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RELATIONSHIP OF OHA’S TREATMENT RATIONALITY WITH THERAPY TARGETS ACHIEVEMENT IN TYPE II DIABETES MELLITUS PATIENTS Rizky, Wardhiana Agung; Annisaa, Eva; Dini, Intan Rahmania Eka
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 3 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i3.1188

Diabetes mellitus (DM) is the most common condition in Central Java. Irrational use of drugs can cause various problems, including increased disease morbidity and mortality rates, wasted health costs, and the emergence of undesirable effects. Therefore, this study was necessary to assess the rationality of the treatment. The aim was to describe the rationality of OHAs treatment and to achieve therapy targets, and to understand the relationship between OHA treatment rationality and therapy target achievement in patients with type 2 diabetes mellitus at primary health care in Wirosari District, Grobogan Regency. An analytical observational study used a cross-sectional design, purposive sampling, and chi-square test to establish relationships between variables. The rationale for treating OHAs in patients with type 2 diabetes mellitus at primary health care in Wirosari District, Grobogan Regency, is 47.67% rational and 52.33% irrational. Among the samples, 26.7% reached the therapeutic target, whereas 73.3% did not. The rationality of treating OHAs and achieving therapeutic targets was interconnected (p=0.014). Keywords: HbA1C, rational treatment, therapeutic target, type 2 diabetes mellitus

Quality of life in patients with stage 5 chronic kidney disease and type 2 diabetes: A cross-sectional study Mumtaz, Syakira; Dianingati, Ragil Setia; Annisaa', Eva; Riewpaiboon, Arthorn
Innovation in Health for Society Vol 4 No 2 (2024): July - December
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/ihs.12315

Diabetic Chronic Kidney Disease is a complication of diabetes marked by a progressive decline in kidney function. When kidney function falls below a glomerular filtration rate (GFR) of 15 ml/min (Stage 5), patients require renal replacement therapies, such as hemodialysis. This condition can significantly impact a patient's quality of life. This study aims to identify patient characteristics, assess quality of life, and explore the relationship between patient characteristics and quality of life in individuals with Type 2 Diabetes Mellitus complicated by Stage 5 Chronic Kidney Disease at RSUP Dr. Kariadi Semarang. The research used a cross-sectional design and the KDQoL-SF36 questionnaire for data collection. Results indicate that the patient group was predominantly elderly (90.7%), male (62.8%), married (88.37%), and primarily educated at the primary or secondary level (74.42%). A majority were unemployed (53.49%) and had an income greater than 3.000.000 IDR (62.79%). Most patients had been diagnosed with CKD Stage 5 for ≤12 months (62.79%), were receiving monotherapy for diabetes management (58.14%), and had more than one comorbidity (90.7%). The overall quality of life was rated favorably, with an average score of 72.09%. The study concludes that, while the quality of life is generally favorable, it is not significantly influenced by the specific patient characteristics examined. No correlation was found between these characteristics and the quality of life in patients with Type 2 Diabetes Mellitus and Stage 5 Chronic Kidney Disease at RSUP Dr. Kariadi Semarang. Keywords: Cross-sectional study; kidney disease; prevention; quality of life; type 2 diabetes

Waktu Tunggu Pelayanan Resep Obat dan Faktor yang Memengaruhi di Instalasi Farmasi Rawat Jalan Rumah Sakit Nasional Diponegoro Mumtaz, Ananda Rifda Fairuz; Annisaa', Eva; Dini, Intan Rahmania Eka
Generics: Journal of Research in Pharmacy Vol 5, No 1 (2025): Generics: Journal of Research in Pharmacy, Volume 5, Edisi 1, 2025
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/baf.%v.%i.%Y.%p

