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Perbandingan Aktivitas Antibakteri Ekstrak Bawang Tiwai (Eleutherine palmifolia (L.) Merr) dengan Pelarut Etil Asetat dan Etanol terhadap Pertumbuhan Bakteri Enterococcus faecalis Penyebab Infeksi Saluran Akar: Comparison of Antibacterial Activity of Tiwai Onion Extract (Eleutherine palmifolia (L.) Merr) with Ethyl Acetate and Ethanol Solvents Against the Growth of Enterococcus faecalis Bacteria Causing Root Canal Infection Samiaji, Airvin Wika; Yani, Sinar; Astuti, Lilies Anggarwati; Anitasari, Silvia; Yadi, Yadi
Jurnal Sains dan Kesehatan Vol. 7 No. 1 (2025): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v7i1.2363

Abstract

Pulp infection is capable of causing pulpitis, an inflammatory condition. Tiwai onion is known for its antibacterial properties. Compare the antibacterial activity of tiwai onion (Eleutherine palmifolia (L.) Merr) extract using ethyl acetate and ethanol solvents against Enterococcus faecalis bacteria causing root canal infection. Onion tiwai extract was prepared by maceration method using ethyl acetate and ethanol solvents. Activity test was determined by liquid and solid dilution method. In liquid dilution, there was no bacterial growth in ethyl acetate and ethanol extracts with a concentration of 20mg/ml. In the solid dilution test, the extract with ethyl acetate solvent showed a value of 20mg/ml, which means bactericidal. However, the ethanol solvent extract showed bacterial growth at a concentration of 20mg/ml, meaning it was not bactericidal. Onion tiwai  extracts with ethyl acetate and ethanol solvents showed different antibacterial activities against Enterococcus faecalis. Only extracts with ethyl acetate solvent showed bactericidal properties Keywords:          Eleutherine palmifolia (L) Merr, Enterococcus faecalis, ethanol, ethyl acetate, Pulpitis   Abstrak Infeksi pulpa mampu menyebabkan pulpitis, suatu kondisi peradangan. Bawang tiwai dikenal karena sifat antibakterinya. Tujuan penelitian ini adalah untuk membandingkan aktivitas antibakteri ekstrak bawang tiwai (Eleutherine palmifolia (L.) Merr) memakai pelarut etil asetat dan etanol terhadap bakteri Enterococcus faecalis penyebab infeksi saluran akar. Ekstrak bawang tiwai dibuat melewati metode maserasi dengan memakai pelarut etil asetat dan etanol. Uji aktivitas ditentukan dengan metode pengenceran cair dan metode pengenceran padat. Penelitian ini diperoleh hasil bahwa pada pengenceran cair, tak ada pertumbuhan bakteri pada ekstrak etil asetat dan etanol dengan konsentrasi 20mg/ml. Dalam uji pengenceran padat, ekstrak dengan pelarut etil asetat memperlihatkan nilai 20mg/ml, yang artinya bersifat bakterisidal. Namun, ekstrak dengan pelarut etanol memperlihatkan pertumbuhan bakteri pada konsentrasi 20mg/ml, artinya tidak bersifat bakterisidal. Ekstrak bawang tiwai (Eleutherine palmifolia (L.) Merr) dengan pelarut etil asetat dan etanol memperlihatkan aktivitas antibakteri yang berbeda terhadap Enterococcus faecalis. Hanya ekstrak dengan pelarut etil asetat yang memperlihatkan sifat bakterisidal. Kata Kunci:         Eleutherine palmifolia (L) Merr, Enterococcus faecalis, Etanol, Etil asetat, Pulpitis
Distribution of Mandibular Fractures Based on Age, Gender, Etiology, and Fracture Region at Abdoel Wahab Sjahranie Hospital Samarinda from 2019 to 2023 Gayatri, Amanda Putri; Pramasari, Cristiani Nadya; Cahya, Wahyuni Dwi; Anitasari, Silvia; Irawiraman, Hadi
Jurnal Sains dan Kesehatan Vol. 7 No. 1 (2025): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v7i1.2367

