Claim Missing Document
Check
Articles

Dhikr Relaxation Training in Pregnant Women Classes In Purbosari Posyandu Purbayan Village Wahyuni, Endang Sri; Mahmudah, Irvina Nurul; Rahmawati, Ai; Handayani, Juleha Duwi; Wardani, Anindya Kusuma; Cahyani, Renata Fina Antika
Journal of Community Services and Engagement: Voice of Community (VOC) Vol. 3 No. 1 (2023)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/voc.v3i1.2240

Abstract

Pregnancy is a vulnerable period with psychological disturbances in the mother. Anxiety can arise due to worries about the pregnancy and the fetus it contains. Especially when the Covid-19 pandemic emerged, causing anxiety for pregnant women, especially the fear of being infected with Covid-19. The aim of PKM (community service) activities is to improve skills in performing dhikr relaxation techniques in pregnant women. Method of Implementation: The partner for this PKM activity is the class of pregnant women at Posyandu Purbosari in Purbayan Village, Sukoharjo district. It is carried out by holding training using lecture and discussion methods, simulations and demonstrations. Then the pregnant women are accompanied to practice dhikr relaxation technique skills. The training conducted has been able to increase the ability of pregnant women to relax dhikr by 100%. The average anxiety level of pregnant women measured by the HARS scale is a score of eight, meaning that pregnant women are in the mild anxiety category. Based on the interview results, the majority of pregnant women said they felt calmer and more relaxed after doing dhikr relaxation exercises. Pregnant women are committed to continuing the practice independently using the dhikr relaxation guide video at their respective homes. Conclusion: Pregnant women are able to practice the dhikr relaxation method taught, feel more relaxed and calm after doing the training. The results of the evaluation in the last week showed that mothers were able to do dhikr relaxation exercises independently at their respective homes using the video guide provided.
Oxidative Stress in Pre-Eclampsia: Bibliometric Visualization Studies and Analysis Sri Wahyuni, Endang; Wiyono, Nanang; Maryatun, Maryatun; Nurul Mahmudah, Irvina; Duwi Handayani, Juleha; Lutfatul Jannah, Safella
Jurnal Kebidanan Indonesia Vol 16, No 2 (2025): JULI
Publisher : STIKES Mamba'ul 'Ulum Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36419/jki.v16i2.1459

Abstract

Background: Preeclampsia is a major cause of death and maternal health problems in the world. Preeclampsia can be triggered by an increase in free radicals which cause oxidative stress. Aim: This study aimed to visually map research publications on the mechanisms of oxidative stress in preeclampsia based on bibliometric analysis. Methods: Systematic Literature Review research design with bibliometric analysis. VOSviewer, Publish or Perish (PoP), and Microsoft Excel resources were used. The database was retrieved from Scopus using the keywords: preeclampsia AND "oxidative stress" AND mechanism as input. Results: The Scopus database revealed a total of 685 published publications on the effects of oxidative stress on preeclampsia from 1996 to 2022. Annual publishing growth is on rising, with 2022 showing the greatest growth rate at 11.68%. The United States has the highest percentage of articles in the world, with a total of 25.8%. The most prolific author is Davidge, ST, with 14 documents. "The effects of oxidative stress on female reproduction: a review", is the most influential article with 928 citations. The International Journal of Molecular Sciences is the most successful journal, with 30 publications and a total link strength of 3988. The University of Mississippi Medical Center is the main institution's research site, with 26 publication documents. The most extensively explored terms are preeclampsia and oxidative stress. Conclusion: The mechanisms of oxidative stress in preeclampsia in the network map were categorized into 5 clusters based on co-occurrence, and “oxidative stress” was the most highlighted term not only in cluster 1 but throughout the network
Potensi buah delima (punica granatum) sebagai terapi adjuvan preeklampsia: A scoping review Wahyuni, Endang Sri; Firrahmawati, Lely; Mahmudah, Irvina Nurul; Handayani, Juleha Duwi
Holistik Jurnal Kesehatan Vol. 19 No. 5 (2025): Volume 19 Nomor 5
Publisher : Program Studi Ilmu Keperawatan-fakultas Ilmu Kesehatan Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/hjk.v19i5.616

