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All Journal Jurnal Sains Teknologi dan Lingkungan (JSTL) Manuju : Malahayati Nursing Journal Jurnal Gema Ngabdi Intan Husada : Jurnal Ilmiah Keperawatan Bioscientist : Jurnal Ilmiah Biologi MAHESA : Malahayati Health Student Journal Nusantara Hasana Journal Indonesian Journal of Cancer Jurnal Sehat Indonesia (JUSINDO) Journal of Innovative and Creativity Bali Dermatology Venereology and Aesthetic Journal
Hilda Santosa
Fakultas Kedokteran Universitas Islam Al-Azhar
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Adrenocortical Carcinoma with Infiltrated and Ruptured Inferior Vena Cava in Adult Woman Maligan, Deden Jinar Wahyudi; Maulana, Akhada; Danurdoro, Aria; Santosa, Hilda; Kumaladewi, Baiq Ratna
Indonesian Journal of Cancer Vol 19, No 4 (2025): December
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v19i4.1355

Abstract

Introduction: Adrenocortical carcinoma (ACC) is a malignant tumor that develops in the adrenal cortex. This case involves a rare, aggressive disease that demands specialized knowledge and optimal treatment for a favorable prognosis. This study aims to present the case of a woman with a right-sided ACC extending into the inferior vena cava (IVC), managed through radical resection and IVC repair.Case Presentation: A 50-year-old female presented with a complaint of a lump in the upper right abdomen, which she noticed three months ago. Abdominal computed tomography (CT) scan with contrast revealed a solid, inhomogeneous mass in the right suprarenal region measuring 12 cm x 11 cm. However, three days before the scheduled operation, the patient was brought to the emergency department with complaints of weakness and muscle weakness throughout the body. During the surgery, an adrenalectomy on the right side revealed a tumor infiltrating the IVC, causing venous rupture. The histological examination of the right adrenal tissue revealed ACC, infiltration of tumor cells beyond the capsule, lymphovascular infiltration, and no evidence of tumor cell infiltration into the kidney tissue. The treatment approach for this ACC case involved a complete surgical resection with open adrenalectomy and vena reconstruction. Postoperative results indicated improved patient condition, including symptom relief and favorable biochemical evaluation after surgery.Conclusion: Our patient had a right-sided ACC with local vascular infiltration into the IVC.
Urgensi Kebersihan Gigi dan Mulut sebagai Implementasi Thaharah Menurut Pandangan Aswaja Nining Handayani; Hilda Santosa; Selly Maulidina; Faiz Karim Fatkhullah
Journal of Innovative and Creativity Vol. 6 No. 1 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v6i1.6374

Abstract

Oral and dental health is frequently neglected in global public health priorities despite its profound impact on quality of life and socioeconomic burdens. This research aims to analyze the urgency of oral hygiene as an implementation of Thaharah within the Ahlussunnah wal Jamaah (Aswaja) framework, integrating theological and scientific perspectives. Employing a narrative review methodology, this study synthesizes classical Shafi'i jurisprudence and Al-Ghazali’s Sufism with contemporary biomedical data (2014-2025) sourced from Scopus and PubMed databases. The findings indicate that within the Aswaja tradition, oral hygiene transcends secular routines, functioning as a religious obligation with spiritual and metaphysical dimensions, including the sensitivity of angels to halitosis. Scientifically, the use of miswak (Salvadora persica) is validated through bioactive compounds such as benzyl isothiocyanate, fluoride, and silica, which exhibit potent antimicrobial properties and enamel protection. This integration reframes oral hygiene within the Maqasid Syariah (Objectives of Islamic Law), specifically Hifz al-Nafs (preservation of life/health) and Hifz al-Din (preservation of religion). The study concludes that evidence-based Islamic oral hygiene practices provide a holistic foundation for systemic health and the enhancement of religious devotion.
Hubungan Hipertensi, Obesitas dan Kadar HBA1C dengan Derajat Ulkus Kaki Diabetik Pada Pasien Diabetes Melitus Tipe 2 di RSUD Kota Mataram Kadek Dwi Gita Hapsary Dwija Putri; Mamang Bagiansah; Hilda Santosa; Aulia Mahdaniyati
Malahayati Nursing Journal Vol 7, No 4 (2025): Volume 7 Nomor 4 (2025)
Publisher : Universitas Malahayati Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mnj.v7i4.18841