Waktu tunggu pelayanan resep obat termasuk salah satu indikator Standar Pelayanan Minimal (SPM) Rumah Sakit pada unit standar farmasi dengan kriteria ≤30 menit untuk resep non racikan dan ≤60 menit untuk resep racikan. Pada kenyataannya waktu tunggu pelayanan resep obat tidak memenuhi SPM Rumah Sakit yang mengakibatkan pasien memilih untuk mengambil obat keesokan harinya, fenomena ini juga terjadi di Instalasi Farmasi Rawat Jalan RSND Semarang. Penelitian ini bertujuan untuk mengetahui waktu tunggu pelayanan resep obat pasien rawat jalan dan mengetahui faktor yang memengaruhi waktu tunggu pelayanan resep pasien rawat jalan di Instalasi Farmasi RSND. Penelitian ini merupakan penelitian observasional analitik menggunakan pendekatan cross sectional berdasarkan hasil observasi waktu tunggu pelayanan resep obat, serta sampel resep responden untuk mendapatkan data jenis pasien, jenis resep obat yang ditebus, dan jumlah item obat dalam resep. Hasil penelitian waktu tunggu pelayanan resep obat pasien rawat jalan di Instalasi Farmasi RSND 82,60% tidak sesuai standar. Hasil analisis menunjukkan faktor jenis resep (p=0,821), jenis pasien (p=0,583), dan jumlah item obat dalam resep (p=0,234) tidak memengaruhi lamanya waktu tunggu pelayanan resep obat di Instalasi Farmasi Rawat Jalan RSND.

Waktu Tunggu Pelayanan Resep Obat dan Faktor yang Memengaruhi di Instalasi Farmasi Rawat Jalan Rumah Sakit Nasional Diponegoro Mumtaz, Ananda Rifda Fairuz; Annisaa', Eva; Dini, Intan Rahmania Eka
Generics: Journal of Research in Pharmacy Vol 5, No 1 (2025): Generics: Journal of Research in Pharmacy, Volume 5, Edisi 1, 2025
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/baf.%v.%i.%Y.%p

Waktu tunggu pelayanan resep obat termasuk salah satu indikator Standar Pelayanan Minimal (SPM) Rumah Sakit pada unit standar farmasi dengan kriteria ≤30 menit untuk resep non racikan dan ≤60 menit untuk resep racikan. Pada kenyataannya waktu tunggu pelayanan resep obat tidak memenuhi SPM Rumah Sakit yang mengakibatkan pasien memilih untuk mengambil obat keesokan harinya, fenomena ini juga terjadi di Instalasi Farmasi Rawat Jalan RSND Semarang. Penelitian ini bertujuan untuk mengetahui waktu tunggu pelayanan resep obat pasien rawat jalan dan mengetahui faktor yang memengaruhi waktu tunggu pelayanan resep pasien rawat jalan di Instalasi Farmasi RSND. Penelitian ini merupakan penelitian observasional analitik menggunakan pendekatan cross sectional berdasarkan hasil observasi waktu tunggu pelayanan resep obat, serta sampel resep responden untuk mendapatkan data jenis pasien, jenis resep obat yang ditebus, dan jumlah item obat dalam resep. Hasil penelitian waktu tunggu pelayanan resep obat pasien rawat jalan di Instalasi Farmasi RSND 82,60% tidak sesuai standar. Hasil analisis menunjukkan faktor jenis resep (p=0,821), jenis pasien (p=0,583), dan jumlah item obat dalam resep (p=0,234) tidak memengaruhi lamanya waktu tunggu pelayanan resep obat di Instalasi Farmasi Rawat Jalan RSND.

Analisis Tingkat Pengetahuan dan Dukungan Keluarga Pasien Hipertensi di Puskesmas Kedaton dan Puskesmas Segala Mider Kota Bandar Lampung Ramadhani, Raihan; Dianingati, Ragil Setia; Annisaa', Eva
Generics: Journal of Research in Pharmacy Vol 3, No 1 (2023): Generics: Journal of Research in Pharmacy, Volume 3, Edisi 1, 2023
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/genres.v3i1.17946

