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Comparative Effectiveness of Antidiabetic Therapies on Clinical Outcomes in Type 2 Diabetes Mellitus Outpatients Tandah, Muhamad Rinaldhi; Diana, Khusnul; Hidayat, Chairunisah; Ambianti, Nurul
Journal of Health and Nutrition Research Vol. 4 No. 2 (2025)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jhnresearch.v4i2.481

Abstract

This study used observational analysis with retrospective data collection. A total of 303 outpatients with were included in this study. The research instrument used was secondary from medical record data and examination results of Fasting Plasma Glucose (FPG) and 2-hour plasma glucose (2-h PG) values when the patient first visited and the fourth month after the first visit. The patients' therapy is regarded as effective if the FPG test results range from 80-130 mg/dL and the 2-h PG test value is <180 mg/dL in the fourth month. In patients aged >60 years, it is said to be effective if the results of the FPG examination are around ≤ 180 mg/dL and the 2-h PG examination value is ≤200 mg/dL. Data were analyzed using Kruskal-Wallis analysis. Oral antidiabetics metformin and glimepiride had differences in observed effectiveness (p=0.000) < 0.05 for FPG and 2-h PG examinations in outpatients with type 2 diabetes mellitus. The type of oral antidiabetic glimepiride had differences in observed effectiveness (p=0.002) < 0.05 in the FPG examination and (p=0.006) < 0.05 in the 2-h PG examination. The oral antidiabetic drug groups metformin and glimepiride had differences in observed therapeutic effectiveness in outpatients with T2DM, while the insulin group and the combination group did not have differences in therapeutic effectiveness in T2DM patients.
Evaluasi Sistem Informasi Manajemen Rumah Sakit Menggunakan end User Computing Satisfaction di RSUD Madani Palu: Evaluation of Hospital Management Information System Using end User Computing Satisfaction at Madani Rsud Palu Ririen Hardani; Khusnul Diana; Taufik, Afinka Eka Hijrawati
Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Vol. 7 No. 3: MARCH 2024 - Media Publikasi Promosi Kesehatan Indonesia (MPPKI)
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/mppki.v7i3.4585

Abstract

Latar Belakang: Sistem Informasi Manajemen Rumah Sakit (SIMRS) digunakan dalam mengakses sistem yang menangani seluruh proses manajemen yang terdiri atas pelayanan diagnosa serta tindakan kepada pasien, medical record, apotek, gudang farmasi, dan SIMRS juga mencakup sistem komputerasasi. Tujuan: Penelitian ini bertujuan untuk mengukur tingkat kepuasan pengguna Sistem Informasi Manajemen Rumah Sakit (SIMRS) berdasarkan aspek isi, keakuratan, tampilan, ketepatan waktu, serta kemudahan dalam pengguna. Metode: Penelitian yang digunakan adalah End-User Computing Satisfaction (EUCS) dengan melakukan observasi (non-eksperimen) desain cross sectional. Pengumpulan data dilakukan dengan menggunakan lembar kuesioner yang dibagikan kepada 112 sampel yang merupakan pegawai RSUD Madani. Hasil: Penelitian menunjukkan bahwa tingkat kepuasan untuk seluruh variabel EUCS berada pada kategori puas yang menandakan bahwa pengguna sudah merasa puas dengan penggunaan SIMRS di RSUD Madani sehingga perlu dipertahankan.
Analisis Faktor yang Mempengaruhi Konsumen dalam Membeli Obat Tradisional di Kota Luwuk Faradilla, Nadila; Diana, Khusnul; Tandah, Muhamad Rinaldhi
JURNAL FARMASI GALENIKA Vol 9 No 2 (2022): Jurnal Farmasi Galenika Vol 9 No 2
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70410/jfg.v9i2.201