Abstract

ABSTRACT Diabetic ulcer is an open wound on the skin's surface that develops as a complication of macroangiopathy, leading to vascular insufficiency and neuropathy. ulcers on the feet of diabetic patients are referred to as diabetic foot ulcers (DFU). several risk factors contribute to DFU, including hypertension, obesity, and HbA1c levels. The meggit-wagner classification is commonly used to assess lesions in DFU. Objective to determine the relationship between hypertension, obesity, and HbA1c levels with the degree of DFU in type 2 diabetes patients at the mataram city general hospital. Method this was an observational analytical study with a cross-sectional design. The sample in this study used total sampling, and 95 participants met the inclusion criteria. the statistical test used was the chi-square analysis. The results of the bivariate analysis showed hypertension had a relationship between the degree of UKD with p-value = 0.002 (PR= 1,882; 95% CI = 1,284-2,758), there is no relationship between obesity and the degree of UKD with p-value = 0.284 (PR= 1,276; 95% CI = 0,884-1,844) and there is a relationship between HbA1c levels and the degree of UKD with a p-value = 0.001 (PR= 4,962; 95% CI = 1,342-18,350). There is a relationship between hypertension and HbA1c levels with the degree of diabetic foot ulcers, but no relationship was found between obesity and the degree of diabetic foot ulcers in type 2 diabetes patients at the Mataram city general hospital. Keywords: Diabetic Foot Ulcers, Hypertension, Obesity, Hba1c Levels, Meggit-Wagner Classification  ABSTRAK Ulkus diabetik adalah luka terbuka pada permukaan kulit yang berkembang akibat komplikasi makroangiopati, yang menyebabkan insufisiensi vaskular dan neuropati. Ulkus pada bagian kaki penderita DM disebut dengan ulkus kaki diabetik (UKD). Terdapat beberapa faktor risiko yang menyebabkan UKD antara lain hipertensi, obesitas dan kadar HbA1c. Klasifikasi derajat UKD menurut Meggit-Wagner paling banyak digunakan untuk penilaian lesi pada UKD. Tujuan  penelitian ini untuk mengetahui hubungan antara hipertensi, obesitas dan kadar HbA1c dengan derajat UKD pada pasien DM tipe 2 di RSUD Kota Mataram. Metode Penelitian ini penelitian observasional analitik dengan desain penelitian cross-sectional. Adapun sampel dalam penelitian ini menggunakan teknik total sampling dan didapatkan hanya 95 orang yang termasuk pada kriteria inklusi. Uji statistik yang digunakan adalah uji analisis Chi-square. Hasil penelitian menunjukkan bahwa analisis bivariat didapatkan terdapat hubungan antara hipertensi dengan derajat UKD dengan p-value = 0,002 (PR= 1,882; 95% CI = 1,284-2,758), tidak terdapat hubungan antara obesitas dengan derajat UKD dengan p-value = 0,284 (PR= 1,276; 95% CI = 0,884-1,844) serta terdapat hubungan antara kadar HbA1c dengan derajat UKD dengan nilai Nilai p-value=0,001 (PR= 4,962; 95% CI = 1,342-18,350). Terdapat hubungan antara hipertensi dan kadar HbA1c dengan derajat ulkus kaki diabetik namun tidak terdapat hubungan antara obesitas dengan derajat ulkus kaki diabetik pada pasien diabetes melitus tipe 2 di RSUD Kota Mataram. Kata Kunci: Ulkus Kaki Diabetik, Hipertensi, Obesitas, Kadar Hba1c, Klasifikasi Meggit-Wagner
Co-Authors Akhada Maulana, Akhada Arsatt, Maz Isa Ansyori Aulia Mahdaniyati Bagus, Babad Danang Nur Adiwibawa Danurdoro, Aria Faiz Karim Fatkhullah Hidayat, Moulid I Putu Restu Surya Peraupan Ida Bagus Arya Ramatantra Imam, Lalu Yogi Prasetio Kadek Dwi Gita Hapsary Dwija Putri Kadek Dwi Pramana Karina Anindita Khairiyah, Dinur Kumaladewi, Baiq Ratna Made Agus Suanjaya Made Ardhia Santhi Pramesti Made Ayu Mirah Wulandari Made Ayu Mirah Wulandari Maligan, Deden Jinar Wahyudi Mamang Bagiansah Nadira Yumna Nidzarsyah, Muhammad Mirsa Nini, Cheryl Nining Handayani Perdana, Made Krisna Wahyu Perdana, Muhammad Astro Pramesti, Made Ardhia Santhi Prima Belia Fathana Putri, Adisti Prafica Putri, Wayan Julita Krisnanti Putu Ayu Egidea Restuningdyah, Novia Andansari Putri Rina Lestari Rizki Mulianti RR. Ella Evrita Hestiandari Sabariah Sabariah Selly Maulidina Setyobudi, Irwan Syuhada, Irwan Wardiana, Maya Widiasari, Komang Sri Rahayu Yumna, Nadira