Abstract

Background: Preeclampsia is a leading cause of maternal mortality and a global health problem. Preeclampsia can be triggered by increased free radicals, which cause oxidative stress, endothelial dysfunction, and other organ damage. However, to date, no therapy has been proven to prevent preeclampsia other than pregnancy termination. A scoping review is needed to gather evidence related to the use of pomegranate and its derivatives for preeclampsia therapy as a basis for further basic and applied research. Purpose: To identify, evaluate, and summarize previous research evidence on the potential of pomegranate as an adjuvant therapy for preeclampsia. Method: A systematic review of literature published between January 2014 and June 2024 was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Articles were searched through Scopus, Sciencedirect, Proquest, and PubMed databases. The search used the keywords "punica granatum" OR "pomegranate" AND "preeclampsia" OR "gestational hypertension." Results: Five articles were identified, and it was found that pomegranate has potential as an adjuvant therapy for preeclampsia and may be a valuable adjunct in preeclampsia management. The rich content of antioxidant, anti-inflammatory, and vasodilatory bioactive compounds in pomegranate may contribute to risk reduction and symptom management of preeclampsia. Conclusion: Pomegranate has potential as an adjuvant therapy for preeclampsia. Suggestion: Further in vitro and in vivo studies with more robust designs, including controlled clinical trials, are needed to confirm the efficacy and safety of pomegranate. The optimal dosage and underlying mechanism of action of pomegranate in preeclampsia are also needed.   Keywords: Adjuvant Therapy; Pomegranate; Preeclampsia; Pregnant Women.   Pendahuluan: Preeklampsia menjadi penyebab utama kematian dan masalah kesehatan ibu di dunia. Preeklampsia dapat dipicu oleh peningkatan radikal bebas yang menyebabkan stres oksidatif, disfungsi endotel, dan kerusakan organ lainnya. Namun, hingga kini belum ada terapi yang mampu menghentikan preeklampsia  kecuali dengan mengakhiri kehamilan. Diperlukan scoping review untuk mengumpulkan bukti terkait penggunaan buah delima dan turunannya untuk terapi preeklampsia sebagai pijakan penelitian dasar dan terapan selanjutnya. Tujuan: Untuk mengidentifikasi, mengevaluasi, dan merangkum bukti hasil penelitian sebelumnya tentang potensi buah delima sebagai terapi adjuvan preeklampsia. Metode: Penelitian literatur sistematis yang diterbitkan antara Januari 2014 - Juni 2024 menggunakan pedoman Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA). Pencarian artikel melalui database Scopus, Sciencedirect, Proquest, dan PubMed. Pencarian artikel menggunakan kata kunci “punica granatum” OR “pomegranate” AND “preeclampsia” OR “gestational hypertension.” Hasil: 5 artikel diidentifikasi dan ditemukan bahwa buah delima memiliki potensi sebagai terapi adjuvan untuk preeklampsia dan berpotensi juga menjadi terapi tambahan yang berharga dalam manajemen preeklampsia. Buah delima yang kaya zat antioksidan, antiinflamasi, dan efek vasodilator dari senyawa bioaktif dapat berkontribusi pada pengurangan risiko dan pengelolaan gejala preeklampsia. Simpulan: Buah delima memiliki potensi sebagai terapi adjuvan untuk preeklampsia. Saran: Diperlukan untuk melakukan penelitian, baik in vitro dan in vivo lebih lanjut dengan desain yang lebih kuat, termasuk uji klinis yang terkontrol untuk mengkonfirmasi efektivitas dan keamanan penggunaan buah delima dan juga diperlukan untuk menentukan dosis yang optimal dan mekanisme kerja yang mendasari efek terapeutik buah delima pada preeklampsia.   Kata Kunci: Buah Delima; Ibu Hamil; Preeklampsia; Terapi Adjuvan.
PENERAPAN RELAKSASI DZIKIR PADA KELAS IBU HAMIL DI PRAKTIK MANDIRI BIDAN (PMB) SUBIATI DESA MIRI KABUPATEN SRAGEN Sri Wahyuni, Endang; Duwi Handayani, Juleha; Nurul Mahmudah, Irvina; Rahmawati, Ai
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 8, No 4 (2025): MARTABE : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v8i4.1489-1495

