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All Journal Jurnal Keperawatan Padjadjaran JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Majalah Biomorfologi (Biomorphology Journal) Jurnal Pengabdian kepada Masyarakat Nusantara AKSONA Sewagati
Kusuma Eko Purwantari
Department Of Anatomy, Histology, And Pharmacology, Faculty Of Medicine, Universitas Airlangga/Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Effectiveness of Medication, Surgery, and Combination Therapy to Decrease Intraocular Pressure on Glaucoma Outpatient at Outpatient Ophthalmic Clinic Dr. Soetomo General Hospital Surabaya in January – December 2017 Muhammad Bagas Pratista; Nurwasis Nurwasis; Kusuma Eko Purwantari; Indri Wahyuni
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 13 No. 2 (2022): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V13I22022.67-72

Abstract

Highlights:1. Combination of medication and surgery on glaucoma had the least post-therapy intraocular pressure.2. There was no significant difference in the efficacy of drugs, surgeries, and combination of both therapies for glaucoma intraocular pressure reduction. AbstractIntroduction: Glaucoma leads to blindness in its end stage. Quality of life drops as visual field loss as progressive optic nerve damage since high intraocular pressure elevation. Glaucoma treatment focused on aqueous humor regulation, thus the intraocular pressure is maintained at normal.Methods: This was a retrospective analytical study using secondary data gathered from medical records as total sampling data. The sample was determined by the purposive non-probability technique. The mean of intraocular pressure after therapies was defined as the dependent variable while the independent variable was the type of therapy.Results: Combined therapy (16.00 ± 6.77 mmHg) had the least post-therapy intraocular pressure. The statistical test indicated no significant difference in the effectiveness of medication, surgery, and combination therapy for glaucoma intraocular pressure reduction.Conclusion: There was no prominent difference in the efficacy of drugs, surgeries, and combined therapies for glaucoma intraocular pressure reduction.
A Rare Case of Dural Tail Sign in the Patient with Glioblastoma Multiforme: A Case Report Risdiansyah Risdiansyah; Kusuma Eko Purwantari; Viskasari P Kalanjati; Rahadian I Susilo
AKSONA Vol. 3 No. 2 (2023): JULY 2023
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/aksona.v3i2.46639

Abstract

Highlight: A dural tail sign was found in T1W1-MR-images with contrast of a patient with glioblastoma multiforme. Glioblastoma multiforme as a grade IV malignancy of the astrocytes' glioma, the dura mater can be infiltrated and shown as DTS, although rarely reported.   ABSTRACT Introduction: The dural tail sign (DTS), which is rarely seen in patients with glioblastoma multiforme (GBM), is reported here. This sign is generally found as a manifestation of meningioma due to the reactive changes of the tumor’s invasion. Case: A 61-year-old Javanese man presented with a gradually worsening headache two months prior to hospital admission. He also suffered from paralysis of his right extremities. His complete blood tests and clinical chemistry were within normal limits. A head CT scan showed a large mass near the convexity of the brain in the left parietal lobe, along with edema and a shift of the midline structures to the right. This was confirmed on the T1W1 MR images with contrast, where DTS was clearly shown. Following surgical resection and tumor excision, histopathology analysis revealed GBM with malignant cell infiltration to the dura in the vicinity of the neoplasm. Conclusion: Here we showed a DTS in GBM as a malignant infiltration marker into the dura    
Mental health and decision-making participation of adolescent orphans: A pilot study Annette d'Arqom; Farhan Nurdiansyah; Danti Nur Indiastuti; Mhd Zamal Nasution; Nurmawati Fatimah; Sri Purwaningsih; Yuani Setiawati; Kusuma Eko Purwantari
Jurnal Keperawatan Padjadjaran Vol. 11 No. 3 (2023): Jurnal Keperawatan Padjadjaran
Publisher : Faculty of Nursing Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkp.v11i3.2358