Abstract

Obat tradisional merupakan warisan budaya bangsa yang dimanfaatkan di Indonesia sebagai pengobatan alternatif. Penggunaan berbagai produk obat tradisional yang dikonsumsi masyarakat tidak diimbangi dengan kesadaran dan pengetahuan mengenai khasiatnya sehingga faktor yang mempengaruhi masyarakat dalam membeli obat tradisional masih sangat kurang diketahui. Penelitian ini bertujuan untuk mengetahui faktor yang mempengaruhi pembelian obat tradisional dan hubungan antara karakteristik demografi dengan tempat pembelian obat tradisional di Kota Luwuk. Jenis penelitian berupa observasional dengan pengambilan data secara cross-sectional pada masyarakat Kota Luwuk, teknik pengambilan sampel secara purposive sampling menggunakan instrumen kuesioner yang berisi 25 pertanyaan dengan media google form. Hasil penelitian faktor yang berpengaruh terhadap pembelian obat tradisional dengan analisis uji Kruskal-Wallis didapatkan nilai sig. < 0,05 pada faktor psikologis (0,319); sosial (0,061); budaya (0,039); dan pribadi (0,055). Hubungan antara karakteristik demografi dengan tempat pembelian obat tradisional menggunakan uji Chi-square didapatkan nilai sig. < 0,05 pada jenis kelamin (0,021); usia (0,165); pendidikan terakhir (0,001); pekerjaan (0,000); dan pengeluaran per bulan (0,000). Faktor yang mempengaruhi pembelian obat tradisional adalah faktor budaya dan kelompok usia yang tidak mempengaruhi pembelian obat tradisional dengan karakteristik responden.
EDUKASI OBAT RUSAK DAN KEDALUARSA PADA MASYARAKAT DESA TOSALE, KECAMATAN BANAWA SELATAN, KABUPATEN DONGGALA diana, khusnul; Rinaldhi Tandah, Muhamad; Ambianti, Nurul; Fadhilah Zainal, Setiawati
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 1 No. 1 (2022): Oktober 2022
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2022.v1.i1.16099

Abstract

Using damaged and expired drugs in the community can be a problem for health. Using medicines that have been damaged or drugs that have expired can be fatal, ranging from poisoning, and disability, to causing death. Many factors can cause damaged and expired drugs, both occurring in health facilities (such as pharmacies, hospitals, health centers, and distributors) or the storage of drug users in this case in the community. People as users of medicinal products sometimes do not know how the physical characteristics and signs of drugs are damaged and medicines that have expired. This community service activity was carried out in the Tosale Village area of ​​Donggala to assist the local community in knowing and recognizing drugs that were damaged or expired. This activity is carried out using lecture and discussion methods around recognizing the characteristics and signs of damaged and expired drugs, how to prevent the occurrence of damaged and expired drugs and how to store medicines to avoid damage. Evaluation of activities by giving short questions to participants about the material that has been given to identifying damaged and expired drugs. Active participants who answered correctly were given the appreciation in the form of mementos from the service team. This activity was completed by the target number of participants and the time given by the Tosale Village Head.
EDUKASI PENGELOLAAN OBAT RUSAK DAN KEDALUWARSA MENGGUNAKAN MEDIA LEAFLET DI DESA UENUNI, KECAMATAN PALOLO, KABUPATEN SIGI: Education on Management of Damaged and Expired Medicines Using Leaflet Media Diana, Khusnul; Ambianti, Nurul; Tandah, Muhamad Rinaldhi; Zainal, Setiawati Fadhilah
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 2 No. 1 (2023): Oktober 2023
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2023.v2.i1.16660

