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Nilai Rasio Neutrofil Limfosit (NLR) Terhadap Komorbid Hipertensi Pada Pasien Covid-19 Maulidiyanti, Ellies Tunjung Sari; Azizah, Fitrotin; Hidayat, Mariza; Purwaningsih, Nur Vita; Widiyastuti, Rahma
Camellia : Clinical, Pharmaceutical, Analytical and Pharmacy Community Journal Vol 2 No 1 (2023): Camellia (Clinical, Pharmaceutical, Analytical, and Pharmacy Community Journal)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/cam.v2i1.18806

Abstract

Tingkat kematian pasien Covid-19 lebih tinggi pada pasien yang memiliki komorbid dibandingkan dengan pasien tanpa komorbid dikarenakan imunitas yang lebih rendah. Kondisi dan tingkat keparahan infeksi dapat terjadi akibat peningkatan ikatan virus dengan sel target yang memanfaatkan ACE-2. Disfungsi endotel vascular pada pasien Covid-19 dengan komorbid hipertensi dapat meningkatkan keparahan infeksi hingga beresiko kematian. Hal itu terjadi karena pada pasien yang menderita hipertensi dapat meningkatkan ekspresi reseptor ACE-2 akibat disfungsi pada sel endotel vascular. Parameter pemeriksaan hematologi yang dapat digunakan untuk pemeriksaan adalah Nilai Rasio Limfosit/ Neutrophil Lymphocyte Ratio (NLR). NLR dapat digunakan untuk melihat dan memantau status inflamasi atau prediksi tingkat keparahan yang terjadi sebagai faktor resiko Covid-19. Tujuan dari penelitian ini adalah untuk mengetahui nilai NLR (Neutrophil Lymphocyte Ratio) pada pasien Covid-19 dengan komorbid hipertensi. Jenis penelitian yang digunakan adalah deskriptif, dengan sampel penelitian sebanyak 50 data pasien dalam kurun waktu 1 tahun (Desember 2020 - Desember 2021). Didapatkan hasil dari 50 data pasien yaitu sebanyak 26 pasien (52%) memiliki nilai NLR normal (<3,13) dan 24 pasien (48%) memiliki nilai NLR diatas nilai normal (>3,13), serta rata-rata nilai NLR dari 50 pasien Covid-19 dengan komorbid hipertensi adalah 4,13.
Kadar Glukosa Darah Pada Pasien Covid-19 Lanjut Usia Widyastuti, Rahma; Tunjung, Ellies Tunjung; Purwaningsih, Nur vita; Samsudin, Rinza Rahmawati
Indonesian Academia Health Sciences Journal Vol 4 No 1 (2023): Indonesian Academia Health Sciences Journal
Publisher : Universitas Muhammadiyah Surabaya

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Abstract

COVID-19 (Coronaviruses Disease 2019) is a disease caused by a new type of corona virus, namely Sars-CoV-2, was first reported in Wuhan, China on December 31 2019. The death rate in elderly patients continues to increase, accounting for 21.9% . COVID-19 risk assessments show that assessing blood glucose levels has the potential to better identify people at risk of adverse outcomes. Blood sugar levels are affected by a number of factors, including gender and age. At this point, elderly patients experience many physical and mental changes, especially the decline in individual functions and abilities in general. This study aims to describe the results of examining blood glucose levels in elderly COVID-19 patients at Brawijaya Hospital, Surabaya. This type of research is descriptive research with secondary data from the laboratory using total sampling technique. The sample in this study were 65 elderly patients who tested positive for COVID-19 who had blood glucose checked at the clinical pathology laboratory in the September- December 2020 period at Brawijaya Hospital, Surabaya. Variables are then grouped and then tabulated and displayed descriptively in percentage form. The results of this study were obtained from 65 elderly COVID-19 patients who had normal fasting blood glucose levels (<100 mg/dl) which was 6.15%, while those who had abnormal glucose levels (>100 mg/dl) were 93.85%. . These results indicate that the majority of elderly COVID-19 patients have abnormal blood glucose levels
Correlation Between ABO Blood Group and Activated Partial Thromboplastin Time (APTT) and Prothrombin Time (PT) Pathway Coagulation Parameters Saputro, Tri Ade; Purwaningsih, Nur Vita; Maulidiyanti, Ellies Tunjung Sari
jitek Vol 13 No 1 (2025): September 2025
Publisher : Poltekkes Kemenkes Jakarta III