Abstract

Permasalahan psikologis selama kehamilan telah dihubungkan dengan berbagai komplikasi. Berdasarkan literatur yang ada, permasalahan atau gangguan psikologi selama hamil dapat menyebabkan pertumbuhan janin yang terhambat (fetal growth restriction), prematuritas, bayi lahir dengan berat badan rendah, serta memicu komplikasi pascapersalinan. Permasalahan psikologi juga terkait dengan munculnya hipertensi gestasional (hipertensi selama kehamilan), preeklamsia, serta diabetes dimasa hamil. Masalah psikologis, seperti kecemasan yang dialami oleh ibu hamil, tetap menjadi isu kesehatan yang serius dalam masyarakat jika tidak ditangani dengan baik. Kecemasan yang tidak dikelola dengan serius dapat berdampak negatif pada kesehatan fisik dan mental ibu serta janin dalam kandungan. Kecemasan dapat mempengaruhi hipotalamus yang menstimuli kelenjar endokrin serta mengatur kelenjar hipofise. Kondisi patologi inilah yang menyebabkan peningkatan jumlah hormon stres. Berdasarkan permasalahan tersebut, kami berinisiatif untuk melakukan pengabdian kepada masyarakat dengan memberikan asuhan kehamilan menggunakan pendekatan thibbun nabawi melalui penerapan relaksasi dzikir dalam kelas ibu hamil, yang diharapkan dapat mengurangi risiko komplikasi kehamilan dan menangani kecemasan selama masa kehamilan. Tujuan: PkM ini adalah membantu mitra untuk meningkatkan kemampuan ibu hamil dalam menjaga kesehatan fisik dan mentalnya melalui penerapan relaksasi dzikir. Metode: Pemeriksaan skor kecemasan dan dilanjutkan edukasi dengan penerapan latihan relaksasi pada kelas ibu hamil. Kegiatan PkM akan dilaksanakan di kelas ibu hamil dibawah binaan Bidan Subiati di desa Miri kabupaten Sragen. Hasil: Didapatkan jumlah skor PRAQ-R2 terendah adalah 17, tertinggi adalah 39, dan dengan skor rata-rata 27,2. Skor normal pada ibu hamil dikatakan tidak cemas adalah kurang dari total skor 23. Pada kelas ibu hamil PMB Subiati dengan skor total rata-rata 27,2, dapat diartikan bahwa ibu hamil dominan mengalami cemas. Skor paling rendah didominasi dengan ketakutan akan penampilan diri, dan skor paling tinggi didominasi kekhawatiran yang anak dikandung cacat. Simpulan: Setelah dilakukan pelatihan relaksasi dzikir untuk ibu hamil, pengetahuan dan ketrampilan melakukan relaksasi dzikir meningkat hingga 100%.
Literature Review: Terapi Komplementer Akupresur pada Titik Perikardium 6 dalam Mengatasi Mual dan Muntah pada Kehamilan Maheswara, Anisya Nur; Wahyuni, Endang Sri; Istiqomah, I; Kustiyati, Sri
Prosiding University Research Colloquium Proceeding of The 12th University Research Colloquium 2020: Mahasiswa Student Paper
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Pendahuluan: Kehamilan merupakan proses fisiologis bagi wanita, berbagai keluhan dapat terjadi pada masa kehamilan, salah satunya adalah mual dan muntah pada awal kehamilan. Hampir 50-90% wanita hamil mengalami mual pada trimester pertama. Keluhan ini merupakan merupakan hal yang fisiologis akan tetapi bila tidak segerah diatasi akan menjadi hal yang patologis sehingga akan menimbulkan komplikasi, salah satunya adalah dehidrasi serta malnutrisi. Metode yang dapat dilakukan agar tidak terjadi komplikasi tersebut adalah dengan pengobatan secara nonfarmakologis, berupa pemberian terapi akupresur titik perikardium 6 untuk menurunkan mual dan muntah pada ibu hamil. Tujuan dari literature review ini terhadap beberapa penelitian adalah untuk mengetahui apakah ada efek akupresur perikardium 6 dalam mengurangi mual dan muntah pada ibu hamil. Metode: Metode yang digunakan dalam studi ini adalah metadata analisis dengan menggunakan tinjauan literature (literature view) dengan mencari artikel yang relevan. Sumber tinjauan menggunakan media elektronik dari beberapa database antara lain Sience Direct dan Google Scholar yang dipublishkan kurun waktu tahun 2015 sampai tahun 2020. Dengan keyword, vomiting/ muntah; nausea/ mual; pregnancy/ ibu hami; acupressure/ akupresur; perikardium 6/ neiguan. Hasil: Berdasarkan hasil literature review terhadap beberapa penelitian menunjukkan adanya pengaruh pemberian teknik akupresur terhadap pengurangan mual muntah pada ibu hamil trimester I. Pembahasan: Akupresur pada titik perikardium 6 dapat menghasilkan evaluasi yang baik pada ibu yang mengalami mual dan muntah pada kategori ringan dan sedang. Terapi akupresur juga tidak perlu mengkonsumsi obat-obatan sebab dengan terapi akupresur tubuh sudah memiliki kandungan obat. Kesimpulan: Penggunaan metode acupressure pericardium 6 pada ibu hamil dalam mengurangi mual muntah menunjukkan keefektifannya.
Pengaruh Expressive Writing Therapy terhadap Self Esteem pada Pasien Skizofrenia di RSJ Dr. Radjiman Wediodiningrat Lawang-Malang Mustofa, Fathaniah Adila; Wahyuni, Endang Sri
Jurnal Terapi Wicara dan Bahasa Vol. 2 No. 2 (2024): Juni 2024
Publisher : Politeknik Kesehatan Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59686/jtwb.v2i2.99