Abstract

Masyarakat memperoleh obat dari apotek atau fasilitas kesehatan akan menyimpan obat-obatannya di rumah untuk berbagai keperluan termasuk penggunaan darurat dan penyakit akut atau kronis. Kebanyakan obat-obatan yang di simpan di rumah akhirnya tidak digunakan dan menjadi kedaluwarsa. Kurangnya pengetahuan dan informasi terkait cara mengelola obat rusak dan obat kedaluwarsa mengakibatkan masyarakat melakukan praktik pembuangan obat yang tidak digunakan langsung ke tempat sampah umum. Hal ini akan menyebabkan permasalahan yang cukup besar dilingkungan masyarakat. Kegiatan pengabdian kepada masyarakat dilakukan di Desa Unenui Kecamatan Palolo Kabupaten Sigi. Secara tipologi dan geologi desa ini terletak di pegunungan, sehingga akses sarana fasilitas kesehatan dan tenaga kesehatan masih terbatas. Pengabdian ini bertujuan untuk membantu masyarakat dalam memahami dan meningkatkan pengetahuan terkait pengelolaan obat rusak dan kedaluwarsa. Kegiatan ini dilakukan dengan metode edukasi melalui upaya pemberian informasi dan pembagian leaflet tentang definisi obat rusak dan kedaluwarsa, penyebab dan ciri-ciri obat rusak, cara pengecekkan obat kedaluwarsa, serta cara memusnahkan obat rusak dan kedaluwarsa. Evaluasi kegiatan dengan memberikan pertanyaan singkat kepada peserta tentang isi materi pada leaflet. Kegiatan ini selesai dilaksanakan sesuai dengan target jumlah peserta dan waktu yang diberikan oleh Kepala Desa Uenuni.
Pelatihan Pengelolaan dan Pemusnahan Limbah Obat Rusak dan Kadaluarsa di Desa Kotapulu Kabupaten Sigi Tandah, Muhamad Rinaldhi; Diana, Khusnul; Adisaputra, Arya Dibyo; Hardani, Ririen
JURNAL PENGABDIAN FARMASI DAN SAINS Vol. 2 No. 2 (2024): April 2024
Publisher : Jurusan Farmasi FMIPA Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/jpsf.2024.v2.i2.17096

Abstract

The widespread circulation of illegal drugs poses a serious threat to society as it can have negative impacts on health. In 2019, BPOM Palu confiscated illegal drugs and cosmetics from various areas in Central Sulawesi. A law enforcement operation in Sigi Regency on September 23, 2020, together with the Central Sulawesi Regional Police, successfully seized Class G prescription drugs, traditional medicines, and illegal cosmetics (BPOM Palu, 2022). The main cause of illegal drug circulation is the improper reuse of household drug waste, exploited by irresponsible parties. The use of illegal drugs, which may consist of counterfeit, damaged, or expired items, can endanger health and even lives. One crucial step to prevent this is by managing drug waste properly. Since 2019, BPOM has been conducting awareness campaigns such as "Beware of Illegal Drugs, Dispose of Drug Waste Properly" to educate the public on proper drug disposal (BPOM, 2019). Many people still don't understand the correct way to manage and dispose of expired drugs. Most of them throw these drugs into the trash, potentially fueling illegal drug reuse by irresponsible parties. Training and awareness efforts, such as those conducted in Kotapulu Village, Dolo District, Sigi Regency, are highly relevant. With better knowledge of proper drug management and disposal, it is hoped that communities can independently address drug waste issues, ultimately reducing the circulation of illegal drugs in the region. These activities are crucial for educating the public about the dangers of illegal drugs and the importance of proper drug waste management. The goal is to help reduce the circulation of illegal drugs, especially in Central Sulawesi, thereby safeguarding the overall health and safety of the community.
STUDI LITERATURE INVENTARISASI TUMBUHAN OBAT KHAS KABUPATEN PASANGKAYU Jamal, Jamaluddin; Arifin, Pitriani; Diana, Khusnul; Anjelita, Anjelita; Parumpu, Firdawati A
Preventif : Jurnal Kesehatan Masyarakat Vol. 14 No. 1 (2023): Volume 14 No. 1 (2023)
Publisher : Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/preventif.v14i1.640

