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All Journal Jurnal Penelitian Pendidikan IPA (JPPIPA) Adi Widya : Jurnal Pengabdian Masyarakat Jurnal Ilmiah Jophus: Journal of Pharmacy UMUS Jurnal ABDIMAS-HIP Pengabdian Kepada Masyarakat Jurnal Farmasi Sains dan Praktis Indonesian Journal of Innovation Multidisipliner Research Aspirasi : Publikasi Hasil Pengabdian dan Kegiatan Masyarakat Jurnal Tumbuhan Obat Indonesia Indonesian Journal of Innovation Multidisipliner Research Jurnal Ilmiah Nusantara
Ajeng Puspo Aji
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Physics Public Health Social Sciences Other

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Pengabdian Donor Darah pada Masyarakat Sidanegara Cilacap: Blood Donation Service to The Sidanegara Cilacap Community Issusilaningtyas, Elisa; Pertiwi, Yuniariana; Rochmah, Nikmah Nuur; Aji, Ajeng Puspo; Yulianto, Asep Nurrahman; Yogawati, Nursanti Dwi; Faoziyah, Anita Ratna; Wardani, Tri Kusuma
Jurnal ABDIMAS-HIP Pengabdian Kepada Masyarakat Vol. 5 No. 2 (2024): Jurnal ABDIMAS-HIP Pengabdian Kepada Masyarakat
Publisher : LPPM Akbid Harapan Ibu Pekalongan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37402/abdimaship.vol5.iss2.309

Abstract

The scarcity of blood is assumed to be caused by a lack of public knowledge about blood donation. Donor health advantages can minimize the danger of cancer, help with weight loss, make the body psychologically better and prolong life, reduce the risk of heart and blood vessel disease, and detect major disorders. Aside from carrying out the Tri Dharma of Higher Education, community service activities seek to encourage local residents to donate blood for the safety of others, hence raising people's desire and willingness to contribute. PMI Cilacap supports this program by sending numerous medical personnel to perform blood draws. The service team distributed information about the benefits of blood donation during this activity. There were 62 registered blood donors, with 43 (69.35%) passing the health check and donating blood, and 19 (30.65%) failing (not passing) the health check and so unable to donate blood.
Subchronic Toxicity Test of Burdock Root (Arctium Lappa L.) Nanoemulsion Based on Histopathology on The Albino Rat Rattus noverticus (Wistar strain): Uji Toksisitas Subkronik Nanoemulsi Akar Burdock (Arctium Lappa L.) Berdasarkan Histopatologi pada Tikus Albino Rattus noverticus (strain Wistar) Faizal, Imam Agus; Puspodewi, Dini; Aji, Ajeng Puspo
Indonesian Journal of Innovation Multidisipliner Research Vol. 2 No. 2 (2024): June
Publisher : Institute of Advanced Knowledge and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69693/ijim.v2i2.140

Abstract

Tanaman burdock (Arctium lappa L.) merupakan tanaman herbal yang berkhasiat sebagai penambah darah (hemoglobin dan hematokrit) pada penderita anemia defisiensi besi. Sebanyak 15 ekor tikus (Rattus norvegicus) strain Wistar, jantan dan betina dibagi menjadi 3 kelompok secara random sampling yaitu Kelompok 1 Kontrol negatif (KN) tidak diberi A. lappa L. nanoemulsion. Kelompok Dosis 1 (KD1) diberi A. lappa L. nanoemulsion dengan dosis 150 mg/kgBB/hari. Kelompok Dosis 2 (KD2) diberikan A. lappa L. nanoemulsion dengan dosis 450 mg/kgBB/hari (selama 14 hari dimulai hari ke 8). Indikator penelitian ini dilihat kadar pemeriksaan biokimia kadar darah. Organ hati dan ginjal dinilai menggunakan Hematoxylin-Eosin (HE). Hasil pemeriksaan biokimia darah relatif normal. Sedangkan pewarnaan HE pada kelompok KD1 dan KD2 terjadi perubahan pada sel organ ginjal dan hati, menunjukkan bahwa sediaan nanoemulsi akar burdock bersifat toksik, namun terdapat faktor pengganggu yaitu ditemukan cacing parasit Taenia taeniaeformis, sehingga interpretasi hasilnya terganggu.
Peningkatan Aktivitas Afrodisiak Mikroemulsi Icariin, Ekstrak Purwaceng dan Ekstrak Pasak Bumi: Enhancement of Aphrodisiac Activity of Icariin, Purwaceng Extract, and Pasak Bumi Extract Microemulsion Ajeng Puspo Aji; Rochany Septianingsih; Septiana Indratmoko; Y, Asep Nurrahman; Lisa Indriana
Jurnal Tumbuhan Obat Indonesia Vol. 17 No. 1 (2024): July 2024
Publisher : Universitas Tidar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31002/jtoi.v17i1.984