Abstract

Mandibular fracture is one of the fractures in the facial area and is most often caused by trauma. A hard impact to the face can result in a fracture of the mandible. This research aims to investigate the distribution of mandibular fracture based on age, gender, etiology, and fracture region at Abdoel Wahab Sjahranie Hospital Samarinda from 2019 to 2023. This research is quantitative research using descriptive observational research design. The results of this research showed that adolescent age from 12 to 25 years old was the age group in which mandibular fracture cases were found the most, with 34 cases (54%) in this research were from that age group. In terms of gender, mandibular fracture cases were found more in male samples, with 52 cases (82.5%) were male. Traffic accident was the most common etiology of mandibular fractures found, comprising of 47 cases (74.6%) from the total number of cases in this research. The most common fracture region found in this research was the parasymphysis region, with 13 cases (20.6%) in this research had parasymphyseal fracture.   Keywords:          Distribution, Mandibular Fracture, Mandibular Fracture Region
The difference of Heterotrigona itama honey gel degradation rate based on crystallinity index: Study experimental Alus, Levi Natya; Anitasari, Silvia; Kosala, Khemasili; Ismail, Sjarif; Yani, Sinar
Padjadjaran Journal of Dental Researchers and Students Vol 9, No 2 (2025): June 2025
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjdrs.v9i2.63110

Abstract

Domestic Environmental Factors Associated with Pediatric Snoring: A Scoping Review Protocol Supriatin, Supriatin; Wahyuni, Nuniek Tri; Widadi, Sri Yekti; Nurhaeni, Heni; Anitasari, Silvia
Poltekita : Jurnal Ilmu Kesehatan Vol. 17 No. 3 (2023): November
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v17i3.3268

Abstract

Since one-third of children who snore consistently may have OSAS, understanding the causes is vital. Preventing snoring requires addressing obesity, allergies, and anatomical anomalies. Indoor allergens and enlarged tonsils and adenoids may also cause youngsters to snore. The review aims to identify and categorize key concepts, types of evidence, and research gaps in this area.  The scoping review will follow the methodology and stages outlined by the Joana Briggs Institute ((JBI). The final output will follow the PRISMA-Protocols (PRISMA-P) 2015 checklist. This review serves as a necessary step before conducting a systematic review and clinical studies. Childhood snoring is a common problem that can have adverse effects on a child’s health and well-being. It is importing ant for parents to understand the hazards of snoring and seek support if they suspect their child may have a sleep disorder. Treatment options vary depending on the cause and severity of snoring, and may include lifestyle changes, medication, or surgery. More research is need to better understand the relationship between environmental factors and snoring children, including the impact of pollutant such as NO2 and passive smoking. Early detection and treatment of snoring in children is crucial, as if can have long-term effects on their health and well-being. The conclusion is that knowledge empowers parents to take the necessary steps to ensure the well-being and healthy sleep of their children.
ANALISIS PREFERENSI KONSUMEN DALAM MEMBELI MINYAK GORENG Larasati, Dyah Siti Ayu; Putri, Elvika Nungki Chintia; Kusuma, Bela; Anitasari, Silvia; meilina, Restin
Prosiding Seminar Nasional Manajemen, Ekonomi dan Akuntansi Vol. 7 (2022): PROSIDING SEMINAR NASIONAL MANAJEMEN, EKONOMI DAN AKUNTANSI 2022
Publisher : Universitas Nusantara PGRI Kediri