Abstract

Inventory of medical plants is an activity of collecting and compiling data and facts regarding natural resources for resource management planning and can be used as database to reveal potential and information as a reference for introducing plant species in the research area. This study aims to make an inventory of what plants are efficacious as drugs, and to find out their benefits based on preclinical and clinical trials. This type of research is a descriptive study using the SLR (Systematic Literature Review) method with a sample of 21 literatures. The results of the library show that there are 68 plants that are used empirically by the Kabupaten Pasangkayu community. Some of these plants have gone through preclinical and clinical trials. Plants that are efficacious as traditional medicine vary, such as antidiabetic, antihypertensive and so on empirically amounted to 68 plants which from 4 different regions that was pasangkayu 57 plants, mamuju 5 plants, dapurang 3 plants and baras 3 plants.
Quality of Life among Hemodialysis Patients with or Without Diabetes Mellitus at Undata Hospital, Palu: Kualitas Hidup Pasien Yang Menjalani Hemodialisa Dengan Komplikasi dan Tanpa Komplikasi Diabetes Melitus Di RSUD Undata Palu Diana, Khusnul; Kristiono, Oviani; Tandah, Muhamad Rinaldhi
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 11 No. 2 (2025): October 2025
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2025.v11.i2.17893

Abstract

Background: Hemodialysis is a renal replacement therapy for patients with end-stage chronic kidney disease (CKD). Diabetes mellitus is a leading cause of CKD. Hemodialysis can affect health-related quality of life (HRQoL), as biological and psychological domains and daily life may vary by age, sex, education, and type of treatment received by patients.Objectives: To assess HRQoL among hemodialysis patients at Undata Hospital, Palu, according to age, sex, comorbidities, years of undergoing dialysis, and education level.Methods: An observational study was conducted using convenience sampling. Data were collected through structured questionnaires and medical records. The study included a total of 88 participants who met the inclusion and exclusion criteria. Instruments used included demographic characteristics, social functioning, mental and physical well-being, and overall quality of life descriptions.Results: Most participants were male (55.7%), aged 31–56 years (68.2%), and undergoing HD twice weekly (93.2%). The HRQoL domains were moderate. Forty patients (45.5%) had no diabetes and 48 had diabetes mellitus. Mean HRQoL scores were 46.60 for patients without DM and 45.91 for patients with DM. There was no significant difference in HRQoL based on age (p=0.104), dialysis duration (p=0.015), or educational background (p=0.973). Only comorbidity was associated (p=0.750).Conclusion: Hemodialysis patients with diabetes mellitus experience lower HRQoL than those without. Age, dialysis duration, and education level are additional determinants of HRQoL in this population.
KEGAGALAN PENGENDALIAN DIABETES MELLITUS TIPE II DITINJAU DARI FAKTOR PREDISPOSISI Khusnul Diana; Amalia Purnamasari Zainal; Setaiawati Fadhilah Zainal; Muhammad Rinaldhi Tandah; Dhea Puspita; Nurul Ambianti
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 10 No. 2 (2024): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v10i2.886

Abstract

Failure to control type II diabetes mellitus (DM) has a serious impact on the quality of life and health of DM patients. One of the factors that can influence the failure to control DM is predisposing factors. This study aims to determine predisposing factors including gender, education level, age, smoking, occupation, sports activities, long-suffering, knowledge, and behavior that influence failure to control type II DM. The research method used was descriptive analysis with cross-sectional data collection. This research used a purposive sampling technique and the patients used were 179 respondents. Data was collected using the Diabetes Knowledge Questionnaire (DKQ-24) questionnaire and the Self-Management Diabetes Mellitus (SMDM) questionnaire instrument. The data analysis used is bivariate and multivariate. The results of the bivariate analysis show that the variables that influence the failure to control Type II DM are the length of suffering (p = 0.000), behavior (p = 0.004), sports activities (p = 0.029), and work (p = 0.020). The results of the multivariate analysis of the dominant factors influencing failure to control type II DM are long-suffering with a value of OR = 6.956, behavior with a value of OR = 4.156, knowledge with a value of OR = 2.947, sports activities with a value of OR = 0.690, so it can be concluded that the variable long-suffering is The main factor in the failure to control type II DM because it can increase the risk of complications such as pancreatic cell damage and insulin resistance.