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32668/jitek.v13i1.2074

Abstract

Background: The ABO blood group is known to affect the levels of several coagulation factors, such as factor VIII and von Willebrand factor (vWF), which can affect the results of coagulation time. This study aims to analyze the relationship between ABO blood group and the coagulation parameters Activated Partial Thromboplastin Time (APTT) and Prothrombin Time (PT). Methods: This analytical cross-sectional study involved 45 healthy Medical Laboratory Technology students from Muhammadiyah University of Surabaya. Inclusion criteria were healthy volunteers; exclusion criteria included bleeding disorders, recent transfusion, smoking, or refusal to consent. Conducted in May 2025 at the Clinical Pathology Laboratory, data were analyzed using one-way ANOVA. Ethical approval was obtained from KEPK FIK Muhammadiyah University of Surabaya (No. 057/KEPK/F/V/FIK/2025). Results: The test results showed that the distribution of APTT and PT data was normal and homogeneous. There was a significant difference between blood groups on APTT values (p = 0.006), but there was no significant difference on PT values (p = 0.605). Blood type O has a higher APTT value than other blood types. Conclusion: There is a significant relationship between ABO blood group and APTT values, but not with PT. The difference in APTT values may be influenced by lower vWF and factor VIII levels in blood group O. This finding is important to consider in the interpretation of coagulation test results in clinical laboratories.
STATUS KADAR TROMBOSIT AKIBAT PAPARAN PESTISIDA PADA PETANI Nur Vita Purwaningsih; Tri Ade Saputro; Ellies Tunjung SM; Rahma Widyastuti; Ainutajriani Ainutajriani; Baterun Kunsah
Klinikal Sains : Jurnal Analis Kesehatan Vol. 12 No. 1 (2024): Juni
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v12i1.4132

Abstract

Pesticides are substances or chemicals used in agriculture, forestry, horticulture and public land to increase crop yields. Up to now, pesticides are the main choice for farmers to protect plants from the influence of various plant-disturbing organisms. Exposure to pesticides on the body can have a negative impact on components in the body, including blood. Pesticides can be estimated as one of the factors that affect the blood profile, one of which is thrombocyte. The purpose of this study was to determine the description of platelet levels in farmers exposed to pesticides in Trece Village, Mojokerto Regency. This research was a descriptive study with an observational design. This research was conducted by checking the thrombocyte count of farmers in Trece Village, Mojokerto Regency, which was carried out automatically using a hematology analyzer. The results showed that the farmers of Trece Village, Mojokerto Regency who had normal platelet levels were 26 people with a percentage of 87% and 4 people with a low percentage of 13%. The conclusion in this study is that not all reductions in thrombocyte levels are due to exposure to pesticides and not always those who exposed to pesticides have low thrombocyte level.
EDUKASI DAN SKRINING LABORATORIUM JAMUR SUPERFISIAL PADA SWAB SELA JARI TANGAN MASYARAKAT Dita Artanti; Anindita Riesti Retno Arimurti; Yety Eka Sispita Sari; Fitrotin Azizah Fitrotin Azizah; Mulya Fitrah Juniawan; Ruspeni Daesusi; Nur Vita Purwaningsih; Tri Ade Saputro
Jurnal Abdi Masyarakat Kita Vol. 6 No. 2 (2026): Jurnal Abdi Masyarakat Kita
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/asta.v6i2.1039

Abstract

Superficial fungal infections remain a significant public health concern in tropical countries, including Indonesia. High humidity, intense physical activity, and inadequate personal hygiene increase the risk of fungal colonization on the skin, particularly in the interdigital spaces of the hands. Community education integrated with laboratory examination represents an effective preventive strategy to improve public awareness while enabling early detection of fungal colonization. This community service program aimed to improve participants' knowledge regarding the prevention of superficial fungal infections and to identify fungal colonization through interdigital hand swab examination. The activity was conducted at Yonif Kodam V/Brawijaya, Surabaya, in collaboration with the Bonek Bonita Surabaya community, involving 25 participants. Health education was delivered through interactive lectures and discussions covering risk factors, transmission, clinical manifestations, and preventive measures. Laboratory examination was performed using Sabouraud Dextrose Agar (SDA) culture followed by microscopic identification using 10% potassium hydroxide (KOH) preparation and Lactophenol Cotton Blue (LPCB) staining. Laboratory findings demonstrated fungal growth in 7 participants (28%), whereas 18 participants (72%) showed negative culture results. The isolated fungi were identified as Candida spp. and Aspergillus spp.. The educational intervention successfully enhanced participants' understanding of proper hand hygiene and the importance of early laboratory detection of superficial fungal infections. This collaborative program demonstrates that laboratory-based community education can serve as an effective model for promoting early detection and prevention of superficial fungal infections.