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Abstract As one of the nine urgently needed, consumption of cooking oil increased from year to year. In 2021 the demand for cooking oil in Indonesia was higher than the supply, resulting in a fairly high price increase. The government is trying to anticipate this by setting HET but instead it creates a shortage of products so that this policy is revoked except for bulk cooking oil. This makes cooking oil producers prefer to sell their products in packaging so that the selling price is higher. As a result, consumers face the choice of having to queue for hours to get bulk cooking oil or spend more money to buy packaged cooking oil whose price is quite large. The purpose of this study is to answer the problem formulation (1) How do packaging, price, size, clarity, color, nutritional information, promotion, brand, and accessibility become the basis for consumers to buy cooking oil? (2) How can the order of packaging, price, size, clarity, color, nutritional information, promotion, brand, and accessibility become the basis for consumers to buy cooking oil? (3) What is the most dominant attribute in buying cooking oil? and (4) Based on the attributes of packaging, price, size, clarity, color, nutritional information, promotion, brand, and accessibility, consumers are more dominant in choosing bulk or packaged cooking oil. The method used is descriptive qualitative through in-depth interviews with 3 informants. The results show that price is the most dominant attribute in buying cooking oil preferences. The order of these attributes is different for each informant, but the most dominant attribute is the same price. Based on the analysis of each attribute, consumer preference is higher for bulk cooking oil because the price is cheaper.  
Aktivitas antibakteri ekstrak tulang ikan patin (Pangasius djambal) terhadap pertumbuhan bakteri Fusobacterium nucleatum: Studi eksperimental Handayani, Fitri; Yani, Sinar; Anitasari, Silvia; Asfirizal, Verry; Agustin, Sylvia
Padjadjaran Journal of Dental Researchers and Students Vol 10, No 2 (2026): June 2026
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjdrs.v10i2.70379

Abstract

ABSTRAK Pendahuluan: Penyakit periodontal merupakan inflamasi kronis akibat biofilm bakteri. Salah satu bakterinya ialah Fusobacterium nucleatum yang dikenal sebagai bridging organism. Bakteri ini berperan dalam pembentukan biofilm dan progresivitas penyakit dan menunjukkan resistensi terhadap antibiotik. Tulang ikan patin (Pangasius djambal) mempunyai potensi sebagai antibakteri alami. Studi ini bertujuan mengevaluasi aktivitas antibakteri ekstrak tulang ikan patin terhadap Fusobacterium nucleatum berdasarkan nilai konsentrasi hambat minimum (KHM) dan konsentrasi bunuh minimum (KBM). Metode: Jenis metode studi kualitatif berupa true experimental memakai uji mikrodilusi. Terdapat 3 kelompok perlakuan, yakni kelompok uji ekstrak tulang ikan patin dengan konsentrasi 2,5%, 5%, 10%, 20%, 40% serta kelompok kontrol positif meliputi CHX 0,2% serta kelompok kontrol negatif meliputi PBS. Hasil: Ekstrak tulang ikan patin menunjukkan aktivitas antibakteri terhadap Fusobacterium nucleatum. Nilai KHM diperoleh pada konsentrasi 5%, yang ditandai dengan tidak adanya perubahan warna setelah penambahan MTT. Namun, nilai KBM tidak diperoleh pada seluruh rentang konsentrasi yang diuji karena masih ditemukan pertumbuhan bakteri pada media lanjutan. Simpulan: Ekstrak tulang ikan patin (Pangasius djambal) menunjukkan aktivitas penghambatan terhadap pertumbuhan Fusobacterium nucleatum dengan KHM sebesar 5%, sedangkan KBM tidak tercapai pada rentang konsentrasi yang diuji. KATA KUNCI: Antibakteri, tulang ikan patin, Fusobacterium nucleatum, KHM, KBMAntibacterial activity of catfish bone extract (pangasius djambal) against the growth of fusobacterium nucleatum: Study experimental  ABSTRACT Introduction: Periodontal disease is a chronic inflammatory condition caused by bacterial biofilm. One of the bacteria involved is Fusobacterium nucleatum, which is recognized as a bridging organism. This bacterium plays a role in biofilm formation and disease progression and has shown resistance to certain antibiotics. Catfish bone (Pangasius djambal) has potential as a natural antibacterial agent. This study aimed to evaluate the antibacterial activity of catfish bone extract against Fusobacterium nucleatum based on minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values. Methods: This study was a true experimental laboratory study using the microdilution method. The study consisted of three groups: the treatment group with catfish bone extract at concentrations of 2.5%, 5%, 10%, 20%, and 40%; the positive control group using chlorhexidine (CHX) 0.2%; and the negative control group using PBS. Results: Catfish bone extract demonstrated antibacterial activity against Fusobacterium nucleatum. The MIC was 5%, as indicated by the absence of color change after MTT addition. However, no MBC was identified within the tested concentration range, as bacterial growth was still observed on the subculture medium. Conclusions: Catfish bone extract (Pangasius djambal) demonstrated inhibitory activity against the growth of Fusobacterium nucleatum, with a MIC of 5%, whereas no MBC was identified within the concentration range tested.KEY WORDS: Antibacterial, catfish bone, Fusobacterium nucleatum, MIC, MBC
Antibacterial Activity Test of Pangasius djambal Fish Bone Extract Against Prevotella intermedia: An Experimental Study Dewi, Ni Made Puja Laksmi; Yani, Sinar; Anitasari, Silvia; Alhawaris, Alhawaris; Purnamasari, Cicih Bhakti
Padjadjaran Journal of Dental Researchers and Students Vol 10, No 3 (2026): Oktober 2026
Publisher : Fakultas Kedokteran Gigi Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/pjdrs.v10i3.70426