Faktor risiko utama penyakit kardiovaskular adalah hipertensi. Keberhasilan pengobatan pada pasien hipertensi dipengaruhi oleh tingkat pengetahuan dan dukungan keluarga. Penelitian ini bertujuan untuk mengetahui tingkat pengetahuan dan dukungan keluarga pada pasien hipertensi di Puskesmas Kedaton dan Puskesmas Segala Mider Kota Bandar Lampung. Penelitian ini merupakan penelitian observasional analitik dengan pendekatan cross sectional. Sampel penelitian ini adalah pasien hipertensi di Puskesmas Kedaton dan Puskesmas Segala Mider Kota Bandar Lampung pada Januari-Maret 2022. Metode pengambilan sampel yaitu purposive sampling. Pengumpulan data dilakukan menggunakan kuesioner pengetahuan dan dukungan keluarga. Uji statistik yang digunakan yaitu uji Chi-square. Hasilianalisis menunjukkan tingkat pengetahuan mayoritas sampel memiliki pengetahuan baik (36%) dan dukungan keluarga yang baik (36%). Tingkat pengetahuan dan dukungan keluarga pada pasien hipertensi di Puskesmas Kedaton dan Puskesmas Segala Mider Kota Bandar Lampung tergolong baik.

Evaluasi Rasionalitas Penggunaan Obat Golongan Penyekat Beta Pada Pasien Gagal Jantung di Rumah Sakit Daerah K.R.M.T Wongsonegoro Semarang Dini, Intan Rahmania Eka; Annisaa, Eva; Safira, Adella Ghalda
Generics: Journal of Research in Pharmacy Vol 5, No 2 (2025): Generics : Journal of Research in Pharmacy Volume 5, Edisi 2, 2025
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/genres.v5i2.25626

Gagal jantung merupakan salah satu penyakit kardiovaskuler yang ditandai dengan kegagalan memompa darah dan oksigen keseluruh tubuh. Salah satu terapi yang digunakan pada gagal jantung adalah antihipertensi, yaitu golongan penyekat beta. Ketidakrasionalan penggunaan penyekat beta akan menimbulkan berbagai macam terjadinya efek obat yang tidak diinginkan serta ketidaktercapaian target terapi. Penelitian ini bertujuan melakukan evaluasi rasionalitas penggunaan obat penyekat beta untuk memberikan gambaran penggunaan penyekat beta umumnya dan memberikan masukan untuk perbaikan penggunaan obat dimasa yang akan datang. Penelitian dilakukan di Rumah Sakit Daerah K.R.M.T Wongsonegoro Kota Semarang dengan rancangan penelitian cohort retrospektif. Sampel merupakan pasien gagal jantung rawat jalan yang menggunakan obat penyekat beta dan diambil dengan metode simple random sampling. Hasil penelitian menunjukkan 91% pasien gagal jantung di Rumah Sakit Daerah K.R.M.T Wongsonegoro tahun 2022 menggunakan obat golongan penyekat beta secara rasional.

Evaluasi Rasionalitas Penggunaan Obat Golongan Penyekat Beta Pada Pasien Gagal Jantung di Rumah Sakit Daerah K.R.M.T Wongsonegoro Semarang Dini, Intan Rahmania Eka; Annisaa, Eva; Safira, Adella Ghalda
Generics: Journal of Research in Pharmacy Vol 5, No 2 (2025): Generics : Journal of Research in Pharmacy Volume 5, Edisi 2, 2025
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/genres.v5i2.25626

Gagal jantung merupakan salah satu penyakit kardiovaskuler yang ditandai dengan kegagalan memompa darah dan oksigen keseluruh tubuh. Salah satu terapi yang digunakan pada gagal jantung adalah antihipertensi, yaitu golongan penyekat beta. Ketidakrasionalan penggunaan penyekat beta akan menimbulkan berbagai macam terjadinya efek obat yang tidak diinginkan serta ketidaktercapaian target terapi. Penelitian ini bertujuan melakukan evaluasi rasionalitas penggunaan obat penyekat beta untuk memberikan gambaran penggunaan penyekat beta umumnya dan memberikan masukan untuk perbaikan penggunaan obat dimasa yang akan datang. Penelitian dilakukan di Rumah Sakit Daerah K.R.M.T Wongsonegoro Kota Semarang dengan rancangan penelitian cohort retrospektif. Sampel merupakan pasien gagal jantung rawat jalan yang menggunakan obat penyekat beta dan diambil dengan metode simple random sampling. Hasil penelitian menunjukkan 91% pasien gagal jantung di Rumah Sakit Daerah K.R.M.T Wongsonegoro tahun 2022 menggunakan obat golongan penyekat beta secara rasional.