Abstract

Background: Mental health has been brought to attention lately, with the increase of mental health problems during adolescence. In Indonesia, it is reported that one-third of adolescents develop mental health disorders. Childhood grief, separation from the family, child labor, or abuse affect the orphans’ mental health, including their decision-making participation. Purpose: As a pilot study, this study would like to investigate the mental health conditions and decision-making participation among orphans in one orphanage in Mojokerto district, East Java, Indonesia.Methods: This cross-sectional study utilizes the Depression Anxiety Scale Youth version (DASS-Y) and Child and Adolescent Participation in Decision Making Questionnaire (CAP-DMQ). Thirty-five adolescent orphans of one orphanage in Mojokerto were recruited using convenience sampling. The frequency of respondents’ mental health and decision-making participation were measured, and the mean differences between each group of sociodemographic factors were measured using the Mann-Whitney U test or the Kruskal Wallis test. Association between mental health and decision-making participation was calculated using Chi-square test.Results: The results show that 40% of respondents were categorized as having mild mental health problems, including depression, anxiety, and stress. Mental health problems are mostly found in males (22.90%) and elementary school (20%). The participation of the orphans in decision-making is considered good, with a median of 25.5. The bivariate analysis concludes the association between anxiety, age, grade, and decision-making participation (p= 0.024, p= 0.029, p=0.029, respectively).Conclusion: Taken together, attention to orphans, especially adolescents, and their problems are necessary to reduce the health discrepancies within these vulnerable groups. Broader respondents are needed to understand the complete picture of mental health conditions among Indonesian adolescent orphans, including late adolescents.
EXPOSURE TO GOAT BILE FOR 28-DAYS CAUSES HEPATOCYTE INJURY: A HISTOPATHOLOGICAL STUDY Rizki Isnantono Prabowo; Nurina Hasanatuludhhiyah; Nily Sulistyorini; Kusuma Eko Purwantari
Majalah Biomorfologi Vol. 32 No. 2 (2022): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v32i2.2022.65-72

Abstract

Highlights: 1. Bile consumption, especially goat bile, is believed to have therapeutic effects even though it contains harmful ingredients that can cause toxic effects on the liver2. The administration of goat bile for 28 days had a toxic effect on the liver of the mice based on histopathological findings Abstract: Background: Bile consumption by Indonesians is believed to have therapeutic effects, especially goat bile. Goat bile is thought to contain harmful ingredients that can cause toxic effects on the liver. However, the 28-days oral toxicity study of goat bile has not been performed. Objective: To analyze the hepatotoxic effect of subchronic administration of goat bile on the liver of mice (Mus musculus). Material and Method: This was an experimental research with a post-test-only control group design. The samples used were 32 Balb/C mice (Mus musculus), which were grouped into 4 groups. The samples were administered with goat bile orally (3.2, 6.4, or 12.8 mL/kg/day) for 28 days. The liver was taken for histopathological examination and the hepatocytes injury score was performed. The scoring results were analyzed using Kruskal-Wallis, Mann-Whitney, and Spearman correlation tests (p<0.05). Result: Goat bile administration was associated with hepatocyte injury (p= 0.004). Groups with goat bile administration of 6.4 and 12.8 mL/kg/day had significant differences with the control group (p= .015 and .029 respectively) and the 3.2 mL/kg/day administered group (p= 0.006 and 0.009 respectively). Moreover, the increased administration of goat bile had a positive correlation with the level of hepatocyte injury (p= 0.004 and r_s= 0.504) Conclusion: Goat bile administration for 28 days had a significant toxic effect on the liver of mice at a dose of 6.4 mL/kg/day.
POTENTIAL OF RED OKRA (Abelmoschus esculentus (L.) Moench) ETHANOL EXTRACT TO PROTECT AGAINST 7, 12-DIMETHYLBENZ[A]ANTHRACENE-INDUCED DAMAGE IN RAT'S (Rattus norvegicus) Liver Lukiteswari Dyah Tri Hapsari; Kusuma Eko Purwantari; Indri Safitri Mukono; Sri Puji Astuti Wahyuningsih; Nadyatul Ilma Indah Savira
Majalah Biomorfologi Vol. 34 No. 1 (2024): MAJALAH BIOMORFOLOGI
Publisher : Universitas Airlangga, Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mbiom.v34i1.2024.10-18