Abstract

ABSTRACT  Introduction: Periodontal disease is a common oral health problem in Indonesian society, often caused by anaerobic pathogenic bacteria such as Prevotella intermedia. The use of waste catfish (Pangasius djambal) bones as a natural antibacterial agent is an innovation that supports the concept of Green Dentistry because of their bioactive compounds. This study aimed to determine the antibacterial activity of Pangasius djambal fish bone extract against the growth of Prevotella intermedia. Methods: This study employed a laboratory experimental design using a post-test only control group design. The extraction was performed by ethanol maceration. The extract was tested at concentrations of 40%, 20%, 10%, 5%, 2.5%, 1.25%, and 0.625%. Antibacterial activity was evaluated using the microdilution method to determine the Minimum Inhibitory Concentration (MIC) and subculture medium for the Minimum Bactericidal Concentration (MBC). Results: The ethanol extract of catfish bones exhibited an MIC of 5%, as indicated by the absence of color change in the wells after the addition of MTT stain. In the subculture test, no bacterial growth was observed in any replicate at a concentration of 20%, establishing the MBC at 20%. Conclusions: The ethanol extract of catfish bones exhibited antibacterial activity against Prevotella intermedia, with an MIC of 5% and an MBC of 20%.KEYWORDS : Antibacterial activity, Pangasius djambal, Prevotella intermedia, macerationUji aktivitas antibakteri ekstrak tulang ikan patin terhadap Prevotella intermedia: Studi eksperimentalABSTRAK Pendahuluan: Penyakit periodontal merupakan masalah kesehatan gigi yang umum di masyarakat Indonesia, sering kali disebabkan oleh aktivitas bakteri patogen anaerob seperti Prevotella intermedia. Pemanfaatan limbah tulang ikan patin (Pangasius djambal) sebagai agen antibakteri alami merupakan inovasi yang mendukung konsep Green Dentistry karena kandungan senyawa bioaktifnya. Penelitian ini bertujuan untuk mengetahui aktivitas antibakteri ekstrak tulang Pangasius djambal terhadap pertumbuhan bakteri Prevotella intermedia. Metode: Penelitian ini menggunakan jenis penelitian eksperimental laboratoris dengan desain penelitian post-test only control group design. Metode ekstraksi yang digunakan dalam proses ini, yaitu maserasi (etanol) pada rentang konsentrasi 40%, 20%, 10%, 5%, 2,5%, 1,25%, dan 0,625%. Uji aktivitas antibakteri dilakukan menggunakan metode mikrodilusi untuk menentukan Konsentrasi Hambat Minimum (KHM) dan media subkultur untuk Konsentrasi Bunuh Minimum (KBM). Hasil: Ekstrak etanol tulang ikan patin memiliki nilai KHM 5% dilihat dari sumuran yang tidak mengalami perubahan warna setelah diberi pewarna MTT. Pada uji subkultur tidak ditemukan pertumbuhan bakteri pada seluruh replikasi pada konsentrasi 20%. Simpulan: Ekstrak etanol tulang ikan patin memiliki aktivitas antibakteri terhadap bakteri Prevotella intermedia dengan nilai KHM 5% dan KBM 20%.KATA KUNCI : aktivitas antibakteri, pangasius djambal, prevotella intermedia, maserasi