Abstract

Abstract Background: Schizophrenia is a chronic mental illness that can affect an individual's quality of life. Individuals with schizophrenia experience a decline in self-functioning, leading to decreased social functioning that impacts self-esteem. Self-esteem is an important aspect for individuals. One non-pharmacological therapy that can be provided is cognitive psychotherapy, specifically expressive writing therapy.Objectives: This research was conducted to determine the effect of expressive writing therapy on self-esteem in schizophrenia patients at RSJ Dr. Radjiman Wediodiningrat Lawang-Malang. Methods: This research is quantitative research with a pre-experimental with a one group pretest-posttest design type. The sampling technique used was purposive sampling with a sample size of 20 people. Self-esteem was measured using the Rosenberg Self-esteem Scale (RSES) Indonesian version instrument. The data analysis technique used is the Paired Sample T-Test. Resulth: The majority of the sample were male (70%); the dominant age category of the sample was early adulthood (35%); unmarried status dominated (55%); the majority were self-employed (50%), and the educational level was high school/vocational school (50%). The average self-esteem score before intervention was 16.60, and after intervention, the average score was 20.15, indicating an increase in scores in the research sample with a difference of 3.5 points. The results of this study, measured using the Paired Sample T-Test, obtained a value of ρ < 0.05 (0.000 < 0.05). Conclusion: This research shows that there is an effect of expressive writing therapy on the self esteem of schizophrenic patients at RSJ Dr. Radjiman Wediodiningrat Lawang-Malang. Keywords : Expressive Writing Therapy, Self-Esteem, Schizophrenia
Pengaruh Senam Tai Chi terhadap Psychological Wellbeing Lansia di Posyandu Sugih Waras, Desa Ngargorejo, Kecamatan Ngemplak, Boyolali Yuniandita, Augustina Sekar; Wahyuni, Endang Sri
Jurnal Terapi Wicara dan Bahasa Vol. 2 No. 2 (2024): Juni 2024
Publisher : Politeknik Kesehatan Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59686/jtwb.v2i2.100