Abstract

Highlights: Red okra pods have a potential antioxidant to protect against DMBA-induced damage in a rat's liver. The liver protection with ROE decreased reversible and irreversible cellular damage from 51.8% to 35%, 27.3%, and 18.9%.   Abstract Background: Okra (Abelmonchus esculentus (L.) Moench) is a plant that has potential for humans and health because it contains high antioxidants such as polyphenols. Objective: This study aimed to analyze the red okra pods' ethanol extract (ROE) antioxidant potential to protect rat (Rattus norvegicus L.) liver against damage by induction of 7, 12-dimethyl-benz[a]anthracene (DMBA). Material and Method: The material used was various doses of red okra pods with ethanol as solvent. Twenty-five female rats (4 weeks, body weight 140”150 g) were divided into five groups: negative control (receiving a single dose of 0.5 mL corn oil as DMBA solvent), positive control (receiving a single dose induction of DMBA 80 mg/kg BW dissolved in 0.5 mL corn oil), and treatment groups 1, 2, 3 (receiving a single dose of DMBA 80 mg/kg BW dissolved in 0.5 mL corn oil and ROE of 50, 100, and 200 mg/kg BW, respectively, daily for 35 days). On day 36, the livers were removed and prepared for histopathological observation using hematoxylin-eosin staining. The method of histopathological score was determined using an ordinal score. Result: The data were analyzed statistically (p>0.05). All ROE doses showed a significant decrease in the histopathological score of rats' liver damage caused by DMBA-induced. The liver protection with ROE reduced the percentages of reversible and irreversible cellular damage from 51.8% to 35%, 27.3%, and 18.9%, respectively. Conclusion: The red okra pod ethanol extract can protect against DMBA-induced liver damage in rats.
Pemberdayaan Remaja dalam Pencegahan Cyberbullying untuk Mencapai Kesehatan Mental di MAN Kota Mojokerto Prasetiowati, Lucky; Yuliawati, Tri Hartini; Purwantari, Kusuma Eko; Sakina, Sakina; Syulthoni, Zain Budi; Qorib, Muhammad Fathul; Sari, Dewi Ratna
Sewagati Vol 9 No 2 (2025)
Publisher : Pusat Publikasi ITS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12962/j26139960.v9i2.2765