The Relationship Between Pharmacist Workload and the Clinical Pharmacy Services Quality of Kulon Progo Regency Dewi, Dina Nurlita; Annisaa', Eva; Dianingati, Ragil Setia
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 15, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.93714

Background: Clinical pharmacy service activities are the decisive roles of pharmacists in ensuring patient safety and quality of life, so there is a need for quality control in their implementation. However, several studies classify the clinical pharmacy services quality at primary health centers as needing improvement. On the other hand, pharmacists at primary health centers in Kulon Progo are overburdened, exceeding the standard rasio.Objectives: This study aims to determine the relationship between the pharmacists workload and the clinical pharmacy services quality.Methods: This study is an analytic observational study with a retrospective and prospective approach. The research participants are five pharmacists from the three sample primary health centers. The pharmacist's workload was measured using the daily log workload form, while the clinical pharmacy services quality was measured using ten indicators of clinical pharmacy service quality. The pharmacist workload is classified into heavy (>80%), moderate (60-80%), or light (<60%) categories. Meanwhile, the quality of clinical pharmacy services is classified into proper (>75%), fair (56-75%), or poor (<56%). The relationship between pharmacist workload and clinical pharmacy service quality was analyzed using the Somers correlation test.Results: The pharmacists’ workload at Sentolo I, Temon I, and Galur II primary health centers, respectively, is heavy (94.05%), heavy (84.55%), and moderate (79.91%). The clinical pharmacy services quality at Sentolo I, Temon I, and Galur II primary health centers, respectively, were fair (56.57%), fair (69.21%), and proper (79.05%). Somers test results show a significant relationship (p=0.014) between the pharmacists’ workload and the clinical pharmacy services quality. The correlation coefficient obtained is -1,000.Conclusion: There is a significant relationship between pharmacist workload and clinical pharmacy service quality.

The role of innovative technology to improve patient centered care Nabilla, Fira; Krongthaeo, Suphanna; Dianingati, Ragil Setia; Annisaa', Eva
Innovation in Health for Society Vol 1 No 1 (2021): January - June
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/ihs.5290

Chronic disease is a long term disease. Treatment performed by patients is also routine and continuous to achieve therapeutic success as well as to avoid complications that can be occurred. Adherence is an important factor to reduce complications of chronic disease. There are some efforts that need to do to increase compliance, such as providing information about drug usage from health providers. The use of technology can also be an option as a facility to increase compliance, such as using audiovisual media as an additional means of providing information and short message services or a mobile application for medication reminders on smartphones. This article provides an overview of the role of technology in increasing adherence to patients especially those who are suffering from chronic disease. This article is based on a literature study from some literature or research results. The reviewed literature shows that the use of video in providing information about drugs, sending short messages, and the use of mobile medication reminders to take medication has an effect on increasing adherence significantly in chronic disease patients. The use of technology is effective and efficient in increasing adherence of chronic disease patients.

Controlling medication nonadherence in chronic illness Kurniadewi, Komang Sukmaloka; Annisaa', Eva; Thuy, Luu Thi
Innovation in Health for Society Vol 1 No 1 (2021): January - June
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/ihs.5293

Patient adherence during the treatment period must be considered because patient adherence plays an important role in achieving therapeutic success, especially for chronic diseases. Treatment non-adherence is a common and complex problem. Failure to follow a treatment schedule can lead to major health complications, including death. Several interventions are needed to control patient non-adherence. Several interventions can support and improve patient adherence. These include digital interventions, increasing patient knowledge and understanding of the treatment undertaken with counseling, and Drug Information Services (PIO). They provide educational leaflets, digital pillbox reminders, Pill Cards; family support; diaries; keeping treatment commitments. Based on this, it is necessary to have an intervention method in terms of education (educational), behavior (behavior), and attitude (affective) to achieve patient adherence and the success of chronic disease therapy. Keywords: Non-adherence; treatment; chronic disease control; medication; patient care

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