Abstract

Abstract Background: Elderly people experience aging which causes changes, especially psychological, experiencing empty nest syndrome, anxiety disorders, depression, loneliness, and other psychological disorders which can affect psychological well-being. Tai Chi is an exercise that can have a positive effect on psychological well-being in sufferers of various chronic diseases, can reduce symptoms of anxiety and depression, and improve quality of life. Objectives: This study aims to determine the effect of Tai Chi exercise on the psychological well-being of elderly people at Sugih Waras Integrated Health Service Post, Ngargorejo Village, Ngemplak District, Boyolali. Methods: This research is a Pre-Experimental type of quantitative research with a one group pretest-posttest design and purposive sampling technique. Psychological well-being was measured using the Indonesian version of the 18-item Ryff Psychological Well-being Scale (RPWB). Data analysis used SPSS version 25. Results: Respondents were dominated by young elderly (73.9%), female (95.7%), housewives (91.3%), individuals with no schooling/not yet finished elementary school (47.8%), widows (69.6%), and individuals living with family (69.6%). The average pre-test and post-test RPWB scores increased by 2.53. The results of the paired sample t-test hypothesis test showed a p-value of 0.000 which is less than 0.05, indicating an influence of Tai Chi exercise on the psychological well-being of the elderly at Sugih Waras Integrated Health Service Post, Ngargorejo Village, Ngemplak District, Boyolali. Conclusion: Tai Chi exercise has an effect on the psychological well-being of the elderly at Sugih Waras Integrated Health Service Post, Ngargorejo Village, Ngemplak District, Boyolali. Keywords : Tai Chi, Psychological Well-being, Elderly
Pengaruh Art Therapy (Painting) dengan Media Tote Bag terhadap Self Efficacy pada Pasien Skizofrenia di RSJD Dr. Amino Gondohutomo Provinsi Jawa Tengah Ersinidya, Ersinidya; Wahyuni, Endang Sri
Jurnal Terapi Wicara dan Bahasa Vol. 2 No. 2 (2024): Juni 2024
Publisher : Politeknik Kesehatan Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59686/jtwb.v2i2.101

Abstract

Abstract Background: Schizophrenia is a group of psychotic symptoms that affect different areas of the functioning of a person. Schizophrenics will experience impaired social functioning that is influenced by self-efficacy. Self-efficacy is a very important motivating factor to achieve success. One of the non-pharmacological therapies that can be given is art therapy (painting).  Objectives: This study was used to determine the effect of art therapy (painting) with tote bag media on self-efficacy in schizophrenia patients at RSJD Dr. Amino Gondohutomo Province of Central Java. Methods: This research is a pre-experimental quantitative research with one group pre and post-test design. The sampling technique uses purposive sampling with a population of 35 samples. Self-efficacy was measured using the Indonesian version of the General Self-Efficacy Scale (GSES) instrument. Hypothesis testing uses the Wilcoxon test. Results: The results showed that the age was predominantly late adulthood (45.7%), the majority were female (65.7%), the work history was predominantly non-working (37.1%), the majority of the sample had a marital status of being unmarried (60.0%), education level was dominated by SMA/MAN/SMK (42.9%), and the majority of the sample had an unspecified diagnosis of schizophrenia (65.7%). The average pre-test score is 21.91 and the post-test score is 29.89 with a difference of 7.98, which means there are differences in the results of the self-efficacy examination in the research sample. The results of this research were measured using the Wilcoxon test, obtaining a p-value of 0.000 (p-value <0.05). Conclusion Activities of art therapy (painting) with tote bag media influence self-efficacy in schizophrenia patients at RSJD Dr. Amino Gondohutomo Province of Central Java. It is hoped that the results of this research can become a routine therapeutic activity for schizophrenia patients at RSJD Dr. Amino Gondohutomo Province of Central Java. Keywords : Art Therapy (Painting), Self Efficacy, Schizophrenia
PRODUKTIVITAS DAN FENOTIPE LABU MADU VIOLINA (Cucurbita moschata) KETURUNAN KETIGA (F3) DENGAN TIGA SISTEM TANAM Wahyuni, Endang Sri
Agrika Vol. 18 No. 1 (2024)
Publisher : Badan Penerbitan Universitas Widyagama Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31328/ja.v18i1.5759