Abstract

Keberadaan media sosial di kalangan remaja telah menjadi gaya hidup. Media sosial memberikan dampak positif dan negatif bagi penggunanya, Salah satu dampak negatif yaitu munculnya fenomena cyberbullying. Cyberbullying mengacu pada perilaku perundungan, seperti penghinaan, pelecehan, pencemaran nama baik, dan tindakan serupa yang dilakukan secara daring dan dapat berlangsung terus-menerus. Kurangnya pengawasan terhadap penggunaan media sosial oleh remaja berkontribusi pada keberlanjutan tindakan ini, sehingga menimbulkan dampak psikologis yang signifikan pada korban. Program pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan remaja mengenai cyberbullying guna memberdayakan peran mereka dalam kegiatan pencegahan baik di lingkungan sekolah maupun masyarakat. Metode yang digunakan adalah edukasi kesehatan mental dan penugasan karya video edukasi. Kegiatan edukasi dilaksanakan di MAN Kota Mojokerto secara luring dengan sasaran 100 siswa – siswi. Sebelum dan sesudah edukasi, peserta diminta mengisi kuesioner pre-test dan post-test. Kemudian dilanjutkan dengan lomba video edukasi satu bulan setelah edukasi dengan tema “stop cyberbullying”. Hasil kegiatan didapatkan bahwa pemberian edukasi kesehatan mental berpengaruh pada peningkatan pengetahuan peserta mengenai cyberbullying secara signifikan (p<0,001). Setelah mendapatkan edukasi, siswa berperan membuat media promosi kesehatan yang berupa video edukasi untuk disebarkan media sosial guna mencegah kejadian cyberbullying untuk mencapai kesehatan mental remaja yang optimal
Pemberdayaan Masyarakat dalam Pemulihan Dampak Fisiologis dan Psikologis Pasca Bencana di Desa Kertowono Kecamatan Gucialit Kabupaten Lumajang Purwantari, Kusuma Eko; Prasetiowati, Lucky; Yuliawati, Tri Hartini; Sakina, Sakina; Susanto , Joni; Qorib, Muhammad Fathul; Fithriyah, Izzatul; Rimba, Efendi; Vinda, Igha
Jurnal Pengabdian kepada Masyarakat Nusantara Vol. 6 No. 1 (2025): Jurnal Pengabdian kepada Masyarakat Nusantara Edisi Januari - Maret
Publisher : Lembaga Dongan Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Desa Kertowono, Kecamatan Gucialit, Lumajang merupakan daerah terdampak bencana erupsi Gunung Semeru. Dampak fisik dan psikis dapat timbul pasca bencana pada masyarakat setempat. Kondisi ini diperburuk dengan akses transportasi yang terbatas sehingga warga mengalami kesulitan dalam mengakses pusat pelayanan kesehatan. Akibatnya terjadi peningkatan resiko penyakit menular (infeksi saluran napas akut dan diare) dan ada kecenderungan peningkatan komplikasi penyakit kronis. Selain itu masalah psikologis seperti trauma, depresi, perasaan tidak berdaya dan lainnya juga dapat ditemukan pasca bencana. Penanganan pasca bencana tidak hanya menjadi tanggung jawab pemerinta tetapi semua pihak dapat bergerak membantu sesuai dengan kemampuan dan kompetensinya. Oleh karena itu kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pemberdayaan masyarakat dalam pemulihan dampak fisiologi dan psikologis di wilayah pasca bencana. Kegiatan pengabdian ini terdiri dari penyuluhan tentang perilaku hidup bersih dan sehat (PHBS) dan pengukuran status gizi pada anak sekolah, penyuluhan kesehatan mental pasca bencana dan pemeriksaan kesehatan bagi warga. Pemberian materi penyuluhan memberikan pengetahuan dan pemahaman terkait PHBS dan kesehatan mental merupakan kegiatan yang efektif dan diharapkan mampu memicu perubahan perilaku mulai dari diri sendiri dan keluarga sebagai lingkungan terdekat. Hasil pemeriksaan kesehatan didapatkan bahwa sebagian besar memiliki kadar glukosa darah yang masuk dalam kategori prediabetik, sedangkan kadar asam urat dan kolesterol normal.
Co-Authors Annette d’Arqom, Annette Dewi Ratna Sari Dewi Ratna Sari Farhan Nurdiansyah Fatimah, Nurmawati Indiastuti, Danti Nur Indri Safitri Mukono, Indri Safitri Indri Wahyuni Izzatul Fithriyah Lucky Prasetiowati Lukiteswari Dyah Tri Hapsari Mhd Zamal Nasution Muhammad Bagas Pratista Nadyatul Ilma Indah Savira Ni Wajan Tirthaningsih Nily Sulistyorini Nurina Hasanatuludhhiyah Nurwasis Nurwasis Qorib, Muhammad Fathul Rahadian I Susilo Rimba, Efendi Rimbun Rimbun Risdiansyah Risdiansyah Rizki Isnantono Prabowo Sakina Sakina, Sakina Sri Puji Astuti Wahyuningsih Sri Purwaningsih Susanto , Joni Syulthoni, Zain Budi Tri Hartini Yuliawati Vinda, Igha Viskasari P. Kalanjati Yuani Setiawati Yuliawati, Tri Hartini