methods to date, there is no single method for detecting CMV infection in pregnant women at all stages of pregnancy. This study examined the relationship between maternal CMV serology after delivery and congenital CMV infection in newborns presenting with symptoms including jaundice, prematurity, or low birth weight. Urine samples from neonates within the first 21 days of life were analyzed for CMV DNA via PCR, while maternal IgG and IgM antibodies were assessed within three weeks after delivery. A total of 87 neonates were examined, with 28 (32.2%) testing positive for CMV DNA. Neonatal jaundice was significantly associated with CMV infection, whereas prematurity and low birth weight were not. Maternal CMV IgM positivity was significantly correlated with neonatal CMV PCR positivity, while maternal IgG did not exhibit a significant relationship. In conclusion, maternal CMV IgM positivity post-delivery may assist in identifying newborns requiring confirmatory PCR testing, particularly in healthcare environments with constrained diagnostic resources.
Co-Authors A Ratna Kartika M, A Ratna Ahmad Suryawan Ahyandi, Syarif Syamsi Airina, Andi Alda, Rieza Rizqy Aldri Frinaldi Alfarika Rosmalia Alfian Nurfaizi Alfian nurfaizi Alfian Nurfaizi Aminuyati Angelina Margaretha Ardiani Anggina Diksita Anita Nuraini Aristya, Meutia Putri artono artono Artono Artono, Artono Asmaradianti, Aryunidya Aulia Sakinah Awalia, Awalia Ayuning Tetirah Ramadhani Baiq Dwi Hadiatul Azni Belanny Dwi Desihartati Berliana Nur Azizah Bintang Napitupulu Brahmono, Aditya Budi Utomo Budi Utomo Cahyani, Makhmudyah Indri Chriscelia Valery So Chriscelia Valery So Cintya Dipta Crysciando Jefryco Putra Dewi Isadiartuti Dewo Aksoro Dominicus Husada Dwi ariningtyas, Ninuk Eddy Bagus Wasito Edith Frederika, Edith Eka Savitri Eka Savitri Ernawati Ernawati Falerina, Rosa Fauzi Helmi Fikri Mirza Putranto Firdha, Azizah Amimathul Fis Citra Ariyanto Fitriah, Munawaroh Galih, Antonius Ghaus, Akbar Hamam, Kusumagani Haryuna, Tengku Siti Hajar Hendra Kurnia Rakhma Hendra Kurnia Rakhma I'tishom, Reny Ika Dewi Mayangsari Ilmi, Avida Marisa Inayasari, Syahwina Indira Syahraya Indra Zachreini Indra Zachreini Izzattisselim, Sabrina Jenny Bashiruddin Jenny Bashiruddin Joko Pamungkas Juliandi Harahap Juliandi Harahap Kote Noordhianta Lelyana Sih Afgriyuspita M, A Ratna Kartika Mahesya, Alvian Wahyu Mahrus A Rahman, Mahrus A Makhmudyah Indri Cahyani Makhmudyah Indri Cahyani Martono Martono Mayangsari, Ika Dewi Myrna Adianti Narottama, Kadek Rama Natasha Supartono Natasha Supartono Ni Made Adnya Suasti Nico Probosutejo Ninuk Dwi Ariningtyas Nugroho, Puguh Setyo Nuniek Nugraheni Nunuk Mardiana, Nunuk Nuraini, Anita Nuramalia, Lady Sherly Nurdiansyah, Achmad Fajar Putra Nurvita, Rani Nurwasis Nurwasis Nuzul Wahyuning Diyah Paulus Liben, Paulus Perdana, Rizka Fathoni Prabowo, Gwenny Ichsan Pralampito, Fajrinka Prasetyani, Reni Priyono, Harim Probosutejo, Nico Pudji Lestari Purwanti, Zamrotu Iva Puspa Wardhani Puspita, Dwi Indah Rahma, Safira Respati Ranakusuma Respati Ranakusuma Retno Handajani Risa Etika, Risa Rizka Fathoni Perdana Rizka Fathoni, Rizka Romdhoni, Achmad Chusnu Rosydiah Rahmawati, Rosydiah S.Pd. M Kes I Ketut Sudiana . Sabrina Izzattisselim Sagung Rai Indrasari Sagung Rai Indrasari Salsabila, Aisyah Nur Saputri, Faradila Budi Selfiyanti Bimantara Septriana, Maya Sholehen, Alif Sofia Tiarini Sri Herawati Sriati Sriati Suhariningsih Sulistiawati Sumarman Sumarman Surarso, Bakti Tamin, Susyana Tiarini, Sofia Tjandra Manukbua Tjandra Manukbua Ummi Imamatal Muttaqin Wardhani, Puspa WINARTO Wungu, Citrawati Dyah Kencono Yoga Rahmadiyanto Yoga Rahmadiyanto Yoga Rahmadiyanto Yussy Afriana Dewi Yussy Afriana Dewi Zamrotu Iva Purwanti Zuhria, Ismi