Abstract

  ABSTRAKTanaman labu madu merupakan persilangan antara labu kuning dan labu buttercup. Labu madu mempunyai kandungan vitamin dan mineral serta nilai ekonomi tinggi. Perakitan varietas unggul dapat dilakukan dengan menanam benih keturunan ketiga (F3). Penelitian bertujuan mengetahui produktivitas dan segregasi keturunan ketiga (F3). Penelitian dilakukan bulan Februari-Mei 2022 di DnR Hidroponik Farm Perumahan Pondok Bedadung Indah Jember. Metode penelitian menggunakan rancangan acak lengkap (RAL) dengan menanam benih labu madu F2 di tiga sistem tanam yaitu polybag/pupuk organik, konvensional/NPK (15:15:15), hidroponik NFT/AB mix. Metode deskriptif kualitatif digunakan untuk mengetahui fenotipe yang terbentuk pada keturunan ketiga di tiga sistem tanam. Hasil penelitian menunjukkan bahwa produktivitas labu madu Violina dengan sistem hidroponik adalah sebanyak 186.36 kg/100 m2, sedangkan produksi pada sistem tanam yang organik dan konvensional berturut-turut sebanyak 104.16 dan 86.59 kg/100 m2. Fenotipe labu madu F1 semuanya seragam. Labu madu F2 yang bersegregasi menghasilkan 6 fenotipe, sementara pada keturunan ketiga (F3) terbentuk 15 fenotipe. ABSTRACTThe honey gourd plant is a cross between a pumpkin and a buttercup pumpkin. Honey pumpkin contains vitamins and minerals as well as high economic value. The development of superior varieties can be done by planting seeds of the third generation (F3). The research aims to determine the productivity and segregation of the third generation (F3). The research was conducted in February-May 2022 at the DnR Hydroponic Farm, Pondok Bedadung Indah Jember Housing. The research method used a completely randomized design (CRD) by planting F2 honey pumpkin seeds in three planting systems, namely polybag/organic fertilizer, conventional/NPK (15:15:15), hydroponic NFT/AB mix. Qualitative descriptive methods were used to determine the phenotype formed in the third generation in three planting systems. The research results showed that the productivity of Violina honey pumpkin using the hydroponic system was 186.36 kg/100 m2, while production using the organic and conventional planting systems was 104.16 and 86.59 kg/100 m2 respectively. The phenotypes of F1 honey pumpkins are all uniform. Segregating F2 honey gourds produced 6 phenotypes, while in the third generation (F3) 15 phenotypes were formed.
PENGARUH GROWTH OPPORTUNITY, NET WORKING CAPITAL, FIRM SIZE, PROFITABILITAS DAN CASH FLOW TERHADAP CASH HOLDING PERUSAHAAN NON CONSUMER CYCLICAL YANG TERDAFTAR DI BEI Wijayanti, Esa; Cahyo, Heru; Wahyuni, Endang Sri
JURNAL LENTERA AKUNTANSI Vol. 8 No. 2 (2023): JURNAL LENTERA AKUNTANSI, NOVEMBER 2023
Publisher : POLITEKNIK LP3I JAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34127/jrakt.v8i2.1090

Abstract

This study aims to analyze the effect of growth opportunity, net working capital, firm size, profitability, and cash flow on cash holding in non-cyclical consumer companies listed on the Indonesia Stock Exchange during the period 2018 to 2021. This research is a quantitative study with the sampling technique is purposive sampling technique and the research method used is panel data regression analysis. The results of data analysis show that growth opportunity, net working capital has a positive and insignificant effect on cash holding while firm size, and profitability have a negative and insignificant effect on cash holding. Meanwhile, cash flow has a significant positive effect on cash holding, in this case strong cash flow indicates that the company is able to generate consistent income from its operational activities. With sufficient cash flow, companies can maintain a level of cash reserves to maintain liquidity in emergency or uncertain situations. If cash inflows are greater than cash outflows, then the company will have a surplus of cash funds that can be held in reserve or used for other purposes. Therefore, the company must pay close attention to the cash inflow and outflow cycle. This research provides important insights for company management in making decisions regarding cash allocation and risk management strategies. Keyword: Growth Opportunity, Net Working Capital, Firm Size, Profitabilitas, Cash Flow, Cash Holding