Abstract

Erectile dysfunction (ED) refers to medical issues concerning men's sexual health. Purwaceng, pasak bumi, and epimedium plants contain aphrodisiac compounds that can boost stamina, libido (sexual desire), and male fertility. The formula for microemulsions is 80: PEG 400: oil shavings in a ratio of 73.6711: 12.5705: 13.7584, with icariin, purwaceng, and pasak bumi added. The microemulsion system was created because it contained a large number of active ingredients. The stability of a microemulsion is further influenced by surfactants (tween 80) and cosurfactants (PEG 400) as emulsifiers, as well as the oil used as a solvent for the active component (bottled oil). The goal of this study was to create a microemulsion that would mix icariin, pasak bumi, and purwaceng substances to improve solubility and synergize pharmacological effects. The formulation is optimized using Simplex Lattice Design (SLD) to produce the optimal formula. The microemulsion formulations of icariin, pasak bumi extract, and purwaceng extract produce optimal microemulsions and enter into good microemulsion susceptibility. They can also increase the aphrodisiac effectiveness when compared to the administration of the single active substance icariin, pasak bumi extract, and purwaceng extract. As a result, this product exhibits microemulsion capabilities, allowing it to minimize dose while increasing effect.
Formula Optimization of Propolis Transfersome Gel, Aloe Vera, Gotu Extract: Formula Design, Formulation Evaluation and Cell Regeneration Test in Diabetic Wounds Aji, Ajeng Puspo; Septiyaningsih, Rochany; Indratmoko, Septiana; Issusilaningtyas, Elisa; Nasikha, Solikhatun
Jurnal Penelitian Pendidikan IPA Vol 10 No 11 (2024): November
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i11.9283

Abstract

The study was conducted to determine the optimal formula of transfersome propolis gel, aloe vera extract and gotu gotu leaf extract and test it against diabetic wounds in male white rats (Rattus norvegicus). The gel was created with an optimal formulation resulting from the application of a Design Expert with Cutimed as a positive control of burns on the backs of male white rats (Rattus norvegicus). Formula optimization was carried out using a Simple Lattice Design with variations of carbopol, TEA and glycerin. Activity tests of propolis transferosome gel, aloe vera extract and gotu gotu extract were conducted on 20 rats. The data results were statistically analyzed using the SPSS One Way ANOVA method. Phytochemical screening on aloe vera and gotu gotu showed the presence of flavonoid compounds, tannins and saponins. Transfersome propolis has a particle size of 88.55 nm and a zeta potential of -24.13 mV. The optimal formula produces a clear preparation in white, a distinctive odour, a stable viscosity of 19980 cps, dispersion power of 6.67 cm, adhesion of 4.07 seconds and pH of 6.45. The burn activity test had the fastest effectiveness on day 12 but did not differ significantly from the customized control.
Co-Authors Amelia Amelia Andi Tenri Nurwahidah Anisa Putri Arianti Anita Ratna Faoziyah, Anita Ratna April Ningsih Dini Puspodewi Elisa Issusilaningtyas Fauziah, Anita Ratna Indah Ayu Agustin INDRA RACHMAWATI Isusilaningtyas, Elisa Lisa Indriana Nasikha, Solikhatun Nikmah Nuur Rochmah Palupi, Dhies Resty Pertiwi, Yuniariana Ratih Nugraheni, Devi Ratna Faoziah, Anita Rochany Septianingsih Rochmah, Nikmah Nuur Septiyaningsih, Rochany Setiyabudi, Lulu Susanti , Susanti Tajudin, Tatang Tatang Tajudin Wardani, Tri Kusuma Y, Asep Nurrahman Yogawati, Nursanti Dwi Yulianto, Asep Nurrahman Zetta, Darlene Nabila